Philip L Lorenzi (Philip Lorenzi)

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 70

Top Topics

Breast Cancer Cells

Top Venues

Nature communications

Research square

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Aaron S Schwartz-Duval, Yuri Mackeyev, Iqbal Mahmud, Philip L Lorenzi, Mihai Gagea, Sunil Krishnan, Konstantin V Sokolov
Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization. ACS nano 18 (3) (2024)
Arseniy E Yuzhalin, Frank J Lowery, Yohei Saito, Xiangliang Yuan, Jun Yao, Yimin Duan, Jingzhen Ding, Sunil Acharya, Chenyu Zhang, Abigail Fajardo, Hao-Nien Chen, Yongkun Wei, Yutong Sun, Lin Zhang, Yi Xiao, Ping Li, Philip L Lorenzi, Jason T Huse, Huihui Fan, Zhong-Ming Zhao, Mien-Chie Hung, Dihua Yu
Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition. Nature cell biology (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Hyemin Lee, Amber D Horbath, Lavanya Kondiparthi, Jitendra Kumar Meena, Guang Lei, Shayani Dasgupta, Xiaoguang Liu, Li Zhuang, Pranavi Koppula, Mi Li, Iqbal Mahmud, Bo Wei, Philip L Lorenzi, Khandan Keyomarsi, Masha V Poyurovsky, Kellen Olszewski, Boyi Gan
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nature communications 15 (1) (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma. Cancer research (2024)
Aaron S Schwartz-Duval, Yuri Mackeyev, Iqbal Mahmud, Philip L Lorenzi, Mihai Gagea, Sunil Krishnan, Konstantin V Sokolov
Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization. ACS nano (2024)
Aaron S Schwartz-Duval, Yuri Mackeyev, Iqbal Mahmud, Philip L Lorenzi, Mihai Gagea, Sunil Krishnan, Konstantin V Sokolov
Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization. ACS nano 18 (3) (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma. Cancer research (2024)
Jessica B Felix, Pradip K Saha, Evelyn de Groot, Lin Tan, Robert Sharp, Elizabeth S Anaya, Yafang Li, Holly Quang, Nooshin Saidi, Layla Abushamat, Christie M Ballantyne, Christopher Ian Amos, Philip L Lorenzi, Samuel Klein, Xia Gao, Sean M Hartig
N-acetylaspartate from fat cells regulates postprandial body temperature. Research square (2024)
Jessica Felix, Pradip Saha, Evelyn de Groot, Lin Tan, Robert Sharp, Elizabeth Anaya, Yafang Li, Holly Quang, Nooshin Saidi, Layla Abushamat, Christie M Ballantyne, Christopher Ian Amos, Philip L Lorenzi, Samuel Klein, Xia Gao, Sean M Hartig
N-acetylaspartate from fat cells regulates postprandial body temperature. Research square (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 Control Lipid Metabolism to Support the Development of Clear Cell Renal Cell Carcinoma. Cancer research 84 (13) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Sean M Hartig, Jessica Felix, Pradip Saha, Evelyn de Groot, Lin Tan, Robert Sharp, Elizabeth Anaya, Yafang Li, Holly Quang, Nooshin Saidi, Layla Abushamat, Christie M Ballantyne, Christopher Ian Amos, Philip L Lorenzi, Samuel Klein, Xia Gao
N-acetylaspartate from fat cells regulates postprandial body temperature. Research square (2024)
Aaron S Schwartz-Duval, Yuri Mackeyev, Iqbal Mahmud, Philip L Lorenzi, Mihai Gagea, Sunil Krishnan, Konstantin V Sokolov
Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization. ACS nano 18 (3) (2024)
