Steven H Kleinstein (Steven Kleinstein)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 101

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Nature immunology

Nature communications

The Journal of experimental medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Stephen M Lanahan, Lucas Yang, Kate M Jones, Zhihong Qi, Emylette Cruz Cabrera, Lauren Y Cominsky, Anjali Ramaswamy, Anis Barmada, Gisela Gabernet, Dinesh Babu Uthaya Kumar, Lan Xu, Peiying Shan, Matthias P Wymann, Steven H Kleinstein, V Koneti Rao, Peter Mustillo, Neil Romberg, Roshini S Abraham, Carrie L Lucas
PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells. Nature immunology (2024)
Max Mattessich, Joaquin Reyna, Edel Aron, Ferhat Ay, Misha Kilmer, Steven H Kleinstein, Anna Konstorum
nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Non-linear Iterative Partial Least Squares. bioRxiv : the preprint server for biology (2024)
Rachel Sparks, Nicholas Rachmaninoff, William W Lau, Dylan C Hirsch, Neha Bansal, Andrew J Martins, Jinguo Chen, Candace C Liu, Foo Cheung, Laura E Failla, Angelique Biancotto, Giovanna Fantoni, Brian A Sellers, Daniel G Chawla, Katherine N Howe, Darius Mostaghimi, Rohit Farmer, Yuri Kotliarov, Katherine R Calvo, Cindy Palmer, Janine Daub, Ladan Foruraghi, Samantha Kreuzburg, Jennifer D Treat, Amanda K Urban, Anne Jones, Tina Romeo, Natalie T Deuitch, Natalia Sampaio Moura, Barbara Weinstein, Susan L Moir, Luigi Ferruci, Karyl S Barron, Ivona Aksentijevich, Steven H Kleinstein, Danielle M Townsley, Neal S Young, Anthony L Guerrerio, Gulbu Uzel, Gineth Paola Pinto-Patarroyo, Cornelia D Cudrici, Patrycja Hoffmann, Deborah L Stone, Amanda K Ombrello, Alexandra F Freeman, Christa S Zerbe, Daniel L Kastner, Steven M Holland, John S Tsang
A unified metric of human immune health. Nature medicine (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity. Nucleic acids research 52 (2) (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Derrick Callahan, Shuchi Smita, Stephen Joachim, Kenneth B Hoehn, Steven H Kleinstein, Florian J Weisel, Maria Chikina, Mark J Shlomchik
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature immunology (2024)
Jeremy P Gygi, Anna Konstorum, Shrikant Pawar, Edel Aron, Steven H Kleinstein, Leying Guan
A supervised Bayesian factor model for the identification of multi-omics signatures. Bioinformatics (Oxford, England) 40 (5) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Katherine M McIntire, Hailong Meng, Ting-Hui Lin, Wooseob Kim, Nina E Moore, Julianna Han, Meagan McMahon, Meng Wang, Sameer Kumar Malladi, Bassem M Mohammed, Julian Q Zhou, Aaron J Schmitz, Kenneth B Hoehn, Juan Manuel Carreño, Temima Yellin, Teresa Suessen, William Dana Middleton, Sharlene A Teefey, Rachel M Presti, Florian Krammer, Jackson S Turner, Andrew B Ward, Ian A Wilson, Steven H Kleinstein, Ali H Ellebedy
Maturation of germinal center B cells after influenza virus vaccination in humans. The Journal of experimental medicine 221 (8) (2024)
Camila H Coelho, Susanna Marquez, Bergeline C Nguemwo Tentokam, Anne D Berhe, Kazutoyo Miura, Vishal N Rao, Carole A Long, Ogobara K Doumbo, Issaka Sagara, Sara Anne Healy, Steven H Kleinstein, Patrick Emmet Duffy
Antibody gene features associated with binding and functional activity in malaria vaccine-derived human mAbs. NPJ vaccines 9 (1) (2024)
Katherine M McIntire, Hailong Meng, Ting-Hui Lin, Wooseob Kim, Nina E Moore, Julianna Han, Meagan McMahon, Meng Wang, Sameer Kumar Malladi, Bassem M Mohammed, Julian Q Zhou, Aaron J Schmitz, Kenneth B Hoehn, Juan Manuel Carreño, Temima Yellin, Teresa Suessen, William Dana Middleton, Sharlene A Teefey, Rachel M Presti, Florian Krammer, Jackson S Turner, Andrew B Ward, Ian A Wilson, Steven H Kleinstein, Ali H Ellebedy
Maturation of germinal center B cells after influenza virus vaccination in humans. The Journal of experimental medicine 221 (8) (2024)
Jeremy P Gygi, Anna Konstorum, Shrikant Pawar, Edel Aron, Steven H Kleinstein, Leying Guan
