Jonathan P Mochel (J P Mochel)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Venues

PloS one

Journal of veterinary pharmacology and therapeutics

Veterinary sciences

Veterinary ophthalmology

Iowa State University College of Veterinary Medicine

Universiteit Leiden (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Iowa State University College of Veterinary Medicine

United States

Associate Professor of Pharmacology :: Biomedical Sciences

F Hoffmann-La Roche AG

Switzerland

Franchise Leader :: Quantitative Systems Pharmacology

Novartis Pharma AG

Switzerland

Pharmacology Modeler :: Modeling and Simulation

Novartis AG

Switzerland

Resident :: Pharmacokinetics

Education History

Universiteit Leiden

Netherlands

PHD :: Pharmacology

Université Paul Sabatier Toulouse III UFR PCA

France

MSC

École Nationale Vétérinaire d'Alfort

France

PHD :: Veterinary Internal Medicine and Surgery

Université Paul Sabatier Toulouse III UFR PCA

France

MSC

Publications

Allison K Masters, Jessica L Ward, Emilie Guillot, Oliver Domenig, Lingnan Yuan, Jonathan P Mochel
Comprehensive characterization of the effect of mineralocorticoid receptor antagonism with spironolactone on the renin-angiotensin-aldosterone system in healthy dogs. PloS one 19 (2) (2024)
Allison K Masters, Jessica L Ward, Emilie Guillot, Oliver Domenig, Lingnan Yuan, Jonathan P Mochel
Comprehensive characterization of the effect of mineralocorticoid receptor antagonism with spironolactone on the renin-angiotensin-aldosterone system in healthy dogs. PloS one 19 (2) (2024)
Allison K Masters, Jessica L Ward, Emilie Guillot, Oliver Domenig, Lingnan Yuan, Jonathan P Mochel
Comprehensive characterization of the effect of mineralocorticoid receptor antagonism with spironolactone on the renin-angiotensin-aldosterone system in healthy dogs. PloS one 19 (2) (2024)
Siddhant Kothadiya, Gabriel Cutshaw, Saji Uthaman, Nora Hassan, Dipak Kumar Sahoo, Hannah Wickham, Elizabeth Quam, Karin Allenspach, Jonathan P Mochel, Rizia Bardhan
Cisplatin-Induced Metabolic Responses Measured with Raman Spectroscopy in Cancer Cells, Spheroids, and Canine-Derived Organoids. ACS applied materials & interfaces (2024)
Dipak Kumar Sahoo, Marilyn N Martinez, Kimberly Dao, Vojtech Gabriel, Christopher Zdyrski, Albert E Jergens, Todd Atherly, Chelsea A Iennarella-Servantez, Laura E Burns, Dwayne Schrunk, Donna A Volpe, Karin Allenspach, Jonathan P Mochel
Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study. Cells 12 (9) (2023)
David Díaz-Regañón, Vojtech Gabriel, Vanessa Livania, Dongjie Liu, Basant H Ahmed, Addison Lincoln, Hannah Wickham, Abigail Ralston, Maria M Merodio, Dipak Kumar Sahoo, Christopher Zdyrski, David K Meyerholz, Jonathan P Mochel, Karin Allenspach
Changes of Enterocyte Morphology and Enterocyte: Goblet Cell Ratios in Dogs with Protein-Losing and Non-Protein-Losing Chronic Enteropathies. Veterinary sciences 10 (7) (2023)
Karin Allenspach, Chi-Hsuan Sung, Jose Joaquin Ceron, Camila Peres Rubio, Agnes Bourgois-Mochel, Jan S Suchodolski, Lingnan Yuan, Debosmita Kundu, Joan Colom Comas, Kieran Rea, Jonathan P Mochel
Effect of the Probiotic Bacillus subtilis DE-CA9 TM on Fecal Scores, Serum Oxidative Stress Markers and Fecal and Serum Metabolome in Healthy Dogs. Veterinary sciences 10 (9) (2023)
Joseph Smith, Jessica E Gebert, Lisa S Ebner, Kailee O Bennett, Rebecca J Collins, Chiara E Hampton, Stephanie A Kleine, Pierre-Yves Mulon, Christopher K Smith, Reza Seddighi, Genevieve Bussieres, Jonathan P Mochel, Heather K Knych