Aaron S Schwartz-Duval, Yuri Mackeyev, Iqbal Mahmud, Philip L Lorenzi, Mihai Gagea, Sunil Krishnan, Konstantin V Sokolov
Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization. ACS nano 18 (3) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 Control Lipid Metabolism to Support the Development of Clear Cell Renal Cell Carcinoma. Cancer research 84 (13) (2024)
Hyemin Lee, Amber D Horbath, Lavanya Kondiparthi, Jitendra Kumar Meena, Guang Lei, Shayani Dasgupta, Xiaoguang Liu, Li Zhuang, Pranavi Koppula, Mi Li, Iqbal Mahmud, Bo Wei, Philip L Lorenzi, Khandan Keyomarsi, Masha V Poyurovsky, Kellen Olszewski, Boyi Gan
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nature communications 15 (1) (2024)
Jessica B Felix, Pradip K Saha, Evelyn de Groot, Lin Tan, Robert Sharp, Elizabeth S Anaya, Yafang Li, Holly Quang, Nooshin Saidi, Layla Abushamat, Christie M Ballantyne, Christopher Ian Amos, Philip L Lorenzi, Samuel Klein, Xia Gao, Sean M Hartig
N-acetylaspartate from fat cells regulates postprandial body temperature. Research square (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 Control Lipid Metabolism to Support the Development of Clear Cell Renal Cell Carcinoma. Cancer research 84 (13) (2024)
Hyemin Lee, Amber D Horbath, Lavanya Kondiparthi, Jitendra Kumar Meena, Guang Lei, Shayani Dasgupta, Xiaoguang Liu, Li Zhuang, Pranavi Koppula, Mi Li, Iqbal Mahmud, Bo Wei, Philip L Lorenzi, Khandan Keyomarsi, Masha V Poyurovsky, Kellen Olszewski, Boyi Gan
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nature communications 15 (1) (2024)
Hyemin Lee, Amber D Horbath, Lavanya Kondiparthi, Jitendra Kumar Meena, Guang Lei, Shayani Dasgupta, Xiaoguang Liu, Li Zhuang, Pranavi Koppula, Mi Li, Iqbal Mahmud, Bo Wei, Philip L Lorenzi, Khandan Keyomarsi, Masha V Poyurovsky, Kellen Olszewski, Boyi Gan
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nature communications 15 (1) (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma. Cancer research (2024)
Hyemin Lee, Amber D Horbath, Lavanya Kondiparthi, Jitendra Kumar Meena, Guang Lei, Shayani Dasgupta, Xiaoguang Liu, Li Zhuang, Pranavi Koppula, Mi Li, Iqbal Mahmud, Bo Wei, Philip L Lorenzi, Khandan Keyomarsi, Masha V Poyurovsky, Kellen Olszewski, Boyi Gan
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nature communications 15 (1) (2024)
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina Toffessi Tcheuyap, James Brugarolas, Scott M Welford
GPR1 and CMKLR1 Control Lipid Metabolism to Support the Development of Clear Cell Renal Cell Carcinoma. Cancer research 84 (13) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Dianna M Milewicz, Anita Kaw, Ting Wu, Zbigniew Starosolski, Zhen Zhou, Albert J Pedroza, Suravi Majumder, Xue-Yan Duan, Kaveeta Kaw, Jose Esparza Pinelo, Michael P Fischbein, Philip L Lorenzi, Lin Tan, Sara Martinez, Iqbal Mahmud, Laxman Devkota, Heinrich Taegtmeyer, Ketan Ghaghada, Sean Marrelli, Callie S Kwartler
Augmenting Mitochondrial Respiration in Immature Smooth Muscle Cells with an ACTA2 Pathogenic Variant Mitigates Moyamoya-like Cerebrovascular Disease. Research square (2023)
Peter M Masschelin, Pradip Saha, Scott A Ochsner, Aaron R Cox, Kang Ho Kim, Jessica B Felix, Robert Sharp, Xin Li, Lin Tan, Jun Hyoung Park, Liping Wang, Vasanta Putluri, Philip L Lorenzi, Alli M Nuotio-Antar, Zheng Sun, Benny Abraham Kaipparettu, Nagireddy Putluri, David D Moore, Scott A Summers, Neil J McKenna, Sean M Hartig
