Richard B Pearson

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 18

Top Venues

Nature communications

Cell death and differentiation

Oncogene

The EMBO journal

This page only lists publications with an associated author ORCID identifier.

Publications

Yuzhou Feng, Tianpei Yang, John Zhu, Mabel Li, Maria Doyle, Volkan Ozcoban, Greg T Bass, Angela Pizzolla, Lachlan Cain, Sirui Weng, Anupama Pasam, Nikolce Kocovski, Yu-Kuan Huang, Simon Paul Keam, Terence P Speed, Paul Joseph Neeson, Richard B Pearson, Shahneen Sandhu, David L Goode, Anna Sofia Trigos
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments. Nature communications 14 (1) (2023)
Yuzhou Feng, Tianpei Yang, John Zhu, Mabel Li, Maria Doyle, Volkan Ozcoban, Greg T Bass, Angela Pizzolla, Lachlan Cain, Sirui Weng, Anupama Pasam, Nikolce Kocovski, Yu-Kuan Huang, Simon Paul Keam, Terence P Speed, Paul Joseph Neeson, Richard B Pearson, Shahneen Sandhu, David L Goode, Anna Sofia Trigos
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments. Nature communications 14 (1) (2023)
Yuzhou Feng, Tianpei Yang, John Zhu, Mabel Li, Maria Doyle, Volkan Ozcoban, Greg T Bass, Angela Pizzolla, Lachlan Cain, Sirui Weng, Anupama Pasam, Nikolce Kocovski, Yu-Kuan Huang, Simon Paul Keam, Terence P Speed, Paul Joseph Neeson, Richard B Pearson, Shahneen Sandhu, David L Goode, Anna Sofia Trigos
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments. Nature communications 14 (1) (2023)
Lorey K Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P Kusnadi, Jian Kang, Claire A Martin, Peter Kar Han Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Sofia Trigos, Teresa Ward, Aparna D Rao, Emily J Lelliott, Karen E Sheppard, David Goode, Rodney John Hicks, Tony Tiganis, Kaylene J Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O Wickramasinghe, Richard B Pearson, Grant A McArthur
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF V600 melanoma. Nature communications 13 (1) (2022)
Haoran Zhu, Keefe T Chan, Xinran Huang, Carmelo Cerra, Shaun Blake, Anna Sofia Trigos, Dovile Anderson, Darren J Creek, David P De Souza, Xi Wang, Caiyun Fu, Metta Jana, Elaine Sanij, Richard B Pearson, Jian Kang
Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation. eLife 11 (2022)
Katarzyna Koltowska, Kazuhide S Okuda, Marleen Gloger, Maria Rondon-Galeano, Elizabeth A Mason, Jiachen Xuan, Stefanie Dudczig, Huijun Chen, Hannah Arnold, Renae Skoczylas, Neil I Bower, Scott Paterson, Anne Karine Lagendijk, Gregory J Baillie, Ignaty Leshchiner, Cas Simons, Kelly A Smith, Wolfram Goessling, Joan Kathleen Heath, Richard B Pearson, Elaine Sanij, Stefan Schulte-Merker, Benjamin M Hogan
The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function. Nature cell biology 23 (11) (2021)
Mitchell G Lawrence, Laura H Porter, Nicholas Choo, David W Pook, Jeremy P Grummet, Carmel J Pezaro, Shahneen Sandhu, Susanne Ramm, Jennii Luu, Andrew Bakshi, David L Goode, Elaine Sanij, Richard B Pearson, Ross D Hannan, Kaylene J Simpson, Renea A Taylor, Gail P Risbridger, Luc Furic
CX-5461 Sensitizes DNA Damage Repair-proficient Castrate-resistant Prostate Cancer to PARP Inhibition. Molecular cancer therapeutics 20 (11) (2021)
Elaine Sanij, Katherine M Hannan, Jiachen Xuan, Shunfei Yan, Jessica E Ahern, Anna Sofia Trigos, Natalie Brajanovski, Jinbae Son, Keefe T Chan, Olga Kondrashova, Elizabeth Lieschke, Matthew J Wakefield, Daniel Frank, Sarah L Ellis, Carleen Cullinane, Jian Kang, Gretchen Poortinga, Purba Nag, Andrew J Deans, Kum Kum Khanna, Linda Mileshkin, Grant A McArthur, John Soong, Els M J J Berns, Ross D Hannan, Clare L Scott, Karen E Sheppard, Richard B Pearson
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer. Nature communications 11 (1) (2020)