Pharmacokinetics of intramuscular maropitant in pigs (Sus scrofa domesticus). Journal of veterinary pharmacology and therapeutics (2023)
Dipak Kumar Sahoo, Marilyn N Martinez, Kimberly Dao, Vojtech Gabriel, Christopher Zdyrski, Albert E Jergens, Todd Atherly, Chelsea A Iennarella-Servantez, Laura E Burns, Dwayne Schrunk, Donna A Volpe, Karin Allenspach, Jonathan P Mochel
Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study. Cells 12 (9) (2023)
Lauren E Page, Melissa A Kubai, Rachel Anne Allbaugh, Leila Bedos, Mackenzie M Roy, Jonathan P Mochel, Lionel Sebbag
Increased drug concentration and repeated eye drop administration as strategies to optimize topical drug delivery: A fluorophotometric study in healthy dogs. Veterinary ophthalmology (2023)
Dipak Kumar Sahoo, Marilyn N Martinez, Kimberly Dao, Vojtech Gabriel, Christopher Zdyrski, Albert E Jergens, Todd Atherly, Chelsea A Iennarella-Servantez, Laura E Burns, Dwayne Schrunk, Donna A Volpe, Karin Allenspach, Jonathan P Mochel
Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study. Cells 12 (9) (2023)
Margaret L Musser, Giovanna M Coto, Yuan Lingnan, Jonathan P Mochel, Chad M Johannes
Pilot safety evaluation of doxorubicin chemotherapy combined with non-specific immunotherapy (Immunocidin®) for canine splenic hemangiosarcoma. PloS one 17 (12) (2022)
Margaret L Musser, Giovanna M Coto, Yuan Lingnan, Jonathan P Mochel, Chad M Johannes
Pilot safety evaluation of doxorubicin chemotherapy combined with non-specific immunotherapy (Immunocidin®) for canine splenic hemangiosarcoma. PloS one 17 (12) (2022)
Margaret L Musser, Giovanna M Coto, Yuan Lingnan, Jonathan P Mochel, Chad M Johannes
Pilot safety evaluation of doxorubicin chemotherapy combined with non-specific immunotherapy (Immunocidin®) for canine splenic hemangiosarcoma. PloS one 17 (12) (2022)
Dipak Kumar Sahoo, Karin Allenspach, Jonathan P Mochel, Valerie Parker, Adam Joseph Rudinsky, Jenessa A Winston, Agnes Bourgois-Mochel, Mark Ackermann, Romy M Heilmann, Gabor Köller, Lingnan Yuan, Tracey Stewart, Shannon Morgan, Kaitlyn R Scheunemann, Chelsea A Iennarella-Servantez, Vojtech Gabriel, Christopher Zdyrski, Rachel Pilla, Jan S Suchodolski, Albert E Jergens
Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study. Veterinary sciences 10 (1) (2022)
Margaret L Musser, Giovanna M Coto, Yuan Lingnan, Jonathan P Mochel, Chad M Johannes
Pilot safety evaluation of doxorubicin chemotherapy combined with non-specific immunotherapy (Immunocidin®) for canine splenic hemangiosarcoma. PloS one 17 (12) (2022)
Margaret L Musser, Giovanna M Coto, Yuan Lingnan, Jonathan P Mochel, Chad M Johannes
Pilot safety evaluation of doxorubicin chemotherapy combined with non-specific immunotherapy (Immunocidin®) for canine splenic hemangiosarcoma. PloS one 17 (12) (2022)
Dipak Kumar Sahoo, Karin Allenspach, Jonathan P Mochel, Valerie Parker, Adam Joseph Rudinsky, Jenessa A Winston, Agnes Bourgois-Mochel, Mark Ackermann, Romy M Heilmann, Gabor Köller, Lingnan Yuan, Tracey Stewart, Shannon Morgan, Kaitlyn R Scheunemann, Chelsea A Iennarella-Servantez, Vojtech Gabriel, Christopher Zdyrski, Rachel Pilla, Jan S Suchodolski, Albert E Jergens
Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study. Veterinary sciences 10 (1) (2022)
Margaret L Musser, Giovanna M Coto, Yuan Lingnan, Jonathan P Mochel, Chad M Johannes