A supervised Bayesian factor model for the identification of multi-omics signatures. Bioinformatics (Oxford, England) 40 (5) (2024)
Jeremy P Gygi, Anna Konstorum, Shrikant Pawar, Edel Aron, Steven H Kleinstein, Leying Guan
A supervised Bayesian factor model for the identification of multi-omics signatures. Bioinformatics (Oxford, England) 40 (5) (2024)
Katherine M McIntire, Hailong Meng, Ting-Hui Lin, Wooseob Kim, Nina E Moore, Julianna Han, Meagan McMahon, Meng Wang, Sameer Kumar Malladi, Bassem M Mohammed, Julian Q Zhou, Aaron J Schmitz, Kenneth B Hoehn, Juan Manuel Carreño, Temima Yellin, Teresa Suessen, William Dana Middleton, Sharlene A Teefey, Rachel M Presti, Florian Krammer, Jackson S Turner, Andrew B Ward, Ian A Wilson, Steven H Kleinstein, Ali H Ellebedy
Maturation of germinal center B cells after influenza virus vaccination in humans. The Journal of experimental medicine 221 (8) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Cole G Jensen, Jacob A Sumner, Steven H Kleinstein, Kenneth B Hoehn
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of immunology (Baltimore, Md. : 1950) (2024)
Stephen M Lanahan, Lucas Yang, Kate M Jones, Zhihong Qi, Emylette Cruz Cabrera, Lauren Y Cominsky, Anjali Ramaswamy, Anis Barmada, Gisela Gabernet, Dinesh Babu Uthaya Kumar, Lan Xu, Peiying Shan, Matthias P Wymann, Steven H Kleinstein, V Koneti Rao, Peter Mustillo, Neil Romberg, Roshini S Abraham, Carrie L Lucas
PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells. Nature immunology 25 (8) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Cole G Jensen, Jacob A Sumner, Steven H Kleinstein, Kenneth B Hoehn
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of immunology (Baltimore, Md. : 1950) 212 (10) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Jeremy P Gygi, Anna Konstorum, Shrikant Pawar, Edel Aron, Steven H Kleinstein, Leying Guan
A supervised Bayesian factor model for the identification of multi-omics signatures. Bioinformatics (Oxford, England) 40 (5) (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Rachel Sparks, Nicholas Rachmaninoff, William W Lau, Dylan C Hirsch, Neha Bansal, Andrew J Martins, Jinguo Chen, Candace C Liu, Foo Cheung, Laura E Failla, Angelique Biancotto, Giovanna Fantoni, Brian A Sellers, Daniel G Chawla, Katherine N Howe, Darius Mostaghimi, Rohit Farmer, Yuri Kotliarov, Katherine R Calvo, Cindy Palmer, Janine Daub, Ladan Foruraghi, Samantha Kreuzburg, Jennifer D Treat, Amanda K Urban, Anne Jones, Tina Romeo, Natalie T Deuitch, Natalia Sampaio Moura, Barbara Weinstein, Susan L Moir, Luigi Ferruci, Karyl S Barron, Ivona Aksentijevich, Steven H Kleinstein, Danielle M Townsley, Neal S Young, Anthony L Guerrerio, Gulbu Uzel, Gineth Paola Pinto-Patarroyo, Cornelia D Cudrici, Patrycja Hoffmann, Deborah L Stone, Amanda K Ombrello, Alexandra F Freeman, Christa S Zerbe, Daniel L Kastner, Steven M Holland, John S Tsang
A unified metric of human immune health. Nature medicine (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction. bioRxiv : the preprint server for biology (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity. Nucleic acids research 52 (2) (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity. Nucleic acids research 52 (2) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Cole G Jensen, Jacob A Sumner, Steven H Kleinstein, Kenneth B Hoehn
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of immunology (Baltimore, Md. : 1950) (2024)
Max Mattessich, Joaquin Reyna, Edel Aron, Ferhat Ay, Misha Kilmer, Steven H Kleinstein, Anna Konstorum
nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Non-linear Iterative Partial Least Squares. bioRxiv : the preprint server for biology (2024)
Derrick Callahan, Shuchi Smita, Stephen Joachim, Kenneth B Hoehn, Steven H Kleinstein, Florian J Weisel, Maria Chikina, Mark J Shlomchik
