Michael A Jakupec (Michael Jakupec)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 42

Top Topics

Liquid Chromatography

Oxidative Stress

Top Venues

Dalton transactions (Cambridge, England : 2003)

Inorganic chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

This page only lists publications with an associated author ORCID identifier.

Publications

Vivien Pósa, Anja Federa, Klaudia Cseh, Dominik Wenisch, Gabriella Spengler, Nóra V May, Norbert Lihi, Gergely Ferenc Samu, Michael A Jakupec, Bernhard K Keppler, Christian R Kowol, Éva A Enyedy
A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions. Inorganic chemistry 63 (5) (2024)
Weerasak Songoen, Dominik Wenisch, Michael A Jakupec, Witthawat Phanchai, Siriphan Sukkhaeng, Lothar Brecker, Johann Schinnerl, Sorachat Tharamak, Wanchai Pluempanupat
Flavan-Benzofurans from Artocarpus lacucha : Their Intracellular Antioxidant Activity and Molecular Docking to Glutathione Reductase. ACS omega 9 (31) (2024)
Paul Getreuer, Laura Marretta, Emine Toyoglu, Orsolya Dömötör, Michaela Hejl, Alexander Roller, Klaudia Cseh, Anton A Legin, Michael A Jakupec, Giampaolo Barone, Alessio Terenzi, Bernhard K Keppler, Wolfgang Kandioller
Investigating the anticancer potential of 4-phenylthiazole derived Ru(II) and Os(II) metalacycles. Dalton transactions (Cambridge, England : 2003) (2024)
Vivien Pósa, Anja Federa, Klaudia Cseh, Dominik Wenisch, Gabriella Spengler, Nóra V May, Norbert Lihi, Gergely Ferenc Samu, Michael A Jakupec, Bernhard K Keppler, Christian R Kowol, Éva A Enyedy
A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions. Inorganic chemistry (2024)
Vivien Pósa, Anja Federa, Klaudia Cseh, Dominik Wenisch, Gabriella Spengler, Nóra V May, Norbert Lihi, Gergely Ferenc Samu, Michael A Jakupec, Bernhard K Keppler, Christian R Kowol, Éva A Enyedy
A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions. Inorganic chemistry 63 (5) (2024)
Paul Getreuer, Laura Marretta, Emine Toyoglu, Orsolya Dömötör, Michaela Hejl, Alexander Roller, Klaudia Cseh, Anton A Legin, Michael A Jakupec, Giampaolo Barone, Alessio Terenzi, Bernhard K Keppler, Wolfgang Kandioller
Investigating the anticancer potential of 4-phenylthiazole derived Ru(II) and Os(II) metalacycles. Dalton transactions (Cambridge, England : 2003) 53 (12) (2024)
Vivien Pósa, Anja Federa, Klaudia Cseh, Dominik Wenisch, Gabriella Spengler, Nóra V May, Norbert Lihi, Gergely Ferenc Samu, Michael A Jakupec, Bernhard K Keppler, Christian R Kowol, Éva A Enyedy
A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions. Inorganic chemistry 63 (5) (2024)
Weerasak Songoen, Dominik Wenisch, Michael A Jakupec, Witthawat Phanchai, Siriphan Sukkhaeng, Lothar Brecker, Johann Schinnerl, Sorachat Tharamak, Wanchai Pluempanupat
Flavan-Benzofurans from Artocarpus lacucha : Their Intracellular Antioxidant Activity and Molecular Docking to Glutathione Reductase. ACS omega 9 (31) (2024)
Paul Getreuer, Laura Marretta, Emine Toyoglu, Orsolya Dömötör, Michaela Hejl, Alexander Roller, Klaudia Cseh, Anton A Legin, Michael A Jakupec, Giampaolo Barone, Alessio Terenzi, Bernhard K Keppler, Wolfgang Kandioller
Investigating the anticancer potential of 4-phenylthiazole derived Ru(II) and Os(II) metalacycles. Dalton transactions (Cambridge, England : 2003) 53 (12) (2024)
Vivien Pósa, Anja Federa, Klaudia Cseh, Dominik Wenisch, Gabriella Spengler, Nóra V May, Norbert Lihi, Gergely Ferenc Samu, Michael A Jakupec, Bernhard K Keppler, Christian R Kowol, Éva A Enyedy
A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions. Inorganic chemistry 63 (5) (2024)
