Lance C Seefeldt (Lance Seefeldt, L C Seefeldt)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 50

Top Venues

Journal of the American Chemical Society

Biochemistry

eLife

mBio

Utah State University

University of California Riverside (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Utah State University Apr 01 2002

United States

Professor :: Chemistry and Biochemistry

Utah State University Apr 01 1998 - Apr 01 2002

United States

Associate Professor :: Chemistry and Biochemistry

Utah State University Aug 01 1993 - Apr 01 1998

United States

Assistant Professor :: Chemistry and Biochemistry

University of Georgia Apr 01 1989 - Aug 01 1993

United States

Postdoctoral Fellow :: Biochemistry

University of California Riverside Aug 01 1983 - Apr 01 1989

United States

Research Assistant :: Biochemistry

Education History

University of California Riverside Aug 01 1983 - Apr 01 1989

United States

PHD :: Biochemistry

University of Redlands Aug 01 1979 - May 01 1983

United States

BSC :: Chemistry

Publications

Derek F Harris, Holly R Rucker, Amanda K Garcia, Zhi-Yong Yang, Scott D Chang, Hannah Feinsilber, Betül Kaçar, Lance C Seefeldt
Ancient nitrogenases are ATP dependent. mBio 15 (7) (2024)
Derek F Harris, Holly R Rucker, Amanda K Garcia, Zhi-Yong Yang, Scott D Chang, Hannah Feinsilber, Betül Kaçar, Lance C Seefeldt
Ancient nitrogenases are ATP dependent. mBio (2024)
Derek F Harris, Holly R Rucker, Amanda K Garcia, Zhi-Yong Yang, Scott D Chang, Hannah Feinsilber, Betül Kaçar, Lance C Seefeldt
Ancient nitrogenases are ATP dependent. mBio 15 (7) (2024)
Derek F Harris, Holly R Rucker, Amanda K Garcia, Zhi-Yong Yang, Scott D Chang, Hannah Feinsilber, Betül Kaçar, Lance C Seefeldt
Ancient nitrogenases are ATP dependent. mBio 15 (7) (2024)
Zhi-Yong Yang, Artavazd Badalyan, Brian M Hoffman, Dennis R Dean, Lance C Seefeldt
The Fe Protein Cycle Associated with Nitrogenase Catalysis Requires the Hydrolysis of Two ATP for Each Single Electron Transfer Event. Journal of the American Chemical Society (2023)
Lauren M Pellows, Gregory E Vansuch, Bryant Chica, Zhi-Yong Yang, Jesse L Ruzicka, Mark A Willis, Andrew Clinger, Katherine A Brown, Lance C Seefeldt, John W Peters, Gordana Dukovic, David W Mulder, Paul W King
Low-temperature trapping of N2 reduction reaction intermediates in nitrogenase MoFe protein-CdS quantum dot complexes. The Journal of chemical physics 159 (23) (2023)
Amanda K Garcia, Derek F Harris, Alex J Rivier, Brooke M Carruthers, Azul Pinochet-Barros, Lance C Seefeldt, Betül Kaçar
Nitrogenase resurrection and the evolution of a singular enzymatic mechanism. eLife 12 (2023)
Amanda K Garcia, Derek F Harris, Alex J Rivier, Brooke M Carruthers, Azul Pinochet-Barros, Lance C Seefeldt, Betül Kaçar
Nitrogenase resurrection and the evolution of a singular enzymatic mechanism. eLife 12 (2023)
Zhi-Yong Yang, Artavazd Badalyan, Brian M Hoffman, Dennis R Dean, Lance C Seefeldt
The Fe Protein Cycle Associated with Nitrogenase Catalysis Requires the Hydrolysis of Two ATP for Each Single Electron Transfer Event. Journal of the American Chemical Society 145 (10) (2023)
Amanda K Garcia, Derek F Harris, Alex J Rivier, Brooke M Carruthers, Azul Pinochet-Barros, Lance C Seefeldt, Betül Kaçar
Nitrogenase resurrection and the evolution of a singular enzymatic mechanism. eLife 12 (2023)
Lauren M Pellows, Mark A Willis, Jesse L Ruzicka, Bhanu P Jagilinki, David W Mulder, Zhi-Yong Yang, Lance C Seefeldt, Paul W King, Gordana Dukovic, John W Peters
High Affinity Electrostatic Interactions Support the Formation of CdS Quantum Dot:Nitrogenase MoFe Protein Complexes. Nano letters (2023)
Amanda K Garcia, Derek F Harris, Alex J Rivier, Brooke M Carruthers, Azul Pinochet-Barros, Lance C Seefeldt, Betül Kaçar
