Roman Lesyk

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Venues

Molecules (Basel, Switzerland)

International journal of molecular sciences

Pharmacy (Basel, Switzerland)

Archiv der Pharmazie

Danylo Halytsky Lviv National Medical Univeristy

Danylo Halytsky Lviv National Medical University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Danylo Halytsky Lviv National Medical Univeristy May 01 2005

Ukraine

Professor, Head of the Department :: Pharmaceutical, Organic and Bioorganic Chemistry

Education History

Danylo Halytsky Lviv National Medical University Nov 01 1993 - Oct 31 1996

Ukraine

PHD :: Department of Pharmaceutical, Organic and Bioorganic Chemistry

Danylo Halytsky Lviv National Medical University Sep 01 1986 - Jun 26 1993

Ukraine

MSC :: Faculty of Pharmacy

Publications

Sara Janowska, Serhii Holota, Roman Lesyk, Monika Wujec
Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs. Molecules (Basel, Switzerland) 29 (2) (2024)
Natalia Tkachenko, Ostap Pankevych, Tamara Mahanova, Bohdan Hromovyk, Roman Lesyk, Lilia Lesyk
Human Healthcare and Its Pharmacy Component from a Safety Point of View. Pharmacy (Basel, Switzerland) 12 (2) (2024)
Karolina Kosińska, Bartosz Skóra, Serhii Holota, Yulia Shepeta, Anna Tabęcka-Łonczyńska, Roman Lesyk, Konrad A Szychowski
Role of 4-Thiazolidinone-Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines. Cells 13 (12) (2024)
Yulian Konechnyi, Tetyana Rumynska, Ihor Yushyn, Serhii Holota, Vira Turkina, Mariana Ryviuk Rydel, Alicja Sękowska, Yuriy Salyha, Olena Korniychuk, Roman Lesyk
A New 4-Thiazolidinone Derivative (Les-6490) as a Gut Microbiota Modulator: Antimicrobial and Prebiotic Perspectives. Antibiotics (Basel, Switzerland) 13 (4) (2024)
Natalia Tkachenko, Ostap Pankevych, Tamara Mahanova, Bohdan Hromovyk, Roman Lesyk, Lilia Lesyk
Human Healthcare and Its Pharmacy Component from a Safety Point of View. Pharmacy (Basel, Switzerland) 12 (2) (2024)
Sara Janowska, Serhii Holota, Roman Lesyk, Monika Wujec
Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs. Molecules (Basel, Switzerland) 29 (2) (2024)
Sara Janowska, Serhii Holota, Roman Lesyk, Monika Wujec
Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs. Molecules (Basel, Switzerland) 29 (2) (2024)
Dominika Szlachcikowska, Anna Tabęcka-Łonczyńska, Serhii Holota, Olexandra Roman, Yulia Shepeta, Roman Lesyk, Konrad A Szychowski
Role of Ciminalum-4-thiazolidinone Hybrids in Molecular NF-κB Dependent Pathways. International journal of molecular sciences 25 (13) (2024)
Dominika Szlachcikowska, Anna Tabęcka-Łonczyńska, Serhii Holota, Olexandra Roman, Yulia Shepeta, Roman Lesyk, Konrad A Szychowski
Role of Ciminalum-4-thiazolidinone Hybrids in Molecular NF-κB Dependent Pathways. International journal of molecular sciences 25 (13) (2024)
Karolina Kosińska, Bartosz Skóra, Serhii Holota, Yulia Shepeta, Anna Tabęcka-Łonczyńska, Roman Lesyk, Konrad A Szychowski
Role of 4-Thiazolidinone-Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines. Cells 13 (12) (2024)
Nataliya Finiuk, Yuliia Kozak, Agnieszka Gornowicz, Robert Czarnomysy, Marlena Tynecka, Serhii Holota, Marcin Moniuszko, Rostyslav Stoika, Roman Lesyk, Krzysztof Bielawski, Anna Bielawska