Vitamin B2 enables regulation of fasting glucose availability. eLife 12 (2023)
Mokryun L Baek, Junegoo Lee, Katherine E Pendleton, Mariah J Berner, Emily B Goff, Lin Tan, Sara A Martinez, Iqbal Mahmud, Tao Wang, Matthew D Meyer, Bora Lim, James P Barrish, Weston Porter, Philip L Lorenzi, Gloria V Echeverria
Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment. Oncogene (2023)
Steven W Wall, Lilia Sanchez, Kelly Scribner Tuttle, Scott J Pearson, Shivatheja Soma, Garhett L Wyatt, Hannah N Carter, Ramsey M Jenschke, Lin Tan, Sara A Martinez, Philip L Lorenzi, Vishal M Gohil, Monique Rijnkels, Weston W Porter
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer. Experimental & molecular medicine (2023)
Steven W Wall, Lilia Sanchez, Kelly Scribner Tuttle, Scott J Pearson, Shivatheja Soma, Garhett L Wyatt, Hannah N Carter, Ramsey M Jenschke, Lin Tan, Sara A Martinez, Philip L Lorenzi, Vishal M Gohil, Monique Rijnkels, Weston W Porter
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer. Experimental & molecular medicine (2023)
Susmita Ghosh, Fan Fan, Reid T Powell, Jason Roszik, Yongsung Park, Clifford Stephen, Manu Sebastian, Lin Tan, Alexey V Sorokin, Philip L Lorenzi, Edmund S Kopetz, Lee M Ellis, Rajat Bhattacharya
Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer. Molecular cancer therapeutics (2023)
Robert R Jenq, Eiko Hayase, Tomo Hayase, Akash Mukherjee, Stuart Stinson, Mohamed Jamal, Miriam Ortega, Christopher Sanchez, Saira Ahmed, Jennifer Karmouch, Chia-Chi Chang, Ivonne Flores, Lauren McDaniel, Alexandria Brown, Rawan El-Himri, Valerie Chapa, Lin Tan, Bao Tran, Dung Pham, Taylor Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Israel Glover, Nadim Ajami, Jennifer A Wargo, Samuel Shelburne, Pablo C Okhuysen, Chen Liu, Stephanie Fowler, Margaret Conner, Christine B Peterson, Gabriela Rondon, Jeffrey J Molldrem, Richard Champlin, Elizabeth Shpall, Philip L Lorenzi, Rohtesh Mehta, Eric C Martens, Amin Alousi
Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease. Research square (2023)
Daoyan Wei, Dongmei Chen, Hongyuan Mou, Sharmistha Chakraborty, Bo Wei, Lin Tan, Philip L Lorenzi, Xiangping Qian, Peiying Yang
Targeting Glutamine Metabolism with a Novel Na+/K+-ATPase Inhibitor RX108 in Hepatocellular Carcinoma. Molecular cancer therapeutics (2023)
Mokryun L Baek, Junegoo Lee, Katherine E Pendleton, Mariah J Berner, Emily B Goff, Lin Tan, Sara A Martinez, Iqbal Mahmud, Tao Wang, Matthew D Meyer, Bora Lim, James P Barrish, Weston Porter, Philip L Lorenzi, Gloria V Echeverria
Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment. Oncogene (2023)
Sara Corvigno, Sunil Badal, Meredith L Spradlin, Michael Keating, Igor Pereira, Elaine Stur, Emine Bayraktar, Katherine I Foster, Nicholas W Bateman, Waleed Barakat, Kathleen M Darcy, Thomas P Conrads, G Larry Maxwell, Philip L Lorenzi, Susan K Lutgendorf, Yunfei Wen, Li Zhao, Premal H Thaker, Michael J Goodheart, Jinsong Liu, Nicole Fleming, Sanghoon Lee, Livia S Eberlin, Anil K Sood
In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy. NPJ precision oncology 7 (1) (2023)
