Lukas A Huber

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 31

Top Venues

Nature

eLife

Nature communications

Traffic (Copenhagen, Denmark)

ADSI, Austrian Drug Screening Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

ADSI, Austrian Drug Screening Institute

Austria

Director

Oncotyrol, Centre for Personalized Cancer Medicine

Austria

CSO

Medical University Innsbruck

Austria

Director Cell Biology :: Biocenter

University of Innsbruck

Austria

Cairman and Full professor :: Histology and Molecular Cell Biology

Institute of Molecular Pathology, IMP

Austria

Group Leader

Université de Genève, Sciences II

Switzerland

Maître Assistant :: Département de Biochimie

European Molecular Biology Laboratory (EMBL),

Germany

PostDoc :: Cell Biology

University of Innsbruck

Austria

Thesis "Immunology of Ageing: Immuno regulatory Properties of Lipoproteins". :: Institute for General and Experimental Pathology

Publications

Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature 614 (7948) (2023)
Katharina M C Klee, Michael W Hess, Michael Lohmüller, Sebastian Herzog, Kristian Pfaller, Thomas Müller, Georg-Friedrich Vogel, Lukas A Huber
A CRISPR screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. eLife 12 (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature (2023)
Irene Sambri, Marco Ferniani, Giulia Campostrini, Marialuisa Testa, Viviana Meraviglia, Mariana E G de Araujo, Ladislav Dokládal, Claudia Vilardo, Jlenia Monfregola, Nicolina Zampelli, Francesca Del Vecchio Blanco, Annalaura Torella, Carolina Ruosi, Simona Fecarotta, Giancarlo Parenti, Leopoldo Staiano, Milena Bellin, Lukas A Huber, Claudio De Virgilio, Francesco Trepiccione, Vincenzo Nigro, Andrea Balabio
RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome. Nature communications 14 (1) (2023)
Katharina M C Klee, Michael W Hess, Michael Lohmüller, Sebastian Herzog, Kristian Pfaller, Thomas Müller, Georg-Friedrich Vogel, Lukas A Huber
A CRISPR screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. eLife 12 (2023)
Katharina M C Klee, Michael W Hess, Michael Lohmüller, Sebastian Herzog, Kristian Pfaller, Thomas Müller, Georg-Friedrich Vogel, Lukas A Huber
A CRISPR screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. eLife 12 (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature 614 (7948) (2023)
Katharina M C Klee, Michael W Hess, Michael Lohmüller, Sebastian Herzog, Kristian Pfaller, Thomas Müller, Georg-Friedrich Vogel, Lukas A Huber
A CRISPR screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. eLife 12 (2023)
Can Gollmann-Tepeköylü, Michael Graber, Jakob Hirsch, Sophia Mair, Andreas Naschberger, Leo Pölzl, Felix Nägele, Elke Kirchmair, Gerald Degenhart, Egon Demetz, Richard Hilbe, Hao-Yu Chen, James C Engert, Anna Boehm, Nadja Franz, Daniela Lobenwein, Daniela Lener, Christiane Fuchs, Anna Weihs, Sonja Töchterle, Georg-Friedrich Vogel, Victor Schweiger, Jonas Eder, Peter Pietschmann, Markus Seifert, Florian Kronenberg, Stefan Coassin, Michael Blumer, Hubert Hackl, Dirk Meyer, Gudrun Maria Feuchtner, Rudolf Kirchmair, Jakob Troppmair, Markus Krane, Guenter Weiss, Sotirios Tsimikas, George Thanassoulis, Michael Grimm, Bernhard Rupp, Lukas A Huber, Shen-Ying Zhang, Jean-Laurent Casanova, Ivan Tancevski, Johannes Holfeld
Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification. Circulation (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature 614 (7948) (2023)
Ilja Vietor, Domagoj Cikes, Kati Piironen, Theodora Vasakou, David Heimdörfer, Ronald Gstir, Matthias David Erlacher, Ivan Tancevski, Philipp Eller, Egon Demetz, Michael W Hess, Volker Kuhn, Gerald Degenhart, Jan Rozman, Martin Klingenspor, Martin Hrabě de Angelis, Taras Valovka, Lukas A Huber
The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15). eLife 12 (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature 614 (7948) (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature 614 (7948) (2023)
Irene Sambri, Marco Ferniani, Giulia Campostrini, Marialuisa Testa, Viviana Meraviglia, Mariana E G de Araujo, Ladislav Dokládal, Claudia Vilardo, Jlenia Monfregola, Nicolina Zampelli, Francesca Del Vecchio Blanco, Annalaura Torella, Carolina Ruosi, Simona Fecarotta, Giancarlo Parenti, Leopoldo Staiano, Milena Bellin, Lukas A Huber, Claudio De Virgilio, Francesco Trepiccione, Vincenzo Nigro, Andrea Balabio
RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome. Nature communications 14 (1) (2023)
Irene Sambri, Marco Ferniani, Giulia Campostrini, Marialuisa Testa, Viviana Meraviglia, Mariana E G de Araujo, Ladislav Dokládal, Claudia Vilardo, Jlenia Monfregola, Nicolina Zampelli, Francesca Del Vecchio Blanco, Annalaura Torella, Carolina Ruosi, Simona Fecarotta, Giancarlo Parenti, Leopoldo Staiano, Milena Bellin, Lukas A Huber, Claudio De Virgilio, Francesco Trepiccione, Vincenzo Nigro, Andrea Balabio
RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome. Nature communications 14 (1) (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature (2023)
Katharina M C Klee, Michael W Hess, Michael Lohmüller, Sebastian Herzog, Kristian Pfaller, Thomas Müller, Georg-Friedrich Vogel, Lukas A Huber
A CRISPR-screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. eLife 12 (2023)
Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Balabio, James H Hurley
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature (2023)
Katharina M C Klee, Michael W Hess, Michael Lohmüller, Sebastian Herzog, Kristian Pfaller, Thomas Müller, Georg-Friedrich Vogel, Lukas A Huber
A CRISPR-screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. eLife 12 (2023)
Ferda Ö Hoşnut, Andreas R Janecke, Gülseren Şahin, Georg-Friedrich Vogel, Naz Guleray Lafcı, Paul Bichler, Rupert Oberhuber, Lukas A Huber, Taras Valovka, Aysel Ü Aksu
SLC5A1 Variants in Turkish Patients with Congenital Glucose-Galactose Malabsorption. Genes 14 (7) (2023)
Peter D Leitner, Thomas Jakschitz, Ronald Gstir, Stefan Stuppner, Sebastian Perkams, Maren Kruus, Alexander Trockenbacher, Christoph Griesbeck, Günther K Bonn, Lukas A Huber, Taras Valovka
Anti-Inflammatory Extract from Soil Algae Chromochloris zofingiensis Targeting TNFR/NF-κB Signaling at Different Levels. Cells 11 (9) (2022)
Andreas R Janecke, Xiaoqin Liu, Rüdiger Adam, Sumanth Punuru, Arne Viestenz, Valeria Strauß, Martin Laass, Elizabeth Sanchez, Roberto Adachi, Martha P Schatz, Ujwala S Saboo, Naveen Mittal, Klaus Rohrschneider, Johanna C Escher, Anuradha Ganesh, Sana Al Zuhaibi, Fathiya Al Murshedi, Badr M Rasheed Alsaleem, Majid Alfadhel, Siham Al Sinani, Fowzan Sami Alkuraya, Lukas A Huber, Thomas Müller, Ruth Heidelberger, Roger Janz
Pathogenic STX3 variants affecting the retinal and intestinal transcripts cause an early-onset severe retinal dystrophy in microvillus inclusion disease subjects. Human genetics 140 (8) (2021)
Viktoria Zaderer, Wilfried Posch, Ronald Gstir, Przemyslaw A Filipek, Günther K Bonn, Pornanong Aramwit, Lukas A Huber, Doris Wilflingseder
P80 Natural Essence Exerts Efficient Anti-HIV-1- as Well as Adjuvant Effects in DCs. Vaccines 9 (9) (2021)
Michael W Hess, Iris M Krainer, Przemyslaw A Filipek, Barbara Witting, Karin Gutleben, Ilja Vietor, Heinz Zoller, Denise Aldrian, Ekkehard Sturm, James R Goldenring, Andreas R Janecke, Rupert Oberhuber, Lukas A Huber, Georg-Friedrich Vogel
Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations. Journal of clinical medicine 10 (9) (2021)
Cecilia Cattelani, Dominik Lesiak, Gudrun Liebscher, Isabel I Singer, Taras Stasyk, Moritz H Wallnöfer, Alexander Martin Heberle, Corrado Corti, Michael W Hess, Kristian Pfaller, Marcel Kwiatkowski, Peter P Pramstaller, Andrew A Hicks, Kathrin Thedieck, Thomas Müller, Lukas A Huber, Mariana E G de Araujo
The SZT2 Interactome Unravels New Functions of the KICSTOR Complex. Cells 10 (10) (2021)
Teodor E Yordanov, Victoria E B Hipolito, Gudrun Liebscher, Georg F Vogel, Taras Stasyk, Caroline Herrmann, Stephan Geley, David Teis, Roberto J Botelho, Michael W Hess, Lukas A Huber
Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate. Traffic (Copenhagen, Denmark) 20 (9) (2020)
Gennaro Napolitano, Chiara Di Malta, Alessandra Esposito, Mariana E G de Araujo, Salvatore Pece, Giovanni Bertalot, Maria Matarese, Valerio Benedetti, Angela Zampelli, Taras Stasyk, Diletta Siciliano, Alessandro Venuta, Marcella Cesana, Claudia Vilardo, Edoardo Nusco, Jlenia Monfregola, Alessia Calcagni', Pier Paolo Di Fiore, Lukas A Huber, Andrea Balabio
A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome. Nature 585 (7826) (2020)
Mariana E G de Araujo, Gudrun Liebscher, Michael W Hess, Lukas A Huber
Lysosomal size matters. Traffic (Copenhagen, Denmark) 21 (1) (2019)
Mariana E G de Araujo, Andreas Naschberger, Barbara G Fürnrohr, Taras Stasyk, Theresia Dunzendorfer-Matt, Stefan Lechner, Stefan Welti, Leopold Kremser, Giridhar Shivalingaiah, Martin Offterdinger, Herbert H Lindner, Lukas A Huber, Klaus Scheffzek
Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling. Science (New York, N.Y.) 358 (6361) (2017)
Przemyslaw A Filipek, Mariana E G de Araujo, Georg F Vogel, Cedric H De Smet, Daniela Eberharter, Manuele Rebsamen, Elena L Rudashevskaya, Leopold Kremser, Teodor E Yordanov, Philipp Tschaikner, Barbara G Fürnrohr, Stefan Lechner, Theresia Dunzendorfer-Matt, Klaus Scheffzek, Keiryn L Bennett, Giulio Superti-Furga, Herbert H Lindner, Taras Stasyk, Lukas A Huber
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning. The Journal of cell biology 216 (12) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Lukas A Huber