Jia Chen

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 11

Top Venues

Nature biotechnology

Cell research

Nature communications

MedComm

ShanghaiTech University

Shanghai Institute of Biochemistry and Cell Biology, CAS (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

ShanghaiTech University Oct 10 2019

China

Associate Professor (with Tenure) :: School of Life Science and Technology

ShanghaiTech University Nov 01 2014 - Oct 09 2019

China

Assistant Professor :: School of Life Science and Technology

National Institute of Diabetes and Digestive and Kidney Diseases Jul 01 2009 - Jun 20 2014

United States

Postdoctoral Fellow

Education History

Shanghai Institute of Biochemistry and Cell Biology, CAS Sep 01 2002 - Apr 02 2009

China

PHD

Nankai University Sep 01 1998 - Jun 30 2002

China

BSC :: Biochemistry and Molecular Biology

Publications

Jin-Soo Kim, Jia Chen
Base editing of organellar DNA with programmable deaminases. Nature reviews. Molecular cell biology (2023)
Wenyan Han, Bao-Qing Gao, Junjie Zhu, Zongxing He, Jianfeng Li, Li Yang, Jia Chen
Design and application of the transformer base editor in mammalian cells and mice. Nature protocols (2023)
Wenwen Zhao, Jifang Li, Xiao Wang, Wei Xu, Bao-Qing Gao, Jiangchao Xiang, Yaofeng Hou, Wei Liu, Jing Wu, Qilian Qi, Jia Wei, Xiaoyu Yang, Lu Lu, Li Yang, Jia Chen, Bei Yang
Prime editor-mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS-CoV-2 variants. MedComm 4 (5) (2023)
Xiaosa Li, Lina Zhou, Bao-Qing Gao, Guangye Li, Xiao Wang, Ying Wang, Jia Wei, Wenyan Han, Zixian Wang, Jifang Li, Runze Gao, Junjie Zhu, Wenchao Xu, Jing Wu, Bei Yang, Xiaodong Sun, Li Yang, Jia Chen
Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure. Nature communications 13 (1) (2022)
Lijie Wang, Wei Xue, Hongxia Zhang, Runze Gao, Houyuan Qiu, Jia Wei, Lina Zhou, Yun-Ni Lei, Xiaocheng Wu, Xiao Li, Chengfang Liu, Jing Wu, Qiubing Chen, Hanhui Ma, Xing-Xu Huang, Cheguo Cai, Ying Zhang, Bei Yang, Hao Yin, Li Yang, Jia Chen
Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations. Nature cell biology 23 (5) (2021)
Jianan Li, Zhen Liu, Shisheng Huang, Xiao Wang, Guanglei Li, Yuting Xu, Wenxia Yu, Shanshan Chen, Yu Zhang, Hanhui Ma, Zunfu Ke, Jia Chen, Qiang Sun, Xingxu Huang
Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome. Cell research 29 (2) (2019)
Xiaosa Li, Ying Wang, Yajing Liu, Bei Yang, Xiao Wang, Jia Wei, Zongyang Lu, Yuxi Zhang, Jing Wu, Xingxu Huang, Li Yang, Jia Chen
Base editing with a Cpf1-cytidine deaminase fusion. Nature biotechnology 36 (4) (2018)
Wen Jiang, Songjie Feng, Shisheng Huang, Wenxia Yu, Guanglei Li, Guang Yang, Yajing Liu, Yu Zhang, Lei Zhang, Yu Hou, Jia Chen, Jieping Chen, Xingxu Huang
BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity. Cell research 28 (8) (2018)
Zhen Liu, Zongyang Lu, Guang Yang, Shisheng Huang, Guanglei Li, Songjie Feng, Yajing Liu, Jianan Li, Wenxia Yu, Yu Zhang, Jia Chen, Qiang Sun, Xingxu Huang
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing. Nature communications 9 (1) (2018)
Xiao Wang, Jianan Li, Ying Wang, Bei Yang, Jia Wei, Jing Wu, Ruixuan Wang, Xingxu Huang, Jia Chen, Li Yang
Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion. Nature biotechnology 36 (10) (2018)
Liqun Lei, Hongquan Chen, Wei Xue, Bei Yang, Bian Hu, Jia Wei, Lijie Wang, Yiqiang Cui, Wei Li, Jianying Wang, Lei Yan, Wanjing Shang, Jimin Gao, Jiahao Sha, Min Zhuang, Xingxu Huang, Bin Shen, Li Yang, Jia Chen
APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks. Nature structural & molecular biology 25 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jia Chen