Keith F McDaniel

Publication Activity (10 Years)

Years Active: 2017-2021
Publications (10 Years): 4

Top Topics

Convolutional Neural Network

Hiv Infected Patients

Acinetobacter Baumannii

Top Venues

Journal of medicinal chemistry

Journal of chemical information and modeling

This page only lists publications with an associated author ORCID identifier.

Publications

Richard S Hong, Alessandra Mattei, Ahmad Y Sheikh, Rajni Miglani Bhardwaj, Michael A Bellucci, Keith F McDaniel, M Olivia Pierce, Guangxu Sun, Sizhu Li, Lingle Wang, Sayan Mondal, Jianguo Ji, Thomas B Borchardt
Novel Physics-Based Ensemble Modeling Approach That Utilizes 3D Molecular Conformation and Packing to Access Aqueous Thermodynamic Solubility: A Case Study of Orally Available Bromodomain and Extraterminal Domain Inhibitor Lead Optimization Series. Journal of chemical information and modeling 61 (3) (2021)
George S Sheppard, Le Wang, Steven D Fidanze, Lisa A Hasvold, Dachun Liu, John K Pratt, Chang H Park, Kenton Longenecker, Wei Qiu, Maricel Torrent, Peter J Kovar, Mai Bui, Emily Faivre, Xiaoli Huang, Xiaoyu Lin, Denise Wilcox, Lu Zhang, Yu Shen, Daniel H Albert, Terrance J Magoc, Ganesh Rajaraman, Warren M Kati, Keith F McDaniel
Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain. Journal of medicinal chemistry 63 (10) (2020)
Koushi Hidaka, Tooru Kimura, Rajesh Sankaranarayanan, Jun Wang, Keith F McDaniel, Dale J Kempf, Masanori Kameoka, Motoyasu Adachi, Ryota Kuroki, Jeffrey-Tri Nguyen, Yoshio Hayashi, Yoshiaki Kiso
Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine. Journal of medicinal chemistry 61 (12) (2018)
Keith F McDaniel, Le Wang, Todd Soltwedel, Steven D Fidanze, Lisa A Hasvold, Dachun Liu, Robert A Mantei, John K Pratt, George S Sheppard, Mai H Bui, Emily J Faivre, Xiaoli Huang, Leiming Li, Xiaoyu Lin, Rongqi Wang, Scott E Warder, Denise Wilcox, Daniel H Albert, Terrance J Magoc, Ganesh Rajaraman, Chang H Park, Charles W Hutchins, Jianwei J Shen, Rohinton P Edalji, Chaohong C Sun, Ruth Martin, Wenqing Gao, Shekman Wong, Guowei Fang, Steven W Elmore, Yu Shen, Warren M Kati
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor. Journal of medicinal chemistry 60 (20) (2017)