Nitrogenase resurrection and the evolution of a singular enzymatic mechanism. eLife 12 (2023)
Ting Chen, Philip A Ash, Lance C Seefeldt, Kylie A Vincent
Electrochemical experiments define potentials associated with binding of substrates and inhibitors to nitrogenase MoFe protein. Faraday discussions (2023)
Zhi-Yong Yang, Artavazd Badalyan, Brian M Hoffman, Dennis R Dean, Lance C Seefeldt
The Fe Protein Cycle Associated with Nitrogenase Catalysis Requires the Hydrolysis of Two ATP for Each Single Electron Transfer Event. Journal of the American Chemical Society 145 (10) (2023)
Gregory E Vansuch, David W Mulder, Bryant Chica, Jesse L Ruzicka, Zhi-Yong Yang, Lauren M Pellows, Mark A Willis, Katherine A Brown, Lance C Seefeldt, John W Peters, Gordana Dukovic, Paul W King
Cryo-annealing of Photoreduced CdS Quantum Dot-Nitrogenase MoFe Protein Complexes Reveals the Kinetic Stability of the E 4 (2N2H) Intermediate. Journal of the American Chemical Society (2023)
Dmitriy A Lukoyanov, Zhi-Yong Yang, Krista Shisler, John W Peters, Simone Raugei, Dennis R Dean, Lance C Seefeldt, Brian M Hoffman
A conformational equilibrium in the nitrogenase MoFe protein with an α-V70I amino acid substitution illuminates the mechanism of H 2 formation. Faraday discussions (2023)
Fatima Abi Ghaida, Katharina Brinkert, Ping Chen, Serena DeBeer, Brian M Hoffman, Patrick L Holland, Shoba Laxmi, Douglas Robert MacFarlane, Jonas C Peters, John W Peters, Christopher J Pickett, Lance C Seefeldt, Sergii I Shylin, Ifan E L Stephens, Kylie A Vincent, Qianru Wang, Olivia Westhead
Enzymatic N 2 activation: general discussion. Faraday discussions (2023)
Amanda K Garcia, Derek F Harris, Alex J Rivier, Brooke M Carruthers, Azul Pinochet-Barros, Lance C Seefeldt, Betül Kaçar
Nitrogenase resurrection and the evolution of a singular enzymatic mechanism. eLife 12 (2023)
Dmitriy A Lukoyanov, Derek F Harris, Zhi-Yong Yang, Ana Pérez-González, Dennis R Dean, Lance C Seefeldt, Brian M Hoffman
The One-Electron Reduced Active-Site FeFe-Cofactor of Fe-Nitrogenase Contains a Hydride Bound to a Formally Oxidized Metal-Ion Core. Inorganic chemistry 61 (14) (2022)
Derek F Harris, Artavazd Badalyan, Lance C Seefeldt
Mechanistic Insights into Nitrogenase FeMo-Cofactor Catalysis through a Steady-State Kinetic Model. Biochemistry 61 (19) (2022)
Casey Van Stappen, Emilio Jiménez-Vicente, Ana Pérez-González, Zhi-Yong Yang, Lance C Seefeldt, Serena DeBeer, Dennis R Dean, Laure Decamps
A conformational role for NifW in the maturation of molybdenum nitrogenase P-cluster. Chemical science 13 (12) (2022)
Dmitriy A Lukoyanov, Zhi-Yong Yang, Ana Pérez-González, Simone Raugei, Dennis R Dean, Lance C Seefeldt, Brian M Hoffman
13 C ENDOR Characterization of the Central Carbon within the Nitrogenase Catalytic Cofactor Indicates That the CFe 6 Core Is a Stabilizing "Heart of Steel". Journal of the American Chemical Society 144 (40) (2022)
Bryant Chica, Jesse Ruzicka, Lauren M Pellows, Hayden Kallas, Effie Kisgeropoulos, Gregory E Vansuch, David W Mulder, Katherine A Brown, Drazenka Svedruzic, John W Peters, Gordana Dukovic, Lance C Seefeldt, Paul W King
Dissecting Electronic-Structural Transitions in the Nitrogenase MoFe Protein P-Cluster during Reduction. Journal of the American Chemical Society 144 (13) (2022)
Ana Pérez-González, Emilio Jimenez-Vicente, Alvaro Salinero-Lanzarote, Derek F Harris, Lance C Seefeldt, Dennis R Dean
AnfO controls fidelity of nitrogenase FeFe protein maturation by preventing misincorporation of FeV-cofactor. Molecular microbiology 117 (5) (2022)
Qi Huang, Monika Tokmina-Lukaszewska, Lewis E Johnson, Hayden Kallas, Bojana Ginovska, John W Peters, Lance C Seefeldt, Brian Bothner, Simone Raugei
