Jian Xu

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 25

Top Topics

Transcription Factor

Embryonic Stem Cells

Dna Damage Response

Top Venues

Cellular and molecular life sciences : CMLS

Nature communications

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Junhua Lyu, Jian Xu
Context matters: role of ATF4 in hematopoiesis. Blood 144 (7) (2024)
Michael Lee, Syed Farhan Ahmad, Jian Xu
Regulation and function of transposable elements in cancer genomes. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Michael Lee, Syed Farhan Ahmad, Jian Xu
Regulation and function of transposable elements in cancer genomes. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Michael Lee, Syed Farhan Ahmad, Jian Xu
Regulation and function of transposable elements in cancer genomes. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Michael Lee, Syed Farhan Ahmad, Jian Xu
Regulation and function of transposable elements in cancer genomes. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Yoon Jung Kim, Michael Lee, Yi-Tsang Lee, Ji Jing, Jacob T Sanders, Giovanni A Botten, Lian He, Junhua Lyu, Yuannyu Zhang, Marcel Mettlen, Peter Ly, Yubin Zhou, Jian Xu
Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions. Science advances 9 (13) (2023)
Jingzhu Zhang, Liming Du, Bethany Davis, Zhimin Gu, Junhua Lyu, Zhiyu Zhao, Jian Xu, Sean J Morrison
Osteolectin increases bone elongation and body length by promoting growth plate chondrocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America 120 (22) (2023)
Giovanni A Botten, Yuannyu Zhang, Kseniia Dudnyk, Yoon Jung Kim, Xin Liu, Jacob T Sanders, Aygun Imanci, Nathalie M Droin, Hui Cao, Pranita Kaphle, Kathryn E Dickerson, Kirthi R Kumar, Mingyi Chen, Weina Chen, Eric Solary, Peter Ly, Jian Zhou, Jian Xu
Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription. Blood (2023)
Yoon Jung Kim, Michael Lee, Yi-Tsang Lee, Ji Jing, Jacob T Sanders, Giovanni A Botten, Lian He, Junhua Lyu, Yuannyu Zhang, Marcel Mettlen, Peter Ly, Yubin Zhou, Jian Xu
Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions. Science advances 9 (13) (2023)
Hsi-Hsien Hsieh, Huiyu Yao, Yue Ma, Yuannyu Zhang, Xue Xiao, Helen Stephens, Naureen Wajahat, Stephen S Chung, Lin Xu, Jian Xu, Raajit K Rampal, Lily Jun-Shen Huang
Epo-IGF1R cross talk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm. Blood 140 (22) (2022)
Junhua Lyu, Yuxuan Liu, Lihu Gong, Mingyi Chen, Yazan F Madanat, Yuannyu Zhang, Feng Cai, Zhimin Gu, Hui Cao, Pranita Kaphle, Yoon Jung Kim, Fatma N Kalkan, Helen Stephens, Kathryn E Dickerson, Min Ni, Weina Chen, Prapti A Patel, Alice S Mims, Uma Borate, Amy Burd, Sheng F Cai, Cheng Cameron Yin, Mingjian James You, Stephen S Chung, Robert H Collins, Ralph J DeBerardinis, Xin Liu, Jian Xu
Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance. Cancer discovery (2022)
McKenzie Patrick, Zhimin Gu, Gen Zhang, R Max Wynn, Pranita Kaphle, Hui Cao, Hieu Vu, Feng Cai, Xiaofei Gao, Yuannyu Zhang, Mingyi Chen, Min Ni, David T Chuang, Ralph J DeBerardinis, Jian Xu
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis. Nature metabolism (2022)
Yuxuan Liu, Zhimin Gu, Hui Cao, Pranita Kaphle, Junhua Lyu, Yuannyu Zhang, Wenhuo Hu, Stephen S Chung, Kathryn E Dickerson, Jian Xu
Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation. Nature communications 12 (1) (2021)
Yong Shen, Jeffrey M Verboon, Yuannyu Zhang, Nan Liu, Yoon Jung Kim, Samantha Marglous, Satish K Nandakumar, Richard A Voit, Claudia Fiorini, Ayesha Ejaz, Anindita Basak, Stuart H Orkin, Jian Xu, Vijay G Sankaran
A unified model of human hemoglobin switching through single-cell genome editing. Nature communications 12 (1) (2021)
Hye Ji Cha, Özgün Uyan, Yan Kai, Tianxin Liu, Qian Zhu, Zuzana Tothova, Giovanni A Botten, Jian Xu, Guo-Cheng Yuan, Job Dekker, Stuart H Orkin
Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture. Nature communications 12 (1) (2021)
Zhimin Gu, Kathryn E Dickerson, Jian Xu
Therapy Response and Outcome Explained by Leukemia Cell of Origin. Cancer discovery 10 (10) (2021)
Wei Fan, Shuang Tang, Xiaojuan Fan, Yi Fang, Xiaojiang Xu, Leping Li, Jian Xu, Jian-Liang Li, Zefeng Wang, Xiaoling Li
SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B. eLife 10 (2021)
Zhimin Gu, Yuxuan Liu, Yuannyu Zhang, Hui Cao, Junhua Lyu, Xun Wang, Annika Wylie, Simon J Newkirk, Amanda E Jones, Michael Lee, Giovanni A Botten, Mi Deng, Kathryn E Dickerson, Cheng Cheng Zhang, Wenfeng An, John M Abrams, Jian Xu
Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia. Nature genetics 53 (5) (2021)
Shiqi Tu, Mushan Li, Haojie Chen, Fengxiang Tan, Jian Xu, David J Waxman, Yijing Zhang, Zhen Shao
MAnorm2 for quantitatively comparing groups of ChIP-seq samples. Genome research 31 (1) (2020)
Kailong Li, Yuannyu Zhang, Xin Liu, Zhimin Gu, Hui Cao, Kathryn E Dickerson, Mingyi Chen, Weina Chen, Zhen Shao, Min Ni, Jian Xu
Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies. Cancer discovery 10 (5) (2020)
Kailong Li, Yuxuan Liu, Hui Cao, Yuannyu Zhang, Zhimin Gu, Xin Liu, Andy Yu, Pranita Kaphle, Kathryn E Dickerson, Min Ni, Jian Xu
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing. Nature communications 11 (1) (2020)
Wenqing Cai, Jialiang Huang, Qian Zhu, Bin E Li, Davide Seruggia, Pingzhu Zhou, Minh Nguyen, Yuko Fujiwara, Huafeng Xie, Zhenggang Yang, Danni Hong, Pengfei Ren, Jian Xu, William T Pu, Guo-Cheng Yuan, Stuart H Orkin
Enhancer dependence of cell-type-specific gene expression increases with developmental age. Proceedings of the National Academy of Sciences of the United States of America 117 (35) (2020)
Zhimin Gu, Yuxuan Liu, Feng Cai, McKenzie Patrick, Jakub Zmajkovic, Hui Cao, Yuannyu Zhang, Alpaslan Tasdogan, Mingyi Chen, Le Qi, Xin Liu, Kailong Li, Junhua Lyu, Kathryn E Dickerson, Weina Chen, Min Ni, Matthew E Merritt, Sean J Morrison, Radek C Skoda, Ralph J DeBerardinis, Jian Xu
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation. Cancer discovery 9 (9) (2019)
Mushan Li, Shiqi Tu, Zijia Li, Fengxiang Tan, Jian Liu, Qian Wang, Yuannyu Zhang, Jian Xu, Yijing Zhang, Feng Zhou, Zhen Shao
MAP: model-based analysis of proteomic data to detect proteins with significant abundance changes. Cell discovery 5 (2019)
Hongduo Sun, Jiawei Wang, Zhaohui Gong, Jiaying Yao, Yuangao Wang, Jian Xu, Guo-Cheng Yuan, Yijing Zhang, Zhen Shao
Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters. Cell discovery 4 (2018)