Cyril H Benes (Cyril Benes)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Venues

Nature cancer

Nature communications

Cancer discovery

Clinical cancer research : an official journal of the American Association for Cancer Research

Massachusetts General Hospital

Universite Paris 6 (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital

United States

Principal Investigator, Assistant in Genetics :: Center for Cancer Research

Education History

Universite Paris 6 Sep 15 1989 - Mar 15 1999

France

PHD :: Biochemistry

Publications

Sanju Sinha, Rahulsimham Vegesna, Sumit Mukherjee, Ashwin V Kammula, Saugato Rahman Dhruba, Wei Wu, D Lucas Kerr, Nishanth Ulhas Nair, Matthew G Jones, Nir Yosef, Oleg V Stroganov, Ivan Grishagin, Kenneth D Aldape, Collin M Blakely, Peng Jiang, Craig J Thomas, Cyril H Benes, Trever G Bivona, Alejandro A Schäffer, Eytan Ruppin
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors. Nature cancer 5 (6) (2024)
Sanju Sinha, Rahulsimham Vegesna, Sumit Mukherjee, Ashwin V Kammula, Saugato Rahman Dhruba, Wei Wu, D Lucas Kerr, Nishanth Ulhas Nair, Matthew G Jones, Nir Yosef, Oleg V Stroganov, Ivan Grishagin, Kenneth D Aldape, Collin M Blakely, Peng Jiang, Craig J Thomas, Cyril H Benes, Trever G Bivona, Alejandro A Schäffer, Eytan Ruppin
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors. Nature cancer 5 (6) (2024)
Sanju Sinha, Rahulsimham Vegesna, Sumit Mukherjee, Ashwin V Kammula, Saugato Rahman Dhruba, Wei Wu, D Lucas Kerr, Nishanth Ulhas Nair, Matthew G Jones, Nir Yosef, Oleg V Stroganov, Ivan Grishagin, Kenneth D Aldape, Collin M Blakely, Peng Jiang, Craig J Thomas, Cyril H Benes, Trever G Bivona, Alejandro A Schäffer, Eytan Ruppin
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors. Nature cancer (2024)
Sanju Sinha, Rahulsimham Vegesna, Sumit Mukherjee, Ashwin V Kammula, Saugato Rahman Dhruba, Wei Wu, D Lucas Kerr, Nishanth Ulhas Nair, Matthew G Jones, Nir Yosef, Oleg V Stroganov, Ivan Grishagin, Kenneth D Aldape, Collin M Blakely, Peng Jiang, Craig J Thomas, Cyril H Benes, Trever G Bivona, Alejandro A Schäffer, Eytan Ruppin
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors. Nature cancer (2024)
Nishanth Ulhas Nair, Patricia Greninger, Xiaohu Zhang, Adam A Friedman, Arnaud Amzallag, Eliane Cortez, Avinash Das Sahu, Joo Sang Lee, Anahita Dastur, Regina K Egan, Ellen Murchie, Michele Ceribelli, Giovanna S Crowther, Erin Beck, Joseph McClanaghan, Carleen Klump-Thomas, Jessica L Boisvert, Leah J Damon, Kelli M Wilson, Jeffrey Ho, Angela Tam, Crystal McKnight, Sam Michael, Zina Itkin, Mathew J Garnett, Jeffrey A Engelman, Daniel A Haber, Craig J Thomas, Eytan Ruppin, Cyril H Benes
A landscape of response to drug combinations in non-small cell lung cancer. Nature communications 14 (1) (2023)
Hideko Isozaki, Ramin Sakhtemani, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Sunwoo Oh, Adam Langenbucher, Susanna Monroe, Wenjia Su, Heidie Frisco Cabanos, Faria M Siddiqui, Nicole Phan, Pégah Jalili, Daria Timonina, Samantha Bilton, Maria Gomez-Caraballo, Hannah L Archibald, Varuna Nangia, Kristin Dionne, Amanda K Riley, Matthew Lawlor, Mandeep Kaur Banwait, Rosemary G Cobb, Lee Zou, Nicholas J Dyson, Christopher J Ott, Cyril H Benes, Gad Getz, Chang S Chan, Alice T Shaw, Justin F Gainor, Jessica J Lin, Lecia V Sequist, Zofia Piotrowska, Beow Y Yeap, Jeffrey A Engelman, Jake June-Koo Lee, Yosef E Maruvka, Rémi Buisson, Michael S Lawrence, Aaron N Hata