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature immunology 25 (3) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Stephen M Lanahan, Lucas Yang, Kate M Jones, Zhihong Qi, Emylette Cruz Cabrera, Lauren Y Cominsky, Anjali Ramaswamy, Anis Barmada, Gisela Gabernet, Dinesh Babu Uthaya Kumar, Lan Xu, Peiying Shan, Matthias P Wymann, Steven H Kleinstein, V Koneti Rao, Peter Mustillo, Neil Romberg, Roshini S Abraham, Carrie L Lucas
PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells. Nature immunology 25 (8) (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity. Nucleic acids research 52 (2) (2024)
Cole G Jensen, Jacob A Sumner, Steven H Kleinstein, Kenneth B Hoehn
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of immunology (Baltimore, Md. : 1950) 212 (10) (2024)
Derrick Callahan, Shuchi Smita, Stephen Joachim, Kenneth B Hoehn, Steven H Kleinstein, Florian J Weisel, Maria Chikina, Mark J Shlomchik
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature immunology 25 (3) (2024)
Camila H Coelho, Susanna Marquez, Bergeline C Nguemwo Tentokam, Anne D Berhe, Kazutoyo Miura, Vishal N Rao, Carole A Long, Ogobara K Doumbo, Issaka Sagara, Sara Anne Healy, Steven H Kleinstein, Patrick Emmet Duffy
Antibody gene features associated with binding and functional activity in malaria vaccine-derived human mAbs. NPJ vaccines 9 (1) (2024)
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A McComsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick-Pierre Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari Christine Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, null null, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden Terry Maecker, Matthew C Altman, Ruth Rebecca Montgomery, Patrice M Becker, Nadine G Rouphael
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nature communications 15 (1) (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction. bioRxiv : the preprint server for biology (2024)
Cole G Jensen, Jacob A Sumner, Steven H Kleinstein, Kenneth B Hoehn
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of immunology (Baltimore, Md. : 1950) (2024)
Hoang Van Phan, Alexandra Tsitsiklis, Cole P Maguire, Elias K Haddad, Patrice M Becker, Seunghee Kim-Schulze, Brian Hyohyoung Lee, Jing Chen, Annmarie Hoch, Harry Pickering, Patrick van Zalm, Matthew C Altman, Alison D Augustine, Carolyn S Calfee, Steven E Bosinger, Charles B Cairns, Walter L Eckalbar, Leying Guan, Naresh Doni Jayavelu, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Bjoern Peters, Nadine G Rouphael, null null, Ruth Rebecca Montgomery, Elaine Reed, Joanna M Schaenman, Hanno Steen, Ofer Levy, Joann Diray-Arce, Charles R Langelier
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 16 (743) (2024)
Rachel Sparks, Nicholas Rachmaninoff, William W Lau, Dylan C Hirsch, Neha Bansal, Andrew J Martins, Jinguo Chen, Candace C Liu, Foo Cheung, Laura E Failla, Angelique Biancotto, Giovanna Fantoni, Brian A Sellers, Daniel G Chawla, Katherine N Howe, Darius Mostaghimi, Rohit Farmer, Yuri Kotliarov, Katherine R Calvo, Cindy Palmer, Janine Daub, Ladan Foruraghi, Samantha Kreuzburg, Jennifer D Treat, Amanda K Urban, Anne Jones, Tina Romeo, Natalie T Deuitch, Natalia Sampaio Moura, Barbara Weinstein, Susan L Moir, Luigi Ferruci, Karyl S Barron, Ivona Aksentijevich, Steven H Kleinstein, Danielle M Townsley, Neal S Young, Anthony L Guerrerio, Gulbu Uzel, Gineth Paola Pinto-Patarroyo, Cornelia D Cudrici, Patrycja Hoffmann, Deborah L Stone, Amanda K Ombrello, Alexandra F Freeman, Christa S Zerbe, Daniel L Kastner, Steven M Holland, John S Tsang
A unified metric of human immune health. Nature medicine (2024)
Derrick Callahan, Shuchi Smita, Stephen Joachim, Kenneth B Hoehn, Steven H Kleinstein, Florian J Weisel, Maria Chikina, Mark J Shlomchik
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature immunology 25 (3) (2024)
Derrick Callahan, Shuchi Smita, Stephen Joachim, Kenneth B Hoehn, Steven H Kleinstein, Florian J Weisel, Maria Chikina, Mark J Shlomchik
