Liangxue Lai

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 30

Top Venues

Nucleic acids research

Nature genetics

Cells

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Jiangshan Xu, Pengcheng Guo, Shijie Hao, Shuncheng Shangguan, Quan Shi, Giacomo Volpe, Keke Huang, Jing Zuo, Juan An, Yue Yuan, Mengnan Cheng, Qiuting Deng, Xiao Zhang, Guangyao Lai, Haitao Nan, Baihua Wu, Xinyi Shentu, Liang Wu, Xiaoyu Wei, Yujia Jiang, Xin Huang, Fengyu Pan, Yumo Song, Ronghai Li, Zhifeng Wang, Chuanyu Liu, Shi-Ping Liu, Yuxiang Li, Tao Yang, Zhicheng Xu, Wensi Du, Ling Li, Tanveer Ahmed, Kai You, Zhen Dai, Li Li, Baoming Qin, Yin-Xiong Li, Liangxue Lai, Dajiang Qin, Junling Chen, Rong Fan, Yongyin Li, Jin-Lin Hou, Michael Ott, Amar Deep Sharma, Tobias Cantz, Axel Schambach, Karsten Kristiansen, Andrew P Hutchins, Berthold Göttgens, Patrick H Maxwell, Lijian Hui, Xue Liu, Longqi Liu, Ao Chen, Yiwei Lai, Miguel Angel Esteban
A spatiotemporal atlas of mouse liver homeostasis and regeneration. Nature genetics 56 (5) (2024)
Weikai Ge, Shixue Gou, Xiaozhu Zhao, Qin Jin, Zhenpeng Zhuang, Yu Zhao, Yanhui Liang, Zhen Ouyang, Xiaoyi Liu, Fangbing Chen, Hui Shi, Haizhao Yan, Han Wu, Liangxue Lai, Kepin Wang
In vivo evaluation of guide-free Cas9-induced safety risks in a pig model. Signal transduction and targeted therapy 9 (1) (2024)
Jinze Li, Ding Zhao, Tao Zhang, Haoyang Xiong, Mingyang Hu, Hongmei Liu, Feiyu Zhao, Xiaodi Sun, Peng Fan, Yuqiang Qian, Di Wang, Liangxue Lai, Tingting Sui, Zhanjun Li
Precise large-fragment deletions in mammalian cells and mice generated by dCas9-controlled CRISPR/Cas3. Science advances 10 (11) (2024)
Weikai Ge, Shixue Gou, Xiaozhu Zhao, Qin Jin, Zhenpeng Zhuang, Yu Zhao, Yanhui Liang, Zhen Ouyang, Xiaoyi Liu, Fangbing Chen, Hui Shi, Haizhao Yan, Han Wu, Liangxue Lai, Kepin Wang
In vivo evaluation of guide-free Cas9-induced safety risks in a pig model. Signal transduction and targeted therapy 9 (1) (2024)
Degong Ruan, Yiyi Xuan, Timothy Theodore Ka Ki Tam, ZhuoXuan Li, Xiao Wang, Shao Xu, Doris Herrmann, Heiner Niemann, Liangxue Lai, Xuefei Gao, Monika Nowak-Imialek, Pengtao Liu
An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells. Nature protocols (2024)
Weikai Ge, Shixue Gou, Xiaozhu Zhao, Qin Jin, Zhenpeng Zhuang, Yu Zhao, Yanhui Liang, Zhen Ouyang, Xiaoyi Liu, Fangbing Chen, Hui Shi, Haizhao Yan, Han Wu, Liangxue Lai, Kepin Wang
In vivo evaluation of guide-free Cas9-induced safety risks in a pig model. Signal transduction and targeted therapy 9 (1) (2024)
