Molecular pharmacology

Keyphrases

Publications

2023

Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase (FAAH) Ameliorates Cisplatin-induced Nephropathy in Mice . Molecular pharmacology (2023)
Caroline de Almeida Freitas Accioli, Michelle Sabrina da Silva, Bianca Aloise Maneira Corrêa Santos, Carlos Rangel Rodrigues
Aryl hydrocarbon receptor as a therapeutical target of environmentally induced skin conditions . Molecular pharmacology (2023)
Yutaro Ohno, Michihiko Suzuki, Hidetsugu Asada, Tomoyuki Kanda, Mayumi Saki, Hikaru Miyagi, Mai Yasunaga, Chiyo Suno, So Iwata, Jun-Ichi Saito, Shinichi Uchida
In vitro pharmacological profile of KW-6356, a novel adenosine A 2A receptor antagonist/inverse agonist. Molecular pharmacology (2023)
Sooyeon Jo, Han-Xiong Bear Zhang, Bruce P Bean
Use-dependent relief of inhibition of Nav1.8 channels by A-887826 . Molecular pharmacology (2023)
Gernot Langer, John Scott, Christoffer Lind, Christiane Otto, Ulrich Bothe, Alexis Laux-Biehlmann, Jörg Müller, Beau le Roy, Horst Irlbacher, Katrin Nowak-Reppel, Anne Schlüter, Adam J Davenport, Mark Slack, Stefan Bäurle
Discovery and in vitro Characterization of BAY 2686013, an Allosteric Small Molecule Antagonist of the Human PAC 1 Receptor. Molecular pharmacology (2023)
Yutaro Ohno, Michihiko Suzuki, Hidetsugu Asada, Tomoyuki Kanda, Mayumi Saki, Hikaru Miyagi, Mai Yasunaga, Chiyo Suno, So Iwata, Jun-Ichi Saito, Shinichi Uchida
In vitro pharmacological profile of KW-6356, a novel adenosine A 2A receptor antagonist/inverse agonist. Molecular pharmacology (2023)
Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I Nicely, Luke Pardy, Yanfang Huang, Peter Shaw, Gregory Auner, Alex Dickson, Manohar Ratnam
The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain . Molecular pharmacology (2023)
Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi, Takeshi Inukai
CRISPR/Cas9-mediated induction of relapse-specific NT5C2 and PRPS1 mutations confers thiopurine resistance as a relapsed lymphoid leukemia model . Molecular pharmacology (2023)
Ashwin Muraleetharan, Yuyang Wang, Matthew C Rowe, Ashleigh Gould, Karen J Gregory, Shane D Hellyer
Rigorous characterisation of allosteric modulation of the human metabotropic glutamate receptor 1 reveals probe and assay dependent pharmacology. Molecular pharmacology (2023)
Sooyeon Jo, Han-Xiong Bear Zhang, Bruce P Bean
Use-dependent relief of inhibition of Nav1.8 channels by A-887826 . Molecular pharmacology (2023)
Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu, KeWei Wang
A novel role of uricosuric agent benzbromarone in BK channel activation and reduction of airway smooth muscle contraction . Molecular pharmacology (2023)
Barbara Wardas, Jochen G Schneider, Norbert Klugbauer, Veit Flockerzi, Andreas Beck
Englerin A inhibits T-type CaV channels at low-micromolar concentrations. Molecular pharmacology (2023)
Marie Taniguchi, Sai Yasukochi, Wakaba Yamakawa, Yuya Tsurudome, Akito Tsuruta, Michiko Horiguchi, Kentaro Ushijima, Tomohiro Yamashita, Naoya Shindo, Akio Ojida, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo
Inhibition of tumor-derived CCL2 expression attenuates tactile allodynia in NCTC 2472 fibrosarcoma-inoculated mice. Molecular pharmacology (2023)
Xia Lei, Christopher Hofmann, Alice L Rodriguez, Colleen M Niswender
Differential Activity of Orthosteric Agonists and Allosteric Modulators at Metabotropic Glutamate Receptor 7. Molecular pharmacology (2023)
Xia Lei, Christopher Hofmann, Alice L Rodriguez, Colleen M Niswender
Differential Activity of Orthosteric Agonists and Allosteric Modulators at Metabotropic Glutamate Receptor 7. Molecular pharmacology (2023)
Hugo R Arias, Spencer R Pierce, Allison L Germann, Sophia Q Xu, Marcelo O Ortells, Seiji Sakamoto, Dina Manetti, Maria Novella Romanelli, Itaru Hamachi, Gustav Akk
Chemical, Pharmacological, and Structural Characterization of Novel Acrylamide-Derived Modulators of the GABA A Receptor . Molecular pharmacology (2023)
Vi Pham, Maria Clazina Cornelia Habben Jansen, Geoff Thompson, Laura H Heitman, Arthur Christopoulos, David M Thal, Celine Valant
Role of conserved tyrosine lid residues in the activation of the M 2 muscarinic acetylcholine receptor. Molecular pharmacology (2023)
Wallace K B Chan, Heather A Carlson, John R Traynor
Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G-protein-Coupled Receptors . Molecular pharmacology (2023)
Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi, Takeshi Inukai
CRISPR/Cas9-mediated induction of relapse-specific NT5C2 and PRPS1 mutations confers thiopurine resistance as a relapsed lymphoid leukemia model . Molecular pharmacology (2023)
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase (FAAH) Ameliorates Cisplatin-induced Nephropathy in Mice . Molecular pharmacology (2023)
Mariana Lemos Duarte, Minghui Wang, Ivone Gomes, Chenge Liu, Ali Sharma, Amanda K Fakira, Achla Gupta, Seshat M Mack, Bin Zhang, Lakshmi A Devi
Multi-omics analyses identify PREPL as a key regulator of protein trafficking, a pathway underlying Alzheimer's disease pathogenesis . Molecular pharmacology (2023)
Wataru Koizumi, Shuya Otsubo, Shogo Furutani, Kunihiro Niki, Koichi Takayama, Shota Fujimura, Takanobu Maekawa, Ryosuke Koyari, Makoto Ihara, Kenji Kai, Hideo Hayashi, Mohammad Shaokat Ali, Eriko Kage-Nakadai, David B Sattelle, Kazuhiko Matsuda
Determinants of subtype-selectivity of the anthelmintic paraherquamide A on Caenorhabditis elegans nicotinic acetylcholine receptors . Molecular pharmacology (2023)
Yue Dai, Dennis J Stuehr
BAY58-2667 activates different sGC species by distinct mechanisms that indicate its principal target in cells is the heme-free sGCβ-Hsp90 complex . Molecular pharmacology (2023)
Chaseley E McKenzie, Andrew Hung, A Marie Phillips, Ming S Soh, Christopher A Reid, Ian C Forster
The potential antidepressant compound Org 34167 modulates HCN channels via a novel mode of action. Molecular pharmacology (2023)
Alexander L Vizurraga, Michael J Robertson, Maiya Yu, Georgios Skiniotis, Gregory G Tall
Hexahydroquinoline Derivatives are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56. Molecular pharmacology (2023)
Tonibelle Gatbonton-Schwager, Yoko Yagishita, Tanvi Joshi, Nobunao Wakabayashi, Harini Srinivasan, Takafumi Suzuki, Masayuki Yamamoto, Thomas W Kensler
A Point Mutation at C151 of Keap1 of Mice Abrogates NRF2 Signaling, Cytoprotection In Vitro and Hepatoprotection In Vivo by Bardoxolone Methyl (CDDO-Me) . Molecular pharmacology (2023)
Caroline de Almeida Freitas Accioli, Michelle Sabrina da Silva, Bianca Aloise Maneira Corrêa Santos, Carlos Rangel Rodrigues
Aryl hydrocarbon receptor as a therapeutical target of environmentally induced skin conditions . Molecular pharmacology (2023)
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase (FAAH) Ameliorates Cisplatin-induced Nephropathy in Mice . Molecular pharmacology (2023)
Sooyeon Jo, Han-Xiong Bear Zhang, Bruce P Bean
Use-dependent relief of inhibition of Nav1.8 channels by A-887826 . Molecular pharmacology (2023)
Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu, KeWei Wang
A novel role of uricosuric agent benzbromarone in BK channel activation and reduction of airway smooth muscle contraction . Molecular pharmacology (2023)
Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I Nicely, Luke Pardy, Yanfang Huang, Peter Shaw, Gregory Auner, Alex Dickson, Manohar Ratnam
The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain . Molecular pharmacology (2023)
Noah Campagna, Erika Wall, Kevin Lee, Jun Guo, Wentao Li, Tonghua Yang, Adrian Baranchuk, Mohammad El Diasty, Shetuan Zhang
Differential effects of remdesivir and lumacaftor on homomeric and heteromeric hERG channels. Molecular pharmacology (2023)
Qianru Zhao, Xu Zhang, Siru Long, Shaobing Wang, Hui Yu, Yongsheng Zhou, Yi Li, Lu Xue, Yan Hu, Shijin Yin
Licochalcone Mediates the Pain Relief by Targeting the Voltage-Gated Sodium Channel . Molecular pharmacology (2023)
DanDan Geng, Yaning Li, Rong Zheng, Runmeng Wang, Bo Yang, Huaxing Zhang, Yang Zhang, Fan Zhang
Modulation of Kv7 Channel Currents by Echinocystic Acid . Molecular pharmacology (2023)
Maria Constanza Maldifassi, Hugo Rego Campello, Timothy Gallagher, Henry A Lester, Dennis A Dougherty
Human α6β4 nicotinic acetylcholine receptor: heterologous expression and agonist behavior provide insights into the immediate binding site. Molecular pharmacology (2023)
Toru Hosoi, Kyosuke Yazawa, Michihiro Imada, Akari Tawara, Chihiro Tohda, Yasuyuki Nomura, Koichiro Ozawa
Alkannin attenuates amyloid β aggregation and Alzheimer's disease pathology . Molecular pharmacology (2023)
Wallace K B Chan, Heather A Carlson, John R Traynor
Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G-protein-Coupled Receptors . Molecular pharmacology (2023)

