Megan T Baldridge

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 38

Top Venues

Washington University School of Medicine

Baylor College of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University School of Medicine Jul 01 2016

United States

Assistant Professor :: Medicine, Infectious Diseases

Washington University School of Medicine Jun 15 2011 - Jun 30 2016

United States

Postdoctoral Researcher :: Pathology & Immunology

Education History

Baylor College of Medicine

United States

PHD :: Molecular & Human Genetics

Publications

Somya Aggarwal, Forrest C Walker, James S Weagley, Broc T McCune, Xiaofen Wu, Lawrence A Schriefer, Heyde Makimaa, Dylan Lawrence, Pratyush Sridhar, Megan T Baldridge
Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection. PLoS pathogens 20 (5) (2024)
Somya Aggarwal, Forrest C Walker, James S Weagley, Broc T McCune, Xiaofen Wu, Lawrence A Schriefer, Heyde Makimaa, Dylan Lawrence, Pratyush Sridhar, Megan T Baldridge
Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection. PLoS pathogens 20 (5) (2024)
Somya Aggarwal, Forrest C Walker, James S Weagley, Broc T McCune, Xiaofen Wu, Lawrence A Schriefer, Heyde Makimaa, Dylan Lawrence, Pratyush Sridhar, Megan T Baldridge
Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection. PLoS pathogens 20 (5) (2024)
Yuhao Li, Megan T Baldridge
Modelling human immune responses using microbial exposures in rodents. Nature microbiology (2023)
Elizabeth A Kennedy, Somya Aggarwal, Arko Dhar, Stephanie M Karst, Craig B Wilen, Megan T Baldridge
Age-associated features of norovirus infection analysed in mice. Nature microbiology (2023)
Harshad Ingle, Heyde Makimaa, Somya Aggarwal, Hongju Deng, Lynne Foster, Yuhao Li, Elizabeth A Kennedy, Stefan T Peterson, Craig B Wilen, Sanghyun Lee, Mehul S Suthar, Megan T Baldridge
IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus. Science advances 9 (37) (2023)
Marija S Nadjsombati, Natalie Niepoth, Lily M Webeck, Elizabeth A Kennedy, Danielle L Jones, Tyler E Billipp, Megan T Baldridge, Andres Bendesky, Jakob von Moltke
Genetic mapping reveals Pou2af2/ OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science immunology 8 (83) (2023)
Marija S Nadjsombati, Natalie Niepoth, Lily M Webeck, Elizabeth A Kennedy, Danielle L Jones, Tyler E Billipp, Megan T Baldridge, Andres Bendesky, Jakob von Moltke
Genetic mapping reveals Pou2af2/ OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science immunology 8 (83) (2023)
Yuhao Li, Megan T Baldridge
Modelling human immune responses using microbial exposures in rodents. Nature microbiology 8 (3) (2023)
Marija S Nadjsombati, Natalie Niepoth, Lily M Webeck, Elizabeth A Kennedy, Danielle L Jones, Tyler E Billipp, Megan T Baldridge, Andres Bendesky, Jakob von Moltke
Genetic mapping reveals Pou2af2/ OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science immunology 8 (83) (2023)
Yuhao Li, Megan T Baldridge
Modelling human immune responses using microbial exposures in rodents. Nature microbiology (2023)
Yuhao Li, Jerome M Molleston, Andrew H Kim, Harshad Ingle, Somya Aggarwal, Lila S Nolan, Ahmed O Hassan, Lynne Foster, Michael S Diamond, Megan T Baldridge
Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination. bioRxiv : the preprint server for biology (2023)
Amy M Peiper, Emily W Helm, Quyen Nguyen, Matthew Phillips, Caroline G Williams, Dhairya Shah, Sarah Tatum, Neha Iyer, Marco Grodzki, Laura B Eurell, Aqsa Nasir, Megan T Baldridge, Stephanie M Karst
Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis. Lab animal (2023)
Yuhao Li, Megan T Baldridge
Modelling human immune responses using microbial exposures in rodents. Nature microbiology 8 (3) (2023)
Kentaro Yomogida, Tihana Trsan, Raki Sudan, Patrick Fernandes Rodrigues, Alina Ulezko Antonova, Harshad Ingle, Blanda Di Luccia, Patrick L Collins, Marina Cella, Susan Gilfillan, Megan T Baldridge, Eugene M Oltz, Marco Colonna
The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes. Nature immunology (2023)
Yuhao Li, Megan T Baldridge
Modelling human immune responses using microbial exposures in rodents. Nature microbiology 8 (3) (2023)
Marija S Nadjsombati, Natalie Niepoth, Lily M Webeck, Elizabeth A Kennedy, Danielle L Jones, Tyler E Billipp, Megan T Baldridge, Andres Bendesky, Jakob von Moltke
Genetic mapping reveals Pou2af2/ OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science immunology 8 (83) (2023)
Iti Saraav, Luisa Cervantes-Barragan, Philipp Olias, Yong Fu, Qiuling Wang, Leran Wang, Yi Wang, Matthias Mack, Megan T Baldridge, Thaddeus Stappenbeck, Marco Colonna, L David Sibley
Chronic Toxoplasma gondii infection enhances susceptibility to colitis. Proceedings of the National Academy of Sciences of the United States of America 118 (36) (2022)
Dylan Lawrence, Danielle E Campbell, Lawrence A Schriefer, Rachel Rodgers, Forrest C Walker, Marissa Turkin, Lindsay Droit, Miles Parkes, Scott A Handley, Megan T Baldridge
Single-cell genomics for resolution of conserved bacterial genes and mobile genetic elements of the human intestinal microbiota using flow cytometry. Gut microbes 14 (1) (2022)
Jacob A Van Winkle, Stefan T Peterson, Elizabeth A Kennedy, Michael J Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A Constant, Austin P Wright, Lena Li, Maxim N Artyomov, Sanghyun Lee, Megan T Baldridge, Timothy J Nice
Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium. eLife 11 (2022)
Meagan E Sullender, Linley R Pierce, Mridula Annaswamy Srinivas, Stacey L Crockett, Bria F Dunlap, Rachel Rodgers, Lawrence A Schriefer, Elizabeth A Kennedy, Brittany M Stewart, John G Doench, Megan T Baldridge, Robert C Orchard
Selective Polyprotein Processing Determines Norovirus Sensitivity to Trim7. Journal of virology 96 (17) (2022)
Hannah Yan, Forrest C Walker, Arushana Ali, Hyojeong Han, Lin Tan, Lucas Veillon, Philip L Lorenzi, Megan T Baldridge, Katherine Y King
The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling. Blood advances 6 (6) (2022)
Sanghyun Lee, Gowri Kalugotla, Harshad Ingle, Rachel Rodgers, Chunyan Wu, Yating Wang, Yuhao Li, Xia Yang, Jin Zhang, Nicolette R Borella, Hongju Deng, Lindsay Droit, Ryan Hill, Stefan T Peterson, Chandni Desai, Dylan Lawrence, Qun Lu, Megan T Baldridge
Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota. Autophagy (2021)
Vincent R Graziano, Mia Madel Alfajaro, Cameron O Schmitz, Renata B Filler, Madison S Strine, Jin Wei, Leon L Hsieh, Megan T Baldridge, Timothy J Nice, Sanghyun Lee, Robert C Orchard, Craig B Wilen
CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus. Journal of virology 95 (3) (2021)
Forrest C Walker, Ebrahim Hassan, Stefan T Peterson, Rachel Rodgers, Lawrence A Schriefer, Cassandra E Thompson, Yuhao Li, Gowri Kalugotla, Carla Blum-Johnston, Dylan Lawrence, Broc T McCune, Vincent R Graziano, Larissa Lushniak, Sanghyun Lee, Alexa N Roth, Stephanie M Karst, Timothy J Nice, Jonathan J Miner, Craig B Wilen, Megan T Baldridge
Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid. PLoS pathogens 17 (3) (2021)
Harshad Ingle, Ebrahim Hassan, Jana Gawron, Belgacem Mihi, Yuhao Li, Elizabeth A Kennedy, Gowri Kalugotla, Heyde Makimaa, Sanghyun Lee, Pritesh Desai, Keely G McDonald, Michael S Diamond, Rodney D Newberry, Misty Good, Megan T Baldridge
Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures. Mucosal immunology 14 (3) (2021)
Somya Aggarwal, Ebrahim Hassan, Megan T Baldridge
Experimental Methods to Study the Pathogenesis of Human Enteric RNA Viruses. Viruses 13 (6) (2021)
Sanghyun Lee, Megan T Baldridge
Viruses RIG up intestinal immunity. Nature immunology 20 (12) (2020)
Heyde Makimaa, Harshad Ingle, Megan T Baldridge
Enteric Viral Co-Infections: Pathogenesis and Perspective. Viruses 12 (8) (2020)
Ya Ting Wang, Konstantin Zaitsev, Qun Lu, Shan Li, W Timothy Schaiff, Ki-Wook Kim, Lindsay Droit, Craig B Wilen, Chandni Desai, Dale R Balce, Robert C Orchard, Anthony Orvedahl, Sunmin Park, Darren Kreamalmeyer, Scott A Handley, John D Pfeifer, Megan T Baldridge, Maxim N Artyomov, Christina L Stallings, Herbert W Virgin
Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes. Nature microbiology 5 (2) (2020)
Vincent R Graziano, Forrest C Walker, Elizabeth A Kennedy, Jin Wei, Khalil Ettayebi, Madison S Strine, Renata B Filler, Ebrahim Hassan, Leon L Hsieh, Arthur S Kim, Abimbola O Kolawole, Christiane E Wobus, Lisa C Lindesmith, Ralph S Baric, Mary K Estes, Robert C Orchard, Megan T Baldridge, Craig B Wilen
CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus. PLoS pathogens 16 (4) (2020)
Harshad Ingle, Sanghyun Lee, Teresa Ai, Anthony Orvedahl, Rachel Rodgers, Guoyan Zhao, Meagan Sullender, Stefan T Peterson, Marissa C Locke, Ta-Chiang Liu, Christine C Yokoyama, Bridgett Sharp, Stacey Schultz-Cherry, Jonathan J Miner, Megan T Baldridge
Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ. Nature microbiology 4 (7) (2019)
Katrina R Grau, Shu Zhu, Stefan T Peterson, Emily W Helm, Drake Philip, Matthew Phillips, Abel Hernandez, Holly Turula, Philip M Frasse, Vincent R Graziano, Craig B Wilen, Christiane E Wobus, Megan T Baldridge, Stephanie M Karst
The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon. Nature microbiology 5 (1) (2019)
Meagan E Sullender, Megan T Baldridge
Norovirus interactions with the commensal microbiota. PLoS pathogens 14 (9) (2018)
Harshad Ingle, Stefan T Peterson, Megan T Baldridge
Distinct Effects of Type I and III Interferons on Enteric Viruses. Viruses 10 (1) (2018)
Hannah Yan, Megan T Baldridge, Katherine Y King
Hematopoiesis and the bacterial microbiome. Blood 132 (6) (2018)
Craig B Wilen, Sanghyun Lee, Leon L Hsieh, Robert C Orchard, Chandani Desai, Barry L Hykes, Michael R McAllaster, Dale R Balce, Taylor Feehley, Jonathan Robert Brestoff, Christina A Hickey, Christine C Yokoyama, Ya Ting Wang, Donna A MacDuff, Darren Kreamalmayer, Michael R Howitt, Jessica A Neil, Ken H Cadwell, Paul M Allen, Scott A Handley, Menno van Lookeren Campagne, Megan T Baldridge, Herbert W Virgin
Tropism for tuft cells determines immune promotion of norovirus pathogenesis. Science (New York, N.Y.) 360 (6385) (2018)
Kamilla S Josefsdottir, Megan T Baldridge, Claudine S Kadmon, Katherine Y King
Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota. Blood 129 (6) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Megan T Baldridge