Ralph J DeBerardinis

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 69

Top Topics

Duchenne Muscular Dystrophy

Small Cell Lung Cancer

Renal Cell Carcinoma

Top Venues

Science advances

Nature metabolism

Science (New York, N.Y.)

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Niranjan Venkateswaran, Roy Garcia, M Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A S Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A Kilgore, Shun Fang, Isabella N Brown, Li Li, Emily Parks, Igor Lopes Dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V Grishin, Lisa Kinch, Lin Xu, Noelle S Williams, Jerry W Shay, Ralph J DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis. Nature communications 15 (1) (2024)
Divya Bezwada, Luigi Perelli, Nicholas P Lesner, Ling Cai, Bailey Brooks, Zheng Wu, Hieu S Vu, Varun Sondhi, Daniel L Cassidy, Stacy Yuan Kasitinon, Sherwin Kelekar, Feng Cai, Arin B Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Phyllis McDaniel, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M Poole, Yair Lotan, Solomon Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A Cadeddu, Prashant Mishra, Javier Garcia-Bermudez, Ivan Pedrosa, Payal Kapur, Kevin Dale Courtney, Craig R Malloy, Giannicola Genovese, Vitaly Margulis, Ralph J DeBerardinis
Mitochondrial complex I promotes kidney cancer metastasis. Nature (2024)
Xun Wang, Cameron J Menezes, Yuemeng Jia, Yi Xiao, Siva Sai Krishna Venigalla, Feng Cai, Meng-Hsiung Hsieh, Wen Gu Lai, Liming Du, Jessica Sudderth, Dohun Kim, Spencer D Shelton, Claire B Llamas, Yu-Hsuan Lin, Min Zhu, Salma Merchant, Divya Bezwada, Sherwin Kelekar, Lauren G Zacharias, Thomas P Mathews, Gerta Hoxhaj, R Max Wynn, Uttam K Tambar, Ralph J DeBerardinis, Hao Zhu, Prashant Mishra
Metabolic inflexibility promotes mitochondrial health during liver regeneration. Science (New York, N.Y.) 384 (6701) (2024)
Xun Wang, Cameron J Menezes, Yuemeng Jia, Yi Xiao, Siva Sai Krishna Venigalla, Feng Cai, Meng-Hsiung Hsieh, Wen Gu Lai, Liming Du, Jessica Sudderth, Dohun Kim, Spencer D Shelton, Claire B Llamas, Yu-Hsuan Lin, Min Zhu, Salma Merchant, Divya Bezwada, Sherwin Kelekar, Lauren G Zacharias, Thomas P Mathews, Gerta Hoxhaj, R Max Wynn, Uttam K Tambar, Ralph J DeBerardinis, Hao Zhu, Prashant Mishra
Metabolic inflexibility promotes mitochondrial health during liver regeneration. Science (New York, N.Y.) 384 (6701) (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism 6 (1) (2024)
Divya Bezwada, Luigi Perelli, Nicholas P Lesner, Ling Cai, Bailey Brooks, Zheng Wu, Hieu S Vu, Varun Sondhi, Daniel L Cassidy, Stacy Yuan Kasitinon, Sherwin Kelekar, Feng Cai, Arin B Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Phyllis McDaniel, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M Poole, Yair Lotan, Solomon Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A Cadeddu, Prashant Mishra, Javier Garcia-Bermudez, Ivan Pedrosa, Payal Kapur, Kevin Dale Courtney, Craig R Malloy, Giannicola Genovese, Vitaly Margulis, Ralph J DeBerardinis
Mitochondrial complex I promotes kidney cancer metastasis. Nature (2024)
Qiang Feng, Zachary T Bennett, Anthony Grichuk, Raymundo Pantoja, Tongyi Huang, Brandon Faubert, Gang Huang, Mingyi Chen, Ralph J DeBerardinis, Baran D Sumer, Jinming Gao