Mechanical coupling in the nitrogenase complex. PLoS computational biology 17 (3) (2021)
Ana Pérez-González, Zhi-Yong Yang, Dmitriy A Lukoyanov, Dennis R Dean, Lance C Seefeldt, Brian M Hoffman
Exploring the Role of the Central Carbide of the Nitrogenase Active-Site FeMo-cofactor through Targeted 13C Labeling and ENDOR Spectroscopy. Journal of the American Chemical Society 143 (24) (2021)
Zhi-Yong Yang, Emilio Jimenez-Vicente, Hayden Kallas, Dmitriy A Lukoyanov, Hao Yang, Julia S Martin Del Campo, Dennis R Dean, Brian M Hoffman, Lance C Seefeldt
The electronic structure of FeV-cofactor in vanadium-dependent nitrogenase. Chemical science 12 (20) (2021)
John W Peters, Oliver Einsle, Dennis R Dean, Serena DeBeer, Brian M Hoffman, Patrick L Holland, Lance C Seefeldt
Comment on "Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase". Science (New York, N.Y.) 371 (6530) (2021)
Lance C Seefeldt, Zhi-Yong Yang, Dmitriy A Lukoyanov, Derek F Harris, Dennis R Dean, Simone Raugei, Brian M Hoffman
Reduction of Substrates by Nitrogenases. Chemical reviews 120 (12) (2020)
David P Hickey, Rong Cai, Zhi-Yong Yang, Katharina Grunau, Oliver Einsle, Lance C Seefeldt, Shelley D Minteer
Correction to "Establishing a Thermodynamic Landscape for the Active Site of Mo-Dependent Nitrogenase". Journal of the American Chemical Society 142 (14) (2020)
Bryant Chica, Jesse Ruzicka, Hayden Kallas, David W Mulder, Katherine A Brown, John W Peters, Lance C Seefeldt, Gordana Dukovic, Paul W King
Defining Intermediates of Nitrogenase MoFe Protein during N2 Reduction under Photochemical Electron Delivery from CdS Quantum Dots. Journal of the American Chemical Society 142 (33) (2020)
Dmitriy A Lukoyanov, Zhi-Yong Yang, Dennis R Dean, Lance C Seefeldt, Simone Raugei, Brian M Hoffman
Electron Redistribution within the Nitrogenase Active Site FeMo-Cofactor During Reductive Elimination of H2 to Achieve N≡N Triple-Bond Activation. Journal of the American Chemical Society 142 (52) (2020)
Emilio Jimenez-Vicente, Zhi-Yong Yang, Julia S Martin Del Campo, Valerie L Cash, Lance C Seefeldt, Dennis R Dean
The NifZ accessory protein has an equivalent function in maturation of both nitrogenase MoFe protein P-clusters. The Journal of biological chemistry 294 (16) (2019)
Veronika Hoeke, Laura Tociu, David A Case, Lance C Seefeldt, Simone Raugei, Brian M Hoffman
High-Resolution ENDOR Spectroscopy Combined with Quantum Chemical Calculations Reveals the Structure of Nitrogenase Janus Intermediate E4(4H). Journal of the American Chemical Society 141 (30) (2019)
Veronika Hoeke, Laura Tociu, David A Case, Lance C Seefeldt, Simone Raugei, Brian M Hoffman
Correction to "High-Resolution ENDOR Spectroscopy Combined with Quantum Chemical Calculations Reveals the Structure of Nitrogenase Janus Intermediate E4(4H)". Journal of the American Chemical Society 141 (50) (2019)
Dmitriy A Lukoyanov, Matthew D Krzyaniak, Dennis R Dean, Michael R Wasielewski, Lance C Seefeldt, Brian M Hoffman
Time-Resolved EPR Study of H2 Reductive Elimination from the Photoexcited Nitrogenase Janus E4(4H) Intermediate. The journal of physical chemistry. B 123 (41) (2019)
Artavazd Badalyan, Zhi-Yong Yang, Bo Hu, Jian Luo, Maowei Hu, T Leo Liu, Lance C Seefeldt
An Efficient Viologen-Based Electron Donor to Nitrogenase. Biochemistry 58 (46) (2019)
Derek F Harris, Dmitriy A Lukoyanov, Hayden Kallas, Christian Trncik, Zhi-Yong Yang, Phil Compton, Michael P Snyder, Oliver Einsle, Dennis R Dean, Brian M Hoffman, Lance C Seefeldt
Mo-, V-, and Fe-Nitrogenases Use a Universal Eight-Electron Reductive-Elimination Mechanism To Achieve N2 Reduction. Biochemistry 58 (30) (2019)