Therapy-induced APOBEC3A drives evolution of persistent cancer cells. Nature (2023)
Nishanth Ulhas Nair, Patricia Greninger, Xiaohu Zhang, Adam A Friedman, Arnaud Amzallag, Eliane Cortez, Avinash Das Sahu, Joo Sang Lee, Anahita Dastur, Regina K Egan, Ellen Murchie, Michele Ceribelli, Giovanna S Crowther, Erin Beck, Joseph McClanaghan, Carleen Klump-Thomas, Jessica L Boisvert, Leah J Damon, Kelli M Wilson, Jeffrey Ho, Angela Tam, Crystal McKnight, Sam Michael, Zina Itkin, Mathew J Garnett, Jeffrey A Engelman, Daniel A Haber, Craig J Thomas, Eytan Ruppin, Cyril H Benes
A landscape of response to drug combinations in non-small cell lung cancer. Nature communications 14 (1) (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Nishanth Ulhas Nair, Patricia Greninger, Xiaohu Zhang, Adam A Friedman, Arnaud Amzallag, Eliane Cortez, Avinash Das Sahu, Joo Sang Lee, Anahita Dastur, Regina K Egan, Ellen Murchie, Michele Ceribelli, Giovanna S Crowther, Erin Beck, Joseph McClanaghan, Carleen Klump-Thomas, Jessica L Boisvert, Leah J Damon, Kelli M Wilson, Jeffrey Ho, Angela Tam, Crystal McKnight, Sam Michael, Zina Itkin, Mathew J Garnett, Jeffrey A Engelman, Daniel A Haber, Craig J Thomas, Eytan Ruppin, Cyril H Benes
A landscape of response to drug combinations in non-small cell lung cancer. Nature communications 14 (1) (2023)
Nishanth Ulhas Nair, Patricia Greninger, Xiaohu Zhang, Adam A Friedman, Arnaud Amzallag, Eliane Cortez, Avinash Das Sahu, Joo Sang Lee, Anahita Dastur, Regina K Egan, Ellen Murchie, Michele Ceribelli, Giovanna S Crowther, Erin Beck, Joseph McClanaghan, Carleen Klump-Thomas, Jessica L Boisvert, Leah J Damon, Kelli M Wilson, Jeffrey Ho, Angela Tam, Crystal McKnight, Sam Michael, Zina Itkin, Mathew J Garnett, Jeffrey A Engelman, Daniel A Haber, Craig J Thomas, Eytan Ruppin, Cyril H Benes
A landscape of response to drug combinations in non-small cell lung cancer. Nature communications 14 (1) (2023)
Nishanth Ulhas Nair, Patricia Greninger, Xiaohu Zhang, Adam A Friedman, Arnaud Amzallag, Eliane Cortez, Avinash Das Sahu, Joo Sang Lee, Anahita Dastur, Regina K Egan, Ellen Murchie, Michele Ceribelli, Giovanna S Crowther, Erin Beck, Joseph McClanaghan, Carleen Klump-Thomas, Jessica L Boisvert, Leah J Damon, Kelli M Wilson, Jeffrey Ho, Angela Tam, Crystal McKnight, Sam Michael, Zina Itkin, Mathew J Garnett, Jeffrey A Engelman, Daniel A Haber, Craig J Thomas, Eytan Ruppin, Cyril H Benes
A landscape of response to drug combinations in non-small cell lung cancer. Nature communications 14 (1) (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Lei Shi, William Shen, Mindy I Davis, Ke Kong, Phuong Vu, Supriya K Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D Lee, Patricia Greninger, Jonathan H Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S Crowther, Samarjit Patnaik, Matthew B Boxer, Min Shen, David Tsai Ting, William Y Kim, Ben Z Stanger, Vikram Deshpande, Cristina R Ferrone, Cyril H Benes, Wilhelm Haas, Matthew D Hall, Nabeel El-Bardeesy
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers. Nature cancer (2023)
Sheeba Jacob, Tia H Turner, Jinyang Cai, Konstantinos V Floros, Ann K Yu, Colin M Coon, Rishabh Khatri, Mohammad A Alzubi, Charles T Jakubik, Ynes M Bouck, Madhavi Puchalapalli, Mayuri Shende, Mikhail G Dozmorov, Sosipatros A Boikos, Bin Hu, J Chuck Harrell, Cyril H Benes, Jennifer E Koblinski, Carlotta Costa, Anthony C Faber
Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models. PNAS nexus 1 (5) (2022)
Qibiao Wu, Yuanli Zhen, Lei Shi, Phuong Vu, Patricia Greninger, Ramzi Adil, Joshua Merritt, Regina Egan, Meng-Ju Wu, Xunqin Yin, Cristina R Ferrone, Vikram Deshpande, Islam Baiev, Christopher J Pinto, Daniel E McLoughlin, Charlotte S Walmsley, James R Stone, John D Gordan, Andrew X Zhu, Dejan Juric, Lipika Goyal, Cyril H Benes, Nabeel Bardeesy
EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma. Cancer discovery 12 (5) (2022)
Sheeba Jacob, Tia H Turner, Jinyang Cai, Konstantinos V Floros, Ann K Yu, Colin M Coon, Rishabh Khatri, Mohammad A Alzubi, Charles T Jakubik, Ynes M Bouck, Madhavi Puchalapalli, Mayuri Shende, Mikhail G Dozmorov, Sosipatros A Boikos, Bin Hu, J Chuck Harrell, Cyril H Benes, Jennifer E Koblinski, Carlotta Costa, Anthony C Faber
Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models. PNAS nexus 1 (5) (2022)
Daniel A R Heisey, Sheeba Jacob, Timothy L Lochmann, Richard Kurupi, Maninderjit S Ghotra, Marissa L Calbert, Mayuri Shende, Yuki Kato Maves, Jennifer E Koblinski, Mikhail G Dozmorov, Sosipatros A Boikos, Cyril H Benes, Anthony C Faber
Pharmaceutical Interference of the EWS-FLI1-driven Transcriptome By Cotargeting H3K27ac and RNA Polymerase Activity in Ewing Sarcoma. Molecular cancer therapeutics 20 (10) (2021)
Krista M Dalton, Kateryna Krytska, Timothy L Lochmann, Renata Sano, Colleen Casey, Alessia D'Aulerio, Qasim A Khan, Giovanna Stein Crowther, Colin Coon, Jinyang Cai, Sheeba Jacob, Richard Kurupi, Bin Hu, Mikhail G Dozmorov, Patricia Greninger, Andrew J Souers, Cyril H Benes, Yael P Mosse, Anthony C Faber
Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma. Molecular cancer therapeutics 20 (8) (2021)
Rémi Buisson, Adam Langenbucher, Danae Bowen, Eugene E Kwan, Cyril H Benes, Lee Zou, Michael S Lawrence
Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features. Science (New York, N.Y.) 364 (6447) (2020)
Ibiayi Dagogo-Jack, Satoshi Yoda, Jochen K Lennerz, Adam Langenbucher, Jessica J Lin, Marguerite M Rooney, Kylie Prutisto-Chang, Audris Oh, Nathaniel A Adams, Beow Y Yeap, Emily Chin, Andrew Do, Hetal D Marble, Sara E Stevens, Subba R Digumarthy, Ashish Saxena, Rebecca J Nagy, Cyril H Benes, Christopher G Azzoli, Michael S Lawrence, Justin F Gainor, Alice T Shaw, Aaron N Hata
MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (11) (2020)
Carlotta Costa, Ye Wang, Amy Ly, Yasuyuki Hosono, Ellen Murchie, Charlotte S Walmsley, Tiffany Huynh, Christopher Healy, Rachel Peterson, Shogo Yanase, Charles T Jakubik, Laura E Henderson, Leah J Damon, Daria Timonina, Ioannis Sanidas, Christopher J Pinto, Mari A Mino-Kenudson, James R Stone, Nicholas J Dyson, Leif W Ellisen, Aditya Bardia, Hiromichi Ebi, Cyril H Benes, Jeffrey A Engelman, Dejan Juric
PTEN Loss Mediates Clinical Cross-Resistance to CDK4/6 and PI3Kα Inhibitors in Breast Cancer. Cancer discovery 10 (1) (2019)
Timothy L Lochmann, Krista M Powell, Jungoh Ham, Konstantinos V Floros, Daniel A R Heisey, Richard I J Kurupi, Marissa L Calbert, Maninderjit S Ghotra, Patricia Greninger, Mikhail G Dozmorov, Madhu Gowda, Andrew J Souers, C Patrick Reynolds, Cyril H Benes, Anthony C Faber
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma. Science translational medicine 10 (441) (2019)
