Kai Ge

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 18

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Molecular and cellular biology

Molecular cancer research : MCR

National Institutes of Health

Shanghai Institute of Biochemistry, Chinese Academy of Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institutes of Health

United States

Senior Investigator and Section Chief :: NIDDK

National Institutes of Health

United States

Tenure Track Investigator :: NIDDK

Rockefeller University

United States

Postdoctoral Fellow :: Robert Roeder Lab

Wistar Institute

United States

Postdoctoral Fellow :: George Prendergast Lab

Education History

Shanghai Institute of Biochemistry, Chinese Academy of Sciences

China

PHD

Fudan University

China

BSC :: Department of Biochemistry

Publications

Guojia Xie, Ji-Eun Lee, Anna D Senft, Young-Kwon Park, Younghoon Jang, Shreeta Chakraborty, Joyce J Thompson, Kaitlin McKernan, Chengyu Liu, Todd S Macfarlan, Pedro P Rocha, Weiqun Peng, Kai Ge
MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner. Nature genetics (2023)
Rachel E Musa, Kaitlyn L Lester, Gabrielle A Quickstad, Sara Vardabasso, Trevor V Shumate, Ryan T Salcido, Kai Ge, Karl B Shpargel
BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation. Development (Cambridge, England) (2023)
Haobin Chen, Lisa Gesumaria, Young-Kwon Park, Trudy G Oliver, Dinah S Singer, Kai Ge, David S Schrump
BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation. Molecular cancer research : MCR (2022)
Kiran Nakka, Sarah Hachmer, Zeinab Mokhtari, Radmila Kovac, Hina Bandukwala, Clara Bernard, Yuefeng Li, Guojia Xie, Chengyu Liu, Magid Fallahi, Lynn Arthur Megeney, Julien Gondin, Bénédicte Chazaud, Marjorie Brand, Xiaohui Zha, Kai Ge, F Jeffrey Dilworth
JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment. Science (New York, N.Y.) 377 (6606) (2022)
Young-Kwon Park, Ji-Eun Lee, Zhijiang Yan, Kaitlin McKernan, Tommy O'Haren, Weidong Wang, Weiqun Peng, Kai Ge
Interplay of BAF and MLL4 promotes cell type-specific enhancer activation. Nature communications 12 (1) (2021)
Shaun Egolf, Jonathan Zou, Amy Anderson, Cory L Simpson, Yann Aubert, Stephen M Prouty, Kai Ge, John T Seykora, Brian C Capell
MLL4 mediates differentiation and tumor suppression through ferroptosis. Science advances 7 (50) (2021)
Younghoon Jang, Young-Kwon Park, Ji-Eun Lee, Danyang Wan, Nhien V Tran, Oksana Gavrilova, Kai Ge
MED1 is a lipogenesis coactivator required for postnatal adipose expansion. Genes & development 35 (9-10) (2021)
Ji-Eun Lee, Young-Wook Cho, Chu-Xia Deng, Kai Ge
MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ. Molecular and cellular biology 40 (17) (2020)
Nhien V Tran, Aaron Broun, Kai Ge
Lysine Demethylase KDM6A in Differentiation, Development, and Cancer. Molecular and cellular biology 40 (20) (2020)
Kazushige Ota, Akiyoshi Komuro, Hisayuki Amano, Akinori Kanai, Kai Ge, Takeshi Ueda, Hitoshi Okada
High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase. Scientific reports 9 (1) (2019)
Ji-Eun Lee, Hannah Schmidt, Binbin Lai, Kai Ge
Transcriptional and Epigenomic Regulation of Adipogenesis. Molecular and cellular biology 39 (11) (2019)
Yi Zhang, Younghoon Jang, Ji-Eun Lee, JaeWoo Ahn, Longxia Xu, Michael R Holden, Evan M Cornett, Krzysztof Krajewski, Brianna J Klein, Shu-Ping Wang, Yali Dou, Robert G Roeder, Brian D Strahl, Scott B Rothbart, Xiaobing Shi, Kai Ge, Tatiana G Kutateladze
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature communications 10 (1) (2019)
Lenan Zhuang, Younghoon Jang, Young-Kwon Park, Ji-Eun Lee, Shalini Jain, Eugene Froimchuk, Aaron Broun, Chengyu Liu, Oksana Gavrilova, Kai Ge
Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function. Nature communications 9 (1) (2018)
Prosun Das, Kylee J Veazey, Hieu T Van, Saakshi Kaushik, Kevin Lin, Yue Lu, Masaru Ishii, Junichi Kikuta, Kai Ge, Andre Nussenzweig, Margarida A Santos
Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches. Proceedings of the National Academy of Sciences of the United States of America 115 (43) (2018)
Qibiao Wu, Yahui Tian, Jian Zhang, Xinyuan Tong, Hsinyi Huang, Shuai Li, Hong Zhao, Ying Tang, Chongze Yuan, Kun Wang, Zhaoyuan Fang, Lei Gao, Xin Hu, Fuming Li, Zhen Qin, Shun Yao, Ting Chen, Haiquan Chen, Gong Zhang, Wanting Liu, Yihua Sun, Luonan Chen, Kwok-Kin Wong, Kai Ge, Liang Chen, Hongbin Ji
In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America 115 (17) (2018)
Karl B Shpargel, Joshua Starmer, Chaochen Wang, Kai Ge, Terry R Magnuson
UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome. Proceedings of the National Academy of Sciences of the United States of America 114 (43) (2017)
Ji-Eun Lee, Young-Kwon Park, Sarah Park, Younghoon Jang, Nicholas Waring, Anup Dey, Keiko Ozato, Binbin Lai, Weiqun Peng, Kai Ge
Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis. Nature communications 8 (1) (2017)
Chaochen Wang, Ji-Eun Lee, Binbin Lai, Todd S Macfarlan, Shiliyang Xu, Lenan Zhuang, Chengyu Liu, Weiqun Peng, Kai Ge
Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition. Proceedings of the National Academy of Sciences of the United States of America 113 (42) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kai Ge