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature immunology 25 (3) (2024)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction. bioRxiv : the preprint server for biology (2024)
Cole G Jensen, Jacob A Sumner, Steven H Kleinstein, Kenneth B Hoehn
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of immunology (Baltimore, Md. : 1950) 212 (10) (2024)
Kevin M Nickerson, Shuchi Smita, Kenneth B Hoehn, Anthony D Marinov, Kayla B Thomas, Justin T Kos, Yi Yang, Sheldon I Bastacky, Corey T Watson, Steven H Kleinstein, Mark J Shlomchik
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of experimental medicine 220 (5) (2023)
Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity. Nucleic acids research (2023)
Jeremy P Gygi, Anna Konstorum, Shrikant Pawar, Steven H Kleinstein, Leying Guan
SPEAR: a Sparse Supervised Bayesian Factor Model for Multi-omic Integration. bioRxiv : the preprint server for biology (2023)
Kevin M Nickerson, Shuchi Smita, Kenneth B Hoehn, Anthony D Marinov, Kayla B Thomas, Justin T Kos, Yi Yang, Sheldon I Bastacky, Corey T Watson, Steven H Kleinstein, Mark J Shlomchik
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of experimental medicine 220 (5) (2023)
Kevin M Nickerson, Shuchi Smita, Kenneth B Hoehn, Anthony D Marinov, Kayla B Thomas, Justin T Kos, Yi Yang, Sheldon I Bastacky, Corey T Watson, Steven H Kleinstein, Mark J Shlomchik
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of experimental medicine 220 (5) (2023)
Ruoyi Jiang, Bhaskar Roy, Qian Wu, Subhasis Mohanty, Richard J Nowak, Albert C Shaw, Steven H Kleinstein, Kevin C O'Connor
The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties. ImmunoHorizons 7 (5) (2023)
Miyo Ota, Kenneth B Hoehn, Takayuki Ota, Carlos José Aranda, Sara Friedman, Weslley F Braga, Alefiyah Malbari, Steven H Kleinstein, Scott Howard Sicherer, Maria A Curotto de Lafaille
The memory of pathogenic IgE is contained within CD23 + IgG1 + memory B cells poised to switch to IgE in food allergy. bioRxiv : the preprint server for biology (2023)
Charles R Langelier, Harry Pickering, Joanna Schaenman, Hoang Phan, Cole P Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Higuita, Mark Atkinson, Scott Breckenridge, Monica Fung, William Messer, null null, Ramin Salehi-Rad, Matthew C Altman, Patrice M Becker, Steven E Bosinger, Walter Eckalbar, Annmarie Hoch, Naresh Jayavelu, Seunghee Kim-Schulze, Meagan M Jenkins, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Joann Diray-Arce, Albert Shaw, Lindsey Baden, Ofer Levy, Elaine Reed
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Research square (2023)
Jeremy P Gygi, Cole P Maguire, Ravi K Patel, Pramod Shinde, Anna Konstorum, Casey P Shannon, Leqi Xu, Annmarie Hoch, Naresh Doni Jayavelu, Impacc Network, Elias K Haddad, Elaine F Reed, Monica Kraft, Grace A McComsey, Jordan P Metcalf, Al Ozonoff, Denise A Esserman, Charles B Cairns, Nadine G Rouphael, Steven E Bosinger, Seunghee Kim-Schulze, Florian Krammer, Lindsey B Rosen, Harm van Bakel, Michael R Wilson, Walter L Eckalbar, Holden Terry Maecker, Charles R Langelier, Hanno Steen, Matthew C Altman, Ruth Rebecca Montgomery, Ofer Levy, Esther Melamed, Bali Pulendran, Joann Diray-Arce, Kinga K Smolen, Gabriela K Fragiadakis, Patrice M Becker, Alison D Augustine, Rafick-Pierre Sekaly, Lauren I R Ehrlich, Slim Fourati, Bjoern Peters, Steven H Kleinstein, Leying Guan
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants. bioRxiv : the preprint server for biology (2023)
Kevin M Nickerson, Shuchi Smita, Kenneth B Hoehn, Anthony D Marinov, Kayla B Thomas, Justin T Kos, Yi Yang, Sheldon I Bastacky, Corey T Watson, Steven H Kleinstein, Mark J Shlomchik
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of experimental medicine 220 (5) (2023)
Charles R Langelier, Harry Pickering, Joanna Schaenman, Hoang Phan, Cole P Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Higuita, Mark Atkinson, Scott Breckenridge, Monica Fung, William Messer, null null, Ramin Salehi-Rad, Matthew C Altman, Patrice M Becker, Steven E Bosinger, Walter Eckalbar, Annmarie Hoch, Naresh Jayavelu, Seunghee Kim-Schulze, Meagan M Jenkins, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Joann Diray-Arce, Albert Shaw, Lindsey Baden, Ofer Levy, Elaine Reed