Severely polarized extracellular acidity around tumour cells. Nature biomedical engineering (2024)
Qiang Feng, Zachary T Bennett, Anthony Grichuk, Raymundo Pantoja, Tongyi Huang, Brandon Faubert, Gang Huang, Mingyi Chen, Ralph J DeBerardinis, Baran D Sumer, Jinming Gao
Severely polarized extracellular acidity around tumour cells. Nature biomedical engineering (2024)
Qiang Feng, Zachary T Bennett, Anthony Grichuk, Raymundo Pantoja, Tongyi Huang, Brandon Faubert, Gang Huang, Mingyi Chen, Ralph J DeBerardinis, Baran D Sumer, Jinming Gao
Severely polarized extracellular acidity around tumour cells. Nature biomedical engineering 8 (6) (2024)
Niranjan Venkateswaran, Roy Garcia, M Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A S Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A Kilgore, Shun Fang, Isabella N Brown, Li Li, Emily Parks, Igor Lopes Dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V Grishin, Lisa Kinch, Lin Xu, Noelle S Williams, Jerry W Shay, Ralph J DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis. Nature communications 15 (1) (2024)
Niranjan Venkateswaran, Roy Garcia, M Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A S Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A Kilgore, Shun Fang, Isabella N Brown, Li Li, Emily Parks, Igor Lopes Dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V Grishin, Lisa Kinch, Lin Xu, Noelle S Williams, Jerry W Shay, Ralph J DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis. Nature communications 15 (1) (2024)
Xun Wang, Cameron J Menezes, Yuemeng Jia, Yi Xiao, Siva Sai Krishna Venigalla, Feng Cai, Meng-Hsiung Hsieh, Wen Gu Lai, Liming Du, Jessica Sudderth, Dohun Kim, Spencer D Shelton, Claire B Llamas, Yu-Hsuan Lin, Min Zhu, Salma Merchant, Divya Bezwada, Sherwin Kelekar, Lauren G Zacharias, Thomas P Mathews, Gerta Hoxhaj, R Max Wynn, Uttam K Tambar, Ralph J DeBerardinis, Hao Zhu, Prashant Mishra
Metabolic inflexibility promotes mitochondrial health during liver regeneration. Science (New York, N.Y.) 384 (6701) (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism 6 (1) (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism (2024)
Eliot B Blatt, Ralph J DeBerardinis
Glutamine antagonists may KEAP lung cancer in check. Science advances 10 (13) (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism 6 (1) (2024)
Niranjan Venkateswaran, Roy Garcia, M Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A S Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A Kilgore, Shun Fang, Isabella N Brown, Li Li, Emily Parks, Igor Lopes Dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V Grishin, Lisa Kinch, Lin Xu, Noelle S Williams, Jerry W Shay, Ralph J DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis. Nature communications 15 (1) (2024)
Divya Bezwada, Luigi Perelli, Nicholas P Lesner, Ling Cai, Bailey Brooks, Zheng Wu, Hieu S Vu, Varun Sondhi, Daniel L Cassidy, Stacy Yuan Kasitinon, Sherwin Kelekar, Feng Cai, Arin B Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Phyllis McDaniel, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M Poole, Yair Lotan, Solomon Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A Cadeddu, Prashant Mishra, Javier Garcia-Bermudez, Ivan Pedrosa, Payal Kapur, Kevin Dale Courtney, Craig R Malloy, Giannicola Genovese, Vitaly Margulis, Ralph J DeBerardinis
