Jolanta Grembecka

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 10

Top Topics

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Transcription Factor

Top Venues

Nature communications

Nature chemical biology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Hongzhi Miao, Dong Chen, James Ropa, Trupta Purohit, EunGi Kim, Maria-Luisa Sulis, Adolfo A Ferrando, Tomasz Cierpicki, Jolanta Grembecka
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations. Leukemia 38 (8) (2024)
Hongzhi Miao, Dong Chen, James Ropa, Trupta Purohit, EunGi Kim, Maria-Luisa Sulis, Adolfo A Ferrando, Tomasz Cierpicki, Jolanta Grembecka
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations. Leukemia (2024)
Suzann Duan, Sulaiman Sheriff, Uloma B Elvis-Offiah, Brandon L Witten, Jennifer W Koevary, Sinju Sundaresan, Tomasz Cierpicki, Jolanta Grembecka, Juanita L Merchant
Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover. Cancer research communications 3 (7) (2023)
Xue Qing David Wang, Dandan Fan, Qinyu Han, Yiman Liu, Hongzhi Miao, Xinyu Wang, Qinglan Li, Dong Chen, Haley Gore, Pamela Himadewi, Gerd P Pfeifer, Tomasz Cierpicki, Jolanta Grembecka, Jianzhong Su, Shasha Chong, Liling Wan, Xiaotian Zhang
Mutant NPM1 hijacks transcriptional hub to maintain pathogenic gene programs in acute myeloid leukemia. Cancer discovery (2022)
Vladlena Kharchenko, Brian M Linhares, Megan Borregard, Iwona Czaban, Jolanta Grembecka, Mariusz Jaremko, Tomasz Cierpicki, Łukasz Jaremko
Increased slow dynamics defines ligandability of BTB domains. Nature communications 13 (1) (2022)
David S Rogawski, Jing Deng, Hao Li, Hongzhi Miao, Dmitry Borkin, Trupta Purohit, Jiho Song, Jennifer Chase, Shuangjiang Li, Juliano Ndoj, Szymon Klossowski, EunGi Kim, Fengbiao Mao, Bo Zhou, James Ropa, Marta Z Krotoska, Zhuang Jin, Patricia Ernst, Xiaomin Feng, Gang Huang, Kenichi Nishioka, Samantha Kelly, Miao He, Bo Wen, Duxin Sun, Andrew Muntean, Nils O Lindström, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nature communications 12 (1) (2021)
Shirish Shukla, Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L Simes, Qingjie Zhao, Hongzhi Miao, Hyo Je Cho, Paula González-Alonso, Alyssa Winkler, George Lund, Trupta Purohit, EunGi Kim, Xiaotian Zhang, Joshua M Ray, Shihan He, Caroline Nikolaidis, Juliano Ndoj, Jingya Wang, Łukasz Jaremko, Mariusz Jaremko, Russell J H Ryan, Monica L Guzman, Jolanta Grembecka, Tomasz Cierpicki
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nature chemical biology 17 (7) (2021)
Chunhua Wan, Sylvia Mahara, Claire Sun, Anh Doan, Hui Kheng Chua, Dakang Xu, Jia Bian, Yue Li, Danxi Zhu, Dhanya Sooraj, Tomasz Cierpicki, Jolanta Grembecka, Ron Firestein
Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer. Science advances 7 (21) (2021)
Brian M Linhares, Jolanta Grembecka, Tomasz Cierpicki
Targeting epigenetic protein-protein interactions with small-molecule inhibitors. Future medicinal chemistry 12 (14) (2020)
Dmitry Borkin, Szymon Klossowski, Jonathan Pollock, Hongzhi Miao, Brian M Linhares, Katarzyna Kempinska, Zhuang Jin, Trupta Purohit, Bo Wen, Miao He, Duxin Sun, Tomasz Cierpicki, Jolanta Grembecka
Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction. Journal of medicinal chemistry 61 (11) (2018)