James L Hougland

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Venues

International journal of molecular sciences

Biochemistry

ACS chemical biology

The Journal of biological chemistry

Syracuse University

University of Chicago (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Syracuse University Aug 23 2016

United States

Associate Professor :: Chemistry

Syracuse University Aug 23 2010 - Aug 22 2016

United States

Assistant Professor :: Chemistry

University of Michigan Sep 06 2005 - Aug 10 2010

United States

Postdoctoral Fellow :: Chemistry

Education History

University of Chicago Aug 01 1998 - Aug 26 2005

United States

PHD :: Chemistry

Northwestern University Sep 01 1994 - Jun 01 1998

United States

BSC

Publications

Garrett L Schey, Emily R Hildebrandt, You Wang, Safwan Diwan, Holly A Passetti, Gavin W Potts, Andrea M Sprague-Getsy, Ethan R Leoni, Taylor S Kuebler, Yuk Yin Sham, James L Hougland, Lorena S Beese, Walter K Schmidt, Mark D Distefano
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase. International journal of molecular sciences 25 (10) (2024)
Garrett L Schey, Emily R Hildebrandt, You Wang, Safwan Diwan, Holly A Passetti, Gavin W Potts, Andrea M Sprague-Getsy, Ethan R Leoni, Taylor S Kuebler, Yuk Yin Sham, James L Hougland, Lorena S Beese, Walter K Schmidt, Mark D Distefano
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase. International journal of molecular sciences 25 (10) (2024)
Maria B Campaña, Tasha R Davis, Sadie X Novak, Elizabeth R Cleverdon, Michael Bates, Nikhila Krishnan, Erin R Curtis, Marina D Childs, Mariah R Pierce, Yasandra Morales-Rodriguez, Michelle A Sieburg, Heidi Hehnly, Leonard G Luyt, James L Hougland
Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin O -Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme. ACS chemical biology (2023)
Mariah R Pierce, Jingjing Ji, Sadie X Novak, Michelle A Sieburg, Shivangi Nangia, Shikha Nangia, James L Hougland
Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization. Journal of chemical information and modeling (2023)
Katarzyna Justyna, Riki Das, Ellen L Lorimer, Jiayue Hu, Jodi S Pedersen, Andrea M Sprague-Getsy, Garrett L Schey, Michelle A Sieburg, Olivia J Koehn, Yen-Chih Wang, Yong Xiang Chen, James L Hougland, Carol L Williams, Mark D Distefano
Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues. Organic letters (2023)
Johannes Morstein, Taysir Bader, Ariana L Cardillo, Julian Schackmann, Sudhat Ashok, James L Hougland, Christine A Hrycyna, Dirk H Trauner, Mark D Distefano
Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation. ACS chemical biology 17 (10) (2022)
Md Shahadat Hossain, Zhe Zhang, Sudhat Ashok, Ashley R Jenks, Christopher J Lynch, James L Hougland, Davoud Mozhdehi
Temperature-Responsive Nano-Biomaterials from Genetically Encoded Farnesylated Disordered Proteins. ACS applied bio materials 5 (5) (2022)
Garrett L Schey, Peter H Buttery, Emily R Hildebrandt, Sadie X Novak, Walter K Schmidt, James L Hougland, Mark D Distefano
MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase. International journal of molecular sciences 22 (21) (2021)
Sara L Deschaine, Mehdi Farokhnia, Adriana Gregory-Flores, Lia J Zallar, Zhi-Bing You, Hui Sun, Deon M Harvey, Renata C N Marchette, Brendan J Tunstall, Bharath K Mani, Jacob E Moose, Mary R Lee, Eliot Gardner, Fatemeh Akhlaghi, Michael Q Steinman, James L Hougland, Jeffrey M Zigman, George F Koob, Leandro F Vendruscolo, Lorenzo Leggio
A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data. Addiction biology (2021)
Sudhat Ashok, Emily R Hildebrandt, Colby S Ruiz, Daniel S Hardgrove, David W Coreno, Walter K Schmidt, James L Hougland
Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences. Biochemistry 59 (11) (2020)
Yiao Wang, Ozgun Kilic, Clifford M Csizmar, Sudhat Ashok, James L Hougland, Mark D Distefano, Carston R Wagner
Engineering reversible cell-cell interactions using enzymatically lipidated chemically self-assembled nanorings. Chemical science 12 (1) (2020)
Jacob E Moose, Katelyn A Leets, Nilamber A Mate, John D Chisholm, James L Hougland
An overview of ghrelin O-acyltransferase inhibitors: a literature and patent review for 2010-2019. Expert opinion on therapeutic patents 30 (8) (2020)
Maria B Campaña, Flaviyan Jerome Irudayanathan, Tasha R Davis, Kayleigh R McGovern-Gooch, Rosemary Loftus, Mohammad Ashkar, Najae Escoffery, Melissa Navarro, Michelle A Sieburg, Shikha Nangia, James L Hougland
The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation. The Journal of biological chemistry 294 (39) (2019)
James L Hougland
Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling. Biochemical Society transactions 47 (1) (2019)
Brittany M Berger, June H Kim, Emily R Hildebrandt, Ian C Davis, Michael C Morgan, James L Hougland, Walter K Schmidt
Protein Isoprenylation in Yeast Targets COOH-Terminal Sequences Not Adhering to the CaaX Consensus. Genetics 210 (4) (2018)
Elizabeth R Cleverdon, Kayleigh R McGovern-Gooch, James L Hougland
The octanoylated energy regulating hormone ghrelin: An expanded view of ghrelin's biological interactions and avenues for controlling ghrelin signaling. Molecular membrane biology 33 (6-8) (2017)
Kayleigh R McGovern-Gooch, Nivedita S Mahajani, Ariana Garagozzo, Anthony J Schramm, Lauren G Hannah, Michelle A Sieburg, John D Chisholm, James L Hougland
Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation. Biochemistry 56 (7) (2017)
Agnesa Shala-Lawrence, Melanie J Blanden, Svetlana M Krylova, Soumyashree A Gangopadhyay, Stanislav S Beloborodov, James L Hougland, Sergey N Krylov
Simultaneous Analysis of a Non-Lipidated Protein and Its Lipidated Counterpart: Enabling Quantitative Investigation of Protein Lipidation's Impact on Cellular Regulation. Analytical chemistry 89 (24) (2017)

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Publication Activity (10 Years)

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James L Hougland