Jan Jakubík (Jan Jakubik)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 13

Top Venues

International journal of molecular sciences

British journal of pharmacology

Expert opinion on drug discovery

Scientific reports

Institute of Physiology CAS

First Faculty of Medicine, Charles University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute of Physiology CAS May 1o 2001

Czechia

researcher/scientist :: Neurochemistry

Education History

First Faculty of Medicine, Charles University Oct 1o 1993 - Jun 30o 1997

Czechia

PHD

Publications

Ewa Szczurowska, Eszter Szánti-Pintér, Alena Randáková, Jan Jakubík, Eva Kudova
Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids. International journal of molecular sciences 23 (21) (2022)
Ewa Szczurowska, Eszter Szánti-Pintér, Nikolai Chetverikov, Alena Randáková, Eva Kudova, Jan Jakubík
Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids. International journal of molecular sciences 24 (1) (2022)
Ewa Szczurowska, Eszter Szánti-Pintér, Nikolai Chetverikov, Alena Randáková, Eva Kudova, Jan Jakubík
Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids. International journal of molecular sciences 24 (1) (2022)
Ewa Szczurowska, Eszter Szánti-Pintér, Nikolai Chetverikov, Alena Randáková, Eva Kudova, Jan Jakubík
Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids. International journal of molecular sciences 24 (1) (2022)
Jan Jakubík, Alena Randáková
Insights into the operational model of agonism of receptor dimers. Expert opinion on drug discovery (2022)
Jan Jakubík, Esam E El-Fakahany
Allosteric Modulation of GPCRs of Class A by Cholesterol. International journal of molecular sciences 22 (4) (2021)
Marek Staszewski, Dominik Nelic, Jakub Jończyk, Mariam Dubiel, Annika Frank, Holger Stark, Marek Bajda, Jan Jakubík, Krzysztof Walczyński
Guanidine Derivatives: How Simple Structural Modification of Histamine H3R Antagonists Has Led to the Discovery of Potent Muscarinic M2R/M4R Antagonists. ACS chemical neuroscience 12 (13) (2021)
Alena Randáková, Dominik Nelic, Martina Hochmalová, Pavel Zimčík, Mutale Jane Mulenga, John Boulos, Jan Jakubík
Fusion with Promiscuous Gα16 Subunit Reveals Signaling Bias at Muscarinic Receptors. International journal of molecular sciences 22 (18) (2021)
Alena Randáková, Dominik Nelic, Dana Ungerová, Peter Nwokoye, Qiwen Su, Vladimír Doležal, Esam E El-Fakahany, John F Boulos, Jan Jakubík
Novel M2 -selective, Gi -biased agonists of muscarinic acetylcholine receptors. British journal of pharmacology 177 (9) (2020)
Alena Randáková, Dominik Nelic, Vladimír Doležal, Esam E El-Fakahany, John Boulos, Jan Jakubík
Agonist-Specific Conformations of the M2 Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics. Journal of chemical information and modeling 60 (4) (2020)
Jan Jakubík, Alena Randáková, Vladimír Rudajev, Pavel Zimčík, Esam E El-Fakahany, Vladimír Doležal
Applications and limitations of fitting of the operational model to determine relative efficacies of agonists. Scientific reports 9 (1) (2019)
Jan Jakubík, Alena Randáková, Esam E El-Fakahany, Vladimír Doležal
Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators. PloS one 14 (3) (2019)
Alena Randáková, Vladimír Rudajev, Vladimír Doležal, John F Boulos, Jan Jakubík
Novel long-acting antagonists of muscarinic ACh receptors. British journal of pharmacology 175 (10) (2018)

Jan Jakubík.css-eqlu8i{font-size:small;padding-left:4px;} (Jan Jakubik)

Publication Activity (10 Years)

Top Topics

Top Venues

Jan Jakubík (Jan Jakubik)