Ziheng Chen, I-Lin Ho, Melinda Soeung, Er-Yen Yen, Jintan Liu, Liang Yan, Johnathon L Rose, Sanjana Srinivasan, Shan Jiang, Q Edward Chang, Ningping Feng, Jason P Gay, Qi Wang, Jing Wang, Philip L Lorenzi, Lucas J Veillon, Bo Wei, John N Weinstein, Angela K Deem, Sisi Gao, Giannicola Genovese, Andrea Viale, Wantong Yao, Costas Andreas Lyssiotis, Joseph R Marszalek, Giulio F Draetta, Haoqiang Ying
Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis. Nature communications 14 (1) (2023)
Jovanka Gencel-Augusto, Xiaoping Su, Yuan Qi, Elizabeth M Whitley, Vinod Pant, Shunbin Xiong, Vrutant V Shah, Jerome Lin, Encarnacion Perez, Marta L Fiorotto, Iqbal Mahmud, Abhinav K Jain, Philip L Lorenzi, Nicholas E Navin, Ellen R Richie, Guillermina Lozano
Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer discovery (2023)
Lin Tan, Sara A Martinez, Philip L Lorenzi, Anja Karlstaedt
Quantitative Analysis of Acetyl-CoA, Malonyl-CoA, and Succinyl-CoA in Myocytes. Journal of the American Society for Mass Spectrometry (2023)
Robert R Jenq, Eiko Hayase, Tomo Hayase, Akash Mukherjee, Stuart Stinson, Mohamed Jamal, Miriam Ortega, Christopher Sanchez, Saira Ahmed, Jennifer Karmouch, Chia-Chi Chang, Ivonne Flores, Lauren McDaniel, Alexandria Brown, Rawan El-Himri, Valerie Chapa, Lin Tan, Bao Tran, Dung Pham, Taylor Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Israel Glover, Nadim Ajami, Jennifer A Wargo, Samuel Shelburne, Pablo C Okhuysen, Chen Liu, Stephanie Fowler, Margaret Conner, Christine B Peterson, Gabriela Rondon, Jeffrey J Molldrem, Richard Champlin, Elizabeth Shpall, Philip L Lorenzi, Rohtesh Mehta, Eric C Martens, Amin Alousi
Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease. Research square (2023)
Yifan Wang, Weiye Deng, DaeYong Lee, Long Yan, Yifei Lu, Shiyan Dong, Kristin M Huntoon, Abin Antony, Xuefeng Li, Rui Ye, Yan Zhao, Feiyan Zhao, Benjamin R Schrank, JongHoon Ha, Minjeong Kang, Mingming Yang, Ping Gong, Philip L Lorenzi, Lin Tan, Thomas D Gallup, Sarah K Tang, Zhaogang Yang, Jing Li, Nina N Sanford, Hongmei Wang, Yon Son Betty Kim, Wen Jiang
Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics. Nature nanotechnology (2023)
Steven W Wall, Lilia Sanchez, Kelly Scribner Tuttle, Scott J Pearson, Shivatheja Soma, Garhett L Wyatt, Hannah N Carter, Ramsey M Jenschke, Lin Tan, Sara A Martinez, Philip L Lorenzi, Vishal M Gohil, Monique Rijnkels, Weston W Porter
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer. Experimental & molecular medicine (2023)
Robert R Jenq, Eiko Hayase, Tomo Hayase, Akash Mukherjee, Stuart Stinson, Mohamed Jamal, Miriam Ortega, Christopher Sanchez, Saira Ahmed, Jennifer Karmouch, Chia-Chi Chang, Ivonne Flores, Lauren McDaniel, Alexandria Brown, Rawan El-Himri, Valerie Chapa, Lin Tan, Bao Tran, Dung Pham, Taylor Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Israel Glover, Nadim Ajami, Jennifer A Wargo, Samuel Shelburne, Pablo C Okhuysen, Chen Liu, Stephanie Fowler, Margaret Conner, Christine B Peterson, Gabriela Rondon, Jeffrey J Molldrem, Richard Champlin, Elizabeth Shpall, Philip L Lorenzi, Rohtesh Mehta, Eric C Martens, Amin Alousi
Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease. Research square (2023)