Jiangshan Xu, Pengcheng Guo, Shijie Hao, Shuncheng Shangguan, Quan Shi, Giacomo Volpe, Keke Huang, Jing Zuo, Juan An, Yue Yuan, Mengnan Cheng, Qiuting Deng, Xiao Zhang, Guangyao Lai, Haitao Nan, Baihua Wu, Xinyi Shentu, Liang Wu, Xiaoyu Wei, Yujia Jiang, Xin Huang, Fengyu Pan, Yumo Song, Ronghai Li, Zhifeng Wang, Chuanyu Liu, Shi-Ping Liu, Yuxiang Li, Tao Yang, Zhicheng Xu, Wensi Du, Ling Li, Tanveer Ahmed, Kai You, Zhen Dai, Li Li, Baoming Qin, Yin-Xiong Li, Liangxue Lai, Dajiang Qin, Junling Chen, Rong Fan, Yongyin Li, Jin-Lin Hou, Michael Ott, Amar Deep Sharma, Tobias Cantz, Axel Schambach, Karsten Kristiansen, Andrew P Hutchins, Berthold Göttgens, Patrick H Maxwell, Lijian Hui, Xue Liu, Longqi Liu, Ao Chen, Yiwei Lai, Miguel Angel Esteban
A spatiotemporal atlas of mouse liver homeostasis and regeneration. Nature genetics (2024)
Xinyu Wu, Ruonan Liu, Zhongtian Zhang, Jie Yang, Xin Liu, Liqiang Jiang, Mengmeng Fang, Shoutang Wang, Liangxue Lai, Yuning Song, Zhanjun Li
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis. EMBO molecular medicine (2024)
Jinze Li, Ding Zhao, Tao Zhang, Haoyang Xiong, Mingyang Hu, Hongmei Liu, Feiyu Zhao, Xiaodi Sun, Peng Fan, Yuqiang Qian, Di Wang, Liangxue Lai, Tingting Sui, Zhanjun Li
Precise large-fragment deletions in mammalian cells and mice generated by dCas9-controlled CRISPR/Cas3. Science advances 10 (11) (2024)
Tao Zhang, Feiyu Zhao, Jinze Li, Xiaodi Sun, Xiyun Zhang, Hejun Wang, Peng Fan, Liangxue Lai, Hongmei Liu, Tingting Sui
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase. Nucleic acids research (2024)
Degong Ruan, Yiyi Xuan, Timothy Theodore Ka Ki Tam, ZhuoXuan Li, Xiao Wang, Shao Xu, Doris Herrmann, Heiner Niemann, Liangxue Lai, Xuefei Gao, Monika Nowak-Imialek, Pengtao Liu
An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells. Nature protocols 19 (6) (2024)
Tao Zhang, Feiyu Zhao, Jinze Li, Xiaodi Sun, Xiyun Zhang, Hejun Wang, Peng Fan, Liangxue Lai, Hongmei Liu, Tingting Sui
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase. Nucleic acids research 52 (6) (2024)
Jiangshan Xu, Pengcheng Guo, Shijie Hao, Shuncheng Shangguan, Quan Shi, Giacomo Volpe, Keke Huang, Jing Zuo, Juan An, Yue Yuan, Mengnan Cheng, Qiuting Deng, Xiao Zhang, Guangyao Lai, Haitao Nan, Baihua Wu, Xinyi Shentu, Liang Wu, Xiaoyu Wei, Yujia Jiang, Xin Huang, Fengyu Pan, Yumo Song, Ronghai Li, Zhifeng Wang, Chuanyu Liu, Shi-Ping Liu, Yuxiang Li, Tao Yang, Zhicheng Xu, Wensi Du, Ling Li, Tanveer Ahmed, Kai You, Zhen Dai, Li Li, Baoming Qin, Yin-Xiong Li, Liangxue Lai, Dajiang Qin, Junling Chen, Rong Fan, Yongyin Li, Jin-Lin Hou, Michael Ott, Amar Deep Sharma, Tobias Cantz, Axel Schambach, Karsten Kristiansen, Andrew P Hutchins, Berthold Göttgens, Patrick H Maxwell, Lijian Hui, Xue Liu, Longqi Liu, Ao Chen, Yiwei Lai, Miguel Angel Esteban