Klaudia Cseh, Iker Berasaluce, Valentin Fuchs, Alexandra Banc, Andreas Schweikert, Alexander Roller, Michaela Hejl, Debora Wernitznig, Gunda Koellensperger, Michael A Jakupec, Wolfgang Kandioller, Michael S Malarek, Bernhard K Keppler
Anticancer Tungstenocenes with a Diverse Set of ( O,O -), ( O , S -) and ( O , N -) Chelates-A Detailed Biological Study Using an Improved Evaluation via 3D Spheroid Models. Pharmaceutics 15 (7) (2023)
Thomas Maier, Judith Wutschitz, Natalie Gajic, Michaela Hejl, Klaudia Cseh, Sebastian Mai, Michael A Jakupec, Mathea Sophia Galanski, Bernhard K Keppler
Not the usual suspect - an unexpected organometallic product during the synthesis of cytotoxic platinum(II) complexes. Dalton transactions (Cambridge, England : 2003) (2023)
Yvonne Lerchbammer-Kreith, Nadine S Sommerfeld, Klaudia Cseh, Xian Weng-Jiang, Uchechukwu Odunze, Andreas G Schätzlein, Ijeoma F Uchegbu, Mathea S Galanski, Michael A Jakupec, Bernhard K Keppler
Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform. Pharmaceutics 15 (4) (2023)
Yvonne Lerchbammer-Kreith, Nadine S Sommerfeld, Klaudia Cseh, Xian Weng-Jiang, Uchechukwu Odunze, Andreas G Schätzlein, Ijeoma F Uchegbu, Mathea S Galanski, Michael A Jakupec, Bernhard K Keppler
Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform. Pharmaceutics 15 (4) (2023)
Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D Mellor, David G Workman, Michael A Jakupec, Andreas G Schätzlein, Ijeoma F Uchegbu, Mathea Sophia Galanski, Bernhard K Keppler
Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents-A Novel Polymer Formulation for Anticancer Therapy. Pharmaceuticals (Basel, Switzerland) 16 (7) (2023)
Yvonne Lerchbammer-Kreith, Nadine S Sommerfeld, Klaudia Cseh, Xian Weng-Jiang, Uchechukwu Odunze, Andreas G Schätzlein, Ijeoma F Uchegbu, Mathea S Galanski, Michael A Jakupec, Bernhard K Keppler
Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform. Pharmaceutics 15 (4) (2023)
Yvonne Lerchbammer-Kreith, Michaela Hejl, Petra Vician, Michael A Jakupec, Walter Berger, Mathea S Galanski, Bernhard K Keppler
Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes-A More Selective Anticancer Treatment? Pharmaceutics 15 (5) (2023)
Yvonne Lerchbammer-Kreith, Nadine S Sommerfeld, Klaudia Cseh, Xian Weng-Jiang, Uchechukwu Odunze, Andreas G Schätzlein, Ijeoma F Uchegbu, Mathea S Galanski, Michael A Jakupec, Bernhard K Keppler
Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform. Pharmaceutics 15 (4) (2023)
Xiao Liu, Dominik Wenisch, Marie-Christin Barth, Klaudia Cseh, Christian R Kowol, Michael A Jakupec, Dan Gibson, Bernhard K Keppler, Wolfgang Weigand
Novel oxaliplatin(IV) complexes conjugated with ligands bearing pendant 1,2-dithiolane/1,2-diselenolane/cyclopentyl motifs. Dalton transactions (Cambridge, England : 2003) 51 (44) (2022)
Xiao Liu, Marie-Christin Barth, Klaudia Cseh, Christian R Kowol, Michael A Jakupec, Bernhard K Keppler, Dan Gibson, Wolfgang Weigand
Oxoplatin-Based Pt(IV) Lipoate Complexes and Their Biological Activity. Chemistry & biodiversity 19 (10) (2022)
Klaudia Cseh, Heiko Geisler, Kristina Stanojkovska, Julia Westermayr, Philipp Brunmayr, Dominik Wenisch, Natalie Gajic, Michaela Hejl, Martin Schaier, Gunda Koellensperger, Michael A Jakupec, Philipp Marquetand, Wolfgang Kandioller
Arene Variation of Highly Cytotoxic Tridentate Naphthoquinone-Based Ruthenium(II) Complexes and In-Depth In Vitro Studies. Pharmaceutics 14 (11) (2022)
Heiko Geisler, Sophia Harringer, Dominik Wenisch, Richard Urban, Michael A Jakupec, Wolfgang Kandioller, Bernhard K Keppler
