Jeffrey D Kearns

Publication Activity (10 Years)

Years Active: 2021-2023
Publications (10 Years): 9

Top Topics

Immune Response

Vascular Endothelial Growth Factor

Diabetic Retinopathy

Age Related Macular Degeneration

Top Venues

Science translational medicine

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Anette C Karle, Matthias B Wrobel, Stephan Koepke, Michael Gutknecht, Sascha Gottlieb, Brigitte Christen, Tina Rubic-Schneider, Ingrid Pruimboom-Brees, Xavier Charles Leber, Meike Scharenberg, Benjamin Maciejewski, Oliver C Turner, Chandrassegar Saravanan, François Huet, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Jeffrey D Kearns, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees
Anti-brolucizumab immune response as one prerequisite for rare retinal vasculitis/retinal vascular occlusion adverse events. Science translational medicine 15 (681) (2023)
Jeffrey D Kearns, Paul Wassmann, Ufuk Olgac, Marie Fichter, Brigitte Christen, Tina Rubic-Schneider, Stephan Koepke, Benjamin Cochin de Billy, David Ledieu, Cedric Andre, Stuart Hawtin, Benoit Fischer, Francesca Moretti, Christian Hug, Alexander Bepperling, Barbara Brannetti, Celia Mendez-Garcia, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees, Anette C Karle
A root cause analysis to identify the mechanistic drivers of immunogenicity against the anti-VEGF biotherapeutic brolucizumab. Science translational medicine 15 (681) (2023)
Anette C Karle, Matthias B Wrobel, Stephan Koepke, Michael Gutknecht, Sascha Gottlieb, Brigitte Christen, Tina Rubic-Schneider, Ingrid Pruimboom-Brees, Xavier Charles Leber, Meike Scharenberg, Benjamin Maciejewski, Oliver C Turner, Chandrassegar Saravanan, François Huet, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Jeffrey D Kearns, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees
Anti-brolucizumab immune response as one prerequisite for rare retinal vasculitis/retinal vascular occlusion adverse events. Science translational medicine 15 (681) (2023)
Jeffrey D Kearns, Paul Wassmann, Ufuk Olgac, Marie Fichter, Brigitte Christen, Tina Rubic-Schneider, Stephan Koepke, Benjamin Cochin de Billy, David Ledieu, Cedric Andre, Stuart Hawtin, Benoit Fischer, Francesca Moretti, Christian Hug, Alexander Bepperling, Barbara Brannetti, Celia Mendez-Garcia, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees, Anette C Karle
A root cause analysis to identify the mechanistic drivers of immunogenicity against the anti-VEGF biotherapeutic brolucizumab. Science translational medicine 15 (681) (2023)
Jeffrey D Kearns, Paul Wassmann, Ufuk Olgac, Marie Fichter, Brigitte Christen, Tina Rubic-Schneider, Stephan Koepke, Benjamin Cochin de Billy, David Ledieu, Cedric Andre, Stuart Hawtin, Benoit Fischer, Francesca Moretti, Christian Hug, Alexander Bepperling, Barbara Brannetti, Celia Mendez-Garcia, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees, Anette C Karle
A root cause analysis to identify the mechanistic drivers of immunogenicity against the anti-VEGF biotherapeutic brolucizumab. Science translational medicine 15 (681) (2023)
Anette C Karle, Matthias B Wrobel, Stephan Koepke, Michael Gutknecht, Sascha Gottlieb, Brigitte Christen, Tina Rubic-Schneider, Ingrid Pruimboom-Brees, Xavier Charles Leber, Meike Scharenberg, Benjamin Maciejewski, Oliver C Turner, Chandrassegar Saravanan, François Huet, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Jeffrey D Kearns, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees
Anti-brolucizumab immune response as one prerequisite for rare retinal vasculitis/retinal vascular occlusion adverse events. Science translational medicine 15 (681) (2023)
Anette C Karle, Matthias B Wrobel, Stephan Koepke, Michael Gutknecht, Sascha Gottlieb, Brigitte Christen, Tina Rubic-Schneider, Ingrid Pruimboom-Brees, Xavier Charles Leber, Meike Scharenberg, Benjamin Maciejewski, Oliver C Turner, Chandrassegar Saravanan, François Huet, Amanda Littlewood-Evans, Andreas Clemens, Cynthia L Grosskreutz, Jeffrey D Kearns, Pawan Mehan, Robert L Schmouder, Vito Sasseville, Dominique Brees
Anti-brolucizumab immune response as one prerequisite for rare retinal vasculitis/retinal vascular occlusion adverse events. Science translational medicine 15 (681) (2023)
Andreas Weiss, Edwige Lorthiois, Louise Barys, Kim S Beyer, Claudio Bomio, Heather Burks, Xueying Chen, Xiaoming Cui, Ruben de Kanter, Lekshmi Dharmarajan, Carmine Fedele, Marc Gerspacher, Daniel Alexander Guthy, Victoria Head, Ashley Jaeger, Eloísa Jiménez Núñez, Jeffrey D Kearns, Catherine Leblanc, Sauveur-Michel Maira, Jason Murphy, Helen Oakman, Nils Ostermann, Johannes Ottl, Pascal Rigollier, Danielle Roman, Christian Schnell, Richard Sedrani, Toshio Shimizu, Rowan Stringer, Andrea Vaupel, Johannes Voshol, Peter Wessels, Toni Widmer, Rainer Wilcken, Kun Xu, Frederic Zecri, Anna F Farago, Simona Cotesta, Saskia M Brachmann
Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C. Cancer discovery 12 (6) (2022)
E Josue Ruiz, Adan Pinto-Fernandez, Andrew P Turnbull, Linxiang Lan, Thomas M Charlton, Hannah C Scott, Andreas Damianou, George Vere, Eva M Riising, Clive Da Costa, Wojciech W Krajewski, David Guerin, Jeffrey D Kearns, Stephanos Ioannidis, Marie Katz, Crystal McKinnon, Jonathan O'Connell, Natalia Moncaut, Ian Rosewell, Emma Nye, Neil Jones, Claire Heride, Malte Gersch, Min Wu, Christopher J Dinsmore, Tim R Hammonds, Sunkyu Kim, David Komander, Sylvie Urbe, Michael J Clague, Benedikt Mathias Kessler, Axel Behrens
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma. eLife 10 (2021)