Anzhelika Vorobyeva

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 43

Top Venues

International journal of molecular sciences

Pharmaceutics

Cancers

Scientific reports

École Polytechnique Fédérale de Lausanne (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

École Polytechnique Fédérale de Lausanne Sep 1o 2012 - Sep 30o 2016

Switzerland

PHD

Publications

Tianqi Xu, Alexey A Schulga, Elena Konovalova, Sara Sophie Rinne, Hongchao Zhang, Olga Vorontsova, Anna Orlova, Sergey Mikhailovich Deyev, Vladimir Tolmachev, Anzhelika Vorobyeva
Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model. International journal of molecular sciences 24 (3) (2023)
Yongsheng Liu, Tianqi Xu, Anzhelika Vorobyeva, Annika Loftenius, Vitalina Bodenko, Anna Orlova, Fredrik Y Frejd, Vladimir Tolmachev
Radionuclide Therapy of HER2-Expressing Xenografts Using [ 177 Lu]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab. Cancers 15 (9) (2023)
Tianqi Xu, Alexey A Schulga, Elena Konovalova, Sara Sophie Rinne, Hongchao Zhang, Olga Vorontsova, Anna Orlova, Sergey Mikhailovich Deyev, Vladimir Tolmachev, Anzhelika Vorobyeva
Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model. International journal of molecular sciences 24 (3) (2023)
Yongsheng Liu, Tianqi Xu, Anzhelika Vorobyeva, Annika Loftenius, Vitalina Bodenko, Anna Orlova, Fredrik Y Frejd, Vladimir Tolmachev
Radionuclide Therapy of HER2-Expressing Xenografts Using [ 177 Lu]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab. Cancers 15 (9) (2023)
Tianqi Xu, Alexey A Schulga, Elena Konovalova, Sara Sophie Rinne, Hongchao Zhang, Olga Vorontsova, Anna Orlova, Sergey Mikhailovich Deyev, Vladimir Tolmachev, Anzhelika Vorobyeva
Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model. International journal of molecular sciences 24 (3) (2023)
Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Mikhailovich Deyev, Elena Konovalova, Alexey A Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika Vorobyeva
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy. International journal of molecular sciences 23 (23) (2022)
Javad Garousi, Tianqi Xu, Yongsheng Liu, Olga Vorontsova, Sophia Hober, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund, Anzhelika Vorobyeva
Experimental HER2-Targeted Therapy Using ADAPT6-ABD-mcDM1 in Mice Bearing SKOV3 Ovarian Cancer Xenografts: Efficacy and Selection of Companion Imaging Counterpart. Pharmaceutics 14 (8) (2022)
Tianqi Xu, Jie Zhang, Maryam Oroujeni, Maria S Tretyakova, Vitalina Bodenko, Mikhail V Belousov, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva, Torbjörn Gräslund
Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2. Pharmaceutics 14 (3) (2022)
Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Mikhailovich Deyev, Elena Konovalova, Alexey A Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika Vorobyeva
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy. International journal of molecular sciences 23 (23) (2022)
Mariia Larkina, Evgenii Plotnikov, Ekaterina A Bezverkhniaia, Yulia Shabanova, Maria Tretyakova, Feruza Yuldasheva, Roman Zelchan, Alexey A Schulga, Elena Konovalova, Anzhelika Vorobyeva, Javad Garousi, Torbjörn Gräslund, Mikhail Belousov, Vladimir Tolmachev, Sergey Mikhailovich Deyev
Comparative Preclinical Evaluation of Peptide-Based Chelators for the Labeling of DARPin G3 with 99m Tc for Radionuclide Imaging of HER2 Expression in Cancer. International journal of molecular sciences 23 (21) (2022)
Vladimir Tolmachev, Anzhelika Vorobyeva
Radionuclides in Diagnostics and Therapy of Malignant Tumors: New Development. Cancers 14 (2) (2022)
Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Mikhailovich Deyev, Elena Konovalova, Alexey A Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika Vorobyeva
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy. International journal of molecular sciences 23 (23) (2022)
Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Mikhailovich Deyev, Elena Konovalova, Alexey A Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika Vorobyeva
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy. International journal of molecular sciences 23 (23) (2022)