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Research square (2023)
Xi Chen, Yuan Wang, Antonio Cappuccio, Wan-Sze Cheng, Frederique Ruf Zamojski, Venugopalan D Nair, Clare M Miller, Aliza B Rubenstein, German Nudelman, Alicja Tadych, Chandra L Theesfeld, Alexandria Vornholt, Mary-Catherine George, Felicia Ruffin, Michael Dagher, Daniel G Chawla, Alessandra Soares-Schanoski, Rachel R Spurbeck, Lishomwa C Ndhlovu, Robert Sebra, Steven H Kleinstein, Andrew G Letizia, Irene Ramos, Vance G Fowler, Christopher W Woods, Elena Zaslavsky, Olga G Troyanskaya, Stuart C Sealfon
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data. Nature computational science 3 (7) (2023)
Pramod Shinde, Ferran Soldevila, Joaquin Reyna, Minori Aoki, Mikkel Rasmussen, Lisa Willemsen, Mari Kojima, Brendan Ha, Jason A Greenbaum, James A Overton, Hector Guzman-Orozco, Somayeh Nili, Shelby Orfield, Jeremy P Gygi, Ricardo da Silva Antunes, Alessandro Sette, Barry J Grant, Lars Rønn Olsen, Anna Konstorum, Leying Guan, Ferhat Ay, Steven H Kleinstein, Bjoern Peters
A systems vaccinology resource to develop and test computational models of immunity. bioRxiv : the preprint server for biology (2023)
Kevin M Nickerson, Shuchi Smita, Kenneth B Hoehn, Anthony D Marinov, Kayla B Thomas, Justin T Kos, Yi Yang, Sheldon I Bastacky, Corey T Watson, Steven H Kleinstein, Mark J Shlomchik
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of experimental medicine 220 (5) (2023)
Charles R Langelier, Harry Pickering, Joanna Schaenman, Hoang Phan, Cole P Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Higuita, Mark Atkinson, Scott Breckenridge, Monica Fung, William Messer, null null, Ramin Salehi-Rad, Matthew C Altman, Patrice M Becker, Steven E Bosinger, Walter Eckalbar, Annmarie Hoch, Naresh Jayavelu, Seunghee Kim-Schulze, Meagan M Jenkins, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Joann Diray-Arce, Albert Shaw, Lindsey Baden, Ofer Levy, Elaine Reed
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Research square (2023)
Kevin M Nickerson, Shuchi Smita, Kenneth B Hoehn, Anthony D Marinov, Kayla B Thomas, Justin T Kos, Yi Yang, Sheldon I Bastacky, Corey T Watson, Steven H Kleinstein, Mark J Shlomchik
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of experimental medicine 220 (5) (2023)
Ayelet Peres, William D Lees, Oscar L Rodriguez, Noah Y Lee, Pazit Polak, Ronen Hope, Meirav Kedmi, Andrew M Collins, Mats Ohlin, Steven H Kleinstein, Corey T Watson, Gur Yaari
IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data. Nucleic acids research (2023)
Charles R Langelier, Harry Pickering, Joanna Schaenman, Hoang Phan, Cole P Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Higuita, Mark Atkinson, Scott Breckenridge, Monica Fung, William Messer, Impacc Network, Ramin Salehi-Rad, Matthew C Altman, Patrice M Becker, Steven E Bosinger, Walter Eckalbar, Annmarie Hoch, Naresh Jayavelu, Seunghee Kim-Schulze, Meagan M Jenkins, Steven H Kleinstein, Florian Krammer, Holden Terry Maecker, Al Ozonoff, Joann Diray-Arce, Albert Shaw, Lindsey Baden, Ofer Levy, Elaine Reed
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Research square (2023)
Thomas Hagan, Bram Gerritsen, Lewis E Tomalin, Slim Fourati, Matthew P Mulè, Daniel G Chawla, Dmitri Rychkov, Evan Henrich, Helen E R Miller, Joann Diray-Arce, Patrick Dunn, Audrey Lee, null null, Ofer Levy, Raphaël Gottardo, Minne M Sarwal, John S Tsang, Mayte Suárez-Fariñas, Rafick-Pierre Sékaly, Steven H Kleinstein, Bali Pulendran
Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Nature immunology (2022)