Mitochondrial complex I promotes kidney cancer metastasis. Nature (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism 6 (1) (2024)
Niranjan Venkateswaran, Roy Garcia, M Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A S Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A Kilgore, Shun Fang, Isabella N Brown, Li Li, Emily Parks, Igor Lopes Dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V Grishin, Lisa Kinch, Lin Xu, Noelle S Williams, Jerry W Shay, Ralph J DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis. Nature communications 15 (1) (2024)
Eliot B Blatt, Ralph J DeBerardinis
Glutamine antagonists may KEAP lung cancer in check. Science advances 10 (13) (2024)
Xun Wang, Cameron J Menezes, Yuemeng Jia, Yi Xiao, Siva Sai Krishna Venigalla, Feng Cai, Meng-Hsiung Hsieh, Wen Gu Lai, Liming Du, Jessica Sudderth, Dohun Kim, Spencer D Shelton, Claire B Llamas, Yu-Hsuan Lin, Min Zhu, Salma Merchant, Divya Bezwada, Sherwin Kelekar, Lauren G Zacharias, Thomas P Mathews, Gerta Hoxhaj, R Max Wynn, Uttam K Tambar, Ralph J DeBerardinis, Hao Zhu, Prashant Mishra
Metabolic inflexibility promotes mitochondrial health during liver regeneration. Science (New York, N.Y.) 384 (6701) (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism (2024)
Xun Wang, Cameron J Menezes, Yuemeng Jia, Yi Xiao, Siva Sai Krishna Venigalla, Feng Cai, Meng-Hsiung Hsieh, Wen Gu Lai, Liming Du, Jessica Sudderth, Dohun Kim, Spencer D Shelton, Claire B Llamas, Yu-Hsuan Lin, Min Zhu, Salma Merchant, Divya Bezwada, Sherwin Kelekar, Lauren G Zacharias, Thomas P Mathews, Gerta Hoxhaj, R Max Wynn, Uttam K Tambar, Ralph J DeBerardinis, Hao Zhu, Prashant Mishra
Metabolic inflexibility promotes mitochondrial health during liver regeneration. Science (New York, N.Y.) 384 (6701) (2024)
Ling Cai, Ralph J DeBerardinis, Xiaowei Zhan, Guanghua Xiao, Yang Xie
Navigating electronic health record accuracy by examination of sex incongruent conditions. Journal of the American Medical Informatics Association : JAMIA (2024)
Hai Wei, Yi M Weaver, Chendong Yang, Yuan Zhang, Guoli Hu, Courtney M Karner, Matthew H Sieber, Ralph J DeBerardinis, Benjamin P Weaver
Proteolytic activation of fatty acid synthase signals pan-stress resolution. Nature metabolism 6 (1) (2024)
Zhenkang Chen, Bogdan Bordieanu, Rushendhiran Kesavan, Nicholas P Lesner, Siva Sai Krishna Venigalla, Spencer D Shelton, Ralph J DeBerardinis, Prashant Mishra
Lactate metabolism is essential in early-onset mitochondrial myopathy. Science advances 9 (1) (2023)
Zhenkang Chen, Bogdan Bordieanu, Rushendhiran Kesavan, Nicholas P Lesner, Siva Sai Krishna Venigalla, Spencer D Shelton, Ralph J DeBerardinis, Prashant Mishra
Lactate metabolism is essential in early-onset mitochondrial myopathy. Science advances 9 (1) (2023)
Mª Carmen Ocaña, Manuel Bernal, Chendong Yang, Carlos Caro, Alejandro Domínguez, Hieu S Vu, Casimiro Cárdenas, María Luisa García-Martín, Ralph J DeBerardinis, Ana R Quesada, Beatriz Martínez-Poveda, Miguel Ángel Medina