Yongsheng Liu, Shengze Yu, Tianqi Xu, Vitalina Bodenko, Anna Orlova, Maryam Oroujeni, Sara Sophie Rinne, Vladimir Tolmachev, Anzhelika Vorobyeva, Torbjörn Gräslund
Preclinical Evaluation of a New Format of 68 Ga- and 111 In-Labeled Affibody Molecule Z IGF-1R:4551 for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT. Pharmaceutics 14 (7) (2022)
Sara Sophie Rinne, Wen Yin, Anna Mestre Borras, Ayman Abouzayed, Charles Dahlsson Leitao, Anzhelika Vorobyeva, John Löfblom, Stefan Ståhl, Anna Orlova, Torbjörn Gräslund
Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules. Biomedicines 10 (6) (2022)
Yongsheng Liu, Rezan Güler, Yunqi Liao, Anzhelika Vorobyeva, Olof Widmark, Theodorus J Meuleman, Anna Baierl, Leendert J van den Bos, Robert Naasz, Vitalina Bodenko, Anna Orlova, Caroline Ekblad, Vladimir Tolmachev, Fredrik Y Frejd
Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis. Pharmaceutics 14 (11) (2022)
Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Mikhailovich Deyev, Elena Konovalova, Alexey A Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika Vorobyeva
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy. International journal of molecular sciences 23 (23) (2022)
Yongsheng Liu, Anzhelika Vorobyeva, Anna Orlova, Mark W Konijnenberg, Tianqi Xu, Olga Bragina, Annika Loftenius, Erica Rosander, Fredrik Y Frejd, Vladimir Tolmachev
Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule 188 Re-ZHER2:41071. Pharmaceutics 14 (5) (2022)
Maryam Oroujeni, Sara Sophie Rinne, Anzhelika Vorobyeva, Annika Loftenius, Joachim Feldwisch, Per Jonasson, Vladimir Chernov, Anna Orlova, Fredrik Y Frejd, Vladimir Tolmachev
Preclinical Evaluation of 99mTc-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake. International journal of molecular sciences 22 (5) (2021)
Sergey Mikhailovich Deyev, Tianqi Xu, Yongsheng Liu, Alexey A Schulga, Elena Konovalova, Javad Garousi, Sara Sophie Rinne, Maria Larkina, Haozhong Ding, Torbjörn Gräslund, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva
Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1. Cancers 13 (14) (2021)
Hanna Tano, Maryam Oroujeni, Anzhelika Vorobyeva, Kristina Westerlund, Yongsheng Liu, Tianqi Xu, Daniel Vasconcelos, Anna Orlova, Amelie Eriksson Karlström, Vladimir Tolmachev
Comparative Evaluation of Novel 177Lu-Labeled PNA Probes for Affibody-Mediated PNA-Based Pretargeting. Cancers 13 (3) (2021)
Tianqi Xu, Anzhelika Vorobyeva, Alexey A Schulga, Elena Konovalova, Olga Vorontsova, Haozhong Ding, Torbjörn Gräslund, Liubov Alexandrovna Tashireva, Anna Orlova, Vladimir Tolmachev, Sergey Mikhailovich Deyev
Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model. Cancers 13 (16) (2021)
Yongsheng Liu, Anzhelika Vorobyeva, Tianqi Xu, Anna Orlova, Annika Loftenius, Theresa Bengtsson, Per Jonasson, Vladimir Tolmachev, Fredrik Y Frejd
Comparative Preclinical Evaluation of HER2-Targeting ABD-Fused Affibody® Molecules 177Lu-ABY-271 and 177Lu-ABY-027: Impact of DOTA Position on ABD Domain. Pharmaceutics 13 (6) (2021)
Sara Sophie Rinne, Charles Dahlsson Leitao, Ayman Abouzayed, Anzhelika Vorobyeva, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers. Cancers 13 (19) (2021)
Haozhong Ding, Tianqi Xu, Jie Zhang, Vladimir Tolmachev, Maryam Oroujeni, Anna Orlova, Torbjörn Gräslund, Anzhelika Vorobyeva
Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution. Pharmaceutics 13 (3) (2021)
Wen Yin, Tianqi Xu, Mohamed Altai, Maryam Oroujeni, Jie Zhang, Anzhelika Vorobyeva, Olga Vorontsova, Sergey V Vtorushin, Vladimir Tolmachev, Torbjörn Gräslund, Anna Orlova
The Influence of Domain Permutations of an Albumin-Binding Domain-Fused HER2-Targeting Affibody-Based Drug Conjugate on Tumor Cell Proliferation and Therapy Efficacy. Pharmaceutics 13 (11) (2021)
Javad Garousi, Haozhong Ding, Emma von Witting, Tianqi Xu, Anzhelika Vorobyeva, Maryam Oroujeni, Anna Orlova, Sophia Hober, Torbjörn Gräslund, Vladimir Tolmachev
Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein. Pharmaceutics 13 (11) (2021)
Olga Bragina, Vladimir Chernov, Alexey A Schulga, Elena V Konovalova, Eugeniy Garbukov, Anzhelika Vorobyeva, Anna Orlova, Liubov Alexandrovna Tashireva, Jens Sorensen, Roman Zelchan, Anna Medvedeva, Sergey Mikhailovich Deyev, Vladimir Tolmachev