Qin Xu, Pedro Milanez-Almeida, Andrew J Martins, Andrea J Radtke, Kenneth B Hoehn, Cihan Oguz, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney R Stein, Sabrina Ramelli, Juraj Kabat, Hengameh K Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick C Duncker, Moses M Kitakule, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace A Smith, Arthur Shaffer, Ian T McBain, Peter J McGuire, Stefania Pittaluga, Ronald N Germain, Richard Apps, Daniella M Schwartz, Kaitlyn Sadtler, Susan Moir, Daniel S Chertow, Steven H Kleinstein, Surender Khurana, John S Tsang, Pamela Mudd, Pamela L Schwartzberg, Kalpana Manthiram
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children. Nature immunology 24 (1) (2022)
Qin Xu, Pedro Milanez-Almeida, Andrew J Martins, Andrea J Radtke, Kenneth B Hoehn, Cihan Oguz, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney R Stein, Sabrina Ramelli, Juraj Kabat, Hengameh K Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick C Duncker, Moses M Kitakule, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace A Smith, Arthur Shaffer, Ian T McBain, Peter J McGuire, Stefania Pittaluga, Ronald N Germain, Richard Apps, Daniella M Schwartz, Kaitlyn Sadtler, Susan Moir, Daniel S Chertow, Steven H Kleinstein, Surender Khurana, John S Tsang, Pamela Mudd, Pamela L Schwartzberg, Kalpana Manthiram
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children. Nature immunology (2022)
Qin Xu, Pedro Milanez-Almeida, Andrew J Martins, Andrea J Radtke, Kenneth B Hoehn, Cihan Oguz, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney R Stein, Sabrina Ramelli, Juraj Kabat, Hengameh K Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick C Duncker, Moses M Kitakule, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace A Smith, Arthur Shaffer, Ian T McBain, Peter J McGuire, Stefania Pittaluga, Ronald N Germain, Richard Apps, Daniella M Schwartz, Kaitlyn Sadtler, Susan Moir, Daniel S Chertow, Steven H Kleinstein, Surender Khurana, John S Tsang, Pamela Mudd, Pamela L Schwartzberg, Kalpana Manthiram
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children. Nature immunology 24 (1) (2022)
Kenneth C Smith, Daniel G Chawla, Bhavjinder Kaur Dhillon, Zhou Ji, Randi Vita, Eva C van der Leest, Jing Yi Jessica Weng, Ernest Tang, Amani Abid, null null, Bjoern Peters, Robert E W Hancock, Aris Floratos, Steven H Kleinstein
A curated collection of human vaccination response signatures. Scientific data 9 (1) (2022)
Slim Fourati, Lewis E Tomalin, Matthew P Mulè, Daniel G Chawla, Bram Gerritsen, Dmitry Rychkov, Evan Henrich, Helen E R Miller, Thomas Hagan, Joann Diray-Arce, Patrick Dunn, null null, Ofer Levy, Raphael Gottardo, Minnie M Sarwal, John S Tsang, Mayte Suárez-Fariñas, Bali Pulendran, Steven H Kleinstein, Rafick-Pierre Sekaly
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination. Nature immunology (2022)
Joann Diray-Arce, Helen E R Miller, Evan Henrich, Bram Gerritsen, Matthew P Mulè, Slim Fourati, Jeremy Gygi, Thomas Hagan, Lewis E Tomalin, Dmitry Rychkov, Dmitri Kazmin, Daniel G Chawla, Hailong Meng, Patrick Dunn, John Campbell, null null, Minnie Sarwal, John S Tsang, Ofer Levy, Bali Pulendran, Rafick Sekaly, Aris Floratos, Raphaël Gottardo, Steven H Kleinstein, Mayte Suárez-Fariñas
The Immune Signatures data resource, a compendium of systems vaccinology datasets. Scientific data 9 (1) (2022)
Avraham Unterman, Tomokazu S Sumida, Nima Nouri, Xiting Yan, Amy Y Zhao, Victor Gasque, Jonas Christian Schupp, Hiromitsu Asashima, Yunqing Liu, Carlos Cosme, Wenxuan Deng, Ming Chen, Micha Sam Brickman Raredon, Kenneth B Hoehn, Guilin Wang, Zuoheng Wang, Giuseppe DeIuliis, Neal G Ravindra, Ningshan Li, Christopher Castaldi, Patrick Wong, John Fournier, Santos Bermejo, Lokesh Sharma, Arnau Casanovas-Massana, Chantal B F Vogels, Chantal B F Vogels, Nathan D Grubaugh, Anthony Melillo, Hailong Meng, Yan Stein, Maksym Minasyan, Subhasis Mohanty, William E Ruff, Inessa Cohen, Khadir Raddassi, null null, Laura E Niklason, Albert I Ko, Ruth Rebecca Montgomery, Shelli F Farhadian, Akiko Iwasak, Albert C Shaw, David van Dijk, Hongyu Zhao, Steven H Kleinstein, David A Hafler, Naftali Kaminski, Charles Dela Cruz
