John R Ussher

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 40

Top Topics

Structural Basis

Skeletal Muscle

Top Venues

Journal of the American Heart Association

American journal of physiology. Cell physiology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Jordan S F Chan, John R Ussher
Vascular regeneration: a new mechanism of glucagon-like peptide-1 receptor agonist-mediated cardioprotection? American journal of physiology. Heart and circulatory physiology 327 (2) (2024)
Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Christina T Saed, Jordan S F Chan, Kunyan Yang, Indiresh A Mangra-Bala, Magnus J Stenlund, Farah Eaton, Keshav Gopal, Jason R B Dyck, Gary D Lopaschuk, John R Ussher
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy. Journal of the American Heart Association 13 (7) (2024)
John R Ussher, Ellen Aasum
The Relationship Between Cardiac Energy Metabolism and Cardiac Function in Obesity and Type 2 Diabetes: Revisiting a 2003 Diabetes Classic by Aasum et al. Diabetes 73 (9) (2024)
Kim L Ho, Qutuba Karwi, Faqi Wang, Cory Wagg, Liyan Zhang, Sai Panidarapu, Brandon Chen, Simran Pherwani, Amanda A Greenwell, Gavin Y Oudit, John R Ussher, Gary D Lopaschuk
The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischemic heart failure. Cardiovascular research (2024)
Kim L Ho, Qutuba Karwi, Faqi Wang, Cory Wagg, Liyan Zhang, Sai Panidarapu, Brandon Chen, Simran Pherwani, Amanda A Greenwell, Gavin Y Oudit, John R Ussher, Gary D Lopaschuk
The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischemic heart failure. Cardiovascular research (2024)
Yana Kibalnyk, Elia Afanasiev, Ronan M N Noble, Adrianne E S Watson, Irina Poverennaya, Nicole L Dittmann, Maria Alexiou, Kara Goodkey, Amanda A Greenwell, John R Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L Bourque, Jo Jo Anne Stratton, Anastassia Voronova
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function. Nature communications 15 (1) (2024)
Lisa C Heather, Keshav Gopal, Nikola Srnic, John R Ussher
Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology. Diabetes 73 (5) (2024)
Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Christina T Saed, Jordan S F Chan, Kunyan Yang, Indiresh A Mangra-Bala, Magnus J Stenlund, Farah Eaton, Keshav Gopal, Jason R B Dyck, Gary D Lopaschuk, John R Ussher
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy. Journal of the American Heart Association 13 (7) (2024)
Jordan S F Chan, Tanin Shafaati, John R Ussher
Incretin-mediated control of cardiac energy metabolism. The Journal of endocrinology 263 (1) (2024)
Shubham Soni, Seyed Amirhossein Tabatabaei Dakhili, John R Ussher, Jason R B Dyck
The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle. American journal of physiology. Cell physiology 326 (2) (2024)
Kim L Ho, Qutuba G Karwi, Faqi Wang, Cory Wagg, Liyan Zhang, Sai Panidarapu, Brandon Chen, Simran Pherwani, Amanda A Greenwell, Gavin Y Oudit, John R Ussher, Gary D Lopaschuk
The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischaemic heart failure. Cardiovascular research 120 (10) (2024)
Yana Kibalnyk, Elia Afanasiev, Ronan M N Noble, Adrianne E S Watson, Irina Poverennaya, Nicole L Dittmann, Maria Alexiou, Kara Goodkey, Amanda A Greenwell, John R Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L Bourque, Jo Jo Anne Stratton, Anastassia Voronova
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function. Nature communications 15 (1) (2024)
Shubham Soni, Seyed Amirhossein Tabatabaei Dakhili, John R Ussher, Jason R B Dyck
The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle. American journal of physiology. Cell physiology 326 (2) (2024)