Phase I trial of 99mTc-(HE)3-G3, a DARPin-based probe for imaging of HER2 expression in breast cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine (2021)
Sara S Rinne, Tianqi Xu, Charles Dahlsson Leitao, Stefan Ståhl, John Löfblom, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva
Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules. International journal of molecular sciences 21 (4) (2020)
Tianqi Xu, Haozhong Ding, Anzhelika Vorobyeva, Maryam Oroujeni, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund
Drug Conjugates Based on a Monovalent Affibody Targeting Vector Can Efficiently Eradicate HER2 Positive Human Tumors in an Experimental Mouse Model. Cancers 13 (1) (2020)
Anzhelika Vorobyeva, Ekaterina A Bezverkhniaia, Elena Konovalova, Alexey A Schulga, Javad Garousi, Olga Vorontsova, Ayman Abouzayed, Anna Orlova, Sergey Mikhailovich Deyev, Vladimir Tolmachev
Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1. Molecules (Basel, Switzerland) 25 (20) (2020)
Javad Garousi, Anzhelika Vorobyeva, Mohamed Altai
Influence of Several Compounds and Drugs on the Renal Uptake of Radiolabeled Affibody Molecules. Molecules (Basel, Switzerland) 25 (11) (2020)
Anzhelika Vorobyeva, Maryam Oroujeni, Sarah Lindbo, Sophia Hober, Tianqi Xu, Yongsheng Liu, Sara S Rinne, Javad Garousi
Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein. Molecules (Basel, Switzerland) 25 (19) (2020)
Mohamed Altai, Javad Garousi, Sara S Rinne, Alexey Schulga, Sergey Deyev, Anzhelika Vorobyeva
On the prevention of kidney uptake of radiolabeled DARPins. EJNMMI research 10 (1) (2020)
Anzhelika Vorobyeva, Elena Konovalova, Tianqi Xu, Alexey A Schulga, Mohamed Altai, Javad Garousi, Sara S Rinne, Anna Orlova, Vladimir Tolmachev, Sergey Deyev
Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1. International journal of molecular sciences 21 (9) (2020)
Charles Dahlsson Leitao, Sara S Rinne, Bogdan Mitran, Anzhelika Vorobyeva, Ken G Andersson, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova
Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers. International journal of molecular sciences 20 (5) (2019)
Javad Garousi, Fokko J Huizing, Anzhelika Vorobyeva, Bogdan Mitran, Ken G Andersson, Charles Dahlsson Leitao, Fredrik Y Frejd, John Löfblom, Johan Bussink, Anna Orlova, Sandra Heskamp, Vladimir Tolmachev
Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts. Scientific reports 9 (1) (2019)
Sergey Deyev, Anzhelika Vorobyeva, Alexey Schulga, Galina Proshkina, Rezan Güler, John Löfblom, Bogdan Mitran, Javad Garousi, Mohamed Altai, Jos Buijs, Vladimir Chernov, Anna Orlova, Vladimir Tolmachev
Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties. Molecular pharmaceutics 16 (3) (2019)
Maria Rosestedt, Ken G Andersson, Sara S Rinne, Charles Dahlsson Leitao, Bogdan Mitran, Anzhelika Vorobyeva, Stefan Ståhl, John Löfblom, Vladimir Tolmachev, Anna Orlova
Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake. Scientific reports 9 (1) (2019)
Anzhelika Vorobyeva, Alexey Schulga, Elena Konovalova, Rezan Güler, John Löfblom, Mattias Sandström, Javad Garousi, Vladimir Chernov, Olga Bragina, Anna Orlova, Vladimir Tolmachev, Sergey M Deyev
Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3. Scientific reports 9 (1) (2019)
Anzhelika Vorobyeva, Kristina Westerlund, Bogdan Mitran, Mohamed Altai, Sara Rinne, Jens Sörensen, Anna Orlova, Vladimir Tolmachev, Amelie Eriksson Karlström
Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy. Scientific reports 8 (1) (2018)
Anzhelika Vorobyeva, Olga Bragina, Mohamed Altai, Bogdan Mitran, Anna Orlova, Alexey Shulga, Galina Proshkina, Vladimir Chernov, Vladimir Tolmachev, Sergey Deyev
Comparative Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Radionuclide Molecular Imaging of HER2 Expression in Malignant Tumors. Contrast media & molecular imaging 2018 (2018)
Mohamed Altai, Charles Dahlsson Leitao, Sara S Rinne, Anzhelika Vorobyeva, Christina Atterby, Stefan Ståhl, Vladimir Tolmachev, John Löfblom, Anna Orlova
Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs. Cells 7 (10) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Anzhelika Vorobyeva