Systematic Study on the Cytotoxic Potency of Commonly Used Dimeric Metal Precursors in Human Cancer Cell Lines. ChemistryOpen 11 (7) (2022)
Valentin Fuchs, Klaudia Cseh, Michaela Hejl, Petra Vician, Benjamin Neuditschko, Samuel M Meier-Menches, Lukas Janker, Andrea Bileck, Natalie Gajic, Julia Kronberger, Martin Schaier, Sophie Neumayer, Gunda Köllensperger, Christopher Gerner, Walter Berger, Michael A Jakupec, Michael S Malarek, Bernhard K Keppler
Highly Cytotoxic Molybdenocenes with Strong Metabolic Effects Inhibit Tumour Growth in Mice. Chemistry (Weinheim an der Bergstrasse, Germany) (2022)
Irena Pashkunova-Martic, Rositsa Kukeva, Radostina K Stoyanova, Ivayla Pantcheva, Petar Dorkov, Joachim Friske, Michaela Hejl, Michael A Jakupec, Mariam Hohagen, Anton A Legin, Werner Lubitz, Bernhard K Keppler, Thomas H Helbich, Juliana Ivanova
Novel Salinomycin-Based Paramagnetic Complexes-First Evaluation of Their Potential Theranostic Properties. Pharmaceutics 14 (11) (2022)
Heiko Geisler, Julia Westermayr, Klaudia Cseh, Dominik Wenisch, Valentin Fuchs, Sophia Harringer, Sarah Plutzar, Natalie Gajic, Michaela Hejl, Michael A Jakupec, Philipp Marquetand, Wolfgang Kandioller
Tridentate 3-Substituted Naphthoquinone Ruthenium Arene Complexes: Synthesis, Characterization, Aqueous Behavior, and Theoretical and Biological Studies. Inorganic chemistry 60 (13) (2021)
Lisa Kater, Benjamin Kater, Michael A Jakupec, Bernhard K Keppler, Aram Prokop
KP772 overcomes multiple drug resistance in malignant lymphoma and leukemia cells in vitro by inducing Bcl-2-independent apoptosis and upregulation of Harakiri. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 26 (8) (2021)
Weerasak Songoen, Witthawat Phanchai, Lothar Brecker, Dominik Wenisch, Michael A Jakupec, Wanchai Pluempanupat, Johann Schinnerl
Highly Aromatic Flavan-3-ol Derivatives from Palaeotropical Artocarpus lacucha Buch.-Ham Possess Radical Scavenging and Antiproliferative Properties. Molecules (Basel, Switzerland) 26 (4) (2021)
Sophia Harringer, Debora Wernitznig, Natalie Gajic, Andreas Diridl, Dominik Wenisch, Michaela Hejl, Michael A Jakupec, Sarah Theiner, Gunda Koellensperger, Wolfgang Kandioller, Bernhard K Keppler
Introducing N-, P-, and S-donor leaving groups: an investigation of the chemical and biological properties of ruthenium, rhodium and iridium thiopyridone piano stool complexes. Dalton transactions (Cambridge, England : 2003) 49 (44) (2021)
Mate Rusz, Giorgia Del Favero, Yasin El Abiead, Christopher Gerner, Bernhard K Keppler, Michael A Jakupec, Gunda Koellensperger
Morpho-metabotyping the oxidative stress response. Scientific reports 11 (1) (2021)
Helena A Herrmann, Mate Rusz, Dina Baier, Michael A Jakupec, Bernhard K Keppler, Walter Berger, Gunda Koellensperger, Juergen Zanghellini
Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer. Cancers 13 (16) (2021)
Tian Ma, Peng Yang, Inga Dammann, Zheng-Guo Lin, Ali S Mougharbel, Ming-Xing Li, Florin Adǎscǎliţei, Raluca Mitea, Cristian Silvestru, Candice Thorstenson, Matthias S Ullrich, Klaudia Cseh, Michael A Jakupec, Bernhard K Keppler, Manuela Donalisio, Roberta Cavalli, David Lembo, Ulrich Kortz
Tetra-(p-tolyl)antimony(III)-Containing Heteropolytungstates, [{(p-tolyl)SbIII}4(A-α-XW9O34)2]n- (X = P, As, or Ge): Synthesis, Structure, and Study of Antibacterial and Antitumor Activity. Inorganic chemistry 59 (5) (2020)
Anton A Legin, Arno Schintlmeister, Nadine S Sommerfeld, Margret Eckhard, Sarah Theiner, Siegfried Reipert, Daniel Strohhofer, Michael A Jakupec, Mathea Sophia Galanski, Michael Wagner, Bernhard K Keppler
