John Löfblom

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 25

Top Topics

Renal Cell Carcinoma

Monoclonal Antibody

Positron Emission Tomography

Top Venues

International journal of molecular sciences

Scientific reports

Molecular pharmaceutics

This page only lists publications with an associated author ORCID identifier.

Publications

Sebastian W Meister, Luke Parks, Leonie Kolmar, Anna Mestre Borras, Stefan Ståhl, John Löfblom
Engineering of TEV protease variants with redesigned substrate specificity. Biotechnology journal (2023)
Linnea Charlotta Hjelm, Hanna Lindberg, Stefan Ståhl, John Löfblom
Construction and Validation of a New Naïve Sequestrin Library for Directed Evolution of Binders against Aggregation-Prone Peptides. International journal of molecular sciences 24 (1) (2023)
Linnea Charlotta Hjelm, Hanna Lindberg, Stefan Ståhl, John Löfblom
Affibody Molecules Intended for Receptor-Mediated Transcytosis via the Transferrin Receptor. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Linnea Charlotta Hjelm, Hanna Lindberg, Stefan Ståhl, John Löfblom
Construction and Validation of a New Naïve Sequestrin Library for Directed Evolution of Binders against Aggregation-Prone Peptides. International journal of molecular sciences 24 (1) (2023)
Linnea Charlotta Hjelm, Hanna Lindberg, Stefan Ståhl, John Löfblom
Construction and Validation of a New Naïve Sequestrin Library for Directed Evolution of Binders against Aggregation-Prone Peptides. International journal of molecular sciences 24 (1) (2023)
Sara Sophie Rinne, Wen Yin, Anna Mestre Borras, Ayman Abouzayed, Charles Dahlsson Leitao, Anzhelika Vorobyeva, John Löfblom, Stefan Ståhl, Anna Orlova, Torbjörn Gräslund
Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules. Biomedicines 10 (6) (2022)
Sara Sophie Rinne, Charles Dahlsson Leitao, Ayman Abouzayed, Anzhelika Vorobyeva, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers. Cancers 13 (19) (2021)
Maryam Oroujeni, Tianqi Xu, Katherine Gagnon, Sara S Rinne, Jan Weis, Javad Garousi, Ken G Andersson, John Löfblom, Anna Orlova, Vladimir Tolmachev
The Use of a Non-Conventional Long-Lived Gallium Radioisotope 66Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR:2377 Affibody Molecule. Pharmaceutics 13 (2) (2021)
Sebastian W Meister, Linnea Charlotta Hjelm, Melanie Dannemeyer, Hanna Tegel, Hanna Lindberg, Stefan Ståhl, John Löfblom
An Affibody Molecule Is Actively Transported into the Cerebrospinal Fluid via Binding to the Transferrin Receptor. International journal of molecular sciences 21 (8) (2020)
Sara S Rinne, Tianqi Xu, Charles Dahlsson Leitao, Stefan Ståhl, John Löfblom, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva
Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules. International journal of molecular sciences 21 (4) (2020)
Sara S Rinne, Charles Dahlsson Leitao, Zahra Saleh-Nihad, Bogdan Mitran, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules. International journal of molecular sciences 21 (6) (2020)
Himanshu Chaudhary, Sebastian W Meister, Henrik Zetterberg, John Löfblom, Christofer Lendel
Dissecting the Structural Organization of Multiprotein Amyloid Aggregates Using a Bottom-Up Approach. ACS chemical neuroscience 11 (10) (2020)
Charles Dahlsson Leitao, Sara S Rinne, Mohamed Altai, Olga Vorontsova, Finn Dunås, Per Jonasson, Vladimir Tolmachev, John Löfblom, Stefan Ståhl, Anna Orlova
Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model. Pharmaceutics 12 (6) (2020)
Charles Dahlsson Leitao, Sara S Rinne, Bogdan Mitran, Anzhelika Vorobyeva, Ken G Andersson, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers. International journal of molecular sciences 20 (5) (2019)
Sara S Rinne, Charles Dahlsson Leitao, Bogdan Mitran, Tarek Z Bass, Ken G Andersson, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111. Scientific reports 9 (1) (2019)
Sara S Rinne, Charles Dahlsson Leitao, Joshua Gentry, Bogdan Mitran, Ayman Abouzayed, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
Increase in negative charge of 68Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules. Scientific reports 9 (1) (2019)
Rezan Güler, Naresh Thatikonda, Hawraa Ali Ghani, My Hedhammar, John Löfblom
VEGFR2-Specific Ligands Based on Affibody Molecules Demonstrate Agonistic Effects when Tetrameric in the Soluble Form or Immobilized via Spider Silk. ACS biomaterials science & engineering 5 (12) (2019)
Sebastian W Meister, Natalie M Hendrikse, John Löfblom
Directed evolution of the 3C protease from coxsackievirus using a novel fluorescence-assisted intracellular method. Biological chemistry 400 (3) (2019)
Javad Garousi, Fokko J Huizing, Anzhelika Vorobyeva, Bogdan Mitran, Ken G Andersson, Charles Dahlsson Leitao, Fredrik Y Frejd, John Löfblom, Johan Bussink, Anna Orlova, Sandra Heskamp, Vladimir Tolmachev
Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts. Scientific reports 9 (1) (2019)
Sergey Deyev, Anzhelika Vorobyeva, Alexey Schulga, Galina Proshkina, Rezan Güler, John Löfblom, Bogdan Mitran, Javad Garousi, Mohamed Altai, Jos Buijs, Vladimir Chernov, Anna Orlova, Vladimir Tolmachev
Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties. Molecular pharmaceutics 16 (3) (2019)
Maria Rosestedt, Ken G Andersson, Sara S Rinne, Charles Dahlsson Leitao, Bogdan Mitran, Anzhelika Vorobyeva, Stefan Ståhl, John Löfblom, Vladimir Tolmachev, Anna Orlova
Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake. Scientific reports 9 (1) (2019)
Anzhelika Vorobyeva, Alexey Schulga, Elena Konovalova, Rezan Güler, John Löfblom, Mattias Sandström, Javad Garousi, Vladimir Chernov, Olga Bragina, Anna Orlova, Vladimir Tolmachev, Sergey M Deyev
Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3. Scientific reports 9 (1) (2019)
Mohamed Altai, Charles Dahlsson Leitao, Sara S Rinne, Anzhelika Vorobyeva, Christina Atterby, Stefan Ståhl, Vladimir Tolmachev, John Löfblom, Anna Orlova
Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs. Cells 7 (10) (2018)
Anna Orlova, Tarek Z Bass, Sara S Rinne, Charles Dahlsson Leitao, Maria Rosestedt, Christina Atterby, Lindvi Gudmundsdotter, Fredrik Y Frejd, John Löfblom, Vladimir Tolmachev, Stefan Ståhl
Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab. Molecular pharmaceutics 15 (8) (2018)
John Löfblom, Ralf Rosenstein, Minh-Thu Nguyen, Stefan Ståhl, Friedrich Götz
Staphylococcus carnosus: from starter culture to protein engineering platform. Applied microbiology and biotechnology 101 (23-24) (2017)