Lorenzo Leggio (L Leggio)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 85

Top Topics

Prefrontal Cortex

Magnetic Resonance

Alcohol Use Disorder

Top Venues

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Alcoholism, clinical and experimental research

Addiction (Abingdon, England)

Addiction biology

This page only lists publications with an associated author ORCID identifier.

Publications

András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Lamia Y Haque, Lorenzo Leggio
Integrated and collaborative care across the spectrum of alcohol-associated liver disease and alcohol use disorder. Hepatology (Baltimore, Md.) (2024)
András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (6) (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (6) (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Ryan E Tyler, Lorenzo Leggio
Biological basis of addiction and alcohol use disorder. Clinical liver disease 23 (1) (2024)
Lorenzo Leggio
Welcome to Giancarlo Colombo, new editor-in-chief of Alcohol and Alcoholism. Alcohol and alcoholism (Oxford, Oxfordshire) 59 (2) (2024)
András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Luis Antonio Diaz, Juan Pablo Arab, Lorenzo Leggio
Granulocyte-colony stimulating factor use in alcohol-associated hepatitis: is it time to promote liver regeneration? The American journal of drug and alcohol abuse 50 (2) (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) (2024)
Daria Piacentino, Carlotta Vizioli, Jennifer J Barb, Silvia Beurmann, Sofia Bouhlal, Jillian T Battista, Olivia Jennings, Mary R Lee, Melanie L Schwandt, Peter J Walter, Wendy A Henderson, Kun Chen, Sara Turner, Shanna Yang, Claire M Fraser, Lisa A Farinelli, Mehdi Farokhnia, Lorenzo Leggio
Gut microbial diversity and functional characterization in people with alcohol use disorder: A case-control study. PloS one 19 (6) (2024)
Ryan E Tyler, Lorenzo Leggio
Biological basis of addiction and alcohol use disorder. Clinical liver disease 23 (1) (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (6) (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (6) (2024)
András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Luis Antonio Diaz, Juan Pablo Arab, Lorenzo Leggio
Granulocyte-colony stimulating factor use in alcohol-associated hepatitis: is it time to promote liver regeneration? The American journal of drug and alcohol abuse 50 (2) (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Luis Antonio Diaz, Juan Pablo Arab, Lorenzo Leggio
Granulocyte-colony stimulating factor use in alcohol-associated hepatitis: is it time to promote liver regeneration? The American journal of drug and alcohol abuse (2024)
Rani S Richardson, Lindsay A Kryszak, Janaina C M Vendruscolo, George F Koob, Leandro F Vendruscolo, Lorenzo Leggio
GHSR blockade, but not reduction of peripherally circulating ghrelin via β 1 -adrenergic receptor antagonism, decreases binge-like alcohol drinking in mice. Molecular psychiatry (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (6) (2024)
Lorenzo Leggio, Giancarlo Colombo
On the retirement of Jonathan Chick, Editor-in-Chief of Alcohol and Alcoholism: a fond and grateful farewell. Alcohol and alcoholism (Oxford, Oxfordshire) 59 (2) (2024)
Daria Piacentino, Carlotta Vizioli, Jennifer J Barb, Silvia Beurmann, Sofia Bouhlal, Jillian T Battista, Olivia Jennings, Mary R Lee, Melanie L Schwandt, Peter J Walter, Wendy A Henderson, Kun Chen, Sara Turner, Shanna Yang, Claire M Fraser, Lisa A Farinelli, Mehdi Farokhnia, Lorenzo Leggio
Gut microbial diversity and functional characterization in people with alcohol use disorder: A case-control study. PloS one 19 (6) (2024)
Michal Pietrzak, Adam Yngve, Paul J Hamilton, Anna Asratian, Emelie Gauffin, Andreas Löfberg, Sarah Gustavson, Emil Persson, Andrea J Capusan, Lorenzo Leggio, Irene Perini, Gustav Tinghög, Markus Heilig, Rebecca Boehme
Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Masoumeh Aminesmaeili, Mehdi Farokhnia, Ryoko Susukida, Lorenzo Leggio, Renee M Johnson, Rosa M Crum, Ramin Mojtabai
Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England) 119 (5) (2024)
Carolina L Haass-Koffler, Molly Magill, Nazzareno Cannella, Joshua C Brown, Elie G Aoun, Patricia A Cioe, Rajita Sinha, Robert M Swift, Roberto Ciccocioppo, Lorenzo Leggio
Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Addiction biology 28 (7) (2023)
Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Lee
Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry 13 (1) (2023)
Luis Antonio Diaz, Gerald Scott Winder, Lorenzo Leggio, Jasmohan Singh Bajaj, Ramon A Bataller, Juan Pablo Arab
New insights into the molecular basis of alcohol abstinence and relapse in alcohol-associated liver disease. Hepatology (Baltimore, Md.) (2023)
Andras H Leko, Lara A Ray, Lorenzo Leggio
The vicious cycle between (neuro)inflammation and alcohol use disorder: An opportunity toward the development of new medications? Alcoholism, clinical and experimental research (2023)
Madeline E Crozier, Mehdi Farokhnia, Susan Persky, Lorenzo Leggio, Brenda L Curtis
Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving. BMJ mental health 26 (1) (2023)
András H Lékó, Lara A Ray, Lorenzo Leggio
The vicious cycle between (neuro)inflammation and alcohol use disorder: An opportunity to develop new medications? Alcoholism, clinical and experimental research (2023)
Carolina L Haass-Koffler, Molly Magill, Nazzareno Cannella, Joshua C Brown, Elie G Aoun, Patricia A Cioe, Rajita Sinha, Robert M Swift, Roberto Ciccocioppo, Lorenzo Leggio
Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Addiction biology 28 (7) (2023)
Carolina L Haass-Koffler, Molly Magill, Nazzareno Cannella, Joshua C Brown, Elie G Aoun, Patricia A Cioe, Rajita Sinha, Robert M Swift, Roberto Ciccocioppo, Lorenzo Leggio
Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Addiction biology 28 (7) (2023)
Lorenzo Leggio, Christian S Hendershot, Mehdi Farokhnia, Anders Fink-Jensen, Mette Kruse Klausen, Joseph P Schacht, W Kyle Simmons
GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders. Nature medicine (2023)
Jillian T Battista, Daria Piacentino, Melanie L Schwandt, Mary R Lee, Monica L Faulkner, Mehdi Farokhnia, Lorenzo Leggio
Investigating the relationship between early life adversity, inflammation and alcohol use. Addiction biology 28 (5) (2023)
Mehdi Farokhnia, Christopher T Rentsch, Vicky Choung, M Adrienne McGinn, Sophie K Elvig, Eliza A Douglass, Luis A Gonzalez, Jenna E Sanfilippo, Renata Cristina Nunes Marchette, Brendan J Tunstall, David A Fiellin, George F Koob, Amy C Justice, Lorenzo Leggio, Leandro F Vendruscolo
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies. Molecular psychiatry (2022)
Mario Perelló, Suzanne L Dickson, Jeffrey M Zigman, Lorenzo Leggio, null null
Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. Journal of neuroendocrinology 35 (1) (2022)
Lorenzo Leggio, Jessica Leigh Mellinger
Alcohol use disorder in community management of chronic liver diseases. Hepatology (Baltimore, Md.) (2022)
Mario Perelló, Suzanne L Dickson, Jeffrey M Zigman, Lorenzo Leggio, null null
Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. Journal of neuroendocrinology 35 (1) (2022)
Anna E Kirkland, Brittney D Browning, ReJoyce Green, Lorenzo Leggio, Dieter J Meyerhoff, Lindsay M Squeglia
Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies. Molecular psychiatry 27 (8) (2022)
Mehdi Farokhnia, Brittney D Browning, Madeline E Crozier, Hui Sun, Fatemeh Akhlaghi, Lorenzo Leggio
The glucagon-like peptide-1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post-mortem brain study. Addiction biology 27 (5) (2022)