Jordan S F Chan, Amanda A Greenwell, Christina T Saed, Magnus J Stenlund, Indiresh A Mangra-Bala, Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Sally R Ferrari, Farah Eaton, Keshav Gopal, John R Ussher
Liraglutide alleviates experimental diabetic cardiomyopathy in a PDH-dependent manner. The Journal of endocrinology 262 (2) (2024)
Kim L Ho, Qutuba G Karwi, Faqi Wang, Cory Wagg, Liyan Zhang, Sai Panidarapu, Brandon Chen, Simran Pherwani, Amanda A Greenwell, Gavin Y Oudit, John R Ussher, Gary D Lopaschuk
The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischaemic heart failure. Cardiovascular research 120 (10) (2024)
Yana Kibalnyk, Elia Afanasiev, Ronan M N Noble, Adrianne E S Watson, Irina Poverennaya, Nicole L Dittmann, Maria Alexiou, Kara Goodkey, Amanda A Greenwell, John R Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L Bourque, Jo Jo Anne Stratton, Anastassia Voronova
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function. Nature communications 15 (1) (2024)
Lisa C Heather, Keshav Gopal, Nikola Srnic, John R Ussher
Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology. Diabetes 73 (5) (2024)
Jordan S F Chan, John R Ussher
Vascular regeneration: a new mechanism of glucagon-like peptide-1 receptor agonist-mediated cardioprotection? American journal of physiology. Heart and circulatory physiology 327 (2) (2024)
Yana Kibalnyk, Elia Afanasiev, Ronan M N Noble, Adrianne E S Watson, Irina Poverennaya, Nicole L Dittmann, Maria Alexiou, Kara Goodkey, Amanda A Greenwell, John R Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L Bourque, Jo Jo Anne Stratton, Anastassia Voronova
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function. Nature communications 15 (1) (2024)
Shubham Soni, Seyed Amirhossein Tabatabaei Dakhili, John R Ussher, Jason R B Dyck
The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle. American journal of physiology. Cell physiology 326 (2) (2024)
Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Christina T Saed, Jordan S F Chan, Kunyan Yang, Indiresh A Mangra-Bala, Magnus J Stenlund, Farah Eaton, Keshav Gopal, Jason R B Dyck, Gary D Lopaschuk, John R Ussher
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy. Journal of the American Heart Association 13 (7) (2024)
Shubham Soni, Seyed Amirhossein Tabatabaei Dakhili, John R Ussher, Jason R B Dyck
The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle. American journal of physiology. Cell physiology 326 (2) (2024)
Hannah Khouri, Mathilde Roberge, John R Ussher, Céline Aguer
Acetoacetate and d- and l-β-hydroxybutyrate have distinct effects on basal and insulin-stimulated glucose uptake in L6 skeletal muscle cells. American journal of physiology. Cell physiology 326 (6) (2024)
Lisa C Heather, Keshav Gopal, Nikola Srnic, John R Ussher
Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of Its Pathology. Diabetes 73 (5) (2024)
Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Christina T Saed, Jordan S F Chan, Kunyan Yang, Indiresh A Mangra-Bala, Magnus J Stenlund, Farah Eaton, Keshav Gopal, Jason R B Dyck, Gary D Lopaschuk, John R Ussher
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy. Journal of the American Heart Association 13 (7) (2024)
Amanda A Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Christina T Saed, Jordan S F Chan, Kunyan Yang, Indiresh A Mangra-Bala, Magnus J Stenlund, Farah Eaton, Keshav Gopal, Jason R B Dyck, Gary D Lopaschuk, John R Ussher
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy. Journal of the American Heart Association (2024)
Jordan S F Chan, John R Ussher
Vascular regeneration: a new mechanism of glucagon-like peptide-1 receptor agonist-mediated cardioprotection? American journal of physiology. Heart and circulatory physiology 327 (2) (2024)