The Proapoptotic Action of Pyrrolidinedione-Thiazolidinone Hybrids towards Human Breast Carcinoma Cells Does Not Depend on Their Genotype. Cancers 16 (16) (2024)
Yulian Konechnyi, Tetyana Rumynska, Ihor Yushyn, Serhii Holota, Vira Turkina, Mariana Ryviuk Rydel, Alicja Sękowska, Yuriy Salyha, Olena Korniychuk, Roman Lesyk
A New 4-Thiazolidinone Derivative (Les-6490) as a Gut Microbiota Modulator: Antimicrobial and Prebiotic Perspectives. Antibiotics (Basel, Switzerland) 13 (4) (2024)
Sara Janowska, Serhii Holota, Roman Lesyk, Monika Wujec
Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs. Molecules (Basel, Switzerland) 29 (2) (2024)
Dominika Szlachcikowska, Anna Tabęcka-Łonczyńska, Serhii Holota, Olexandra Roman, Yulia Shepeta, Roman Lesyk, Konrad A Szychowski
Role of Ciminalum-4-thiazolidinone Hybrids in Molecular NF-κB Dependent Pathways. International journal of molecular sciences 25 (13) (2024)
Eduard Davydov, Mykhailo Hoidyk, Sergiy Shtrygol', Andriy Karkhut, Svyatoslav Polovkovych, Olga Klyuchivska, Olexandr Karpenko, Roman Lesyk, Serhii Holota
Evaluation of thiopyrano[2,3-d]thiazole derivatives as potential anticonvulsant agents. Archiv der Pharmazie (2024)
Nataliya Finiuk, Yuliia Kozak, Agnieszka Gornowicz, Robert Czarnomysy, Marlena Tynecka, Serhii Holota, Marcin Moniuszko, Rostyslav Stoika, Roman Lesyk, Krzysztof Bielawski, Anna Bielawska
The Proapoptotic Action of Pyrrolidinedione-Thiazolidinone Hybrids towards Human Breast Carcinoma Cells Does Not Depend on Their Genotype. Cancers 16 (16) (2024)
Natalia Tkachenko, Ostap Pankevych, Tamara Mahanova, Bohdan Hromovyk, Roman Lesyk, Lilia Lesyk
Human Healthcare and Its Pharmacy Component from a Safety Point of View. Pharmacy (Basel, Switzerland) 12 (2) (2024)
Stepan Sysak, Beata Czarczynska-Goslinska, Piotr Szyk, Tomasz Koczorowski, Dariusz T Mlynarczyk, Wojciech Szczolko, Roman Lesyk, Tomasz Goslinski
Metal Nanoparticle-Flavonoid Connections: Synthesis, Physicochemical and Biological Properties, as Well as Potential Applications in Medicine. Nanomaterials (Basel, Switzerland) 13 (9) (2023)
Olga Klaudia Szewczyk-Roszczenko, Piotr Roszczenko, Anna A Shmakova, Nataliya Finiuk, Serhii Holota, Roman Lesyk, Anna Bielawska, Yegor S Vassetzky, Krzysztof Bielawski
The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications. Cells 12 (18) (2023)
Stepan Sysak, Beata Czarczynska-Goslinska, Piotr Szyk, Tomasz Koczorowski, Dariusz T Mlynarczyk, Wojciech Szczolko, Roman Lesyk, Tomasz Goslinski
Metal Nanoparticle-Flavonoid Connections: Synthesis, Physicochemical and Biological Properties, as Well as Potential Applications in Medicine. Nanomaterials (Basel, Switzerland) 13 (9) (2023)
Agnieszka Gornowicz, Roman Lesyk, Robert Czarnomysy, Serhii Holota, Yulia Shepeta, Bożena Popławska, Magdalena Podolak, Wojciech Szymanowski, Krzysztof Bielawski, Anna Bielawska
Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells. International journal of molecular sciences 24 (7) (2023)
Andrii Pyrih, Andrzej Łapiński, Sylwia Zięba, Adam Mizera, Roman Lesyk, Mariusz Jaskolski, Andrzej K Gzella