Mario Perelló, Suzanne L Dickson, Jeffrey M Zigman, Lorenzo Leggio, null null
Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. Journal of neuroendocrinology (2022)
Mario Perelló, Suzanne L Dickson, Jeffrey M Zigman, Lorenzo Leggio, null null
Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. Journal of neuroendocrinology 35 (1) (2022)
Sara L Deschaine, Lorenzo Leggio
From "Hunger Hormone" to "It's Complicated": Ghrelin Beyond Feeding Control. Physiology (Bethesda, Md.) 37 (1) (2022)
Zhi-Bing You, Eliot L Gardner, Ewa Galaj, Allamar R Moore, Tristram Buck, Chloe J Jordan, Bree A Humburg, Guo-Hua Bi, Zheng-Xiong Xi, Lorenzo Leggio
Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches. Molecular psychiatry 27 (4) (2022)
Mario Perelló, Suzanne L Dickson, Jeffrey M Zigman, Lorenzo Leggio, null null
Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. Journal of neuroendocrinology 35 (1) (2022)
Kharbanda K Kusum, Mehdi Farokhnia, Sara L Deschaine, Raghav Bhargava, Marcela Rodriguez Flores, Carol A Casey, Anthony Peter Goldstone, Elisabeth Jerlhag, Lorenzo Leggio, Karuna Rasineni
Role of the ghrelin system in alcohol use disorder and alcohol-associated liver disease: A narrative review. Alcoholism, clinical and experimental research (2022)
Vanessa A Palzes, Mehdi Farokhnia, Andrea H Kline-Simon, Joseph Elson, Stacy Sterling, Lorenzo Leggio, Constance Weisner, Felicia W Chi
Effectiveness of spironolactone dispensation in reducing weekly alcohol use: a retrospective high-dimensional propensity score-matched cohort study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (12) (2021)
Roberta Agabio, Lorenzo Leggio
Thiamine administration to all patients with alcohol use disorder: why not? The American journal of drug and alcohol abuse (2021)
Markus Heilig, James Mackillop, Diana Martinez, Jürgen Rehm, Lorenzo Leggio, Louk J M J Vanderschuren
Addiction as a brain disease revised: why it still matters, and the need for consilience. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (10) (2021)
Kirsten C Morley, Christina J Perry, Joshua Watt, Tristan Hurzeler, Lorenzo Leggio, Andrew J Lawrence, Paul Haber
New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies. Expert opinion on pharmacotherapy 22 (10) (2021)
Kimberly Goodyear, Talia R Vasaturo-Kolodner, George A Kenna, Robert M Swift, Lorenzo Leggio, Carolina L Haass-Koffler
Alcohol-related changes in behaviors and characteristics from the baseline to the randomization session for treatment and non-treatment seeking participants with alcohol use disorder. The American journal of drug and alcohol abuse (2021)
Daria Piacentino, Silvia Grant-Beurmann, Carlotta Vizioli, Xiaobai Li, Catherine F Moore, Victor Ruiz-Rodado, Mary R Lee, Paule Valery Joseph, Claire M Fraser, Elise M Weerts, Lorenzo Leggio
Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking. Translational psychiatry 11 (1) (2021)
McKenzie Himelein-Wachowiak, Salvatore Giorgi, Amanda Devoto, Muhammad Mahbubur Rahman, Lyle H Ungar, H Andrew Schwartz, David H Epstein, Lorenzo Leggio, Brenda L Curtis
Bots and Misinformation Spread on Social Media: Implications for COVID-19. Journal of medical Internet research 23 (5) (2021)
Zhi-Bing You, Ewa Galaj, Francisco Alén, Bin Wang, Guo-Hua Bi, Allamar R Moore, Tristram Buck, Madeline Crissman, Sruti Pari, Zheng-Xiong Xi, Lorenzo Leggio, Roy A Wise, Eliot L Gardner
Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 47 (8) (2021)
Lorenzo Leggio, Raye Z Litten
The GABA-B receptor agonist baclofen helps patients with alcohol use disorder: why these findings matter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (13) (2021)
Markus Heilig, James Mackillop, Diana Martinez, Jürgen Rehm, Lorenzo Leggio, Louk J M J Vanderschuren
