Gurdyal S Besra (Gurdyal Besra)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 53

Top Venues

Nature communications

Nature microbiology

Scientific reports

The Journal of experimental medicine

University of Birmingham

Newcastle upon Tyne (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Birmingham

United Kingdom

Bardrick Professor of Microbial Physiology & Chemistry :: School of Biosciences

University of Newcastle upon Tyne

United Kingdom

Professor of Microbial Physiology :: Department of Microbiology & Immunology

University of Newcastle upon Tyne

United Kingdom

Lister Institute-Jenner Research Fellow :: Department of Microbiology & Immunology

University of Newcastle upon Tyne

United States

Reader :: Department of Microbiology & Immunology

Colorado State University

United States

Assistant Professor :: Department of Microbiology

Colorado State University

United States

Senior Research Scientist :: Department of Microbiology

Colorado State University

United States

Research Scientist :: Department of Microbiology

Colorado State University

United States

Postdoctoral Fellow :: Department of Microbiology

Education History

Newcastle upon Tyne

United Kingdom

PHD

Newcastle upon Tyne

United Kingdom

BSC

Publications

Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nature microbiology 9 (4) (2024)
Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nature microbiology 9 (4) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nature microbiology 9 (4) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nature microbiology (2024)
Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nature microbiology 9 (4) (2024)
Aaron Franklin, Vivian C Salgueiro, Abigail J Layton, Rudi Sullivan, Todd Mize, Lucía Vázquez-Iniesta, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Rafael Prados-Rosales, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. Nature communications 15 (1) (2024)
Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis. Nature microbiology 9 (4) (2024)
Andrew Chancellor, Robert Alan Simmons, Rahul C Khanolkar, Vladimir Nosi, Aisha Beshirova, Giuliano Berloffa, Rodrigo Colombo, Vijaykumar Karuppiah, Johanne M Pentier, Vanessa M Tubb, Hemza Ghadbane, Richard J Suckling, Keith Page, Rory M Crean, Alessandro Vacchini, Corinne De Gregorio, Verena Schaefer, Daniel Constantin, Thomas Gligoris, Angharad Lloyd, Miriam Hock, Velupillai Srikannathasan, Ross A Robinson, Gurdyal S Besra, Marc W Van der Kamp, Lucia Mori, Raffaele Adolfo Calogero, David K Cole, Gennaro De Libero, Marco Lepore
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. The Journal of experimental medicine 220 (9) (2023)
Andrew Chancellor, Robert Alan Simmons, Rahul C Khanolkar, Vladimir Nosi, Aisha Beshirova, Giuliano Berloffa, Rodrigo Colombo, Vijaykumar Karuppiah, Johanne M Pentier, Vanessa M Tubb, Hemza Ghadbane, Richard J Suckling, Keith Page, Rory M Crean, Alessandro Vacchini, Corinne De Gregorio, Verena Schaefer, Daniel Constantin, Thomas Gligoris, Angharad Lloyd, Miriam Hock, Velupillai Srikannathasan, Ross A Robinson, Gurdyal S Besra, Marc W Van der Kamp, Lucia Mori, Raffaele Adolfo Calogero, David K Cole, Gennaro De Libero, Marco Lepore
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. The Journal of experimental medicine 220 (9) (2023)
Nidhi Kedia-Mehta, Marta M Pisarska, Christina Rollings, Chloe A O'Neill, Conor De Barra, Cathriona Foley, Nicole A W Wood, Neil Wrigley-Kelly, Natacha Veerapen, Gurdyal S Besra, Ronan Bergin, Nicholas Jones, Donal O'Shea, Linda V Sinclair, Andrew E Hogan
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis. Science signaling 16 (781) (2023)
Katherine A Abrahams, Sarah M Batt, Sudagar S Gurcha, Natacha Veerapen, Ghader Bashiri, Gurdyal S Besra
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid. Nature communications 14 (1) (2023)
Katherine A Abrahams, Sarah M Batt, Sudagar S Gurcha, Natacha Veerapen, Ghader Bashiri, Gurdyal S Besra