Nano-scale imaging of dual stable isotope labeled oxaliplatin in human colon cancer cells reveals the nucleolus as a putative node for therapeutic effect. Nanoscale advances 3 (1) (2020)
Maria S Legina, Juan J Nogueira, Wolfgang Kandioller, Michael A Jakupec, Leticia González, Bernhard K Keppler
Biological evaluation of novel thiomaltol-based organometallic complexes as topoisomerase IIα inhibitors. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 25 (3) (2020)
Sophia Harringer, Barbara Happl, Marius Ozenil, Caroline Kast, Michaela Hejl, Debora Wernitznig, Anton A Legin, Andreas Schweikert, Natalie Gajic, Alexander Roller, Gunda Koellensperger, Michael A Jakupec, Wolfgang Kandioller, Bernhard K Keppler
Synthesis, Modification, and Biological Evaluation of a Library of Novel Water-Soluble Thiopyridone-Based Organometallic Complexes and Their Unexpected (Biological) Behavior. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (24) (2020)
Iker Berasaluce, Klaudia Cseh, Alexander Roller, Michaela Hejl, Petra Heffeter, Walter Berger, Michael A Jakupec, Wolfgang Kandioller, Michael S Malarek, Bernhard K Keppler
The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo-A Comparison of O,O-, S,O-, and N,N-Chelate Effects. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (10) (2019)
Stephan Mokesch, Daniela Schwarz, Michaela Hejl, Matthias H M Klose, Alexander Roller, Michael A Jakupec, Wolfgang Kandioller, Bernhard K Keppler
Fine-Tuning the Activation Mode of an 1,3-Indandione-Based Ruthenium(II)-Cymene Half-Sandwich Complex by Variation of Its Leaving Group. Molecules (Basel, Switzerland) 24 (13) (2019)
Mate Rusz, Evelyn Rampler, Bernhard K Keppler, Michael A Jakupec, Gunda Koellensperger
Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids. Metabolites 9 (12) (2019)
Gabriella Tamasi, Antonello Merlino, Federica Scaletti, Petra Heffeter, Anton A Legin, Michael A Jakupec, Walter Berger, Luigi Messori, Bernhard K Keppler, Renzo Cini
{Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo. Dalton transactions (Cambridge, England : 2003) 46 (9) (2018)
Carmen M Hackl, Beatrix Schoenhacker-Alte, Matthias H M Klose, Helena Henke, Maria S Legina, Michael A Jakupec, Walter Berger, Bernhard K Keppler, Oliver Brüggemann, Ian Teasdale, Petra Heffeter, Wolfgang Kandioller
Synthesis and in vivo anticancer evaluation of poly(organo)phosphazene-based metallodrug conjugates. Dalton transactions (Cambridge, England : 2003) 46 (36) (2017)
Samuel M Meier-Menches, Dominique Kreutz, Lilli Winter, Matthias H M Klose, Klaudia Cseh, Tamara Weiss, Andrea Bileck, Beatrix Alte, Johanna C Mader, Samir Jana, Annesha Chatterjee, Arindam Bhattacharyya, Michaela Hejl, Michael A Jakupec, Petra Heffeter, Walter Berger, Christian G Hartinger, Bernhard K Keppler, Gerhard Wiche, Christopher Gerner
An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin. Angewandte Chemie (International ed. in English) 56 (28) (2017)
Simone Göschl, Ekaterina Schreiber-Brynzak, Verena Pichler, Klaudia Cseh, Petra Heffeter, Ute Jungwirth, Michael A Jakupec, Walter Berger, Bernhard K Keppler
Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models. Metallomics : integrated biometal science 9 (3) (2017)
Lea S Flocke, Robert Trondl, Michael A Jakupec, Bernhard K Keppler
Molecular mode of action of NKP-1339 - a clinically investigated ruthenium-based drug - involves ER- and ROS-related effects in colon carcinoma cell lines. Investigational new drugs 34 (3) (2016)