Lesetja J Legoabe (Lereze Marais)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 19

Top Topics

Structure Activity Relationship

Ankylosing Spondylitis

Mycobacterium Tuberculosis

Top Venues

Chemical biology & drug design

Molecular diversity

Molecules (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Devesh S Agarwal, Richard M Beteck, Kayhan Ilbeigi, Guy Caljon, Lesetja J Legoabe
Design and synthesis of imidazo[1,2-a]pyridine-chalcone conjugates as antikinetoplastid agents. Chemical biology & drug design (2023)
Koketso J Setshedi, Richard M Beteck, Omobolanle J Jesumoroti, Kayhan Ilbeigi, Dorien Mabille, Guy Caljon, Frank Van der Kooy, Lesetja J Legoabe
2-Aroyl quinazolinone: Synthesis and in vitro anti-parasitic activity. Chemical biology & drug design (2023)
Omobolanle Janet Jesumoroti, Richard M Beteck, Audrey Jordaan, Digby Francis Warner, Lesetja J Legoabe
Exploration of 4-aminopyrrolo[2,3-d]pyrimidine as antitubercular agents. Molecular diversity (2022)
Charné du Preez, Lesetja J Legoabe, Audrey Jordaan, Omobolanle J Jesumoroti, Digby F Warner, Richard M Beteck
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation. Chemical biology & drug design (2022)
Mohamad Fawzi Mahomodally, Muhammad Zakariyyah Aumeeruddy, Lesetja J Legoabe, Domenico Montesano, Muhammad Imran Tousif
Nigella sativa L. and Its Active Compound Thymoquinone in the Clinical Management of Diabetes: A Systematic Review. International journal of molecular sciences 23 (20) (2022)
Chrisna Matthee, David D N'Da, Lesetja J Legoabe, Helena D Janse van Rensburg
Correction to: Exploration of chalcones and related heterocycle compounds as ligands of adenosine receptors: therapeutics development. Molecular diversity (2021)
Chrisna Matthee, Gisella Terre'Blanche, Helena D Janse van Rensburg, Janine Aucamp, Lesetja J Legoabe
Chalcone-inspired rA1 /A2A adenosine receptor ligands: ring closure as an alternative to a reactive substructure. Chemical biology & drug design (2021)
Chrisna Matthee, David D N'Da, Lesetja J Legoabe, Helena D Janse van Rensburg
Exploration of chalcones and related heterocycle compounds as ligands of adenosine receptors: therapeutics development. Molecular diversity (2021)
Augustine A Ahmadu, Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis A Lawal, Aniefiok Udobre, Blandine Baratte, Camilla Triscornia, Axelle Autret, Thomas Robert, Jeannette Chloë Bulinski, Morgane Rousselot, Mélanie Simoes Eugénio, Marie-Thérèse Dimanche-Boitrel, Jacobus P Petzer, Lesetja J Legoabe, Stéphane Bach
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor. Molecules (Basel, Switzerland) 26 (15) (2021)
Klaudia T Angula, Lesetja J Legoabe, Richard M Beteck
Chemical Classes Presenting Novel Antituberculosis Agents Currently in Different Phases of Drug Development: A 2010-2020 Review. Pharmaceuticals (Basel, Switzerland) 14 (5) (2021)
Nadia Janse van Vuuren, Helena D Janse van Rensburg, David D N'Da, Lesetja J Legoabe
New fused pyrroles with rA1/A2A antagonistic activity as potential therapeutics for neurodegenerative disorders. Molecular diversity (2021)
Richard M Beteck, Audrey Jordaan, Tarryn Swart, Frank Van Der Kooy, Digby F Warner, Heinrich C Hoppe, Lesetja J Legoabe
6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity. Chemical biology & drug design 96 (6) (2020)
Malikotsi A Qhobosheane, Lesetja J Legoabe, Béatrice Josselin, Stéphane Bach, Sandrine Ruchaud, Richard M Beteck
Synthesis and evaluation of C3 substituted chalcone-based derivatives of 7-azaindole as protein kinase inhibitors. Chemical biology & drug design 96 (6) (2020)
Helena D Janse van Rensburg, Lesetja J Legoabe, David D N'Da
C3 amino-substituted chalcone derivative with selective adenosine rA1 receptor affinity in the micromolar range. Chemicke zvesti (2020)
Chantalle Moolman, Rencia van der Sluis, Richard M Beteck, Lesetja J Legoabe
An Update on Development of Small-Molecule Plasmodial Kinase Inhibitors. Molecules (Basel, Switzerland) 25 (21) (2020)
Richard M Beteck, Ronnett Seldon, Audrey Jordaan, Digby Francis Warner, Heinrich C Hoppe, Dustin Laming, Lesetja J Legoabe, Setshaba D Khanye
Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation. MedChemComm 10 (2) (2019)
Lesetja J Legoabe, Anél Petzer, Jacobus P Petzer, Lesetja J Legoabe
The monoamine oxidase inhibition properties of C6- and N1-substituted 3-methyl-3,4-dihydroquinazolin-2(1H)-one derivatives. Molecular diversity 24 (2) (2019)
Helena D Janse van Rensburg, Lesetja J Legoabe, David D N'Da, Mietha Magdalena van der Walt
Methoxy substituted 2-benzylidene-1-indanone derivatives as A1 and/or A2A AR antagonists for the potential treatment of neurological conditions. MedChemComm 10 (2) (2019)
Lesetja J Legoabe, Mietha M Van der Walt, Gisella Terre'Blanche
Evaluation of 2-benzylidene-1-tetralone derivatives as antagonists of A1 and A2A adenosine receptors. Chemical biology & drug design 91 (1) (2017)