Lee Zou

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 34

Top Venues

Nature communications

Science advances

Science (New York, N.Y.)

Nature

Massachusetts General Hospital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital Aug 15 2004

United States

Professor :: Cancer Center

Publications

Ajinkya S Kawale, Xiaojuan Ran, Parasvi S Patel, Sneha Saxena, Michael S Lawrence, Lee Zou
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability. Science advances 10 (3) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Gaylor Boulay, Liliane C Broye, Rui Dong, Sowmya Iyer, Rajendran Sanalkumar, Yu-Hang Xing, Rémi Buisson, Shruthi Rengarajan, Beverly Naigles, Benoît Duc, Angela Volorio, Mary E Awad, Raffaele Renella, Ivan Chebib, G Petur Nielsen, Edwin Choy, Gregory M Cote, Lee Zou, Igor Letovanec, Ivan Stamenkovic, Miguel N Rivera, Nicolò Riggi
EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors. Nature communications 15 (1) (2024)
Ajinkya S Kawale, Xiaojuan Ran, Parasvi S Patel, Sneha Saxena, Michael S Lawrence, Lee Zou
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability. Science advances 10 (3) (2024)
Ajinkya S Kawale, Xiaojuan Ran, Parasvi S Patel, Sneha Saxena, Michael S Lawrence, Lee Zou
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability. Science advances 10 (3) (2024)
Ajinkya S Kawale, Xiaojuan Ran, Parasvi S Patel, Sneha Saxena, Michael S Lawrence, Lee Zou
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability. Science advances 10 (3) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Gaylor Boulay, Liliane C Broye, Rui Dong, Sowmya Iyer, Rajendran Sanalkumar, Yu-Hang Xing, Rémi Buisson, Shruthi Rengarajan, Beverly Naigles, Benoît Duc, Angela Volorio, Mary E Awad, Raffaele Renella, Ivan Chebib, G Petur Nielsen, Edwin Choy, Gregory M Cote, Lee Zou, Igor Letovanec, Ivan Stamenkovic, Miguel N Rivera, Nicolò Riggi
EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors. Nature communications 15 (1) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L Eisenhauer, Dominique Zarrella, Kate Lu, Bo R Rueda, Lee Zou, Xiaofeng A Su, Oladapo O Yeku, Leif W Ellisen, Xiao-Song Wang, Li Lan
Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair. Nature communications 15 (1) (2024)
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D Choudhury, Kent W Mouw, Zoltan Szallasi, Lee Zou, Adam S Kibel, Li Jia
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer. Nature communications 14 (1) (2023)
Hideko Isozaki, Ramin Sakhtemani, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Sunwoo Oh, Adam Langenbucher, Susanna Monroe, Wenjia Su, Heidie Frisco Cabanos, Faria M Siddiqui, Nicole Phan, Pégah Jalili, Daria Timonina, Samantha Bilton, Maria Gomez-Caraballo, Hannah L Archibald, Varuna Nangia, Kristin Dionne, Amanda K Riley, Matthew Lawlor, Mandeep Kaur Banwait, Rosemary G Cobb, Lee Zou, Nicholas J Dyson, Christopher J Ott, Cyril H Benes, Gad Getz, Chang S Chan, Alice T Shaw, Justin F Gainor, Jessica J Lin, Lecia V Sequist, Zofia Piotrowska, Beow Y Yeap, Jeffrey A Engelman, Jake June-Koo Lee, Yosef E Maruvka, Rémi Buisson, Michael S Lawrence, Aaron N Hata
Therapy-induced APOBEC3A drives evolution of persistent cancer cells. Nature (2023)
Lee Zou
Heterochromatin-dependent Replication Stress: A Lesson from IDH1/2 Mutants. Cancer research (2023)
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D Choudhury, Kent W Mouw, Zoltan Szallasi, Lee Zou, Adam S Kibel, Li Jia
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer. Nature communications 14 (1) (2023)
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D Choudhury, Kent W Mouw, Zoltan Szallasi, Lee Zou, Adam S Kibel, Li Jia
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer. Nature communications 14 (1) (2023)