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19. Nature communications 13 (1) (2022)
Kenneth B Hoehn, Oliver George Pybus, Steven H Kleinstein
Phylogenetic analysis of migration, differentiation, and class switching in B cells. PLoS computational biology 18 (4) (2022)
Kalpana Manthiram, Qin Xu, Pedro Milanez-Almeida, Andrew J Martins, Andrea J Radtke, Kenneth B Hoehn, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney R Stein, Sabrina Ramelli, Juraj Kabat, Hengameh Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick Duncker, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace A Smith, Arthur Shaffer, Ian McBain, Stefania Pittaluga, Ronald N Germain, Richard Apps, Kaitlyn Sadtler, Susan Moir, Daniel S Chertow, Steven H Kleinstein, Surender Khurana, John S Tsang, Pamela Mudd, Pamela L Schwartzberg
Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children. Research square (2022)
Qin Xu, Pedro Milanez-Almeida, Andrew J Martins, Andrea J Radtke, Kenneth B Hoehn, Cihan Oguz, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney R Stein, Sabrina Ramelli, Juraj Kabat, Hengameh K Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick C Duncker, Moses M Kitakule, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace A Smith, Arthur Shaffer, Ian T McBain, Peter J McGuire, Stefania Pittaluga, Ronald N Germain, Richard Apps, Daniella M Schwartz, Kaitlyn Sadtler, Susan Moir, Daniel S Chertow, Steven H Kleinstein, Surender Khurana, John S Tsang, Pamela Mudd, Pamela L Schwartzberg, Kalpana Manthiram
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children. Nature immunology 24 (1) (2022)
Caleigh Mandel-Brehm, Miriam L Fichtner, Ruoyi Jiang, Valerie J Winton, Sara E Vazquez, Minh C Pham, Kenneth B Hoehn, Michael P Snyder, Richard J Nowak, Steven H Kleinstein, Michael R Wilson, Joseph L DeRisi, Kevin C O'Connor
Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes. Journal of immunology (Baltimore, Md. : 1950) 207 (8) (2021)
Kenneth B Hoehn, Jackson S Turner, Frederick I Miller, Ruoyi Jiang, Oliver G Pybus, Ali H Ellebedy, Steven H Kleinstein
Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving. eLife 10 (2021)
Kenneth B Hoehn, Palaniappan Ramanathan, Avraham Unterman, Tomokazu S Sumida, Hiromitsu Asashima, David A Hafler, Naftali Kaminski, Charles Dela Cruz, Stuart C Sealfon, Alexander Bukreyev, Steven H Kleinstein
Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19. Journal of immunology (Baltimore, Md. : 1950) (2021)
Simone Brioschi, Wei-Le Wang, Vincent Peng, Meng Wang, Irina Shchukina, Zev J Greenberg, Jennifer K Bando, Natalia Jaeger, Rafael S Czepielewski, Amanda Swain, Denis A Mogilenko, Wandy L Beatty, Peter Bayguinov, James A J Fitzpatrick, Laura G Schuettpelz, Catrina C Fronick, Igor Smirnov, Jonathan Kipnis, Virginia Smith Shapiro, Gregory F Wu, Susan Gilfillan, Marina Cella, Maxim N Artyomov, Steven H Kleinstein, Marco Colonna
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders. Science (New York, N.Y.) 373 (6553) (2021)
Ji Eun Oh, Eric Song, Miyu Moriyama, Patrick Wong, Sophia Zhang, Ruoyi Jiang, Shirin Strohmeier, Steven H Kleinstein, Florian Krammer, Akiko Iwasak
Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA. Science immunology 6 (66) (2021)
Ruoyi Jiang, Kenneth B Hoehn, Casey S Lee, Minh C Pham, Robert J Homer, Frank C Detterbeck, Inmaculada Aban, Leslie Jacobson, Angela Vincent, Richard J Nowak, Henry J Kaminski, Steven H Kleinstein, Kevin C O'Connor
Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Ang Cui, Daniel G Chawla, Steven H Kleinstein
Sex-Biased Aging Effects on Ig Somatic Hypermutation Targeting. Journal of immunology (Baltimore, Md. : 1950) 206 (1) (2020)
Nima Nouri, Steven H Kleinstein
Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data. PLoS computational biology 16 (6) (2020)
