Mark D Distefano

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 43

Top Topics

Binding Protein

Top Venues

Bioconjugate chemistry

bioRxiv : the preprint server for biology

Biomacromolecules

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Kiall Francis G Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alexandru M Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Michelle Przedborski, Mark D Distefano
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. bioRxiv : the preprint server for biology (2024)
Yiao Wang, Ozgun Kilic, Lakmal Rozumalski, Mark D Distefano, Carston R Wagner
Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death. Bioconjugate chemistry 35 (5) (2024)
Jiaqian Li, Yiao Wang, Mark D Distefano, Carston R Wagner, William C K Pomerantz
Multivalent Fluorinated Nanorings for On-Cell 19 F NMR. Biomacromolecules 25 (2) (2024)
Kiall Francis G Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alexandru M Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Michelle Przedborski, Mark D Distefano
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. bioRxiv : the preprint server for biology (2024)
Shelby A Auger, Sneha Venkatachalapathy, Kiall Francis G Suazo, Yiao Wang, Alexander W Sarkis, Kaitlyn Bernhagen, Katarzyna Justyna, Jonas V Schaefer, James W Wollack, Andreas Plückthun, Ling Li, Mark D Distefano
Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry. Bioconjugate chemistry (2024)
Garrett L Schey, Emily R Hildebrandt, You Wang, Safwan Diwan, Holly A Passetti, Gavin W Potts, Andrea M Sprague-Getsy, Ethan R Leoni, Taylor S Kuebler, Yuk Yin Sham, James L Hougland, Lorena S Beese, Walter K Schmidt, Mark D Distefano
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase. International journal of molecular sciences 25 (10) (2024)
Shelby A Auger, Sneha Venkatachalapathy, Kiall Francis G Suazo, Yiao Wang, Alexander W Sarkis, Kaitlyn Bernhagen, Katarzyna Justyna, Jonas V Schaefer, James W Wollack, Andreas Plückthun, Ling Li, Mark D Distefano
Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry. Bioconjugate chemistry (2024)
Shelby A Auger, Sneha Venkatachalapathy, Kiall Francis G Suazo, Yiao Wang, Alexander W Sarkis, Kaitlyn Bernhagen, Katarzyna Justyna, Jonas V Schaefer, James W Wollack, Andreas Plückthun, Ling Li, Mark D Distefano
Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry. Bioconjugate chemistry (2024)
Kiall Francis G Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alexandru M Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Michelle Przedborski, Mark D Distefano
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. bioRxiv : the preprint server for biology (2024)
Jiaqian Li, Yiao Wang, Mark D Distefano, Carston R Wagner, William C K Pomerantz
Multivalent Fluorinated Nanorings for On-Cell 19 F NMR. Biomacromolecules (2024)
Jiaqian Li, Yiao Wang, Mark D Distefano, Carston R Wagner, William C K Pomerantz
Multivalent Fluorinated Nanorings for On-Cell 19 F NMR. Biomacromolecules 25 (2) (2024)
Yiao Wang, Ozgun Kilic, Lakmal Rozumalski, Mark D Distefano, Carston R Wagner
Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death. Bioconjugate chemistry (2024)
Garrett L Schey, Emily R Hildebrandt, You Wang, Safwan Diwan, Holly A Passetti, Gavin W Potts, Andrea M Sprague-Getsy, Ethan R Leoni, Taylor S Kuebler, Yuk Yin Sham, James L Hougland, Lorena S Beese, Walter K Schmidt, Mark D Distefano
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase. International journal of molecular sciences 25 (10) (2024)
Yiao Wang, Ozgun Kilic, Lakmal Rozumalski, Mark D Distefano, Carston R Wagner
Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death. Bioconjugate chemistry 35 (5) (2024)
Kiall Francis G Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alexandru M Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Michelle Przedborski, Mark D Distefano