Steven W Wall, Lilia Sanchez, Kelly Scribner Tuttle, Scott J Pearson, Shivatheja Soma, Garhett L Wyatt, Hannah N Carter, Ramsey M Jenschke, Lin Tan, Sara A Martinez, Philip L Lorenzi, Vishal M Gohil, Monique Rijnkels, Weston W Porter
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer. Experimental & molecular medicine (2023)
Gang Li, Xin Li, Li Yang, Shuyue Wang, Yulin Dai, Baharan Fekry, Lucas Veillon, Lin Tan, Rebecca Berdeaux, Kristin Eckel-Mahan, Philip L Lorenzi, Zhong-Ming Zhao, Richard Lehner, Kai Sun
Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice. Life science alliance 5 (8) (2022)
Casey T Finnicum, Zahraa Rahal, Maya Hassane, Warapen Treekitkarnmongkol, Ansam Sinjab, Rhiannon Morris, Yuejiang Liu, Elizabeth L Tang, Sarah Viet, Jason L Petersen, Philip L Lorenzi, Lin Tan, Joseph Petrosino, Kristi L Hoffman, Junya Fujimoto, Seyed Javad Moghaddam, Humam Kadara
Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes. International journal of molecular sciences 23 (18) (2022)
Natalia Baran, Alessia Lodi, Yogesh Dhungana, Shelley Herbrich, Meghan E Collins, Shannon Sweeney, Renu Pandey, Anna Skwarska, Shraddha Patel, Mathieu Tremblay, Vinitha Mary Kuruvilla, Antonio Cavazos, Mecit Kaplan, Marc O Warmoes, Diogo Troggian Veiga, Ken Furudate, Shanti Rojas-Sutterin, Andre Haman, Yves Gareau, Anne Marinier, Helen Ma, Karine Harutyunyan, May Daher, Luciana Melo Garcia, Gheath Al-Atrash, Sujan Piya, Vivian Ruvolo, Wentao Yang, Sriram Saravanan Shanmugavelandy, Ningping Feng, Jason Gay, Di Du, Jun J Yang, Fieke W Hoff, Marcin Mikołaj Kamiński, Katarzyna Tomczak, Richard Eric Davis, Daniel Herranz, Adolfo A Ferrando, Elias J Jabbour, M Emilia Di Francesco, David Trent Teachey, Terzah M Horton, Steven Mitchell Kornblau, Katayoun Rezvani, Guy Sauvageau, Mihai Gagea, Michael Andreeff, Koichi Takahashi, Joseph R Marszalek, Philip L Lorenzi, Jiyang Yu, Stefano Tiziani, Trang Hoang, Marina Y Konopleva
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nature communications 13 (1) (2022)
Xiaoding Wang, Guangyu Zhang, Subhajit Dasgupta, Erica L Niewold, Chao Li, Qinfeng Li, Xiang Luo, Lin Tan, Anwarul Ferdous, Philip L Lorenzi, Beverly A Rothermel, Thomas G Gillette, Christopher M Adams, Philipp E Scherer, Joseph A Hill, Zhao V Wang
ATF4 Protects the Heart From Failure by Antagonizing Oxidative Stress. Circulation research 131 (1) (2022)
Zaker I Schwabkey, Diana H Wiesnoski, Chia-Chi Chang, Wen-Bin Tsai, Dung Pham, Saira S Ahmed, Tomo Hayase, Miriam R Ortega Turrubiates, Rawan K El-Himri, Christopher A Sanchez, Eiko Hayase, Annette C Frenk Oquendo, Takahiko Miyama, Taylor M Halsey, Brooke E Heckel, Alexandria N Brown, Yimei Jin, Mathilde Raybaud, Rishika Prasad, Ivonne Flores, Lauren McDaniel, Valerie Chapa, Philip L Lorenzi, Marc O Warmoes, Lin Tan, Alton G Swennes, Stephanie Fowler, Margaret E Conner, Kevin J McHugh, Tyler P Graf, Vanessa B Jensen, Christine B Peterson, Kim-Anh Do, Liangliang Zhang, Yushu Shi, Yinghong Wang, Jessica R Galloway-Peña, Pablo C Okhuysen, Carrie R Daniel-MacDougall, Yusuke Shono, Marina Burgos da Silva, Jonathan U Peled, Marcel R M van den Brink, Nadim J Ajami, Jennifer A Wargo, Pavan Reddy, Raphael H Valdivia, Lauren E Davey, Gabriela Rondon, Samer A Srour, Rohtesh S Mehta, Amin M Alousi, Elizabeth J Shpall, Richard E Champlin, Samuel A Shelburne Iii, Jeffrey J Molldrem, Mohamed A Jamal, Jennifer L Karmouch, Robert R Jenq
