Kevin C O'Connor

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Science immunology

Nature biotechnology

Annals of clinical and translational neurology

Yale University School of Medicine

Tufts University School of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Yale University School of Medicine

United States

Associate Professor :: Neurology

Harvard Medical School

United States

Assistant Professor :: Neurology

Brigham and Women's Hospital

United States

Associate Scientist :: Center for Neurologic Diseases, Department of Neurology

Tufts University School of Medicine

United States

Adjunct Lecturer

Brigham and Women's Hospital

United States

Research Associate :: Center for Neurologic Diseases, Neurology

Harvard Medical School

United States

Instructor in Neurology

Ares-Serono Pharmaceuticals

United States

Associate Scientist

Waters Chromatography Div. of Millipore

United States

Applications Chemist

Education History

Tufts University School of Medicine

United States

PHD :: Biochemistry

University of Massachusetts Amherst

United States

BSC :: Chemistry

Publications

Soumya S Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L Bennett, Richard J Nowak, Elias S Sotirchos, Erin E Longbrake, Emily M Mace, Kevin C O'Connor
A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases. Journal of immunology (Baltimore, Md. : 1950) (2024)
Soumya S Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L Bennett, Richard J Nowak, Elias S Sotirchos, Erin E Longbrake, Emily M Mace, Kevin C O'Connor
A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases. Journal of immunology (Baltimore, Md. : 1950) (2024)
Soumya S Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L Bennett, Richard J Nowak, Elias S Sotirchos, Erin E Longbrake, Emily M Mace, Kevin C O'Connor
A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases. Journal of immunology (Baltimore, Md. : 1950) 212 (5) (2024)
Soumya S Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L Bennett, Richard J Nowak, Elias S Sotirchos, Erin E Longbrake, Emily M Mace, Kevin C O'Connor
A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases. Journal of immunology (Baltimore, Md. : 1950) 212 (5) (2024)
Annabel Wallace, Kevin C O'Connor
Hide-&-Go-PhiP-Seq: Finding an elusive predictive MS biomarker. Science immunology 9 (96) (2024)
Soumya S Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L Bennett, Richard J Nowak, Elias S Sotirchos, Erin E Longbrake, Emily M Mace, Kevin C O'Connor
A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases. Journal of immunology (Baltimore, Md. : 1950) (2024)
Soumya S Yandamuri, Beata Filipek, Nikhil Lele, Inessa Cohen, Jeffrey L Bennett, Richard J Nowak, Elias S Sotirchos, Erin E Longbrake, Emily M Mace, Kevin C O'Connor
A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases. Journal of immunology (Baltimore, Md. : 1950) 212 (5) (2024)
Sarah N Ohashi, Kevin C O'Connor
Plasmablasts from the past: Nostalgic B cells can't let go. Science immunology 8 (81) (2023)
Sarah N Ohashi, Kevin C O'Connor
Plasmablasts from the past: Nostalgic B cells can't let go. Science immunology 8 (81) (2023)
Sangwook Oh, Xuming Mao, Silvio M Vieira, Jinmin Lee, Darshil Patel, Eun Jung Choi, Andrea Alvarado, Ebony Cottman-Thomas, Damian Maseda, Patricia Y Tsao, Christoph T Ellebrecht, Sami L Khella, David P Richman, Kevin C O'Connor, Uri Herzberg, Gwendolyn K Binder, Michael C Milone, Samik Basu, Aimee S Payne
Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells. Nature biotechnology (2023)
Sangwook Oh, Xuming Mao, Silvio M Vieira, Jinmin Lee, Darshil Patel, Eun Jung Choi, Andrea Alvarado, Ebony Cottman-Thomas, Damian Maseda, Patricia Y Tsao, Christoph T Ellebrecht, Sami L Khella, David P Richman, Kevin C O'Connor, Uri Herzberg, Gwendolyn K Binder, Michael C Milone, Samik Basu, Aimee S Payne
Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells. Nature biotechnology (2023)
Gianvito Masi, Minh C Pham, Tabitha Karatz, Sangwook Oh, Aimee S Payne, Richard J Nowak, James F Howard, Jeffrey T Guptill, Vern C Juel, Kevin C O'Connor
Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis. Annals of clinical and translational neurology (2023)
Gianvito Masi, Minh C Pham, Tabitha Karatz, Sangwook Oh, Aimee S Payne, Richard J Nowak, James F Howard, Jeffrey T Guptill, Vern C Juel, Kevin C O'Connor
Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis. Annals of clinical and translational neurology (2023)
Ruoyi Jiang, Bhaskar Roy, Qian Wu, Subhasis Mohanty, Richard J Nowak, Albert C Shaw, Steven H Kleinstein, Kevin C O'Connor
The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties. ImmunoHorizons 7 (5) (2023)
Minh C Pham, Gianvito Masi, Rosa Patzina, Abeer H Obaid, Seneca R Oxendine, Sangwook Oh, Aimee S Payne, Richard J Nowak, Kevin C O'Connor
Individual myasthenia gravis autoantibody clones can efficiently mediate multiple mechanisms of pathology. Acta neuropathologica (2023)