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D Choudhury, Kent W Mouw, Zoltan Szallasi, Lee Zou, Adam S Kibel, Li Jia
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer. Nature communications 14 (1) (2023)
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D Choudhury, Kent W Mouw, Zoltan Szallasi, Lee Zou, Adam S Kibel, Li Jia
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer. Nature communications 14 (1) (2023)
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D Choudhury, Kent W Mouw, Zoltan Szallasi, Lee Zou, Adam S Kibel, Li Jia
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer. Nature communications 14 (1) (2023)
Marcello Stanzione, Jun Zhong, Edmond Wong, Thomas J LaSalle, Jillian F Wise, Antoine Simoneau, David T Myers, Sarah Phat, Moshe Sade-Feldman, Michael S Lawrence, M Kyle Hadden, Lee Zou, Anna F Farago, Nicholas J Dyson, Benjamin J Drapkin
Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer. Science advances 8 (19) (2022)
Chenkui Miao, Takuya Tsujino, Tomoaki Takai, Fu Gui, Takeshi Tsutsumi, Zsófia M Sztupinszki, Zengjun Wang, Haruhito Azuma, Zoltan Szallasi, Kent W Mouw, Lee Zou, Adam S Kibel, Li Jia
RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer. Science advances 8 (7) (2022)
Adam Langenbucher, Danae Bowen, Ramin Sakhtemani, Elodie Bournique, Jillian F Wise, Lee Zou, Ashok S Bhagwat, Rémi Buisson, Michael S Lawrence
An extended APOBEC3A mutation signature in cancer. Nature communications 12 (1) (2021)
Jian Ouyang, Tribhuwan Yadav, Jia-Min Zhang, Haibo Yang, Esther Rheinbay, Hongshan Guo, Daniel A Haber, Li Lan, Lee Zou
RNA transcripts stimulate homologous recombination by forming DR-loops. Nature 594 (7862) (2021)
Zhihua Kang, Pan Fu, Allen L Alcivar, Haiqing Fu, Christophe Redon, Tzeh Keong Foo, Yamei Zuo, Caiyong Ye, Ryan M Baxley, Advaitha Madireddy, Rémi Buisson, Anja-Katrin Bielinsky, Lee Zou, Zhiyuan Shen, Mirit I Aladjem, Bing Xia
BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage. Nature communications 12 (1) (2021)
Rémi Buisson, Adam Langenbucher, Danae Bowen, Eugene E Kwan, Cyril H Benes, Lee Zou, Michael S Lawrence
Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features. Science (New York, N.Y.) 364 (6447) (2020)
Seung Ho Shin, Ji Su Lee, Jia-Min Zhang, Sungbin Choi, Zarko V Boskovic, Ran Zhao, Mengqiu Song, Rui Wang, Jie Tian, Mee-Hyun Lee, Jae Hwan Kim, Minju Jeong, Jung Hyun Lee, Michael Gennadievich Petukhov, Sam W Lee, Sang Gyun Kim, Lee Zou, Sanguine Byun
Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells. Science advances 6 (31) (2020)
Hao Chen, Haibo Yang, Xiaolan Zhu, Tribhuwan Yadav, Jian Ouyang, Samuel S Truesdell, Jun Tan, Yumin Wang, Meihan Duan, Leizhen Wei, Lee Zou, Arthur S Levine, Shobha Vasudevan, Li Lan
m5C modification of mRNA serves a DNA damage code to promote homologous recombination. Nature communications 11 (1) (2020)
Hao Chen, Hao Chen, Jia-Min Zhang, Yumin Wang, Antoine Simoneau, Hui Yang, Arthur S Levine, Lee Zou, Zhijian J Chen, Li Lan
cGAS suppresses genomic instability as a decelerator of replication forks. Science advances 6 (42) (2020)
Pégah Jalili, Danae Bowen, Adam Langenbucher, Shinho Park, Kevin Aguirre, Ryan B Corcoran, Angela G Fleischman, Michael S Lawrence, Lee Zou, Rémi Buisson
Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots. Nature communications 11 (1) (2020)
Lilian Kabeche, Hai Dang Nguyen, Rémi Buisson, Lee Zou
A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation. Science (New York, N.Y.) 359 (6371) (2017)
Ching-Shyi Wu, Lee Zou
The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation. The Journal of biological chemistry 291 (1) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Lee Zou