New insights in the targets of action of dimethyl fumarate in endothelial cells: effects on energetic metabolism and serine synthesis in vitro and in vivo. Communications biology 6 (1) (2023)
Divya Bezwada, Nicholas P Lesner, Bailey Brooks, Hieu Sy Vu, Zheng Wu, Ling Cai, Stacy Yuan Kasitinon, Sherwin Kelekar, Feng Cai, Arin B Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M Poole, Yair Lotan, Solomon L Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A Cadeddu, Prashant Mishra, Ivan Pedrosa, Payal Kapur, Kevin Dale Courtney, Craig R Malloy, Vitaly Margulis, Ralph J DeBerardinis
Mitochondrial metabolism in primary and metastatic human kidney cancers. bioRxiv : the preprint server for biology (2023)
Sibtain Ahmed, Ayra Siddiqui, Ralph J DeBerardinis, Min Ni, Wen Gu Lai, Feng Cai, Hieu S Vu, Bushra Afroze
L-2-hydroxyglutaric aciduria - review of literature and case series. Annals of medicine and surgery (2012) 85 (4) (2023)
Zhenkang Chen, Bogdan Bordieanu, Rushendhiran Kesavan, Nicholas P Lesner, Siva Sai Krishna Venigalla, Spencer D Shelton, Ralph J DeBerardinis, Prashant Mishra
Lactate metabolism is essential in early-onset mitochondrial myopathy. Science advances 9 (1) (2023)
Zhenkang Chen, Bogdan Bordieanu, Rushendhiran Kesavan, Nicholas P Lesner, Siva Sai Krishna Venigalla, Spencer D Shelton, Ralph J DeBerardinis, Prashant Mishra
Lactate metabolism is essential in early-onset mitochondrial myopathy. Science advances 9 (1) (2023)
Zhenkang Chen, Bogdan Bordieanu, Rushendhiran Kesavan, Nicholas P Lesner, Siva Sai Krishna Venigalla, Spencer D Shelton, Ralph J DeBerardinis, Prashant Mishra
Lactate metabolism is essential in early-onset mitochondrial myopathy. Science advances 9 (1) (2023)
Sibtain Ahmed, Ayra Siddiqui, Ralph J DeBerardinis, Min Ni, Wen Gu Lai, Feng Cai, Hieu S Vu, Bushra Afroze
L-2-hydroxyglutaric aciduria - review of literature and case series. Annals of medicine and surgery (2012) 85 (4) (2023)
Sibtain Ahmed, Ayra Siddiqui, Ralph J DeBerardinis, Min Ni, Wen Gu Lai, Feng Cai, Hieu S Vu, Bushra Afroze
L-2-hydroxyglutaric aciduria - review of literature and case series. Annals of medicine and surgery (2012) 85 (4) (2023)
Divya Bezwada, Nicholas P Lesner, Bailey Brooks, Hieu Sy Vu, Zheng Wu, Ling Cai, Stacy Yuan Kasitinon, Sherwin Kelekar, Feng Cai, Arin B Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M Poole, Yair Lotan, Solomon L Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A Cadeddu, Prashant Mishra, Ivan Pedrosa, Payal Kapur, Kevin Dale Courtney, Craig R Malloy, Vitaly Margulis, Ralph J DeBerardinis
Mitochondrial metabolism in primary and metastatic human kidney cancers. bioRxiv : the preprint server for biology (2023)
Abir Mukherjee, Divya Bezwada, Francesco Greco, Malu Zandbergen, Tong Shen, Chun Yi Chiang, Medine Tasdemir, Johannes Fahrmann, Dmitry Grapov, Michael R La Frano, Hieu S Vu, Brandon Faubert, John W Newman, Liam A McDonnell, Luigi Nezi, Oliver Fiehn, Ralph J DeBerardinis, Ernst Lengyel
Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis. Nature metabolism (2023)
Ling Cai, Ralph J DeBerardinis, Yang Xie, John D Minna, Guanghua Xiao
A comparative study of neuroendocrine heterogeneity in small cell lung cancer and neuroblastoma. Molecular cancer research : MCR (2023)