Shunfei Yan, Jiachen Xuan, Natalie Brajanovski, Madeleine R C Tancock, Piyush B Madhamshettiwar, Kaylene J Simpson, Sarah L Ellis, Jian Kang, Carleen Cullinane, Karen E Sheppard, Katherine M Hannan, Ross D Hannan, Elaine Sanij, Richard B Pearson, Keefe T Chan
The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer. British journal of cancer 124 (3) (2020)
Eric P Kusnadi, Anna Sofia Trigos, Carleen Cullinane, David L Goode, Ola Larsson, Jennifer R Devlin, Keefe T Chan, David P De Souza, Malcolm J McConville, Grant A McArthur, George Thomas, Elaine Sanij, Gretchen Poortinga, Ross D Hannan, Katherine M Hannan, Jian Kang, Richard B Pearson
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis. The EMBO journal 39 (21) (2020)
Jixuan Gao, MoonSun Jung, Chelsea Mayoh, Pooja Venkat, Katherine M Hannan, Jamie I Fletcher, Alvin Kamili, Andrew J Gifford, Eric P Kusnadi, Richard B Pearson, Ross D Hannan, Michelle Haber, Murray D Norris, Klaartje Somers, Michelle J Henderson
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression. Cancer research 80 (17) (2020)
Amit Khot, Natalie Brajanovski, Donald P Cameron, Nadine Hein, Kylee H Maclachlan, Elaine Sanij, John Lim, John Soong, Emma Link, Piers Blombery, Ella R Thompson, Andrew Fellowes, Karen E Sheppard, Grant A McArthur, Richard B Pearson, Ross D Hannan, Gretchen Poortinga, Simon James Harrison
First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study. Cancer discovery 9 (8) (2019)
Keefe T Chan, Shaun Blake, Haoran Zhu, Jian Kang, Anna S Trigos, Piyush B Madhamshettiwar, Jeannine Diesch, Lassi Paavolainen, Peter Horvath, Ross D Hannan, Amee J George, Elaine Sanij, Katherine M Hannan, Kaylene J Simpson, Richard B Pearson
A functional genetic screen defines the AKT-induced senescence signaling network. Cell death and differentiation 27 (2) (2019)
Jeannine Diesch, Megan J Bywater, Elaine Sanij, Donald P Cameron, William Schierding, Natalie Brajanovski, Jinbae Son, Jirawas Sornkom, Nadine Hein, Maurits Evers, Richard B Pearson, Grant A McArthur, Austen R D Ganley, Justin Martin O'Sullivan, Ross D Hannan, Gretchen Poortinga
Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation. Communications biology 2 (2019)
Klaartje Somers, Victoria W Wen, Shiloh M C Middlemiss, Brenna Osborne, Helen Forgham, MoonSun Jung, Mawar Karsa, Molly Clifton, Angelika Bongers, Jixuan Gao, Chelsea Mayoh, Newsha Raoufi-Rad, Eric P Kusnadi, Kate M Hannan, David A Scott, Alan Kwek, Bing Liu, Claudia Flemming, Daria A Chudakova, Ruby Pandher, Tim W Failes, James Lim, Andrea Angeli, Andrei L Osterman, Toshihiko Imamura, Ursula R Kees, Claudiu T Supuran, Richard B Pearson, Ross D Hannan, Thomas P Davis, Joshua McCarroll, Maria Kavallaris, Nigel Turner, Andrei V Gudkov, Michelle Haber, Murray D Norris, Michelle J Henderson
A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene 38 (20) (2019)
Olga Kondrashova, Monique Topp, Ksenija Nesic, Elizabeth Lieschke, Gwo-Yaw Ho, Maria I Harrell, Giada V Zapparoli, Alison Hadley, Robert Holian, Emma Boehm, Valerie Heong, Elaine Sanij, Richard B Pearson, John J Krais, Neil Johnson, Orla McNally, Sumitra Ananda, Kathryn Alsop, Karla J Hutt, Scott H Kaufmann, Kevin K Lin, Thomas C Harding, Nadia Traficante, null null, Anna deFazio, Iain A McNeish, David D Bowtell, Elizabeth M Swisher, Alexander Dobrovic, Matthew J Wakefield, Clare L Scott
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. Nature communications 9 (1) (2018)
Haoran Zhu, Shaun Blake, Keefe T Chan, Richard B Pearson, Jian Kang
Cystathionine β-Synthase in Physiology and Cancer. BioMed research international 2018 (2018)
Charbel Darido, Smitha R Georgy, Carleen Cullinane, Darren D Partridge, Rachael Walker, Seema Srivastava, Suraya Roslan, Marina R Carpinelli, Sebastian Dworkin, Richard B Pearson, Stephen M Jane
Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin. Cell death and differentiation 25 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Richard B Pearson