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid. Nature communications 14 (1) (2023)
Katherine A Abrahams, Sarah M Batt, Sudagar S Gurcha, Natacha Veerapen, Ghader Bashiri, Gurdyal S Besra
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid. Nature communications 14 (1) (2023)
Katherine A Abrahams, Sarah M Batt, Sudagar S Gurcha, Natacha Veerapen, Ghader Bashiri, Gurdyal S Besra
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid. Nature communications 14 (1) (2023)
Katherine A Abrahams, Sarah M Batt, Sudagar S Gurcha, Natacha Veerapen, Ghader Bashiri, Gurdyal S Besra
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid. Nature communications 14 (1) (2023)
Andrew Chancellor, Robert Alan Simmons, Rahul C Khanolkar, Vladimir Nosi, Aisha Beshirova, Giuliano Berloffa, Rodrigo Colombo, Vijaykumar Karuppiah, Johanne M Pentier, Vanessa M Tubb, Hemza Ghadbane, Richard J Suckling, Keith Page, Rory M Crean, Alessandro Vacchini, Corinne De Gregorio, Verena Schaefer, Daniel Constantin, Thomas Gligoris, Angharad Lloyd, Miriam Hock, Velupillai Srikannathasan, Ross A Robinson, Gurdyal S Besra, Marc W Van der Kamp, Lucia Mori, Raffaele Adolfo Calogero, David K Cole, Gennaro De Libero, Marco Lepore
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. The Journal of experimental medicine 220 (9) (2023)
Yicheng Gong, Chuancun Wei, Jun Wang, Nengjiang Mu, Qinhong Lu, Chengyao Wu, Ning Yan, Huifang Yang, Yao Zhao, Xiu-Na Yang, Sudagar S Gurcha, Natacha Veerapen, Sarah M Batt, Zhiqiang Hao, Lintai Da, Gurdyal S Besra, Zihe Rao, Lu Zhang
Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis . Proceedings of the National Academy of Sciences of the United States of America 120 (23) (2023)
Aaron Franklin, Abigail J Layton, Todd Mize, Vivian C Salgueiro, Rudi Sullivan, Samuel T Benedict, Sudagar S Gurcha, Itxaso Anso, Gurdyal S Besra, Manuel Banzhaf, Andrew Lee Lovering, Spencer J Williams, Marcelo E Guerin, Nichollas E Scott, Vivian C Salgueiro, Elisabeth C Lowe, Patrick Joseph Moynihan
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth. bioRxiv : the preprint server for biology (2023)
Andrew Chancellor, Robert Alan Simmons, Rahul C Khanolkar, Vladimir Nosi, Aisha Beshirova, Giuliano Berloffa, Rodrigo Colombo, Vijaykumar Karuppiah, Johanne M Pentier, Vanessa M Tubb, Hemza Ghadbane, Richard J Suckling, Keith Page, Rory M Crean, Alessandro Vacchini, Corinne De Gregorio, Verena Schaefer, Daniel Constantin, Thomas Gligoris, Angharad Lloyd, Miriam Hock, Velupillai Srikannathasan, Ross A Robinson, Gurdyal S Besra, Marc W Van der Kamp, Lucia Mori, Raffaele Adolfo Calogero, David K Cole, Gennaro De Libero, Marco Lepore
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses. The Journal of experimental medicine 220 (9) (2023)
Marion Pouget, Anna K Coussens, Alessandra Ruggiero, Anastasia Koch, Jordan Thomas, Gurdyal S Besra, Robert John Wilkinson, Apoorva Bhatt, Georgios Pollakis, William A Paxton
Generation of Liposomes to Study the Effect of Mycobacterium Tuberculosis Lipids on HIV-1 cis- and trans-Infections. International journal of molecular sciences 22 (4) (2021)
Pengxu Wang, Sarah M Batt, Bin Wang, Lei Fu, Rongfei Qin, Yu Lu, Gang Li, Gurdyal S Besra, Haihong Huang
Discovery of Novel Thiophene-arylamide Derivatives as DprE1 Inhibitors with Potent Antimycobacterial Activities. Journal of medicinal chemistry 64 (9) (2021)
Rachel N Cotton, Marcin Wegrecki, Tan-Yun Cheng, Yi-Ling Chen, Natacha Veerapen, Jérôme Le Nours, Dennis P Orgill, Bohdan Pomahac, Simon G Talbot, Richard A Willis, John D Altman, Annemieke de Jong, Ildiko Van Rhijn, Rachael A Clark, Gurdyal S Besra, Graham S Ogg, Jamie Rossjohn, D Branch Moody
CD1a selectively captures endogenous cellular lipids that broadly block T cell response. The Journal of experimental medicine 218 (7) (2021)
Katherine A Abrahams, Gurdyal S Besra
Mycobacterial drug discovery. RSC medicinal chemistry 11 (12) (2020)