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. bioRxiv : the preprint server for biology (2024)
Kiall Francis G Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alexandru M Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Michelle Przedborski, Mark D Distefano
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. bioRxiv : the preprint server for biology (2024)
Shelby A Auger, Sneha Venkatachalapathy, Kiall Francis G Suazo, Yiao Wang, Alexander W Sarkis, Kaitlyn Bernhagen, Katarzyna Justyna, Jonas V Schaefer, James W Wollack, Andreas Plückthun, Ling Li, Mark D Distefano
Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry. Bioconjugate chemistry 35 (7) (2024)
Kiall Francis G Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alexandru M Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Michelle Przedborski, Mark D Distefano
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. bioRxiv : the preprint server for biology (2024)
Jiaqian Li, Yiao Wang, Mark D Distefano, Carston R Wagner, William C K Pomerantz
Multivalent Fluorinated Nanorings for On-Cell 19 F NMR. Biomacromolecules 25 (2) (2024)
Kiall Francis G Suazo, Jakub Bělíček, Garrett L Schey, Shelby A Auger, Alexandru M Petre, Ling Li, Katarzyna M Błażewska, David Kopečný, Mark D Distefano
Thinking outside the CaaX-box: an unusual reversible prenylation on ALDH9A1. RSC chemical biology 4 (11) (2023)
Anastasiia Petenkova, Shelby A Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To, Jelena Milosevic, Rana Barghout, Abirami Kugadas, Xiaoxiao Lu, Jennifer Geddes-McAlister, Raina Fichorova, David Brian Sykes, Mark D Distefano, Mihaela Gadjeva
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature communications 14 (1) (2023)
Anastasiia Petenkova, Shelby A Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To, Jelena Milosevic, Rana Barghout, Abirami Kugadas, Xiaoxiao Lu, Jennifer Geddes-McAlister, Raina Fichorova, David Brian Sykes, Mark D Distefano, Mihaela Gadjeva
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature communications 14 (1) (2023)
Anastasiia Petenkova, Shelby A Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To, Jelena Milosevic, Rana Barghout, Abirami Kugadas, Xiaoxiao Lu, Jennifer Geddes-McAlister, Raina Fichorova, David Brian Sykes, Mark D Distefano, Mihaela Gadjeva
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities. Nature communications 14 (1) (2023)
Robbins Puthenveetil, Shelby A Auger, Natalia Gómez-Navarro, Mitra Shumsher Rana, Riki Das, Liam Brendan Healy, Kiall Francis G Suazo, Zhen-Dan Shi, Rolf E Swenson, Mark D Distefano, Anirban Banerjee
Orthogonal Enzyme-Substrate Design Strategy for Discovery of Human Protein Palmitoyltransferase Substrates. Journal of the American Chemical Society (2023)
Katarzyna Justyna, Riki Das, Ellen L Lorimer, Jiayue Hu, Jodi S Pedersen, Andrea M Sprague-Getsy, Garrett L Schey, Michelle A Sieburg, Olivia J Koehn, Yen-Chih Wang, Yong Xiang Chen, James L Hougland, Carol L Williams, Mark D Distefano
Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues. Organic letters (2023)
Johannes Morstein, Taysir Bader, Ariana L Cardillo, Julian Schackmann, Sudhat Ashok, James L Hougland, Christine A Hrycyna, Dirk H Trauner, Mark D Distefano
Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation. ACS chemical biology 17 (10) (2022)
Yi Zhang, Yiao Wang, Safak Uslu, Sneha Venkatachalapathy, Mohammad Rashidian, Jonas V Schaefer, Andreas Plückthun, Mark D Distefano
Enzymatic Construction of DARPin-Based Targeted Delivery Systems Using Protein Farnesyltransferase and a Capture and Release Strategy. International journal of molecular sciences 23 (19) (2022)
Yiao Wang, Carston R Wagner, Mark D Distefano
Manipulating Cell Fates with Protein Conjugates. Bioconjugate chemistry 33 (10) (2022)
