Jeroen Kool

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 53

Top Topics

Liquid Chromatography

Escherichia Coli

Mass Spectrometry

Top Venues

Nature communications

Analytical chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Dimoetsha J C Weekers, Luis Lago Alonso, Anniek X Verstegen, Julien Slagboom, Jeroen Kool
Qualitative Profiling of Venom Toxins in the Venoms of Several Bothrops Species Using High-Throughput Venomics and Coagulation Bioassaying. Toxins 16 (7) (2024)
Haifeng Xu, Jesse Mastenbroek, Natascha T B Krikke, Susan El-Asal, Rama Mutlaq, Nicholas R Casewell, Julien Slagboom, Jeroen Kool
Nanofractionation Analytics for Comparing MALDI-MS and ESI-MS Data of Viperidae Snake Venom Toxins. Toxins 16 (8) (2024)
Luis Lago Alonso, Jory van Thiel, Julien Slagboom, Nathan Dunstan, Cassandra M Modahl, Timothy N W Jackson, Saer Samanipour, Jeroen Kool
Studying Venom Toxin Variation Using Accurate Masses from Liquid Chromatography-Mass Spectrometry Coupled with Bioinformatic Tools. Toxins 16 (4) (2024)
Luis Lago Alonso, Jory van Thiel, Julien Slagboom, Nathan Dunstan, Cassandra M Modahl, Timothy N W Jackson, Saer Samanipour, Jeroen Kool
Studying Venom Toxin Variation Using Accurate Masses from Liquid Chromatography-Mass Spectrometry Coupled with Bioinformatic Tools. Toxins 16 (4) (2024)
Haifeng Xu, Jesse Mastenbroek, Natascha T B Krikke, Susan El-Asal, Rama Mutlaq, Nicholas R Casewell, Julien Slagboom, Jeroen Kool
Nanofractionation Analytics for Comparing MALDI-MS and ESI-MS Data of Viperidae Snake Venom Toxins. Toxins 16 (8) (2024)
Dimoetsha J C Weekers, Luis Lago Alonso, Anniek X Verstegen, Julien Slagboom, Jeroen Kool
Qualitative Profiling of Venom Toxins in the Venoms of Several Bothrops Species Using High-Throughput Venomics and Coagulation Bioassaying. Toxins 16 (7) (2024)
Luis Lago Alonso, Jory van Thiel, Julien Slagboom, Nathan Dunstan, Cassandra M Modahl, Timothy N W Jackson, Saer Samanipour, Jeroen Kool
Studying Venom Toxin Variation Using Accurate Masses from Liquid Chromatography-Mass Spectrometry Coupled with Bioinformatic Tools. Toxins 16 (4) (2024)
Luis Lago Alonso, Jory van Thiel, Julien Slagboom, Nathan Dunstan, Cassandra M Modahl, Timothy N W Jackson, Saer Samanipour, Jeroen Kool
Studying Venom Toxin Variation Using Accurate Masses from Liquid Chromatography-Mass Spectrometry Coupled with Bioinformatic Tools. Toxins 16 (4) (2024)
Mátyás A Bittenbinder, Jory van Thiel, Fernanda C Cardoso, Nicholas R Casewell, José María Gutiérrez, Jeroen Kool, Freek J Vonk
Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies. Communications biology 7 (1) (2024)
Mátyás A Bittenbinder, Jory van Thiel, Fernanda C Cardoso, Nicholas R Casewell, José María Gutiérrez, Jeroen Kool, Freek J Vonk
Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies. Communications biology 7 (1) (2024)
Mieke Nys, Eleftherios Zarkadas, Marijke Brams, Aujan Mehregan, Kumiko Kambara, Jeroen Kool, Nicholas R Casewell, Daniel Bertrand, John E Baenziger, Hugues Nury, Chris Ulens
Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors. Nature communications 15 (1) (2024)
Dimoetsha J C Weekers, Luis Lago Alonso, Anniek X Verstegen, Julien Slagboom, Jeroen Kool
Qualitative Profiling of Venom Toxins in the Venoms of Several Bothrops Species Using High-Throughput Venomics and Coagulation Bioassaying. Toxins 16 (7) (2024)
Haifeng Xu, Jesse Mastenbroek, Natascha T B Krikke, Susan El-Asal, Rama Mutlaq, Nicholas R Casewell, Julien Slagboom, Jeroen Kool
Nanofractionation Analytics for Comparing MALDI-MS and ESI-MS Data of Viperidae Snake Venom Toxins. Toxins 16 (8) (2024)
