Linda V Sinclair

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 21

Top Topics

Ulcerative Colitis

Emergency Medicine

Plasmodium Falciparum

Top Venues

The Journal of experimental medicine

Journal of immunology (Baltimore, Md. : 1950)

Nature communications

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Eimear K Ryan, Christy H Clutter, Conor De Barra, Benjamin J Jenkins, Simon O'Shaughnessy, Odhrán K Ryan, Chloe McKenna, Helen M Heneghan, Fiona Walsh, David K Finlay, Linda V Sinclair, Nicholas Jones, Daniel T Leung, Donal O'Shea, Andrew E Hogan
Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions. Journal of immunology (Baltimore, Md. : 1950) (2024)
Eimear K Ryan, Christy H Clutter, Conor De Barra, Benjamin J Jenkins, Simon O'Shaughnessy, Odhrán K Ryan, Chloe McKenna, Helen M Heneghan, Fiona Walsh, David K Finlay, Linda V Sinclair, Nicholas Jones, Daniel T Leung, Donal O'Shea, Andrew E Hogan
Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions. Journal of immunology (Baltimore, Md. : 1950) (2024)
Eimear K Ryan, Christy H Clutter, Conor De Barra, Benjamin J Jenkins, Simon O'Shaughnessy, Odhrán K Ryan, Chloe McKenna, Helen M Heneghan, Fiona Walsh, David K Finlay, Linda V Sinclair, Nicholas Jones, Daniel T Leung, Donal O'Shea, Andrew E Hogan
Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions. Journal of immunology (Baltimore, Md. : 1950) 212 (11) (2024)
Eimear K Ryan, Christy H Clutter, Conor De Barra, Benjamin J Jenkins, Simon O'Shaughnessy, Odhrán K Ryan, Chloe McKenna, Helen M Heneghan, Fiona Walsh, David K Finlay, Linda V Sinclair, Nicholas Jones, Daniel T Leung, Donal O'Shea, Andrew E Hogan
Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions. Journal of immunology (Baltimore, Md. : 1950) (2024)
Nidhi Kedia-Mehta, Marta M Pisarska, Christina Rollings, Chloe A O'Neill, Conor De Barra, Cathriona Foley, Nicole A W Wood, Neil Wrigley-Kelly, Natacha Veerapen, Gurdyal S Besra, Ronan Bergin, Nicholas Jones, Donal O'Shea, Linda V Sinclair, Andrew E Hogan
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis. Science signaling 16 (781) (2023)
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden, Gordana Panic, Richard K Grencis, Jonathan R Swann, Linda V Sinclair, Matthew R Hepworth
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses. The Journal of experimental medicine 220 (3) (2022)
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden, Gordana Panic, Richard K Grencis, Jonathan R Swann, Linda V Sinclair, Matthew R Hepworth
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses. The Journal of experimental medicine 220 (3) (2022)
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden, Gordana Panic, Richard K Grencis, Jonathan R Swann, Linda V Sinclair, Matthew R Hepworth
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses. The Journal of experimental medicine 220 (3) (2022)
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden, Gordana Panic, Richard K Grencis, Jonathan R Swann, Linda V Sinclair, Matthew R Hepworth
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses. The Journal of experimental medicine 220 (3) (2022)
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden, Gordana Panic, Richard K Grencis, Jonathan R Swann, Linda V Sinclair, Matthew R Hepworth
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses. The Journal of experimental medicine 220 (3) (2022)
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden, Gordana Panic, Richard K Grencis, Jonathan R Swann, Linda V Sinclair, Matthew R Hepworth
Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses. The Journal of experimental medicine 220 (3) (2022)
Laura J Pallett, Sarah Dimeloe, Linda V Sinclair, Adam J Byrne, Anna Schurich
A glutamine 'tug-of-war': targets to manipulate glutamine metabolism for cancer immunotherapy. Immunotherapy advances 1 (1) (2021)
Julia M Marchingo, Linda V Sinclair, Andrew J M Howden, Doreen A Cantrell
Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation. eLife 9 (2020)
Ana Villegas-Mendez, Garima Khandelwal, Lucy M McGowan, Rebecca S Dookie, Michael J Haley, Charlotte George, David Sims, Graham M Lord, Linda V Sinclair, Richard G Jenner, Kevin N Couper
Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression. Journal of immunology (Baltimore, Md. : 1950) 205 (6) (2020)
Andrew J M Howden, Jens L Hukelmann, Alejandro Brenes, Laura Spinelli, Linda V Sinclair, Angus I Lamond, Doreen A Cantrell
Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation. Nature immunology 20 (11) (2019)
Aisling O'Brien, Roisín M Loftus, Marta M Pisarska, Laura M Tobin, Ronan Bergin, Nicole A W Wood, Cathriona Foley, Arimin Mat, Frances C Tinley, Ciaran Bannan, Gary Sommerville, Natacha Veerapen, Gurdyal S Besra, Linda V Sinclair, Paul N Moynagh, Lydia Lynch, David K Finlay, Donal O'Shea, Andrew E Hogan
Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses. Journal of immunology (Baltimore, Md. : 1950) 202 (12) (2019)
Linda V Sinclair, Andrew J M Howden, Alejandro J Brenes, Laura Spinelli, Jens L Hukelmann, Andrew N Macintyre, Xiaojing Liu, Sarah Thomson, Peter M Taylor, Jeffrey C Rathmell, Jason W Locasale, Angus I Lamond, Doreen A Cantrell
Antigen receptor control of methionine metabolism in T cells. eLife 8 (2019)
Christina M Rollings, Linda V Sinclair, Hugh J M Brady, Doreen A Cantrell, Sarah H Ross
Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs. Science signaling 11 (526) (2018)
Róisín M Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie L O'Brien, Arianne Garcia, Conor Gillespie, Jens L Hukelmann, Peter J Oefner, Angus I Lamond, Clair M Gardiner, Katja Dettmer, Doreen A Cantrell, Linda V Sinclair, David K Finlay
Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice. Nature communications 9 (1) (2018)
Linda V Sinclair, Damien Neyens, George Ramsay, Peter M Taylor, Doreen A Cantrell
Single cell analysis of kynurenine and System L amino acid transport in T cells. Nature communications 9 (1) (2018)
Simon J Lawless, Nidhi Kedia-Mehta, Jessica F Walls, Ryan McGarrigle, Orla Convery, Linda V Sinclair, Maria N Navarro, James Murray, David K Finlay
Glucose represses dendritic cell-induced T cell responses. Nature communications 8 (2017)