Pilot safety evaluation of doxorubicin chemotherapy combined with non-specific immunotherapy (Immunocidin®) for canine splenic hemangiosarcoma. PloS one 17 (12) (2022)
Dipak Kumar Sahoo, Karin Allenspach, Jonathan P Mochel, Valerie Parker, Adam Joseph Rudinsky, Jenessa A Winston, Agnes Bourgois-Mochel, Mark Ackermann, Romy M Heilmann, Gabor Köller, Lingnan Yuan, Tracey Stewart, Shannon Morgan, Kaitlyn R Scheunemann, Chelsea A Iennarella-Servantez, Vojtech Gabriel, Christopher Zdyrski, Rachel Pilla, Jan S Suchodolski, Albert E Jergens
Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study. Veterinary sciences 10 (1) (2022)
Dipak Kumar Sahoo, Karin Allenspach, Jonathan P Mochel, Valerie Parker, Adam Joseph Rudinsky, Jenessa A Winston, Agnes Bourgois-Mochel, Mark Ackermann, Romy M Heilmann, Gabor Köller, Lingnan Yuan, Tracey Stewart, Shannon Morgan, Kaitlyn R Scheunemann, Chelsea A Iennarella-Servantez, Vojtech Gabriel, Christopher Zdyrski, Rachel Pilla, Jan S Suchodolski, Albert E Jergens
Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study. Veterinary sciences 10 (1) (2022)
Michael Yaeger, Jonathan P Mochel, Zuowei Wu, Paul Plummer, Orhan Sahin, Joseph Smith, Melda Ocal, Ashenafi Beyi, Changyun Xu, Qijing Zhang, Ronald W Griffith
Pharmacokinetics of tulathromycin in pregnant ewes (Ovis aries) challenged with Campylobacter jejuni. PloS one 16 (8) (2021)
Marilyn N Martinez, Jonathan P Mochel, Sibylle Neuhoff, Devendra Pade
Comparison of Canine and Human Physiological Factors: Understanding Interspecies Differences that Impact Drug Pharmacokinetics. The AAPS journal 23 (3) (2021)
Sarah Minkler, Fabrice Lucien, Michael J Kimber, Dipak Kumar Sahoo, Agnes Bourgois-Mochel, Margaret Musser, Chad M Johannes, Igor Frank, John Cheville, Karin Allenspach, Jonathan P Mochel
Emerging Roles of Urine-Derived Components for the Management of Bladder Cancer: One Man's Trash Is Another Man's Treasure. Cancers 13 (3) (2021)
Morgan Bertram, Rachel Anne Allbaugh, Jonathan P Mochel, Jacqueline Peraza, Lauren E Page, Lionel Sebbag
Influence of Schirmer strip wetness on volume absorbed, volume recovered, and total protein content in canine tears. Veterinary ophthalmology 24 (4) (2021)
Cristina Vaghi, Anne Rodallec, Raphaëlle Fanciullino, Joseph Ciccolini, Jonathan P Mochel, Michalis Mastri, Clair Poignard, John M L Ebos, Sebastien Benzekry
Population modeling of tumor growth curves and the reduced Gompertz model improve prediction of the age of experimental tumors. PLoS computational biology 16 (2) (2020)
Lionel Sebbag, Jonathan P Mochel
An eye on the dog as the scientist's best friend for translational research in ophthalmology: Focus on the ocular surface. Medicinal research reviews 40 (6) (2020)
Lionel Sebbag, Elizabeth A Soler, Rachel Anne Allbaugh, Jonathan P Mochel
Impact of acute conjunctivitis on ocular surface homeostasis in dogs. Veterinary ophthalmology 23 (5) (2020)
Yoko M Ambrosini, Yejin Park, Albert E Jergens, Woojung Shin, Soyoun Min, Todd Atherly, Dana C Borcherding, Jinah Jang, Karin Allenspach, Jonathan P Mochel, Hyun Jung Kim
Recapitulation of the accessible interface of biopsy-derived canine intestinal organoids to study epithelial-luminal interactions. PloS one 15 (4) (2020)
Hannah M Terhaar, Rachel Anne Allbaugh, Jonathan P Mochel, Lionel Sebbag
Serum albumin and total protein concentration in the tear film of horses with healthy or diseased eyes. Veterinary ophthalmology 24 (1) (2020)
Lauren E Page, Rachel Anne Allbaugh, Jonathan P Mochel, Jacqueline Peraza, Morgan Bertram, Lionel Sebbag