Mieke Nys, Eleftherios Zarkadas, Marijke Brams, Aujan Mehregan, Kumiko Kambara, Jeroen Kool, Nicholas R Casewell, Daniel Bertrand, John E Baenziger, Hugues Nury, Chris Ulens
Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors. Nature communications 15 (1) (2024)
Steven R Hall, Sean A Rasmussen, Edouard Crittenden, Charlotte A Dawson, Keirah E Bartlett, Adam P Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R Casewell
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms. Nature communications 14 (1) (2023)
Mátyás A Bittenbinder, Nick D Bergkamp, Julien Slagboom, Jan Paul M Bebelman, Nicholas R Casewell, Marco H Siderius, Martine J Smit, Jeroen Kool, Freek J Vonk
Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled Substrates. Biology 12 (6) (2023)
Luis Lago Alonso, Julien Slagboom, Nicholas R Casewell, Saer Samanipour, Jeroen Kool
Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools. Toxins 15 (2) (2023)
Steven R Hall, Sean A Rasmussen, Edouard Crittenden, Charlotte A Dawson, Keirah E Bartlett, Adam P Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R Casewell
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms. Nature communications 14 (1) (2023)
Steven R Hall, Sean A Rasmussen, Edouard Crittenden, Charlotte A Dawson, Keirah E Bartlett, Adam P Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R Casewell
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms. Nature communications 14 (1) (2023)
Jory van Thiel, Luis L Alonso, Julien Slagboom, Nathan Dunstan, Roel M Wouters, Cassandra M Modahl, Freek J Vonk, Timothy N W Jackson, Jeroen Kool
Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans ( Oxyuranus spp.) and Brown Snakes ( Pseudonaja spp.). Toxins 15 (1) (2023)
Jory van Thiel, Luis L Alonso, Julien Slagboom, Nathan Dunstan, Roel M Wouters, Cassandra M Modahl, Freek J Vonk, Timothy N W Jackson, Jeroen Kool
Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans ( Oxyuranus spp.) and Brown Snakes ( Pseudonaja spp.). Toxins 15 (1) (2023)
Julien Slagboom, Rico J E Derks, Raya Sadighi, Govert W Somsen, Chris Ulens, Nicholas R Casewell, Jeroen Kool
High-Throughput Venomics. Journal of proteome research (2023)
Luis Lago Alonso, Julien Slagboom, Nicholas R Casewell, Saer Samanipour, Jeroen Kool
Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools. Toxins 15 (2) (2023)
Eric Wachtel, Matyas A Bittenbinder, Bas van de Velde, Julien Slagboom, Axel de Monts de Savasse, Luis Lago Alonso, Nicholas R Casewell, Freek J Vonk, Jeroen Kool
Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins. Toxins 15 (4) (2023)
Matyas A Bittenbinder, Liliana Capinha, Daniel Da Costa Pereira, Julien Slagboom, Bas van de Velde, Nicholas R Casewell, Paul Jennings, Jeroen Kool, Freek J Vonk
Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms. PLoS neglected tropical diseases 17 (8) (2023)
Luis Lago Alonso, Julien Slagboom, Nicholas R Casewell, Saer Samanipour, Jeroen Kool
Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools. Toxins 15 (2) (2023)
Jory van Thiel, Luis L Alonso, Julien Slagboom, Nathan Dunstan, Roel M Wouters, Cassandra M Modahl, Freek J Vonk, Timothy N W Jackson, Jeroen Kool
Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans ( Oxyuranus spp.) and Brown Snakes ( Pseudonaja spp.). Toxins 15 (1) (2023)
Luis Lago Alonso, Julien Slagboom, Nicholas R Casewell, Saer Samanipour, Jeroen Kool
Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools. Toxins 15 (2) (2023)