Shipra Grover, Curtis A Engelhart, Esther Pérez-Herrán, Wei Li, Katherine A Abrahams, Kadamba Papavinasasundaram, James M Bean, Christopher M Sassetti, Alfonso Mendoza-Losana, Gurdyal S Besra, Mary Jackson, Dirk Schnappinger
Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis. ACS infectious diseases 7 (1) (2020)
Lorena Preciado-Llanes, Anna Aulicino, Rocío Canals, Patrick Joseph Moynihan, Xiaojun Zhu, Ndaru Jambo, Tonney S Nyirenda, Innocent Kadwala, Ana Sousa Gerós, Siân V Owen, Kondwani C Jambo, Benjamin Kumwenda, Natacha Veerapen, Gurdyal S Besra, Melita A Gordon, Jay C D Hinton, Giorgio Napolitani, Mariolina Salio, Alison Simmons
Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease. Proceedings of the National Academy of Sciences of the United States of America 117 (34) (2020)
Lu Zhang, Yao Zhao, Yan Gao, Li-Jie Wu, Ruogu Gao, Qi Zhang, Yinan Wang, Chengyao Wu, Fangyu Wu, Sudagar S Gurcha, Natacha Veerapen, Sarah M Batt, Wei Zhao, Ling Qin, Xiuna Yang, Manfu Wang, Yan Zhu, Bing Zhang, Lijun Bi, Xian'en Zhang, Haitao Yang, Luke W Guddat, Wenqing Xu, Quan Wang, Jun Li, Gurdyal S Besra, Zihe Rao
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science (New York, N.Y.) 368 (6496) (2020)
Aisling O' Brien, Nidhi Kedia-Mehta, Laura Tobin, Natacha Veerapen, Gurdyal S Besra, Donal O' Shea, Andrew E Hogan
Targeting mitochondrial dysfunction in MAIT cells limits IL-17 production in obesity. Cellular & molecular immunology 17 (11) (2020)
Patrick Joseph Moynihan, Ian T Cadby, Natacha Veerapen, Monika Jankute, Marialuisa Crosatti, Galina V Mukamolova, Andrew L Lovering, Gurdyal S Besra
The hydrolase LpqI primes mycobacterial peptidoglycan recycling. Nature communications 10 (1) (2019)
Aisling O'Brien, Roisín M Loftus, Marta M Pisarska, Laura M Tobin, Ronan Bergin, Nicole A W Wood, Cathriona Foley, Arimin Mat, Frances C Tinley, Ciaran Bannan, Gary Sommerville, Natacha Veerapen, Gurdyal S Besra, Linda V Sinclair, Paul N Moynagh, Lydia Lynch, David K Finlay, Donal O'Shea, Andrew E Hogan
Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses. Journal of immunology (Baltimore, Md. : 1950) 202 (12) (2019)
Adrian Richter, Ines Rudolph, Ute Möllmann, Kerstin Voigt, Chun-Wa Chung, Onkar M P Singh, Michael Rees, Alfonso Mendoza-Losana, Robert Bates, Lluís Ballell, Sarah Batt, Natacha Veerapen, Klaus Fütterer, Gurdyal S Besra, Peter Imming, Argyrides Argyrou
Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. Scientific reports 8 (1) (2018)
Lauren J Howson, Giorgio Napolitani, Dawn Shepherd, Hemza Ghadbane, Prathiba Kurupati, Lorena Preciado-Llanes, Margarida Rei, Hazel C Dobinson, Malick M Gibani, Karen Wei Weng Teng, Evan William Newell, Natacha Veerapen, Gurdyal S Besra, Andrew J Pollard, Vincenzo Cerundolo
MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A. Nature communications 9 (1) (2018)
Natacha Veerapen, Shalu Sharma Kharkwal, Peter Jervis, Veemal Bhowruth, Amareeta K Besra, Simon J North, Stuart M Haslam, Anne Dell, Judith Hobrath, Padraic J Quaid, Patrick J Moynihan, Liam R Cox, Himanshu Kharkwal, Maurice Zauderer, Gurdyal S Besra, Steven A Porcelli
Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation. Bioconjugate chemistry 29 (9) (2018)
Ramón Soto, Esther Perez-Herran, Beatriz Rodriguez, Bogdan M Duma, Monica Cacho-Izquierdo, Alfonso Mendoza-Losana, Joel Lelievre, David Barros Aguirre, Lluis Ballell, Liam R Cox, Luke J Alderwick, Gurdyal S Besra
Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach. Scientific reports 8 (1) (2018)
Alexiane Decout, Sandro Silva-Gomes, Daniel Drocourt, Emilyne Blattes, Michel Rivière, Jacques Prandi, Gérald Larrouy-Maumus, Anne-Marie Caminade, Beston Hamasur, Gunilla Källenius, Devinder Kaur, Karen M Dobos, Megan Lucas, Iain C Sutcliffe, Gurdyal S Besra, Ben J Appelmelk, Martine Gilleron, Mary Jackson, Alain Vercellone, Gérard Tiraby, Jérôme Nigou
Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2. Scientific reports 8 (1) (2018)
Valentin Trofimov, Sébastien Kicka, Sabrina Mucaria, Nabil Hanna, Fernando Ramon-Olayo, Laura Vela-Gonzalez Del Peral, Joël Lelièvre, Lluís Ballell, Leonardo Scapozza, Gurdyal S Besra, Jonathan A G Cox, Thierry Soldati
Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets. Scientific reports 8 (1) (2018)
Shilpi Chandra, James Gray, William B Kiosses, Archana Khurana, Kaori Hitomi, Catherine M Crosby, Ashu Chawla, Zheng Fu, Meng Zhao, Natacha Veerapen, Stewart K Richardson, Steven A Porcelli, Gurdyal S Besra, Amy R Howell, Sonia Sharma, Bjoern Peters, Mitchell Kronenberg
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nature communications 9 (1) (2018)
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan, Jianzhong Huang, Lluis Ballell, Svetlana Belyanskaya, Gurdyal S Besra, David Barros-Aguirre, Robert H Bates, Paolo A Centrella, Sandy S Chang, Jing Chai, Anthony E Choudhry, Aaron Coffin, Christopher P Davie, Hongfeng Deng, Jianghe Deng, Yun Ding, Jason W Dodson, David T Fosbenner, Enoch N Gao, Taylor L Graham, Todd L Graybill, Karen Ingraham, Walter P Johnson, Bryan W King, Christopher R Kwiatkowski, Joël Lelièvre, Yue Li, Xiaorong Liu, Quinn Lu, Ruth Lehr, Alfonso Mendoza-Losana, John Martin, Lynn McCloskey, Patti McCormick, Heather P O'Keefe, Thomas O'Keeffe, Christina Pao, Christopher B Phelps, Hongwei Qi, Keith Rafferty, Genaro S Scavello, Matt S Steiginga, Flora S Sundersingh, Sharon M Sweitzer, Lawrence M Szewczuk, Amy Taylor, May Fern Toh, Juan Wang, Minghui Wang, Devan J Wilkins, Bing Xia, Gang Yao, Jean Zhang, Jingye Zhou, Christine P Donahue, Jeffrey A Messer, David Holmes, Christopher C Arico-Muendel, Andrew J Pope, Jeffrey W Gross, Ghotas Evindar
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening. Nature communications 8 (2017)
Monika Jankute, Vijayashankar Nataraj, Oona Y-C Lee, Houdini H T Wu, Malin Ridell, Natalie J Garton, Michael R Barer, David E Minnikin, Apoorva Bhatt, Gurdyal S Besra
The role of hydrophobicity in tuberculosis evolution and pathogenicity. Scientific reports 7 (1) (2017)
Katherine A Abrahams, Jonathan A G Cox, Klaus Fütterer, Joaquín Rullas, Fátima Ortega-Muro, Nicholas J Loman, Patrick J Moynihan, Esther Pérez-Herrán, Elena Jiménez, Jorge Esquivias, David Barros, Lluís Ballell, Carlos Alemparte, Gurdyal S Besra
Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface. Scientific reports 7 (1) (2017)
Rebecca Newman, Helena Ahlfors, Alexander Saveliev, Alison Galloway, Daniel J Hodson, Robert Williams, Gurdyal S Besra, Charlotte N Cook, Adam F Cunningham, Sarah E Bell, Martin Turner
Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1. Nature immunology 18 (6) (2017)
Mariolina Salio, Olivier Gasser, Claudia Gonzalez-Lopez, Anne Martens, Natacha Veerapen, Uzi Gileadi, Jacob G Verter, Giorgio Napolitani, Regan J Anderson, Gavin A Painter, Gurdyal S Besra, Ian F Hermans, Vincenzo Cerundolo
Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells. Journal of immunology (Baltimore, Md. : 1950) 199 (8) (2017)
Monika Jankute, Luke J Alderwick, Stephan Noack, Natacha Veerapen, Jérôme Nigou, Gurdyal S Besra
Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan. ACS chemical biology 12 (1) (2016)
Jonathan A G Cox, Katherine A Abrahams, Carlos Alemparte, Sonja Ghidelli-Disse, Joaquín Rullas, Iñigo Angulo-Barturen, Albel Singh, Sudagar S Gurcha, Vijayashankar Nataraj, Stephen Bethell, Modesto J Remuiñán, Lourdes Encinas, Peter J Jervis, Nicholas C Cammack, Apoorva Bhatt, Ulrich Kruse, Marcus Bantscheff, Klaus Fütterer, David Barros, Lluis Ballell, Gerard Drewes, Gurdyal S Besra
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nature microbiology 1 (2016)
Jérôme Le Nours, T Praveena, Daniel G Pellicci, Nicholas A Gherardin, Fiona J Ross, Ricky T Lim, Gurdyal S Besra, Santosh Keshipeddy, Stewart K Richardson, Amy R Howell, Stephanie Gras, Dale I Godfrey, Jamie Rossjohn, Adam P Uldrich
Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nature communications 7 (2016)

Gurdyal S Besra.css-eqlu8i{font-size:small;padding-left:4px;} (Gurdyal Besra)

Publication Activity (10 Years)

Top Topics

Top Venues

Gurdyal S Besra (Gurdyal Besra)