Lipika Goyal, Lei Shi, Leah Y Liu, Ferran Fece de la Cruz, Jochen K Lennerz, Srivatsan Raghavan, Ignaty Leschiner, Liudmila Elagina, Giulia Siravegna, Raymond W S Ng, Phuong Vu, Krushna C Patra, Supriya K Saha, Raul N Uppot, Ron Arellano, Stephanie Reyes, Takeshi Sagara, Sachie Otsuki, Brandon A Nadres, Heather A Shahzade, Ipsita Dey-Guha, Isobel J Fetter, Islam Baiev, Emily E Van Seventer, Janet E Murphy, Cristina R Ferrone, Kenneth K Tanabe, Vikram Deshpande, James J Harding, Rona Yaeger, Robin K Kelley, Alberto Bardelli, A John Iafrate, William C Hahn, Cyril H Benes, David Tsai Ting, Hiroshi Hirai, Gad A Getz, Dejan Juric, Andrew X Zhu, Ryan B Corcoran, Nabeel Bardeesy
TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma. Cancer discovery 9 (8) (2019)
Sean P Brown, Brian Belmontes, Gordon Moody, Kathleen S Keegan, Danny Chui, Douglas A Whittington, David Ching Siang Huang, Leszek Poppe, Alan C Cheng, Mario Cardozo, Jonathan Houze, Yunxiao Li, Brian Lucas, Nick A Paras, Xianghong Wang, Joshua P Taygerly, Marc Vimolratana, Manuel Zancanella, Liusheng Zhu, Elaina Cajulis, Tao Osgood, Jan Sun, Leah J Damon, Regina K Egan, Patricia Greninger, Joseph D McClanaghan, Jianan Gong, Donia Moujalled, Giovanna Pomilio, Pedro Beltran, Cyril H Benes, Andrew W Roberts, Andrew Wei, Jude Canon, Angela Coxon, Paul E Hughes
AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies. Cancer discovery 8 (12) (2018)
Daniel A R Heisey, Timothy L Lochmann, Konstantinos V Floros, Colin M Coon, Krista M Powell, Sheeba Jacob, Marissa L Calbert, Maninderjit S Ghotra, Giovanna T Stein, Yuki Kato Maves, Steven Christopher Smith, Cyril H Benes, Joel D Leverson, Andrew J Souers, Sosipatros A Boikos, Anthony C Faber
The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (5) (2018)
Varuna Nangia, Faria M Siddiqui, Sean Caenepeel, Daria Timonina, Samantha J Bilton, Nicole Phan, Maria Gomez-Caraballo, Hannah L Archibald, Chendi Li, Cameron Fraser, Diamanda Rigas, Kristof Vajda, Lorin A Ferris, Michael Lanuti, Cameron D Wright, Kevin A Raskin, Daniel P Cahill, John H Shin, Colleen Keyes, Lecia V Sequist, Zofia Piotrowska, Anna F Farago, Christopher G Azzoli, Justin F Gainor, Kristopher A Sarosiek, Sean P Brown, Angela Coxon, Cyril H Benes, Paul E Hughes, Aaron N Hata
Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non-Small Cell Lung Cancer. Cancer discovery 8 (12) (2018)
Anahita Dastur, AHyun Choi, Carlotta Costa, Xunqin Yin, August Williams, Joseph McClanaghan, Max Greenberg, Justine Roderick, Neha U Patel, Jessica Boisvert, Ultan McDermott, Mathew J Garnett, Jorge Almenara, Steven Grant, Kathryn Rizzo, Jeffrey A Engelman, Michelle Kelliher, Anthony C Faber, Cyril H Benes
NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (1) (2018)
Sandra Misale, Jackson P Fatherree, Eliane Cortez, Chendi Li, Samantha Bilton, Daria Timonina, David T Myers, Dana Lee, Maria Gomez-Caraballo, Max Greenberg, Varuna Nangia, Patricia Greninger, Regina K Egan, Joseph McClanaghan, Giovanna T Stein, Ellen Murchie, Patrick P Zarrinkar, Matthew R Janes, Lian-Sheng Li, Yi Liu, Aaron N Hata, Cyril H Benes
KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (2) (2018)

Cyril H Benes.css-eqlu8i{font-size:small;padding-left:4px;} (Cyril Benes)

Publication Activity (10 Years)

Top Topics

Top Venues

Cyril H Benes (Cyril Benes)