Mátyás A Bittenbinder, Nick D Bergkamp, Julien Slagboom, Jan Paul M Bebelman, Nicholas R Casewell, Marco H Siderius, Martine J Smit, Jeroen Kool, Freek J Vonk
Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled Substrates. Biology 12 (6) (2023)
Luis Lago Alonso, Julien Slagboom, Nicholas R Casewell, Saer Samanipour, Jeroen Kool
Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools. Toxins 15 (2) (2023)
Giulia Palermo, Wietse M Schouten, Luis Lago Alonso, Chris Ulens, Jeroen Kool, Julien Slagboom
Acetylcholine-Binding Protein Affinity Profiling of Neurotoxins in Snake Venoms with Parallel Toxin Identification. International journal of molecular sciences 24 (23) (2023)
Eric Wachtel, Matyas A Bittenbinder, Bas van de Velde, Julien Slagboom, Axel de Monts de Savasse, Luis Lago Alonso, Nicholas R Casewell, Freek J Vonk, Jeroen Kool
Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins. Toxins 15 (4) (2023)
Steven R Hall, Sean A Rasmussen, Edouard Crittenden, Charlotte A Dawson, Keirah E Bartlett, Adam P Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R Casewell
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms. Nature communications 14 (1) (2023)
Jory van Thiel, Luis L Alonso, Julien Slagboom, Nathan Dunstan, Roel M Wouters, Cassandra M Modahl, Freek J Vonk, Timothy N W Jackson, Jeroen Kool
Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans ( Oxyuranus spp.) and Brown Snakes ( Pseudonaja spp.). Toxins 15 (1) (2023)
Eric Wachtel, Matyas A Bittenbinder, Bas van de Velde, Julien Slagboom, Axel de Monts de Savasse, Luis Lago Alonso, Nicholas R Casewell, Freek J Vonk, Jeroen Kool
Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins. Toxins 15 (4) (2023)
Eric Wachtel, Matyas A Bittenbinder, Bas van de Velde, Julien Slagboom, Axel de Monts de Savasse, Luis Lago Alonso, Nicholas R Casewell, Freek J Vonk, Jeroen Kool
Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins. Toxins 15 (4) (2023)
Steven R Hall, Sean A Rasmussen, Edouard Crittenden, Charlotte A Dawson, Keirah E Bartlett, Adam P Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R Casewell
Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms. Nature communications 14 (1) (2023)
Eric Wachtel, Matyas A Bittenbinder, Bas van de Velde, Julien Slagboom, Axel de Monts de Savasse, Luis Lago Alonso, Nicholas R Casewell, Freek J Vonk, Jeroen Kool
Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins. Toxins 15 (4) (2023)
Sedef Terzioglu, Mátyás A Bittenbinder, Julien Slagboom, Bas van de Velde, Nicholas R Casewell, Jeroen Kool
Analytical Size Exclusion Chromatography Coupled with Mass Spectrometry in Parallel with High-Throughput Venomics and Bioassaying for Venom Profiling. Toxins 15 (9) (2023)
Björn Marcus von Reumont, Gregor Anderluh, Agostinho Antunes, Naira Ayvazyan, Dimitris Beis, Figen Caliskan, Ana Crnković, Maik Damm, Sebastien Dutertre, Lars Ellgaard, Goran Gajski, Hannah German, Beata Halassy, Benjamin-Florian Hempel, Tim Hucho, Naşit Iğci, Maria P Ikonomopoulou, Kuntal Pal, Maria I Klapa, Ivan Koludarov, Jeroen Kool, Tim Lüddecke, Riadh Ben Mansour, Maria Vittoria Modica, Yehu Moran, Ayse Nalbantsoy, María Eugenia Pachón Ibáñez, Alexios Panagiotopoulos, Eitan Reuveny, Javier Sánchez Céspedes, Andy Sombke, Joachim M Surm, Eivind A B Undheim, Aida Verdes, Giulia Zancolli
Modern venomics-Current insights, novel methods, and future perspectives in biological and applied animal venom research. GigaScience 11 (2022)
Arif Arrahman, Taline D Kazandjian, Kristina B M Still, Julien Slagboom, Govert W Somsen, Freek J Vonk, Nicholas R Casewell, Jeroen Kool