Pravat Kumar Parida, Mauricio Marquez-Palencia, Suvranil Ghosh, Nitin Khandelwal, Kangsan Kim, Vidhya Nair, Xiao-Zheng Liu, Hieu S Vu, Lauren G Zacharias, Paula I Gonzalez Ericsson, Melinda E Sanders, Bret C Mobley, Jeffrey G McDonald, Andrew Lemoff, Yan Peng, Cheryl Lewis, Gonçalo Vale, Nils Halberg, Carlos L Arteaga, Ariella B Hanker, Ralph J DeBerardinis, Srinivas Malladi
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases. Nature cancer (2023)
Eliot B Blatt, Karla Parra, Antje Neeb, Lorenzo Buroni, Denisa Bogdan, Wei Yuan, Yunpeng Gao, Collin Gilbreath, Alec Paschalis, Suzanne Carreira, Ralph J DeBerardinis, Ram S Mani, Johann S de Bono, Ganesh V Raj
Critical role of antioxidant programs in enzalutamide-resistant prostate cancer. Oncogene (2023)
Ling Cai, Ralph J DeBerardinis, Yang Xie, John D Minna, Guanghua Xiao
A Comparative Study of Neuroendocrine Heterogeneity in Small Cell Lung Cancer and Neuroblastoma. Molecular cancer research : MCR (2023)
Caroline R Bartman, Brandon Faubert, Joshua D Rabinowitz, Ralph J DeBerardinis
Metabolic pathway analysis using stable isotopes in patients with cancer. Nature reviews. Cancer (2023)
Panayotis Pachnis, Zheng Wu, Brandon Faubert, Alpaslan Tasdogan, Wen Gu Lai, Spencer D Shelton, Ashley Solmonson, Aparna D Rao, Akash K Kaushik, Thomas J Rogers, Jessalyn M Ubellacker, Collette A LaVigne, Chendong Yang, Bookyung Ko, Vijayashree Ramesh, Jessica Sudderth, Lauren G Zacharias, Misty S Martin-Sandoval, Duyen Do, Thomas P Mathews, Zhiyu Zhao, Prashant Mishra, Sean J Morrison, Ralph J DeBerardinis
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors. Science advances 8 (35) (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Marisa K Kilgour, Sarah MacPherson, Lauren G Zacharias, Jodi LeBlanc, Sindy Babinszky, Gabrielle Kowalchuk, Scott Parks, Ryan D Sheldon, Russell G Jones, Ralph J DeBerardinis, Phineas T Hamilton, Peter Hamilton Watson, Julian J Lum
Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer. Nature protocols 17 (11) (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Andrew W Hahn, Ashley V Menk, Dayana B Rivadeneira, Ryan C Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K Mishra, Tuba Nur Gide, Camelia Quek, Yan Zang, Christine N Spencer, Alexander M Menzies, Carrie R Daniel-MacDougall, Courtney W Hudgens, Theodore Scott Nowicki, Lauren E Haydu, Md Abdul Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M Burton, Jared C Malke, Julie M Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E Woodman, Vashisht Gopal Y N, Renato A Guerrieri, Grant M Fischer, Jian Wang, Khalida M Wani, John F Thompson, Jeffrey E Lee, Patrick Hwu, Nadim J Ajami, Jeffrey E Gershenwald, Georgina V Long, Richard A Scolyer, Michael T Tetzlaff, Alexander J F Lazar, Dirk Schadendorf, Jennifer A Wargo, Joanne M Jeter, Ralph J DeBerardinis, Han Liang, P Andrew Futreal, Jianhua Zhang, James S Wilmott, Weiyi Peng, Michael A Davies, Greg M Delgoffe, Yana G Najjar, Jennifer Leigh McQuade
Obesity is associated with altered tumor metabolism in metastatic melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Junhua Lyu, Yuxuan Liu, Lihu Gong, Mingyi Chen, Yazan F Madanat, Yuannyu Zhang, Feng Cai, Zhimin Gu, Hui Cao, Pranita Kaphle, Yoon Jung Kim, Fatma N Kalkan, Helen Stephens, Kathryn E Dickerson, Min Ni, Weina Chen, Prapti A Patel, Alice S Mims, Uma Borate, Amy Burd, Sheng F Cai, Cheng Cameron Yin, Mingjian James You, Stephen S Chung, Robert H Collins, Ralph J DeBerardinis, Xin Liu, Jian Xu
Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance. Cancer discovery (2022)
Ashley Solmonson, Brandon Faubert, Wen Gu Lai, Aparna Rao, Mitzy A Cowdin, Ivan Menendez-Montes, Sherwin Kelekar, Thomas J Rogers, Chunxiao Pan, Gerardo Guevara, Amy Tarangelo, Lauren G Zacharias, Misty S Martin-Sandoval, Duyen Do, Panayotis Pachnis, Dennis Dumesnil, Thomas P Mathews, Alpaslan Tasdogan, An Pham, Ling Cai, Zhiyu Zhao, Min Ni, Ondine Cleaver, Hesham A Sadek, Sean J Morrison, Ralph J DeBerardinis
Compartmentalized metabolism supports midgestation mammalian development. Nature 604 (7905) (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Akash K Kaushik, Amy Tarangelo, Lindsey K Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina Toffessi Tcheuyap, Faeze Saatchi, Quyen N Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D Rao, Brandon Faubert, Panayotis Pachnis, Lauren G Zacharias, Hieu Vu, Feng Cai, Thomas P Mathews, Giannicola Genovese, Barbara S Slusher, Payal Kapur, Xiankai Sun, Matthew E Merritt, James Brugarolas, Ralph J DeBerardinis
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science advances 8 (50) (2022)
Peng Wei, Alex J Bott, Ahmad A Cluntun, Jeffrey T Morgan, Corey N Cunningham, John C Schell, Yeyun Ouyang, Scott B Ficarro, Jarrod A Marto, Nika N Danial, Ralph J DeBerardinis, Jared Rutter
Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway. Science advances 8 (39) (2022)
McKenzie Patrick, Zhimin Gu, Gen Zhang, R Max Wynn, Pranita Kaphle, Hui Cao, Hieu Vu, Feng Cai, Xiaofei Gao, Yuannyu Zhang, Mingyi Chen, Min Ni, David T Chuang, Ralph J DeBerardinis, Jian Xu
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis. Nature metabolism (2022)
Brandon Faubert, Alpaslan Tasdogan, Sean J Morrison, Thomas P Mathews, Ralph J DeBerardinis
Stable isotope tracing to assess tumor metabolism in vivo. Nature protocols 16 (11) (2021)
Marisa K Kilgour, Sarah MacPherson, Lauren G Zacharias, Abigail E Ellis, Ryan D Sheldon, Elaine Y Liu, Sarah Keyes, Brenna Pauly, Gillian A Carleton, Bertrand Allard, Julian Smazynski, Kelsey S Williams, Peter Hamilton Watson, John Stagg, Brad H Nelson, Ralph J DeBerardinis, Russell G Jones, Phineas T Hamilton, Julian J Lum
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer. Science advances 7 (4) (2021)
Crystal S Conn, Haojun Yang, Harrison J Tom, Kenji Ikeda, Juan A Oses-Prieto, Hieu Vu, Yasuo Oguri, Supna Nair, Ryan M Gill, Shingo Kajimura, Ralph J DeBerardinis, Alma L Burlingame, Davide Ruggero
The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. Nature metabolism 3 (2) (2021)
Ralph J DeBerardinis, Navdeep S Chandel
We need to talk about the Warburg effect. Nature metabolism 2 (2) (2021)
Tran Hong Diem, Rushendhiran Kesavan, Halie Rion, Mona Hoseini Soflaee, Ashley Solmonson, Divya Bezwada, Hieu S Vu, Feng Cai, John A Phillips, Ralph J DeBerardinis, Gerta Hoxhaj
Mitochondrial NADP+ is essential for proline biosynthesis during cell growth. Nature metabolism 3 (4) (2021)
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