Leslie N Aldrich (L N Aldrich)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 13

Top Topics

Endoplasmic Reticulum Stress

Top Venues

Journal of natural products

Nature chemical biology

SLAS discovery : advancing life sciences R & D

This page only lists publications with an associated author ORCID identifier.

Publications

Amanda C Maldonado, Monica A Haughan, Manead Khin, Julia Ekiert, Ziwei Zhang, Daniel Lantvit, Zeinab Al Subeh, Herma C Pierre, Maryna Salkovski, Tal Hirschhorn, Yu Gao, Cedric J Pearce, Brent R Stockwell, Leslie N Aldrich, Nicholas H Oberlies, Joanna E Burdette
Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models. Journal of natural products (2023)
Ryan S Hippman, Amanda M Snead, Zoe A Petros, Melissa A Korkmaz, Sruchi Patel, Daniel Sotelo, Andrew Dobria, Maryna Salkovski, Thu T A Nguyen, Ricardo Linares, Stephanie M Cologna, Swetha Gowrishankar, Leslie N Aldrich
Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons. ACS chemical neuroscience (2023)
Leslie N Aldrich, Joanna E Burdette, Esperanza Carcache de Blanco, Christopher C Coss, Alessandra S Eustáquio, Joanna E Burdette, Alan Douglas Kinghorn, Amanda MacFarlane, Brittney K Mize, Nicholas H Oberlies, Jimmy E Orjala, Cedric J Pearce, Mitch A Phelps, Liva Harinantenaina Rakotondraibe, Yulin Ren, Djaja Doel Soejarto, Brent R Stockwell, Jack C Yalowich, Xiaoli Zhang
Discovery of Anticancer Agents of Diverse Natural Origin. Journal of natural products 85 (3) (2022)
Amrita Salvi, Alexandria N Young, Andrew C Huntsman, Melissa R Pergande, Melissa A Korkmaz, Rathnayake A Rathnayake, Brittney K Mize, A Douglas Kinghorn, Xiaoli Zhang, Kiira Ratia, Markus Schirle, Jason R Thomas, Scott M Brittain, Claude Shelton, Leslie N Aldrich, Stephanie M Cologna, James R Fuchs, Joanna E Burdette
PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell death & disease 13 (1) (2022)
Maryna Salkovski, Ivan Pavlinov, Qiwen Gao, Leslie N Aldrich
Development of a High-Throughput, Compound-Multiplexed Fluorescence Polarization Assay to Identify ATG5-ATG16L1 Protein-Protein Interaction Inhibitors. SLAS discovery : advancing life sciences R & D 26 (7) (2021)
Ryan S Hippman, Ivan Pavlinov, Qiwen Gao, Michelle K Mavlyanova, Erica M Gerlach, Leslie N Aldrich
Multiple Chemical Features Impact Biological Performance Diversity of a Highly Active Natural Product-Inspired Library. Chembiochem : a European journal of chemical biology 21 (21) (2020)
Ivan Pavlinov, Maryna Salkovski, Leslie N Aldrich
Beclin 1-ATG14L Protein-Protein Interaction Inhibitor Selectively Inhibits Autophagy through Disruption of VPS34 Complex I. Journal of the American Chemical Society 142 (18) (2020)
I Pavlinov, M Salkovski, Leslie N Aldrich
Selective autophagy inhibition through disruption of the PIK3C3-containing complex I. Autophagy 16 (8) (2020)
Biji Mathew, Mohansrinivas Chennakesavalu, Monica Sharma, Leianne A Torres, Clara R Stelman, Sophie Tran, Raj Patel, Nathan Burg, Maryna Salkovski, Konrad Kadzielawa, Figen Seiler, Leslie N Aldrich, Steven Roth
Autophagy and post-ischemic conditioning in retinal ischemia. Autophagy 17 (6) (2020)
Leslie N Aldrich
Lipids lead the way. Nature chemical biology 15 (7) (2019)
Erica M Gerlach, Melissa A Korkmaz, Ivan Pavlinov, Qiwen Gao, Leslie N Aldrich
Systematic Diversity-Oriented Synthesis of Reduced Flavones from γ-Pyrones to Probe Biological Performance Diversity. ACS chemical biology 14 (7) (2019)
Alexandria N Young, Denisse Herrera, Andrew C Huntsman, Melissa A Korkmaz, Daniel D Lantvit, Sarmistha Mazumder, Shamalatha Kolli, Christopher C Coss, Salane King, Hongyan Wang, Steven M Swanson, A Douglas Kinghorn, Xiaoli Zhang, Mitch A Phelps, Leslie N Aldrich, James R Fuchs, Joanna E Burdette
Phyllanthusmin Derivatives Induce Apoptosis and Reduce Tumor Burden in High-Grade Serous Ovarian Cancer by Late-Stage Autophagy Inhibition. Molecular cancer therapeutics 17 (10) (2018)
Travis R Helgren, Lianyan L Xu, Daniel Sotelo, Yash R Mehta, Melissa A Korkmaz, Ivan Pavlinov, Leslie N Aldrich
Microwave-Assisted, Asymmetric Synthesis of 3-Amino-2,3-Dihydrobenzofuran Flavonoid Derivatives from Chalcones. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (18) (2018)