A Combined Bioassay and Nanofractionation Approach to Investigate the Anticoagulant Toxins of Mamba and Cobra Venoms and Their Inhibition by Varespladib. Toxins 14 (11) (2022)
Jingyi Jian, Jiaming Yuan, Yu Fan, Jincai Wang, Tingting Zhang, Jeroen Kool, Zhengjin Jiang
High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening. Molecules (Basel, Switzerland) 27 (20) (2022)
Mieke Nys, Eleftherios Zarkadas, Marijke Brams, Aujan Mehregan, Kumiko Kambara, Jeroen Kool, Nicholas R Casewell, Daniel Bertrand, John E Baenziger, Hugues Nury, Chris Ulens
The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors. Nature communications 13 (1) (2022)
Taline D Kazandjian, Arif Arrahman, Kristina B M Still, Govert W Somsen, Freek J Vonk, Nicholas R Casewell, Mark C Wilkinson, Jeroen Kool
Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib. Toxins 13 (5) (2021)
Louise M van Mourik, Elwin Janssen, Robin Breeuwer, Willem Jonker, Jacco Koekkoek, Arif Arrahman, Jeroen Kool, Pim E G Leonards
Combining High-Resolution Gas Chromatographic Continuous Fraction Collection with Nuclear Magnetic Resonance Spectroscopy: Possibilities of Analyzing a Whole GC Chromatogram. Analytical chemistry 93 (15) (2021)
Freek J Vonk, Mátyás A Bittenbinder, Harald M I Kerkkamp, Dwin G B Grashof, John Patrick Archer, Sandra Afonso, Michael K Richardson, Jeroen Kool, Arie van der Meijden
A non-lethal method for studying scorpion venom gland transcriptomes, with a review of potentially suitable taxa to which it can be applied. PloS one 16 (11) (2021)
Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth, Jaffer Alsolaiss, Edouard Crittenden, Charlotte A Dawson, Rowan Softley, Keirah E Bartlett, Robert A Harrison, Jeroen Kool, Nicholas R Casewell
Author Correction: A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite. Nature communications 12 (1) (2021)
Chunfang Xie, Laura-Oana Albulescu, Kristina B M Still, Julien Slagboom, Yumei Zhao, Zhengjin Jiang, Govert W Somsen, Freek J Vonk, Nicholas R Casewell, Jeroen Kool
Varespladib Inhibits the Phospholipase A2 and Coagulopathic Activities of Venom Components from Hemotoxic Snakes. Biomedicines 8 (6) (2020)
Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth, Jaffer Alsolaiss, Edouard Crittenden, Charlotte A Dawson, Rowan Softley, Keirah E Bartlett, Robert A Harrison, Jeroen Kool, Nicholas R Casewell
A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite. Nature communications 11 (1) (2020)
Julien Slagboom, Marija Mladić, Chunfang Xie, Taline D Kazandjian, Freek Vonk, Govert W Somsen, Nicholas R Casewell, Jeroen Kool
High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches. PLoS neglected tropical diseases 14 (4) (2020)
Chunfang Xie, Laura-Oana Albulescu, Mátyás A Bittenbinder, Govert W Somsen, Freek J Vonk, Nicholas R Casewell, Jeroen Kool
Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins. Biomedicines 8 (9) (2020)
Teemu Suutari, Sabrina N Rahman, Henry F Vischer, Dick van Iperen, Arto Merivaara, Marjo Yliperttula, Rob Leurs, Jeroen Kool, Tapani Viitala
Label-Free Analysis with Multiple Parameters Separates G Protein-Coupled Receptor Signaling Pathways. Analytical chemistry 92 (21) (2020)
Barbara M Zietek, Kristina B M Still, Kevin Jaschusch, Ben Bruyneel, Freek Ariese, Tinco J F Brouwer, Matthijs Luger, Rob J Limburg, Joost C Rosier, Dick J V Iperen, Nicholas R Casewell, Govert W Somsen, Jeroen Kool
Bioactivity Profiling of Small-Volume Samples by Nano Liquid Chromatography Coupled to Microarray Bioassaying Using High-Resolution Fractionation. Analytical chemistry 91 (16) (2019)