Proton tautomerism in 5-dimethylaminomethylidene-4-(o-,m-,p-hydroxyphenyl)amino-1,3-thiazol-2(5H)-ones: synthesis, crystal structure and spectroscopic studies. Acta crystallographica Section B, Structural science, crystal engineering and materials (2023)
Andrii Pyrih, Andrzej Łapiński, Sylwia Zięba, Adam Mizera, Roman Lesyk, Andrzej K Gzella, Mariusz Jaskolski
Proton tautomerism and stereoisomerism in 5-[(dimethylamino)methylidene]-4-[3/4-(trifluoromethylphenyl)amino]-1,3-thiazol-2(5H)-ones: synthesis, crystal structure and spectroscopic studies. Acta crystallographica. Section C, Structural chemistry (2023)
Аkzhonas Khamitova, Dmitriy A Berillo, Andrii Lozynskyi, Yulian Konechnyi, Dmytro Mural, Victoriya A Georgiyants, Roman Lesyk
Thiadiazole and Thiazole Derivatives as Potential Antimicrobial Agents. Mini reviews in medicinal chemistry (2023)
Jiri Rehulka, Ivanna Subtelna, Anna Kryshchyshyn-Dylevych, Alina Cherniienko, Aleksandra Ivanova, Mariia Matveieva, Pavel Polishchuk, Sona Gurska, Marian Hajduch, Oleh Zagrijtschuk, Petr Dzubak, Roman Lesyk
Anticancer 5-arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones as tubulin inhibitors. Archiv der Pharmazie 355 (12) (2022)
Kamila Buzun, Agnieszka Gornowicz, Roman Lesyk, Anna Kryshchyshyn-Dylevych, Andrzej K Gzella, Robert Czarnomysy, Gniewomir Latacz, Agnieszka Olejarz-Maciej, Jadwiga Handzlik, Krzysztof Bielawski, Anna Bielawska
2-{5-[( Z ,2 Z )-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule. International journal of molecular sciences 23 (8) (2022)
Christian Pecquet, Nicolas Papadopoulos, Thomas Balligand, Ilyas Chachoua, Amandine Tisserand, Gaëlle Vertenoeil, Audrey Nédélec, Didier Vertommen, Anita Roy, Caroline Marty, Harini Nivarthi, Jean-Philippe Defour, Mira El-Khoury, Eva Hug, Andrea Majoros, Erica Xu, Oleh Zagrijtschuk, Tudor Emanuel Fertig, Daciana S Marta, Heinz Gisslinger, Bettina Gisslinger, Martin Schalling, Ilaria Carola Casetti, Elisa Rumi, Daniela Pietra, Chiara Cavalloni, Luca Arcaini, Mario Cazzola, Norio Komatsu, Yoshihiko Kihara, Yoshitaka Sunami, Yoko Edahiro, Marito Araki, Roman Lesyk, Veronika Buxhofer-Ausch, Sonja Heibl, Florence Pasquier, Isabelle Plo, William Vainchenker, Robert Kralovics, Stefan N Constantinescu
Secreted Mutant Calreticulins As Rogue Cytokines in Myeloproliferative Neoplasms. Blood (2022)
Iryna Ivasechko, Ihor Yushyn, Piotr Roszczenko, Julia Senkiv, Nataliya Finiuk, Danylo Lesyk, Serhii Holota, Robert Czarnomysy, Olga Klyuchivska, Dmytro Khyluk, Nataliya Kashchak, Andrzej Gzella, Krzysztof Bielawski, Anna Bielawska, Rostyslav Stoika, Roman Lesyk
Development of Novel Pyridine-Thiazole Hybrid Molecules as Potential Anticancer Agents. Molecules (Basel, Switzerland) 27 (19) (2022)
Piotr Roszczenko, Serhii Holota, Olga Klaudia Szewczyk-Roszczenko, Rostyslav Dudchak, Krzysztof Bielawski, Anna Bielawska, Roman Lesyk
4-Thiazolidinone-Bearing Hybrid Molecules in Anticancer Drug Design. International journal of molecular sciences 23 (21) (2022)
Bartosz Skóra, Anna Lewinska, Anna Kryshchyshyn-Dylevych, Danylo Kaminskyy, Roman Lesyk, Konrad A Szychowski
Evaluation of Anticancer and Antibacterial Activity of Four 4-Thiazolidinone-Based Derivatives. Molecules (Basel, Switzerland) 27 (3) (2022)