volume 103, number 4, 2023

Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu, KeWei Wang
A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction. Molecular pharmacology 103 (4) (2023)
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin L Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice. Molecular pharmacology 103 (4) (2023)
Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi, Takeshi Inukai
CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model. Molecular pharmacology 103 (4) (2023)
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin L Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice. Molecular pharmacology 103 (4) (2023)
Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu, KeWei Wang
A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction. Molecular pharmacology 103 (4) (2023)
Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I Nicely, Luke Pardy, Yanfang Huang, Peter E Shaw, Gregory Auner, Alex Dickson, Manohar Ratnam
The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-Terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain. Molecular pharmacology 103 (4) (2023)
Sooyeon Jo, Han-Xiong Bear Zhang, Bruce P Bean
Use-Dependent Relief of Inhibition of Nav1.8 Channels by A-887826. Molecular pharmacology 103 (4) (2023)
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin L Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice. Molecular pharmacology 103 (4) (2023)
Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I Nicely, Luke Pardy, Yanfang Huang, Peter E Shaw, Gregory Auner, Alex Dickson, Manohar Ratnam
The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-Terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain. Molecular pharmacology 103 (4) (2023)
Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi, Takeshi Inukai
CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model. Molecular pharmacology 103 (4) (2023)
Sooyeon Jo, Han-Xiong Bear Zhang, Bruce P Bean
Use-Dependent Relief of Inhibition of Nav1.8 Channels by A-887826. Molecular pharmacology 103 (4) (2023)
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin L Poklis, Brandon Em, David A Gewirtz, Aron H Lichtman, Ningjun Li
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice. Molecular pharmacology 103 (4) (2023)
Sooyeon Jo, Han-Xiong Bear Zhang, Bruce P Bean
Use-Dependent Relief of Inhibition of Nav1.8 Channels by A-887826. Molecular pharmacology 103 (4) (2023)