Response to "Addiction is a social disease: just as tenable as calling it a brain disease". Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (10) (2021)
Lisa A Farinelli, Daria Piacentino, Brittney D Browning, Barbara B Brewer, Lorenzo Leggio
Cardiovascular Consequences of Excessive Alcohol Drinking via Electrocardiogram: A Systematic Review. Journal of addictions nursing 32 (1) (2021)
Bruno Scherrer, Julien Guiraud, Giovanni Addolorato, Henri-Jean Aubin, Andrea de Bejczy, Amine Benyamina, Wim van den Brink, Fabio Caputo, Maurice Dematteis, Anna E Goudriaan, Antoni Gual, Falk Kiefer, Lorenzo Leggio, Otto-Michael Lesch, Icro Maremmani, David J Nutt, François Paille, Pascal Perney, Roch Poulnais, Quentin Raffaillac, Jürgen Rehm, Benjamin Rolland, Nicolas Simon, Bo Söderpalm, Wolfgang H Sommer, Henriette Walter, Rainer Spanagel
Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta-regression analysis to develop an enrichment strategy. Alcoholism, clinical and experimental research 45 (9) (2021)
Sara L Deschaine, Mehdi Farokhnia, Adriana Gregory-Flores, Lia J Zallar, Zhi-Bing You, Hui Sun, Deon M Harvey, Renata C N Marchette, Brendan J Tunstall, Bharath K Mani, Jacob E Moose, Mary R Lee, Eliot Gardner, Fatemeh Akhlaghi, Michael Q Steinman, James L Hougland, Jeffrey M Zigman, George F Koob, Leandro F Vendruscolo, Lorenzo Leggio
A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data. Addiction biology (2021)
Navan N Shah, Melanie L Schwandt, Breanne Hobden, David S Baldwin, Julia M A Sinclair, Roberta Agabio, Lorenzo Leggio
The validity of the state-trait anxiety inventory and the brief scale for anxiety in an inpatient sample with alcohol use disorder. Addiction (Abingdon, England) 116 (11) (2021)
Olli Kärkkäinen, Mehdi Farokhnia, Anton Klåvus, Seppo Auriola, Marko Lehtonen, Sara L Deschaine, Daria Piacentino, Kelly M Abshire, Shelley N Jackson, Lorenzo Leggio
Effect of intravenous ghrelin administration, combined with alcohol, on circulating metabolome in heavy drinking individuals with alcohol use disorder. Alcoholism, clinical and experimental research 45 (11) (2021)
Lara A Ray, Erica N Grodin, Lorenzo Leggio, Anita J Bechtholt, Howard Becker, Sarah W Feldstein Ewing, James David Jentsch, Andrea C King, Barbara J Mason, Stephanie O'Malley, James M MacKillop, Markus Heilig, George F Koob
The future of translational research on alcohol use disorder. Addiction biology 26 (2) (2020)
Carolina L Haass-Koffler, Roberta Perciballi, Zoe E Brown, Mary R Lee, William H Zywiak, Jonathan Kurtis, Robert M Swift, Lorenzo Leggio
Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders. The American journal on addictions 30 (1) (2020)
Yann Ehinger, Khanhky Phamluong, David Darevesky, Melanie Welman, Jeffrey J Moffat, Samuel A Sakhai, Ellanor L Whiteley, Anthony L Berger, Sophie Laguesse, Mehdi Farokhnia, Lorenzo Leggio, Marie Lordkipanidzé, Dorit Ron
Differential correlation of serum BDNF and microRNA content in rats with rapid or late onset of heavy alcohol use. Addiction biology 26 (2) (2020)
Carolina L Haass-Koffler, Daria Piacentino, Xiaobai Li, Victoria M Long, Mary R Lee, Robert M Swift, George A Kenna, Lorenzo Leggio
Differences in Sociodemographic and Alcohol-Related Clinical Characteristics Between Treatment Seekers and Nontreatment Seekers and Their Role in Predicting Outcomes in the COMBINE Study for Alcohol Use Disorder. Alcoholism, clinical and experimental research 44 (10) (2020)
Mary R Lee, Jung H Shin, Sara Deschaine, Allison M Daurio, Bethany L Stangl, Jia Yan, Vijay A Ramchandani, Melanie L Schwandt, Erica N Grodin, Reza Momenan, Nadia S Corral-Frias, Ahmad R Hariri, Ryan Bogdan, Veronica A Alvarez, Lorenzo Leggio
A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans. The American journal of drug and alcohol abuse 46 (2) (2019)
Mehdi Farokhnia, Reza Momenan, Lorenzo Leggio
