John K Pratt

ORCID

Publication Activity (10 Years)

Years Active: 2017-2020
Publications (10 Years): 5

Top Venues

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

George S Sheppard, Le Wang, Steven D Fidanze, Lisa A Hasvold, Dachun Liu, John K Pratt, Chang H Park, Kenton Longenecker, Wei Qiu, Maricel Torrent, Peter J Kovar, Mai Bui, Emily Faivre, Xiaoli Huang, Xiaoyu Lin, Denise Wilcox, Lu Zhang, Yu Shen, Daniel H Albert, Terrance J Magoc, Ganesh Rajaraman, Warren M Kati, Keith F McDaniel
Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain. Journal of medicinal chemistry 63 (10) (2020)
John T Randolph, A Chris Krueger, Pamela L Donner, John K Pratt, Dachun Liu, Christopher E Motter, Todd W Rockway, Michael D Tufano, Rolf Wagner, Hock B Lim, Jill M Beyer, Rubina Mondal, Neeta S Panchal, Lynn Colletti, Yaya Liu, Gennadiy Koev, Warren M Kati, Lisa E Hernandez, David W A Beno, Kenton L Longenecker, Kent D Stewart, Emily O Dumas, Akhteruzzaman Molla, Clarence J Maring
Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability. Journal of medicinal chemistry 61 (3) (2018)
Rolf Wagner, John T Randolph, Sachin V Patel, Lissa Nelson, Mark A Matulenko, Ryan Keddy, John K Pratt, Dachun Liu, A Chris Krueger, Pamela L Donner, Douglas K Hutchinson, Charles Flentge, David Betebenner, Todd Rockway, Clarence J Maring, Teresa I Ng, Preethi Krishnan, Tami Pilot-Matias, Christine Collins, Neeta Panchal, Thomas Reisch, Tatyana Dekhtyar, Rubina Mondal, DeAnne F Stolarik, Yi Gao, Wenqing Gao, David A Beno, Warren M Kati
Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530). Journal of medicinal chemistry 61 (9) (2018)
Le Wang, John K Pratt, Todd Soltwedel, George S Sheppard, Steven D Fidanze, Dachun Liu, Lisa A Hasvold, Robert A Mantei, James H Holms, William J McClellan, Michael D Wendt, Carol Wada, Robin Frey, T Matthew Hansen, Robert Hubbard, Chang H Park, Leiming Li, Terrance J Magoc, Daniel H Albert, Xiaoyu Lin, Scott E Warder, Peter Kovar, Xiaoli Huang, Denise Wilcox, Rongqi Wang, Ganesh Rajaraman, Andrew M Petros, Charles W Hutchins, Sanjay C Panchal, Chaohong Sun, Steven W Elmore, Yu Shen, Warren M Kati, Keith F McDaniel
Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors. Journal of medicinal chemistry 60 (9) (2017)
Keith F McDaniel, Le Wang, Todd Soltwedel, Steven D Fidanze, Lisa A Hasvold, Dachun Liu, Robert A Mantei, John K Pratt, George S Sheppard, Mai H Bui, Emily J Faivre, Xiaoli Huang, Leiming Li, Xiaoyu Lin, Rongqi Wang, Scott E Warder, Denise Wilcox, Daniel H Albert, Terrance J Magoc, Ganesh Rajaraman, Chang H Park, Charles W Hutchins, Jianwei J Shen, Rohinton P Edalji, Chaohong C Sun, Ruth Martin, Wenqing Gao, Shekman Wong, Guowei Fang, Steven W Elmore, Yu Shen, Warren M Kati
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor. Journal of medicinal chemistry 60 (20) (2017)

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Publication Activity (10 Years)

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John K Pratt