Yiao Wang, Lakmal Rozumalski, Ozgun Kilic, Caitlin Lichtenfels, Jacob Petersberg, Mark D Distefano, Carston R Wagner
Engineering Biomimetic Trogocytosis with Farnesylated Chemically Self-Assembled Nanorings. Biomacromolecules (2022)
You Wang, Feng Xu, Connie B Nichols, Yuqian Shi, Homme W Hellinga, J Andrew Alspaugh, Mark D Distefano, Lorena S Beese
Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase. Journal of medicinal chemistry 65 (20) (2022)
Zoë A Maxwell, Kiall Francis G Suazo, Heather M G Brown, Mark D Distefano, Edgar A Arriaga
Combining Isoprenoid Probes with Antibody Markers for Mass Cytometric Analysis of Prenylation in Single Cells. Analytical chemistry 94 (33) (2022)
Angela Jeong, Shelby A Auger, Sanjay Maity, Kristina Fredriksen, Rui Zhong, Ling Li, Mark D Distefano
In Vivo Prenylomic Profiling in the Brain of a Transgenic Mouse Model of Alzheimer's Disease Reveals Increased Prenylation of a Key Set of Proteins. ACS chemical biology 17 (10) (2022)
Aleksi Isomursu, Keun-Young Park, Jay Hou, Bo Cheng, Mathilde Mathieu, Ghaidan A Shamsan, Benjamin Fuller, Jesse Kasim, M Mohsen Mahmoodi, Tian Jian Lu, Guy M Genin, Feng Xu, Min Lin, Mark D Distefano, Johanna Ivaska, David J Odde
Directed cell migration towards softer environments. Nature materials 21 (9) (2022)
Kiall Francis G Suazo, Angela Jeong, Mina Ahmadi, Caroline Brown, Wenhui Qu, Ling Li, Mark D Distefano
Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells. Scientific reports 11 (1) (2021)
Alicia E Mangubat-Medina, Hallie O Trial, Reyner D Vargas, Mekedlawit T Setegne, Taysir Bader, Mark D Distefano, Zachary T Ball
Red-shifted backbone N-H photocaging agents. Organic & biomolecular chemistry 18 (27) (2021)
Kiall Francis G Suazo, Keun-Young Park, Mark D Distefano
A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications. Chemical reviews 121 (12) (2021)
Matthew D Hammers, Michael H Hodny, Taysir K Bader, M Mohsen Mahmoodi, Sifei Fang, Alexander D Fenton, Kadiro Nurie, Hallie O Trial, Feng Xu, Andrew T Healy, Zachary T Ball, David A Blank, Mark D Distefano
Two-photon uncaging of bioactive thiols in live cells at wavelengths above 800 nm. Organic & biomolecular chemistry 19 (10) (2021)
Garrett L Schey, Peter H Buttery, Emily R Hildebrandt, Sadie X Novak, Walter K Schmidt, James L Hougland, Mark D Distefano
MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase. International journal of molecular sciences 22 (21) (2021)
Wenhui Qu, Kiall Francis G Suazo, Wen-Feng Liu, Shaowu Cheng, Angela Jeong, David Hottman, Li-Lian Yuan, Mark D Distefano, Ling Li
Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function. Molecular neurobiology 58 (3) (2020)
Yiao Wang, Ozgun Kilic, Clifford M Csizmar, Sudhat Ashok, James L Hougland, Mark D Distefano, Carston R Wagner
Engineering reversible cell-cell interactions using enzymatically lipidated chemically self-assembled nanorings. Chemical science 12 (1) (2020)
Ozgun Kilic, Marcos Romário Matos de Souza, Abdulaziz A Almotlak, Yiao Wang, Jill M Siegfried, Mark D Distefano, Carston R Wagner
Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T Cell-Mediated Antitumor Responses and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression. Journal of medicinal chemistry 63 (18) (2020)
Taysir K Bader, Feng Xu, Michael H Hodny, David A Blank, Mark D Distefano
Methoxy-Substituted Nitrodibenzofuran-Based Protecting Group with an Improved Two-Photon Action Cross-Section for Thiol Protection in Solid Phase Peptide Synthesis. The Journal of organic chemistry 85 (3) (2020)
Veronica Diaz-Rodriguez, Erh-Ting Hsu, Elena Ganusova, Elena R Werst, Jeffrey M Becker, Christine A Hrycyna, Mark D Distefano
a-Factor Analogues Containing Alkyne- and Azide-Functionalized Isoprenoids Are Efficiently Enzymatically Processed and Retain Wild-Type Bioactivity. Bioconjugate chemistry 29 (2) (2017)