Lei Chen

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 32

Top Venues

Nature communications

Nature

BioEssays : news and reviews in molecular, cellular and developmental biology

Biochemistry

Peking University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Peking University Mar 29 2016

China

Investigator :: Institute of Molecular Medicine

Publications

Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature (2024)
Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature 627 (8002) (2024)
Tianyi Hou, Lei Chen
Sulfonylurea receptor 2 (SUR2), intricate sensors for intracellular Mg-nucleotides. BioEssays : news and reviews in molecular, cellular and developmental biology 46 (3) (2024)
Tianyi Hou, Lei Chen
Sulfonylurea receptor 2 (SUR2), intricate sensors for intracellular Mg-nucleotides. BioEssays : news and reviews in molecular, cellular and developmental biology 46 (3) (2024)
Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature 627 (8002) (2024)
Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature 627 (8002) (2024)
Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature (2024)
Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature 627 (8002) (2024)
Tianyi Hou, Lei Chen
Sulfonylurea receptor 2 (SUR2), intricate sensors for intracellular Mg-nucleotides. BioEssays : news and reviews in molecular, cellular and developmental biology (2024)
Xiaoyu Liu, Yiting Shi, Rui Liu, Kangcheng Song, Lei Chen
Structure of human phagocyte NADPH oxidase in the activated state. Nature (2024)
Tianyi Hou, Lei Chen
Sulfonylurea receptor 2 (SUR2), intricate sensors for intracellular Mg-nucleotides. BioEssays : news and reviews in molecular, cellular and developmental biology 46 (3) (2024)
Yunlu Kang, Lei Chen
Structural basis for the binding of DNP and purine nucleotides onto UCP1. Nature (2023)
Wenhao Cui, Yange Niu, Zejian Sun, Rui Liu, Lei Chen
Structures of human SGLT in the occluded state reveal conformational changes during sugar transport. Nature communications 14 (1) (2023)
Dian Ding, Tianyi Hou, Miao Wei, Jing-Xiang Wu, Lei Chen
The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nature communications 14 (1) (2023)
Dian Ding, Jing-Xiang Wu, Xinli Duan, Songling Ma, Lipeng Lai, Lei Chen
Structural identification of vasodilator binding sites on the SUR2 subunit. Nature communications 13 (1) (2022)
Yunlu Kang, Lei Chen
Structure and mechanism of NALCN-FAM155A-UNC79-UNC80 channel complex. Nature communications 13 (1) (2022)
Rui Liu, Kangcheng Song, Jing-Xiang Wu, Xiao-Peng Geng, Liming Zheng, Xiaoyin Gao, Hailin Peng, Lei Chen
Structure of human phagocyte NADPH oxidase in the resting state. eLife 11 (2022)
Yaxiong Yang, Miao Wei, Lei Chen
Structural identification of riluzole-binding site on human TRPC5. Cell discovery 8 (1) (2022)
Wenhao Cui, Yange Niu, Lei Chen
The Protein Fusion Strategy Facilitates the Structure Determination of Small Membrane Proteins by Cryo-EM. Biochemistry (2022)
Mengmeng Wang, Jing-Xiang Wu, Dian Ding, Lei Chen
Structural insights into the mechanism of pancreatic K ATP channel regulation by nucleotides. Nature communications 13 (1) (2022)
Yange Niu, Wenhao Cui, Rui Liu, Sanshan Wang, Han Ke, Xiaoguang Lei, Lei Chen
Structural mechanism of SGLT1 inhibitors. Nature communications 13 (1) (2022)
Yange Niu, Gengjia Chen, Fengxiang Lv, Rui-Ping Xiao, Xinli Hu, Lei Chen
Cryo-EM structure of human MG53 homodimer. The Biochemical journal 479 (17) (2022)
Jing-Xiang Wu, Dian Ding, Lei Chen
The Emerging Structural Pharmacology of ATP-Sensitive Potassium Channels. Molecular pharmacology 102 (5) (2022)
Rui Liu, Yunlu Kang, Lei Chen
Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nature communications 12 (1) (2021)
Jing-Xiang Wu, Rui Liu, Kangcheng Song, Lei Chen
Structures of human dual oxidase 1 complex in low-calcium and high-calcium states. Nature communications 12 (1) (2021)
Kangcheng Song, Miao Wei, Wenjun Guo, Li Quan, Yunlu Kang, Jing-Xiang Wu, Lei Chen
Structural basis for human TRPC5 channel inhibition by two distinct inhibitors. eLife 10 (2021)
Yange Niu, Rui Liu, Chengcheng Guan, Yuan Zhang, Zhixing Chen, Stefan Hoerer, Herbert Nar, Lei Chen
Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter. Nature (2021)
Chengcheng Guan, Yange Niu, Si-Cong Chen, Yunlu Kang, Jing-Xiang Wu, Koji Nishi, Catherine C Y Chang, Ta-Yuan Chang, Tuoping Luo, Lei Chen
Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nature communications 11 (1) (2020)
Yunlu Kang, Jing-Xiang Wu, Lei Chen
Structure of voltage-modulated sodium-selective NALCN-FAM155A channel complex. Nature communications 11 (1) (2020)
Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Lei Chen
Structural Insights into the Inhibitory Mechanism of Insulin Secretagogues on the Pancreatic ATP-Sensitive Potassium Channel. Biochemistry 59 (1) (2019)
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen
Structure of the receptor-activated human TRPC6 and TRPC3 ion channels. Cell research 28 (7) (2018)
Mingfeng Zhang, Dali Wang, Yunlu Kang, Jing-Xiang Wu, Fuqiang Yao, Chengfang Pan, Zhiqiang Yan, Chen Song, Lei Chen
Structure of the mechanosensitive OSCA channels. Nature structural & molecular biology 25 (9) (2018)

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Publication Activity (10 Years)

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Lei Chen