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Science translational medicine 14 (671) (2022)
Manuel Grima-Reyes, Ashaina Vandenberghe, Ivan Nemazanyy, Pauline Meola, Rachel Paul, Julie Reverso-Meinietti, Adriana Martinez Turtos, Nicolas Nottet, Wai-Kin Chan, Philip L Lorenzi, Sandrine Marchetti, Jean-Ehrland Ricci, Johanna Chiche
Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression. Science advances 8 (27) (2022)
Hannah Yan, Forrest C Walker, Arushana Ali, Hyojeong Han, Lin Tan, Lucas Veillon, Philip L Lorenzi, Megan T Baldridge, Katherine Y King
The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling. Blood advances 6 (6) (2022)
Jessica I Sanchez, Jingjing Jiao, Suet-Ying Kwan, Lucas Veillon, Marc O Warmoes, Lin Tan, Mobolaji Odewole, Nicole E Rich, Peng Wei, Philip L Lorenzi, Amit G Singal, Laura Beretta
Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis. Cancer prevention research (Philadelphia, Pa.) 14 (10) (2021)
Bingbing Dai, Jithesh J Augustine, Ya'an Kang, David Roife, Xinqun Li, Jenying Deng, Lin Tan, Leona A Rusling, John N Weinstein, Philip L Lorenzi, Michael P Kim, Jason B Fleming
Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway. Cell death & disease 12 (7) (2021)
Francesca Puca, Fei Yu, Caterina Bartolacci, Piergiorgio Pettazzoni, Alessandro Carugo, Emmet Huang-Hobbs, Jintan Liu, Ciro Zanca, Federica Carbone, Edoardo Del Poggetto, Joy Gumin, Pushan Dasgupta, Sahil B Seth, Sanjana Srinivasan, Frederick F Lang, Erik P Sulman, Philip L Lorenzi, Lin Tan, Mengrou Shan, Zachary P Tolstyka, Maureen Kachman, Li Zhang, Sisi Gao, Angela K Deem, Giannicola Genovese, Pier Paolo Scaglioni, Costas Andreas Lyssiotis, Andrea Viale, Giulio F Draetta
Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma. Cancer discovery 11 (11) (2021)
Jingjing Jiao, Suet-Ying Kwan, Caroline M Sabotta, Honami Tanaka, Lucas Veillon, Marc O Warmoes, Philip L Lorenzi, Ying Wang, Peng Wei, Ernest T Hawk, Jose Luis Almeda, Joseph B McCormick, Susan P Fisher-Hoch, Laura Beretta
Circulating Fatty Acids Associated with Advanced Liver Fibrosis and Hepatocellular Carcinoma in South Texas Hispanics. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 30 (9) (2021)
Jacek Lubkowski, Juan M Vanegas, Wai-Kin Chan, Philip L Lorenzi, John N Weinstein, Sergei Sukharev, David Fushman, Susan Rempe, Andriy Anishkin, Alexander Wlodawer
Mechanism of Catalysis by l-Asparaginase. Biochemistry 59 (20) (2020)
Sherille D Bradley, Amjad H Talukder, Ivy Lai, Rebecca Davis, Hector Alvarez, Herve Tiriac, Minying Zhang, Yulun Chiu, Brenda Melendez, Kyle R Jackson, Arjun Katailiha, Heather M Sonnemann, Fenge Li, Yaan Kang, Na Qiao, Bih-Fang Pan, Philip L Lorenzi, Mark W Hurd, Elizabeth A Mittendorf, Christine B Peterson, Milind Javle, Christopher Bristow, Michael Kim, David A Tuveson, David H Hawke, Edmund S Kopetz, Robert A Wolff, Patrick Hwu, Anirban Maitra, Jason Roszik, Cassian Yee, Gregory Lizée
Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers. Nature communications 11 (1) (2020)
