The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischaemic heart failure.

Kim L HoQutuba G KarwiFaqi WangCory WaggLiyan ZhangSai PanidarapuBrandon ChenSimran PherwaniAmanda A GreenwellGavin Y Oudit John R Ussher Gary D Lopaschuk

Published in: Cardiovascular research (2024)

We conclude that the ketogenic diet does not improve heart function in failing hearts, due to ketogenic diet-induced excessive fatty acid oxidation in the ischaemic heart and a decrease in insulin-stimulated glucose oxidation.

Keyphrases

heart failure
hydrogen peroxide
fatty acid
physical activity
weight loss
type diabetes
atrial fibrillation
blood glucose
electron transfer
left ventricular
visible light
weight gain
cardiac resynchronization therapy
body mass index