Casey Van Stappen, Roman Davydov, Zhi-Yong Yang, Ruixi Fan, Yisong Guo, Eckhard Bill, Lance C Seefeldt, Brian M Hoffman, Serena DeBeer
Spectroscopic Description of the E1 State of Mo Nitrogenase Based on Mo and Fe X-ray Absorption and Mössbauer Studies. Inorganic chemistry 58 (18) (2019)
David P Hickey, Rong Cai, Zhi-Yong Yang, Katharina Grunau, Oliver Einsle, Lance C Seefeldt, Shelley D Minteer
Establishing a Thermodynamic Landscape for the Active Site of Mo-Dependent Nitrogenase. Journal of the American Chemical Society 141 (43) (2019)
Jingguang G Chen, Richard M Crooks, Lance C Seefeldt, Kara L Bren, R Morris Bullock, Marcetta Y Darensbourg, Patrick L Holland, Brian M Hoffman, Michael J Janik, Anne K Jones, Mercouri G Kanatzidis, Paul W King, Kyle M Lancaster, Sergei V Lymar, Peter Pfromm, William F Schneider, Richard R Schrock
Beyond fossil fuel-driven nitrogen transformations. Science (New York, N.Y.) 360 (6391) (2018)
Derek F Harris, Zhi-Yong Yang, Dennis R Dean, Lance C Seefeldt, Brian M Hoffman
Kinetic Understanding of N2 Reduction versus H2 Evolution at the E4(4H) Janus State in the Three Nitrogenases. Biochemistry 57 (39) (2018)
Ziliang Mao, Shu-Hao Liou, Nimesh Khadka, Francis E Jenney, David B Goodin, Lance C Seefeldt, Michael W W Adams, Stephen P Cramer, Delmar S Larsen
Cluster-Dependent Charge-Transfer Dynamics in Iron-Sulfur Proteins. Biochemistry 57 (6) (2018)
Lance C Seefeldt, Brian M Hoffman, John W Peters, Simone Raugei, David N Beratan, Edwin Antony, Dennis R Dean
Energy Transduction in Nitrogenase. Accounts of chemical research 51 (9) (2018)
Derek F Harris, Dmitriy A Lukoyanov, Sudipta Shaw, Phil Compton, Monika Tokmina-Lukaszewska, Brian Bothner, Michael P Snyder, Dennis R Dean, Brian M Hoffman, Lance C Seefeldt
Mechanism of N2 Reduction Catalyzed by Fe-Nitrogenase Involves Reductive Elimination of H2. Biochemistry 57 (5) (2018)
Dmitriy A Lukoyanov, Nimesh Khadka, Zhi-Yong Yang, Dennis R Dean, Lance C Seefeldt, Brian M Hoffman
Hydride Conformers of the Nitrogenase FeMo-cofactor Two-Electron Reduced State E2(2H), Assigned Using Cryogenic Intra Electron Paramagnetic Resonance Cavity Photolysis. Inorganic chemistry 57 (12) (2018)
Nimesh Khadka, Ross D Milton, Sudipta Shaw, Dmitriy Lukoyanov, Dennis R Dean, Shelley D Minteer, Simone Raugei, Brian M Hoffman, Lance C Seefeldt
Mechanism of Nitrogenase H2 Formation by Metal-Hydride Protonation Probed by Mediated Electrocatalysis and H/D Isotope Effects. Journal of the American Chemical Society 139 (38) (2017)
Rhesa N Ledbetter, Amaya M Garcia Costas, Carolyn E Lubner, David W Mulder, Monika Tokmina-Lukaszewska, Jacob H Artz, Angela Patterson, Timothy S Magnuson, Zackary J Jay, H Diessel Duan, Jacquelyn Miller, Mary H Plunkett, John P Hoben, Brett M Barney, Ross P Carlson, Anne-Frances Miller, Brian Bothner, Paul W King, John W Peters, Lance C Seefeldt
The Electron Bifurcating FixABCX Protein Complex from Azotobacter vinelandii: Generation of Low-Potential Reducing Equivalents for Nitrogenase Catalysis. Biochemistry 56 (32) (2017)
Dmitriy Lukoyanov, Nimesh Khadka, Dennis R Dean, Simone Raugei, Lance C Seefeldt, Brian M Hoffman
Photoinduced Reductive Elimination of H2 from the Nitrogenase Dihydride (Janus) State Involves a FeMo-cofactor-H2 Intermediate. Inorganic chemistry 56 (4) (2017)
P Paengnakorn, Philip A Ash, S Shaw, K Danyal, T Chen, D R Dean, Lance C Seefeldt, Kylie A Vincent
Infrared spectroscopy of the nitrogenase MoFe protein under electrochemical control: potential-triggered CO binding. Chemical science 8 (2) (2016)

Lance C Seefeldt.css-eqlu8i{font-size:small;padding-left:4px;} (Lance Seefeldt, L C Seefeldt)

Publication Activity (10 Years)

Top Topics

Top Venues

Lance C Seefeldt (Lance Seefeldt, L C Seefeldt)