A spatiotemporal atlas of mouse liver homeostasis and regeneration. Nature genetics 56 (5) (2024)
Jiangshan Xu, Pengcheng Guo, Shijie Hao, Shuncheng Shangguan, Quan Shi, Giacomo Volpe, Keke Huang, Jing Zuo, Juan An, Yue Yuan, Mengnan Cheng, Qiuting Deng, Xiao Zhang, Guangyao Lai, Haitao Nan, Baihua Wu, Xinyi Shentu, Liang Wu, Xiaoyu Wei, Yujia Jiang, Xin Huang, Fengyu Pan, Yumo Song, Ronghai Li, Zhifeng Wang, Chuanyu Liu, Shi-Ping Liu, Yuxiang Li, Tao Yang, Zhicheng Xu, Wensi Du, Ling Li, Tanveer Ahmed, Kai You, Zhen Dai, Li Li, Baoming Qin, Yin-Xiong Li, Liangxue Lai, Dajiang Qin, Junling Chen, Rong Fan, Yongyin Li, Jin-Lin Hou, Michael Ott, Amar Deep Sharma, Tobias Cantz, Axel Schambach, Karsten Kristiansen, Andrew P Hutchins, Berthold Göttgens, Patrick H Maxwell, Lijian Hui, Xue Liu, Longqi Liu, Ao Chen, Yiwei Lai, Miguel Angel Esteban
A spatiotemporal atlas of mouse liver homeostasis and regeneration. Nature genetics (2024)
Jinze Li, Ding Zhao, Tao Zhang, Haoyang Xiong, Mingyang Hu, Hongmei Liu, Feiyu Zhao, Xiaodi Sun, Peng Fan, Yuqiang Qian, Di Wang, Liangxue Lai, Tingting Sui, Zhanjun Li
Precise large-fragment deletions in mammalian cells and mice generated by dCas9-controlled CRISPR/Cas3. Science advances 10 (11) (2024)
Tao Zhang, Feiyu Zhao, Jinze Li, Xiaodi Sun, Xiyun Zhang, Hejun Wang, Peng Fan, Liangxue Lai, Hongmei Liu, Tingting Sui
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase. Nucleic acids research 52 (6) (2024)
Tao Zhang, Feiyu Zhao, Jinze Li, Xiaodi Sun, Xiyun Zhang, Hejun Wang, Peng Fan, Liangxue Lai, Hongmei Liu, Tingting Sui
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase. Nucleic acids research 52 (6) (2024)
Jingke Xie, Zhenpeng Zhuang, Shixue Gou, Quanjun Zhang, Xia Wang, Ting Lan, Meng Lian, Nan Li, Yanhui Liang, Zhen Ouyang, Yinghua Ye, Han Wu, Liangxue Lai, Kepin Wang
Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription. Nucleic acids research (2023)
Tao Chen, Chengcheng Tang, Wei Zheng, Yanan Qian, Min Chen, Qingjian Zou, Yinge Jin, Kepin Wang, Xiaoqing Zhou, Shixue Gou, Liangxue Lai
VCFshiny: an R/Shiny application for interactively analyzing and visualizing genetic variants. Bioinformatics advances 3 (1) (2023)
Sen Yan, Xiao Zheng, Yingqi Lin, Caijuan Li, Zhaoming Liu, Jiawei Li, Zhuchi Tu, Yu Zhao, Chunhui Huang, Yizhi Chen, Jun Li, Xichen Song, Bofeng Han, Wei Wang, Weien Liang, Liangxue Lai, Xiao-Jiang Li, Xiao-Jiang Li
Cas9-mediated replacement of expanded CAG repeats in a pig model of Huntington's disease. Nature biomedical engineering (2023)
Feiyu Zhao, Tao Zhang, Xiaodi Sun, Xiyun Zhang, Letong Chen, Hejun Wang, Jinze Li, Peng Fan, Liangxue Lai, Tingting Sui, Zhanjun Li