Sangwook Oh, Xuming Mao, Silvio M Vieira, Jinmin Lee, Darshil Patel, Eun Jung Choi, Andrea Alvarado, Ebony Cottman-Thomas, Damian Maseda, Patricia Y Tsao, Christoph T Ellebrecht, Sami L Khella, David P Richman, Kevin C O'Connor, Uri Herzberg, Gwendolyn K Binder, Michael C Milone, Samik Basu, Aimee S Payne
Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells. Nature biotechnology (2023)
Alexandra C Bayer, Kevin C O'Connor
From drab to Fab; PLP1's fit is redressed for MS. Science immunology 8 (88) (2023)
Fatemeh Khani-Habibabadi, Kevin C O'Connor
Toddler's T cells are taught in muco-school. Science immunology 8 (86) (2023)
Sarah N Ohashi, Kevin C O'Connor
Plasmablasts from the past: Nostalgic B cells can't let go. Science immunology 8 (81) (2023)
Sangwook Oh, Xuming Mao, Silvio M Vieira, Jinmin Lee, Darshil Patel, Eun Jung Choi, Andrea Alvarado, Ebony Cottman-Thomas, Damian Maseda, Patricia Y Tsao, Christoph T Ellebrecht, Sami L Khella, David P Richman, Kevin C O'Connor, Uri Herzberg, Gwendolyn K Binder, Michael C Milone, Samik Basu, Aimee S Payne
Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells. Nature biotechnology (2023)
Sarah N Ohashi, Kevin C O'Connor
Plasmablasts from the past: Nostalgic B cells can't let go. Science immunology 8 (81) (2023)
Abeer H Obaid, Chryssa Zografou, Douangsone D Vadysirisack, Bailey Munro-Sheldon, Miriam L Fichtner, Bhaskar Roy, William M Philbrick, Jeffrey L Bennett, Richard J Nowak, Kevin C O'Connor
Heterogeneity of Acetylcholine Receptor Autoantibody-Mediated Complement Activity in Patients With Myasthenia Gravis. Neurology(R) neuroimmunology & neuroinflammation 9 (4) (2022)
Esen Sefik, Kevin C O'Connor
EBVerified TCRs and multiple sclerosis. Science immunology 7 (76) (2022)
Miriam L Fichtner, Kenneth B Hoehn, Easton E Ford, Marina Mane-Damas, Sangwook Oh, Patrick Waters, Aimee S Payne, Melissa L Smith, Corey T Watson, Mario Losen, Pilar Martinez-Martinez, Richard J Nowak, Steven H Kleinstein, Kevin C O'Connor
Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy. Acta neuropathologica communications 10 (1) (2022)
Caleigh Mandel-Brehm, Miriam L Fichtner, Ruoyi Jiang, Valerie J Winton, Sara E Vazquez, Minh C Pham, Kenneth B Hoehn, Michael P Snyder, Richard J Nowak, Steven H Kleinstein, Michael R Wilson, Joseph L DeRisi, Kevin C O'Connor
Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes. Journal of immunology (Baltimore, Md. : 1950) 207 (8) (2021)
Richard J Nowak, Christopher S Coffey, Jonathan M Goldstein, Mazen M Dimachkie, Michael Benatar, John T Kissel, Gil I Wolfe, Ted M Burns, Miriam L Freimer, Sharon Nations, Volkan Granit, A Gordon Smith, David P Richman, Emma Ciafaloni, Muhammad T Al-Lozi, Laura Ann Sams, Dianna Quan, Eroboghene Ubogu, Brenda Pearson, Aditi Sharma, Jon W Yankey, Liz Uribe, Michael Shy, Anthony A Amato, Robin Conwit, Kevin C O'Connor, David A Hafler, Merit E Cudkowicz, Richard J Barohn, null null
Phase 2 Trial of Rituximab in Acetylcholine Receptor Antibody-Positive Generalized Myasthenia Gravis: The BeatMG Study. Neurology (2021)
Panos Stathopoulos, Anne Chastre, Patrick Waters, Sarosh Irani, Miriam L Fichtner, Erik S Benotti, Joel M Guthridge, Jennifer Seifert, Richard J Nowak, Jane H Buckner, V Michael Holers, Judith A James, David A Hafler, Kevin C O'Connor
Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity. Journal of immunology (Baltimore, Md. : 1950) 202 (8) (2019)
Eric Meffre, Kevin C O'Connor
Impaired B-cell tolerance checkpoints promote the development of autoimmune diseases and pathogenic autoantibodies. Immunological reviews 292 (1) (2019)
Panos Stathopoulos, Aditya Kumar, Jason A Vander Heiden, Elba Pascual-Goñi, Richard J Nowak, Kevin C O'Connor
Mechanisms underlying B cell immune dysregulation and autoantibody production in MuSK myasthenia gravis. Annals of the New York Academy of Sciences 1412 (1) (2019)
Judith Fraussen, Susanna Marquez, Kazushiro Takata, Lien Beckers, Gwendoline Montes Diaz, Chrysoula Zografou, Bart Van Wijmeersch, Luisa M Villar, Kevin C O'Connor, Steven H Kleinstein, Veerle Somers
Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD-CD27- Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients. Journal of immunology (Baltimore, Md. : 1950) 203 (6) (2019)
Jason A Vander Heiden, Panos Stathopoulos, Julian Q Zhou, Luan Chen, Tamara J Gilbert, Christopher R Bolen, Richard J Barohn, Mazen M Dimachkie, Emma Ciafaloni, Teresa J Broering, Francois Vigneault, Richard J Nowak, Steven H Kleinstein, Kevin C O'Connor
Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing. Journal of immunology (Baltimore, Md. : 1950) 198 (4) (2017)
Ang Cui, Roberto Di Niro, Jason A Vander Heiden, Adrian W Briggs, Kris Adams, Tamara Gilbert, Kevin C O'Connor, Francois Vigneault, Mark J Shlomchik, Steven H Kleinstein
A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data. Journal of immunology (Baltimore, Md. : 1950) 197 (9) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kevin C O'Connor