Impact of diurnal variation, sex, tear collection method, and disease state on tear protein levels in dogs. Veterinary ophthalmology 23 (6) (2020)
Joseph Smith, Jonathan P Mochel, David J Borts, Ronald W Griffith
Effects of experimentally induced respiratory disease on the pharmacokinetics and tissue residues of tulathromycin in meat goats. Journal of veterinary pharmacology and therapeutics 42 (4) (2019)
Todd Atherly, Giacomo Rossi, Robin White, Yeon-Jung Seo, Chong Wang, Mark Ackermann, Mary Breuer, Karin Allenspach, Jonathan P Mochel, Albert E Jergens
Glucocorticoid and dietary effects on mucosal microbiota in canine inflammatory bowel disease. PloS one 14 (12) (2019)
Lionel Sebbag, Leah M Moody, Rachel Anne Allbaugh, Jonathan P Mochel
Nerve growth factor in dogs: Assessment of two immunoassays and selected ocular parameters following a nicergoline challenge per os. Veterinary ophthalmology 23 (1) (2019)
Jianzhong Wang, Benjamin K Schneider, Pan Sun, Xiaohui Gong, Jicheng Qiu, Jing Li, Yeon-Jung Seo, Jonathan P Mochel, Xingyuan Cao
Nonlinear mixed-effects pharmacokinetic modeling of the novel COX-2 selective inhibitor vitacoxib in dogs. Journal of veterinary pharmacology and therapeutics 42 (5) (2019)
Joseph Smith, J F Coetzee, I W G Fisher, D J Borts, Jonathan P Mochel
Pharmacokinetics of fentanyl citrate and norfentanyl in Holstein calves and effect of analytical performances on fentanyl parameter estimation. Journal of veterinary pharmacology and therapeutics 41 (4) (2018)
Patrick J Gorden, Joshua A Ydstie, Michael D Kleinhenz, Troy A Brick, Joseph Smith, Ronald W Griffith, Larry W Wulf, Suzanne M Rajewski, Min Zhang, Pritam K Sidhu, Jonathan P Mochel, Johann F Coetzee
Comparative plasma and interstitial fluid pharmacokinetics and tissue residues of ceftiofur crystalline-free acid in cattle with induced coliform mastitis. Journal of veterinary pharmacology and therapeutics 41 (6) (2018)
Patrick J Gorden, M Burchard, J A Ydstie, Michael D Kleinhenz, L W Wulf, S J Rajewski, C Wang, Ronette Gehring, Jonathan P Mochel, J F Coetzee
Comparison of milk and plasma pharmacokinetics of meloxicam in postpartum versus mid-lactation Holstein cows. Journal of veterinary pharmacology and therapeutics 41 (3) (2018)
Erika P Berger, Chad M Johannes, Albert E Jergens, Karin Allenspach, Barbara E Powers, Yingzhou Du, Jonathan P Mochel, Leslie E Fox, Margaret L Musser
Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of gastrointestinal stromal tumors of dogs. Journal of veterinary internal medicine 32 (6) (2018)
Marilyn N Martinez, Ronette Gehring, Jonathan P Mochel, Devendra Pade, Ludovic Pelligand
Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation. Journal of veterinary pharmacology and therapeutics 41 (4) (2018)
C Bon, Pierre-Louis Toutain, D Concordet, Ronette Gehring, T Martin-Jimenez, J Smith, L Pelligand, Marilyn N Martinez, T Whittem, J E Riviere, Jonathan P Mochel
Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics. Journal of veterinary pharmacology and therapeutics 41 (2) (2017)
Jonathan P Mochel, E Tyden, K Hellmann, J C Vendrig, S Şenel, L Dencker, R T Cristina, H Linden, I Schmerold
Network on veterinary medicines initiated by the European Federation For Pharmaceutical Sciences. Journal of veterinary pharmacology and therapeutics 41 (3) (2017)

Jonathan P Mochel.css-eqlu8i{font-size:small;padding-left:4px;} (J P Mochel)

Publication Activity (10 Years)

Top Topics

Top Venues

Jonathan P Mochel (J P Mochel)