Liang Zhang, Yixin Yao, Shaojun Zhang, Yang Liu, Hui Guo, Makhdum Ahmed, Taylor Bell, Hui Zhang, Guangchun Han, Elizabeth Lorence, Maria Badillo, Shouhao Zhou, Yuting Sun, Maria Emilia Di Francesco, Ningping Feng, Randy Haun, Renny Shang-Lun Lan, Samuel G Mackintosh, Xizeng Mao, Xingzhi Song, Jianhua Zhang, Lan V Pham, Philip L Lorenzi, Joseph R Marszalek, Timothy P Heffernan, Giulio F Draetta, Philip Jones, P Andrew Futreal, Krystle Nomie, Linghua Wang, Michael L Wang
Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma. Science translational medicine 11 (491) (2020)
Sruthy Varghese, Snigdha Pramanik, Leila J Williams, Hannah R Hodges, Courtney W Hudgens, Grant M Fischer, Catherine K Luo, Barbara Knighton, Lin Tan, Philip L Lorenzi, Andrew L Mackinnon, Jennifer Leigh McQuade, Yared Hailemichael, Jason Roszik, Weiyi Peng, Y N Vashisht Gopal
The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell-Mediated Immunotherapies. Molecular cancer therapeutics 20 (3) (2020)
Wai-Kin Chan, Thomas D Horvath, Lin Tan, Todd Link, Karine G Harutyunyan, Michael A Pontikos, Andriy Anishkin, Di Du, Leona A Martin, Eric Yin, Susan B Rempe, Sergei Sukharev, Marina Konopleva, John N Weinstein, Philip L Lorenzi
Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia. Molecular cancer therapeutics 18 (9) (2019)
Thomas D Horvath, Wai Kin Chan, Michael A Pontikos, Leona A Martin, Di Du, Lin Tan, Marina Konopleva, John N Weinstein, Philip L Lorenzi
Assessment of l-Asparaginase Pharmacodynamics in Mouse Models of Cancer. Metabolites 9 (1) (2019)
Jessica M Molkentine, Tara N Fujimoto, Thomas D Horvath, Aaron J Grossberg, Carolina J Garcia Garcia, Amit Deorukhkar, Marimar de la Cruz Bonilla, Daniel Lin, Errol L G Samuel, Wai Kin Chan, Philip L Lorenzi, Helen Piwnica-Worms, Robert Dantzer, James M Tour, Kathryn A Mason, Cullen M Taniguchi
Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation. Scientific reports 9 (1) (2019)
Yoko Tabe, Philip L Lorenzi, Marina Y Konopleva
Amino acid metabolism in hematologic malignancies and the era of targeted therapy. Blood 134 (13) (2019)
Limo Chen, Lixia Diao, Yongbin Yang, Xiaohui Yi, B Leticia Rodriguez, Yanli Li, Pamela A Villalobos, Tina Cascone, Xi Liu, Lin Tan, Philip L Lorenzi, Anfei Huang, Qiang Zhao, Di Peng, Jared J Fradette, David H Peng, Christin Ungewiss, Jonathon Roybal, Pan Tong, Junna Oba, Ferdinandos Skoulidis, Weiyi Peng, Brett W Carter, Carl M Gay, Youhong Fan, Caleb A Class, Jingfen Zhu, Jaime Rodriguez-Canales, Masanori Kawakami, Lauren Averett Byers, Scott E Woodman, Vassiliki A Papadimitrakopoulou, Ethan Dmitrovsky, Jing Wang, Stephen E Ullrich, Ignacio I Wistuba, John V Heymach, F Xiao-Feng Qin, Don L Gibbons
CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade. Cancer discovery 8 (9) (2018)
Lorenzo Federico, Zechen Chong, Dong Zhang, Daniel J McGrail, Wei Zhao, Kang Jin Jeong, Christopher P Vellano, Zhenlin Ju, Mihai Gagea, Shuying Liu, Shreya Mitra, Jennifer B Dennison, Philip L Lorenzi, Robert Cardnell, Lixia Diao, Jing Wang, Yiling Lu, Lauren A Byers, Charles M Perou, Shiaw-Yih Lin, Gordon B Mills
A murine preclinical syngeneic transplantation model for breast cancer precision medicine. Science advances 3 (4) (2017)
Wai Kin Chan, Philip L Lorenzi, Andriy Anishkin, Preeti Purwaha, David M Rogers, Sergei Sukharev, Susan B Rempe, John N Weinstein
The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells. Blood 123 (23) (2014)