Comment on "Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase".

John W Peters Oliver Einsle Dennis R Dean Serena DeBeer Brian M Hoffman Patrick L Holland Lance C Seefeldt

Published in: Science (New York, N.Y.) (2021)

Kang et al (Reports, 19 June 2020, p. 1381) report a structure of the nitrogenase MoFe protein that is interpreted to indicate binding of N2 or an N2-derived species to the active-site FeMo cofactor. Independent refinement of the structure and consideration of biochemical evidence do not support this claim.

Keyphrases

binding protein
protein protein
dna binding
adverse drug
electronic health record