A strategy for Cas13 miniaturization based on the structure and AlphaFold. Nature communications 14 (1) (2023)
Zhiquan Liu, Siyu Chen, Wanhua Xie, Hao Yu, Liangxue Lai, Zhanjun Li
Versatile and efficient genome editing with Neisseria cinerea Cas9. Communications biology 5 (1) (2022)
Shuwen Zheng, Haiwen Zhong, Xiaoqing Zhou, Min Chen, Wansheng Li, Yin Zi, Yue Chi, Jinling Wang, Wei Zheng, Qingjian Zou, Liangxue Lai, Chengcheng Tang
Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor. Cells 11 (24) (2022)
Shuwen Zheng, Haiwen Zhong, Xiaoqing Zhou, Min Chen, Wansheng Li, Yin Zi, Yue Chi, Jinling Wang, Wei Zheng, Qingjian Zou, Liangxue Lai, Chengcheng Tang
Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor. Cells 11 (24) (2022)
Yingqi Jia, Tian Wang, Ding Zhao, Zhiquan Liu, Tingting Sui, Siyu Chen, Jinze Li, Liangxue Lai, Zhanjun Li
Targeted mutagenesis in rabbit using an engineered BhCas12b variant. Journal of molecular cell biology (2022)
Shuwen Zheng, Haiwen Zhong, Xiaoqing Zhou, Min Chen, Wansheng Li, Yin Zi, Yue Chi, Jinling Wang, Wei Zheng, Qingjian Zou, Liangxue Lai, Chengcheng Tang
Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor. Cells 11 (24) (2022)
Yanhui Liang, Jingke Xie, Quanjun Zhang, Xiaomin Wang, Shixue Gou, Lihui Lin, Tao Chen, Weikai Ge, Zhenpeng Zhuang, Meng Lian, Fangbing Chen, Nan Li, Zhen Ouyang, Chengdan Lai, Xiaoyi Liu, Lei Li, Yinghua Ye, Han Wu, Kepin Wang, Liangxue Lai
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns. Nucleic acids research 50 (9) (2022)
Fangbing Chen, Meng Lian, Bingxiu Ma, Shixue Gou, Xian Luo, Kaiming Yang, Hui Shi, Jingke Xie, Weika Ge, Zhen Ouyang, Chengdan Lai, Nan Li, Quanjun Zhang, Qin Jin, Yanhui Liang, Tao Chen, Jiaowei Wang, Xiaozhu Zhao, Lei Li, Manya Yu, Yinghua Ye, Kepin Wang, Han Wu, Liangxue Lai
Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors. Communications biology 5 (1) (2022)
Shuwen Zheng, Haiwen Zhong, Xiaoqing Zhou, Min Chen, Wansheng Li, Yin Zi, Yue Chi, Jinling Wang, Wei Zheng, Qingjian Zou, Liangxue Lai, Chengcheng Tang
Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor. Cells 11 (24) (2022)
Han Wu, Qishuai Liu, Hui Shi, Jingke Xie, Quanjun Zhang, Zhen Ouyang, Nan Li, Yi Yang, Zhaoming Liu, Yu Zhao, Chengdan Lai, Degong Ruan, Jiangyun Peng, Weikai Ge, Fangbing Chen, Nana Fan, Qin Jin, Yanhui Liang, Ting Lan, Xiaoyu Yang, Xiaoshan Wang, Zhiyong Lei, Pieter A Doevendans, Joost P G Sluijter, Kepin Wang, Xiaoping Li, Liangxue Lai
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems. Cellular and molecular life sciences : CMLS 75 (19) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Liangxue Lai