Keefe T Chan

ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 6

Top Venues

The EMBO journal

British journal of cancer

eLife

Cell death and differentiation

Peter Mac at the Victorian Comprehensive Cancer Centre

University of Wisconsin Madison (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Peter Mac at the Victorian Comprehensive Cancer Centre Aug 25 2014

Australia

Research Officer :: Division of Cancer Research

University of North Carolina Aug 15 2010 - Aug 15 2014

United States

Postdoctoral Research Associate :: Cell Biology and Physiology

Education History

University of Wisconsin Madison Aug 15 2004 - May 28 2010

United States

PHD :: Molecular and Cellular Pharmacology

University of California Berkeley Aug 15 1999 - May 15 2003

United States

BSC :: Bioengineering

Publications

Catherine Dietrich, Alec Trub, Antonio Ahn, Michael Taylor, Krutika Ambani, Keefe T Chan, Kun-Hui Lu, Christabella A Mahendra, Catherine Blyth, Rhiannon Coulson, Susanne Ramm, April C Watt, Sunil Kumar Matsa, John E Bisi, Jay Strum, Patrick Roberts, Shom Goel
INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors. Cancer discovery (2023)
Haoran Zhu, Keefe T Chan, Xinran Huang, Carmelo Cerra, Shaun Blake, Anna Sofia Trigos, Dovile Anderson, Darren J Creek, David P De Souza, Xi Wang, Caiyun Fu, Metta Jana, Elaine Sanij, Richard B Pearson, Jian Kang
Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation. eLife 11 (2022)
Elaine Sanij, Katherine M Hannan, Jiachen Xuan, Shunfei Yan, Jessica E Ahern, Anna Sofia Trigos, Natalie Brajanovski, Jinbae Son, Keefe T Chan, Olga Kondrashova, Elizabeth Lieschke, Matthew J Wakefield, Daniel Frank, Sarah L Ellis, Carleen Cullinane, Jian Kang, Gretchen Poortinga, Purba Nag, Andrew J Deans, Kum Kum Khanna, Linda Mileshkin, Grant A McArthur, John Soong, Els M J J Berns, Ross D Hannan, Clare L Scott, Karen E Sheppard, Richard B Pearson
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer. Nature communications 11 (1) (2020)
Shunfei Yan, Jiachen Xuan, Natalie Brajanovski, Madeleine R C Tancock, Piyush B Madhamshettiwar, Kaylene J Simpson, Sarah L Ellis, Jian Kang, Carleen Cullinane, Karen E Sheppard, Katherine M Hannan, Ross D Hannan, Elaine Sanij, Richard B Pearson, Keefe T Chan
The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer. British journal of cancer 124 (3) (2020)
Eric P Kusnadi, Anna Sofia Trigos, Carleen Cullinane, David L Goode, Ola Larsson, Jennifer R Devlin, Keefe T Chan, David P De Souza, Malcolm J McConville, Grant A McArthur, George Thomas, Elaine Sanij, Gretchen Poortinga, Ross D Hannan, Katherine M Hannan, Jian Kang, Richard B Pearson
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis. The EMBO journal 39 (21) (2020)
Keefe T Chan, Shaun Blake, Haoran Zhu, Jian Kang, Anna S Trigos, Piyush B Madhamshettiwar, Jeannine Diesch, Lassi Paavolainen, Peter Horvath, Ross D Hannan, Amee J George, Elaine Sanij, Katherine M Hannan, Kaylene J Simpson, Richard B Pearson
A functional genetic screen defines the AKT-induced senescence signaling network. Cell death and differentiation 27 (2) (2019)

Keefe T Chan.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Keefe T Chan