Hannah Khouri, Mathilde Roberge, John R Ussher, Céline Aguer
Acetoacetate and d- and l-β-hydroxybutyrate have distinct effects on basal and insulin-stimulated glucose uptake in L6 skeletal muscle cells. American journal of physiology. Cell physiology 326 (6) (2024)
John R Ussher, Daniel J Drucker
Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action. Nature reviews. Cardiology (2023)
Christina T Saed, Seyed Amirhossein Tabatabaei Dakhili, Amanda A Greenwell, Jordan S F Chan, Kunyan Yang, Keshav Gopal, Farah Eaton, Rami Al Batran, John R Ussher
The antianginal ranolazine fails to improve glycemia in obese liver-specific pyruvate dehydrogenase deficient male mice. Basic & clinical pharmacology & toxicology (2023)
Matthew D Martens, Claudia D Holody, Lisa Wells, Heidi L Silver, Daniela Y Morales-Llamas, William W Du, Courtney Reeks, Mostafa Khairy, Huachen Chen, Mourad Ferdaoussi, Stephane L Bourque, Burton B Yang, John R Ussher, Helene Lemieux, Gavin Y Oudit, Robert A Screaton, Jason R B Dyck
Reactive Oxygen Species Modulator 1 (ROMO1) Plays an Obligate Role in Cardiomyocyte Hypertrophy. Circulation research (2023)
John R Ussher, Amanda A Greenwell, My-Anh Nguyen, Erin E Mulvihill
Cardiovascular Effects of Incretin-Based Therapies: Integrating Mechanisms With Cardiovascular Outcome Trials. Diabetes 71 (2) (2022)
Seyed Amirhossein Tabatabaei Dakhili, Amanda A Greenwell, John R Ussher
Pyruvate Dehydrogenase Complex and Glucose Oxidation as a Therapeutic Target in Diabetic Heart Disease. Journal of lipid and atherosclerosis 12 (1) (2022)
Amanda A Greenwell, Christina T Saed, Seyed Amirhossein Tabatabaei Dakhili, Kim L Ho, Keshav Gopal, Jordan S F Chan, Oksana O Kaczmar, Scott A Dyer, Farah Eaton, Gary D Lopaschuk, Rami Al Batran, John R Ussher
An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice. American journal of physiology. Endocrinology and metabolism 323 (1) (2022)
Lisa C Heather, Anne D Hafstad, Ganesh V Halade, Romain Harmancey, Kimberley M Mellor, Paras Kumar Mishra, Erin E Mulvihill, Miranda Nabben, Michinari Nakamura, Oliver J Rider, Matthieu Ruiz, Adam R Wende, John R Ussher
Guidelines on models of diabetic heart disease. American journal of physiology. Heart and circulatory physiology 323 (1) (2022)
Jonathan E Campbell, Jacqueline L Beaudry, Berit Svendsen, Laurie L Baggio, Andrew N Gordon, John R Ussher, Chi Kin Wong, Fiona M Gribble, David A D'Alessio, Frank Reimann, Daniel J Drucker
GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue. Diabetes 71 (5) (2022)
Seyed Amirhossein Tabatabaei Dakhili, Amanda A Greenwell, John R Ussher
Pyruvate Dehydrogenase Complex and Glucose Oxidation as a Therapeutic Target in Diabetic Heart Disease. Journal of lipid and atherosclerosis 12 (1) (2022)
Jadin J Chahade, Ryekjang Kim, John R Ussher
Cardiovascular outcome trials in Type 2 diabetes: food for thought. Future cardiology 17 (3) (2021)
Yongneng Zhang, Sotirios D Zervopoulos, Aristeidis E Boukouris, Maria Areli Lorenzana-Carrillo, Bruno Saleme, Linda Webster, Yongsheng Liu, Alois Haromy, Seyed Amirhossein Tabatabaei Dakhili, John R Ussher, Gopinath Sutendra, Evangelos D Michelakis
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes. Journal of the American Heart Association 10 (23) (2021)
Amina Eshreif, Rami Al Batran, K Lockhart Jamieson, Ahmed M Darwesh, Keshav Gopal, Amanda A Greenwell, Igor Zlobine, Hanin Aburasayn, Farah Eaton, Erin E Mulvihill, Jonathan E Campbell, John M Seubert, John R Ussher
l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice. Experimental physiology 105 (2) (2020)