Scott B Rothbart

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 16

Top Topics

Intellectual Disability

Dna Methylation

Top Venues

Science advances

The Journal of biological chemistry

Proceedings of the National Academy of Sciences of the United States of America

The Biochemical journal

This page only lists publications with an associated author ORCID identifier.

Publications

Alison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, Xiangqian Kong, Ying Cui, Ashley K Wiseman, Katherine E Thurlow, Evan M Cornett, Michael J Topper, Stephen B Baylin, Scott B Rothbart
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling. Science advances 10 (13) (2024)
Alison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, Xiangqian Kong, Ying Cui, Ashley K Wiseman, Katherine E Thurlow, Evan M Cornett, Michael J Topper, Stephen B Baylin, Scott B Rothbart
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling. Science advances 10 (13) (2024)
Alison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, Xiangqian Kong, Ying Cui, Ashley K Wiseman, Katherine E Thurlow, Evan M Cornett, Michael J Topper, Stephen B Baylin, Scott B Rothbart
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling. Science advances 10 (13) (2024)
Alison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, Xiangqian Kong, Ying Cui, Ashley K Wiseman, Katherine E Thurlow, Evan M Cornett, Michael J Topper, Stephen B Baylin, Scott B Rothbart
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling. Science advances 10 (13) (2024)
Alison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, Xiangqian Kong, Ying Cui, Ashley K Wiseman, Katherine E Thurlow, Evan M Cornett, Michael J Topper, Stephen B Baylin, Scott B Rothbart
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling. Science advances 10 (13) (2024)
Eric Cordeiro-Spinetti, Scott B Rothbart
Lysine methylation signaling in skeletal muscle biology: from myogenesis to clinical insights. The Biochemical journal 480 (23) (2023)
Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, Michael J Emanuele
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators. PLoS biology 18 (12) (2020)
Anja Armache, Shuang Yang, Alexia Martínez de Paz, Lexi E Robbins, Ceyda Durmaz, Jin Q Cheong, Steven Z Josefowicz, Andrew W Daman, Dughan J Ahimovic, Thaís Klevorn, Yuan Yue, Tanja Arslan, Shu Lin, Tanya Panchenko, Joel Hrit, Miao Wang, Samuel Thudium, Benjamin A Garcia, Erica Korb, Karim-Jean Armache, Scott B Rothbart, Sandra B Hake, C David Allis, Haitao Li, Steven Zvi Josefowicz
Histone H3.3 phosphorylation amplifies stimulation-induced transcription. Nature 583 (7818) (2020)
Robert M Vaughan, Ariana Kupai, Caroline A Foley, Cari A Sagum, Bailey M Tibben, Hope E Eden, Rochelle L Tiedemann, Christine A Berryhill, Varun Patel, Kevin M Shaw, Krzysztof Krajewski, Brian D Strahl, Mark T Bedford, Stephen V Frye, Bradley M Dickson, Scott B Rothbart
The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells. Epigenetics & chromatin 13 (1) (2020)
Matt L Harlow, Maggie H Chasse, Elissa A Boguslawski, Katie M Sorensen, Jenna M Gedminas, Susan M Kitchen-Goosen, Scott B Rothbart, Cenny Taslim, Stephen L Lessnick, Anderson S Peck, Zachary B Madaj, Megan J Bowman, Patrick J Grohar
Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (11) (2019)
Robert M Vaughan, Scott B Rothbart, Bradley M Dickson
The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation. The Journal of biological chemistry 294 (43) (2019)
C Jake Harris, Marion Scheibe, Somsakul Pop Wongpalee, Wanlu Liu, Evan M Cornett, Robert M Vaughan, Xueqin Li, Wei Chen, Yan Xue, Zhenhui Zhong, Linda Yen, William D Barshop, Shima Rayatpisheh, Javier Gallego-Bartolome, Martin Groth, Zonghua Wang, James Akira Wohlschlegel, Jiamu Du, Scott B Rothbart, Falk Butter, Steven E Jacobsen
A DNA methylation reader complex that enhances gene transcription. Science (New York, N.Y.) 362 (6419) (2019)
Yi Zhang, Younghoon Jang, Ji-Eun Lee, JaeWoo Ahn, Longxia Xu, Michael R Holden, Evan M Cornett, Krzysztof Krajewski, Brianna J Klein, Shu-Ping Wang, Yali Dou, Robert G Roeder, Brian D Strahl, Scott B Rothbart, Xiaobing Shi, Kai Ge, Tatiana G Kutateladze
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature communications 10 (1) (2019)
Robert M Vaughan, Bradley M Dickson, Matthew F Whelihan, Andrea L Johnstone, Evan M Cornett, Marcus A Cheek, Christine A Ausherman, Martis W Cowles, Zu-Wen Sun, Scott B Rothbart
Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1. Proceedings of the National Academy of Sciences of the United States of America 115 (35) (2018)
Evan M Cornett, Bradley M Dickson, Krzysztof Krajewski, Nicholas Spellmon, Andrew Umstead, Robert M Vaughan, Kevin M Shaw, Philip P Versluis, Martis W Cowles, Joseph Brunzelle, Zhe Yang, Irving E Vega, Zu-Wen Sun, Scott B Rothbart
A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity. Science advances 4 (11) (2018)
Joseph S Harrison, Evan M Cornett, Dennis Goldfarb, Paul A DaRosa, Zimeng M Li, Feng Yan, Bradley M Dickson, Angela H Guo, Daniel V Cantu, Lilia Kaustov, Peter J Brown, Cheryl H Arrowsmith, Dorothy A Erie, Michael B Major, Rachel E Klevit, Krzysztof Krajewski, Brian Kuhlman, Brian D Strahl, Scott B Rothbart
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. eLife 5 (2016)