Andrii Lozynskyi, Julia Senkiv, Iryna Ivasechko, Nataliya Finiuk, Olga Klyuchivska, Nataliya Kashchak, Danylo Lesyk, Andriy Karkhut, Svyatoslav Polovkovych, Oksana Levytska, Olexandr Karpenko, Assyl Boshkayeva, Galiya Sayakova, Andrzej Gzella, Rostyslav Stoika, Roman Lesyk
1,4-Naphthoquinone Motif in the Synthesis of New Thiopyrano[2,3- d ]thiazoles as Potential Biologically Active Compounds. Molecules (Basel, Switzerland) 27 (21) (2022)
Kamila Buzun, Agnieszka Gornowicz, Roman Lesyk, Krzysztof Bielawski, Anna Bielawska
Autophagy Modulators in Cancer Therapy. International journal of molecular sciences 22 (11) (2021)
Kamila Buzun, Anna Kryshchyshyn-Dylevych, Julia Senkiv, Olexandra Roman, Andrzej Gzella, Krzysztof Bielawski, Anna Bielawska, Roman Lesyk
Synthesis and Anticancer Activity Evaluation of 5-[2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-thiazolidinones. Molecules (Basel, Switzerland) 26 (10) (2021)
Serhii Holota, Sergiy Komykhov, Stepan Sysak, Andrzej Gzella, Andriy Cherkas, Roman Lesyk
Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents. Molecules (Basel, Switzerland) 26 (4) (2021)
Sergii Demchenko, Roman Lesyk, Oleh Yadlovskyi, Johannes Zuegg, Alysha G Elliott, Iryna Drapak, Yuliia Fedchenkova, Zinaida Suvorova, Anatolii Demchenko
Synthesis, Antibacterial and Antifungal Activity of New 3-Aryl-5H-pyrrolo[1,2-a]imidazole and 5H-Imidazo[1,2-a]azepine Quaternary Salts. Molecules (Basel, Switzerland) 26 (14) (2021)
Ivanna Subtelna, Anna Kryshchyshyn, Ruochen Jia, Maryan Lelyukh, Anna Ringler, Stefan Kubicek, Oleh Zagrijtschuk, Robert Kralovics, Roman Lesyk
5-Arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones with selective inhibitory activity against some leukemia cell lines. Archiv der Pharmazie 354 (4) (2020)
Konrad A Szychowski, Bartosz Skóra, Anna Kryshchyshyn, Danylo Kaminskyy, Kamila Rybczyńska-Tkaczyk, Roman Lesyk, Jan Gmiński
Induction of Cyp450 enzymes by 4-thiazolidinone-based derivatives in 3T3-L1 cells in vitro. Naunyn-Schmiedeberg's archives of pharmacology 394 (5) (2020)
Anna Kryshchyshyn, Danylo Kaminskyy, Igor Nektegayev, Philippe Grellier, Roman Lesyk
Isothiochromenothiazoles-A Class of Fused Thiazolidinone Derivatives with Established Anticancer Activity That Inhibits Growth of Trypanosoma brucei brucei. Scientia pharmaceutica 86 (4) (2018)
Anna Kryshchyshyn, Olexandra Roman, Andrii Lozynskyi, Roman Lesyk
Thiopyrano[2,3-d]Thiazoles as New Efficient Scaffolds in Medicinal Chemistry. Scientia pharmaceutica 86 (2) (2018)
Danylo Kaminskyy, Anna Kryshchyshyn, Roman Lesyk
Recent developments with rhodanine as a scaffold for drug discovery. Expert opinion on drug discovery 12 (12) (2017)
Andrii Lozynskyi, Viktoria Zasidko, Dmytro Atamanyuk, Danylo Kaminskyy, Halyna Derkach, Olexandr Karpenko, Volodymyr Ogurtsov, Roman Kutsyk, Roman Lesyk
Synthesis, antioxidant and antimicrobial activities of novel thiopyrano[2,3-d]thiazoles based on aroylacrylic acids. Molecular diversity 21 (2) (2017)
Anna Kryshchyshyn, Oleg Devinyak, Danylo Kaminskyy, Philippe Grellier, Roman Lesyk
Development of Predictive QSAR Models of 4-Thiazolidinones Antitrypanosomal Activity Using Modern Machine Learning Algorithms. Molecular informatics 37 (5) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Roman Lesyk