Commentary on Schmitz et al. (2017): Advancing medication development for addiction-behavioral and neuroimaging outcomes as indirect biomarkers of target engagement. Addiction (Abingdon, England) 112 (10) (2019)
Katie A Witkiewitz, R Z Litten, Lorenzo Leggio
Advances in the science and treatment of alcohol use disorder. Science advances 5 (9) (2019)
Sravani Adusumalli, Rohitash Jamwal, R Scott Obach, Tim F Ryder, Lorenzo Leggio, Fatemeh Akhlaghi
Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach. Drug metabolism and disposition: the biological fate of chemicals 47 (8) (2019)
Allison M Daurio, Sara L Deschaine, Amirhossein Modabbernia, Lorenzo Leggio
Parsing out the role of dopamine D4 receptor gene (DRD4) on alcohol-related phenotypes: A meta-analysis and systematic review. Addiction biology 25 (3) (2019)
Lia J Zallar, Silvia Beurmann, Brendan J Tunstall, Claire M Fraser, George F Koob, Leandro F Vendruscolo, Lorenzo Leggio
Ghrelin receptor deletion reduces binge-like alcohol drinking in rats. Journal of neuroendocrinology 31 (7) (2019)
Raye Z Litten, Daniel E Falk, Megan L Ryan, Joanne Fertig, Lorenzo Leggio
Five Priority Areas for Improving Medications Development for Alcohol Use Disorder and Promoting Their Routine Use in Clinical Practice. Alcoholism, clinical and experimental research 44 (1) (2019)
Daniel E Falk, Megan L Ryan, Joanne B Fertig, Eric G Devine, Ricardo Cruz, E Sherwood Brown, Heather Burns, Ihsan M Salloum, D Jeffrey Newport, John Mendelson, Gantt Galloway, Kyle Kampman, Catherine Brooks, Alan I Green, Mary F Brunette, Richard N Rosenthal, Kelly E Dunn, Eric C Strain, Lara A Ray, Steven Shoptaw, Nassima Ait-Daoud Tiouririne, Erik W Gunderson, Janet Ransom, Charles Scott, Lorenzo Leggio, Steven Caras, Barbara J Mason, Raye Z Litten, null null
Gabapentin Enacarbil Extended-Release for Alcohol Use Disorder: A Randomized, Double-Blind, Placebo-Controlled, Multisite Trial Assessing Efficacy and Safety. Alcoholism, clinical and experimental research 43 (1) (2018)
L J Zallar, B J Tunstall, C T Richie, Y J Zhang, Z B You, E L Gardner, M Heilig, J Pickel, G F Koob, L F Vendruscolo, B K Harvey, Lorenzo Leggio
Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model. International journal of obesity (2005) 43 (2) (2018)
Kirsten C Morley, Andrew J Baillie, Wim Van Den Brink, Kate E Chitty, Kathleen Brady, Sudie E Back, Devanshi Seth, Greg Sutherland, Lorenzo Leggio, Paul S Haber
N-acetyl cysteine in the treatment of alcohol use disorder in patients with liver disease: Rationale for further research. Expert opinion on investigational drugs 27 (8) (2018)
Laurel S Morris, Valerie Voon, Lorenzo Leggio
Stress, Motivation, and the Gut-Brain Axis: A Focus on the Ghrelin System and Alcohol Use Disorder. Alcoholism, clinical and experimental research (2018)
Breanne Hobden, Melanie L Schwandt, Mariko Carey, Mary R Lee, Mehdi Farokhnia, Sofia Bouhlal, Christopher Oldmeadow, Lorenzo Leggio
The Validity of the Montgomery-Asberg Depression Rating Scale in an Inpatient Sample with Alcohol Dependence. Alcoholism, clinical and experimental research 41 (6) (2017)
Allison M Daurio, Sean A Aston, Melanie L Schwandt, Mohammad O Bukhari, Sofia Bouhlal, Mehdi Farokhnia, Mary R Lee, Lorenzo Leggio
Impulsive Personality Traits Mediate the Relationship Between Adult Attention-Deficit/Hyperactivity Symptoms and Alcohol Dependence Severity. Alcoholism, clinical and experimental research 42 (1) (2017)
Christopher W Kahler, Patricia A Cioe, Golfo K Tzilos, Nichea S Spillane, Lorenzo Leggio, Susan E Ramsey, Richard A Brown, Stephanie S O'Malley
A Double-Blind Randomized Placebo-Controlled Trial of Oral Naltrexone for Heavy-Drinking Smokers Seeking Smoking Cessation Treatment. Alcoholism, clinical and experimental research 41 (6) (2017)