Jackson S Turner, Julian Q Zhou, Julianna Han, Aaron J Schmitz, Amena A Rizk, Wafaa B Alsoussi, Tingting Lei, Mostafa Amor, Katherine M McIntire, Philip Meade, Shirin Strohmeier, Rafael I Brent, Sara T Richey, Alem Haile, Yuhe R Yang, Michael K Klebert, Teresa Suessen, Sharlene Teefey, Rachel M Presti, Florian Krammer, Steven H Kleinstein, Andrew B Ward, Ali H Ellebedy
Human germinal centres engage memory and naive B cells after influenza vaccination. Nature 586 (7827) (2020)
Julian Q Zhou, Steven H Kleinstein
Position-Dependent Differential Targeting of Somatic Hypermutation. Journal of immunology (Baltimore, Md. : 1950) 205 (12) (2020)
Stefan Avey, Subhasis Mohanty, Daniel G Chawla, Hailong Meng, Thilinie D Bandaranayake, Ikuyo Ueda, Heidi J Zapata, Koonam Park, Tamara P Blevins, Sui Tsang, Robert B Belshe, Susan M Kaech, Albert C Shaw, Steven H Kleinstein
Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults. Journal of immunology (Baltimore, Md. : 1950) 204 (6) (2020)
Wafaa B Alsoussi, Jackson S Turner, James Brett Case, Haiyan Zhao, Aaron J Schmitz, Julian Q Zhou, Rita E Chen, Tingting Lei, Amena A Rizk, Katherine M McIntire, Emma S Winkler, Julie M Fox, Natasha M Kafai, Larissa B Thackray, Ahmed O Hassan, Fatima Amanat, Florian Krammer, Corey T Watson, Steven H Kleinstein, Daved H Fremont, Michael S Diamond, Ali H Ellebedy
A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. Journal of immunology (Baltimore, Md. : 1950) 205 (4) (2020)
James W Austin, Clarisa M Buckner, Lela Kardava, Wei Wang, Xiaozhen Zhang, Valerie A Melson, Ryan G Swanson, Andrew J Martins, Julian Q Zhou, Kenneth B Hoehn, J Nicholas Fisk, Yiannis Dimopoulos, Alexander Chassiakos, Sijy O'Dell, Margery G Smelkinson, Catherine A Seamon, Richard W Kwan, Michael C Sneller, Stefania Pittaluga, Nicole A Doria-Rose, Adrian B McDermott, Yuxing Li, Tae-Wook Chun, Steven H Kleinstein, John S Tsang, Constantinos Petrovas, Susan L Moir
Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation. Science translational medicine 11 (520) (2020)
Hailong Meng, Gur Yaari, Christopher R Bolen, Stefan Avey, Steven H Kleinstein
Gene set meta-analysis with Quantitative Set Analysis for Gene Expression (QuSAGE). PLoS computational biology 15 (4) (2019)
Julian Q Zhou, Steven H Kleinstein
Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal Relationships. Journal of immunology (Baltimore, Md. : 1950) 203 (7) (2019)
Judith Fraussen, Susanna Marquez, Kazushiro Takata, Lien Beckers, Gwendoline Montes Diaz, Chrysoula Zografou, Bart Van Wijmeersch, Luisa M Villar, Kevin C O'Connor, Steven H Kleinstein, Veerle Somers
Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD-CD27- Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients. Journal of immunology (Baltimore, Md. : 1950) 203 (6) (2019)
Yuan Zhao, Mohamed Uduman, Jacqueline H Y Siu, Thomas J Tull, Jeremy D Sanderson, Yu-Chang Bryan Wu, Julian Q Zhou, Nedyalko Petrov, Richard Ellis, Katrina Todd, Konstantia-Maria Chavele, William Guesdon, Anna Vossenkamper, Wayel Jassem, David P D'Cruz, David J Fear, Susan John, Dagmar Scheel-Toellner, Claire Hopkins, Estefania Moreno, Natalie L Woodman, Francesca Ciccarelli, Susanne Heck, Steven H Kleinstein, Mats Bemark, Jo Spencer
Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue. Nature communications 9 (1) (2018)
Corey T Watson, Frederick A Matsen, Katherine J L Jackson, Ali Bashir, Melissa Laird Smith, Jacob Glanville, Felix Breden, Steven H Kleinstein, Andrew M Collins, Christian E Busse
Comment on "A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data". Journal of immunology (Baltimore, Md. : 1950) 198 (9) (2018)
Brian J Laidlaw, Yisi Lu, Robert A Amezquita, Jason S Weinstein, Jason A Vander Heiden, Namita T Gupta, Steven H Kleinstein, Susan M Kaech, Joseph E Craft
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response. Science immunology 2 (16) (2018)

Steven H Kleinstein.css-eqlu8i{font-size:small;padding-left:4px;} (Steven Kleinstein)

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Steven H Kleinstein (Steven Kleinstein)