Michael J Betenbaugh (Michael Betenbaugh)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 31

Top Topics

Endoplasmic Reticulum Stress

Antibiotic Resistance Genes

Top Venues

Biotechnology and bioengineering

NPJ systems biology and applications

Plant physiology

Biotechnology journal

This page only lists publications with an associated author ORCID identifier.

Publications

Chien-Ting Li, Richard Eng, Cristal Zuniga, Kai-Wen Huang, Yiqun Chen, Karsten Zengler, Michael J Betenbaugh
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control. NPJ systems biology and applications 9 (1) (2023)
Harnish Mukesh Naik, Swetha Kumar, Jayanth Venkatarama Reddy, Jacqueline E Gonzalez, Brian O McConnell, Venkata Gayatri Dhara, Tiexin Wang, Marcella Yu, Maciek Antoniewicz, Michael J Betenbaugh
Chemical inhibitors of hexokinase-2 enzyme reduce lactate accumulation, alter glycosylation processing, and produce altered glycoforms in CHO cell cultures. Biotechnology and bioengineering (2023)
Chien-Ting Li, Richard Eng, Cristal Zuniga, Kai-Wen Huang, Yiqun Chen, Karsten Zengler, Michael J Betenbaugh
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control. NPJ systems biology and applications 9 (1) (2023)
Pranay Ladiwala, Venkata Gayatri Dhara, Jackson Jenkins, Bingyu Kuang, Duc Hoang, Seongkyu Yoon, Michael J Betenbaugh
Addressing amino acid-derived inhibitory metabolites and enhancing CHO cell culture performance through DOE-guided media modifications. Biotechnology and bioengineering (2023)
Harnish Mukesh Naik, Swetha Kumar, Jayanth Venkatarama Reddy, Jacqueline E Gonzalez, Brian O McConnell, Venkata Gayatri Dhara, Tiexin Wang, Marcella Yu, Maciek R Antoniewicz, Michael J Betenbaugh
Chemical inhibitors of hexokinase-2 enzyme reduce lactate accumulation, alter glycosylation processing, and produce altered glycoforms in CHO cell cultures. Biotechnology and bioengineering (2023)
Pranay Ladiwala, Venkata Gayatri Dhara, Jackson Jenkins, Bingyu Kuang, Duc Hoang, Seongkyu Yoon, Michael J Betenbaugh
Addressing amino acid-derived inhibitory metabolites and enhancing CHO cell culture performance through DOE-guided media modifications. Biotechnology and bioengineering (2023)
Chien-Ting Li, Richard Eng, Cristal Zuniga, Kai-Wen Huang, Yiqun Chen, Karsten Zengler, Michael J Betenbaugh
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control. NPJ systems biology and applications 9 (1) (2023)
Venkata Gayatri Dhara, Swetha Kumar, Lauren DeVine, Harnish Mukesh Naik, Robert Norman Cole, Abbie J More, Eduardo Catchon Lau, Michael J Betenbaugh
Cottonseed hydrolysate supplementation alters metabolic and proteomics responses in Chinese Hamster Ovary cell cultures. Biotechnology journal (2023)
Pranay Ladiwala, Venkata Gayatri Dhara, Jackson Jenkins, Bingyu Kuang, Duc Hoang, Seongkyu Yoon, Michael J Betenbaugh
Addressing amino acid-derived inhibitory metabolites and enhancing CHO cell culture performance through DOE-guided media modifications. Biotechnology and bioengineering (2023)
Qiang Fu, Yong Suk Lee, Erica A Green, Yongdan Wang, So Young Park, Ashli Polanco, Kelvin H Lee, Michael J Betenbaugh, David McNally, Seongkyu Yoon
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing. Biotechnology and bioengineering (2023)
Meiping Chang, Amit Kumar, Swetha Kumar, Steven C Huhn, Winston Timp, Michael J Betenbaugh, Zhimei Du
Epigenetic comparison of CHO hosts and clones reveals divergent methylation and transcription patterns across lineages. Biotechnology and bioengineering 119 (4) (2022)
Sarah A Sacco, Angela M Tuckowski, Irina Trenary, Lauren Kraft, Michael J Betenbaugh, Jamey D Young, Kevin D Smith
Attenuation of glutamine synthetase selection marker improves product titer and reduces glutamine overflow in Chinese hamster ovary cells. Biotechnology and bioengineering 119 (7) (2022)
Swetha Kumar, Amit Kumar, Steven C Huhn, Lauren DeVine, Robert N Cole, Zhimei Du, Michael J Betenbaugh
A proteomics approach to decipher a sticky CHO situation. Biotechnology and bioengineering 119 (8) (2022)
Lauren T Cordova, Hussain Dahodwala, Kathryn S Elliott, Jongyoun Baik, Daniel C Odenewelder, Douglas Nmagu, Bradley A Skelton, Lisa Uy, Stephanie R Klaubert, Benjamin F Synoground, Dylan G Chitwood, Venkata Gayatri Dhara, Harnish Mukesh Naik, Caitlin S Morris, Seongkyu Yoon, Michael J Betenbaugh, Jonathan Coffman, Frank Swartzwelder, Michael Gilmeister, Sarah W Harcum, Kelvin H Lee
Generation of reference cell lines, media, and a process platform for CHO cell biomanufacturing. Biotechnology and bioengineering (2022)
Kevin S McFarland, Jie Zhu, Pritam Sinharoy, Michael J Betenbaugh, Michael W Handlogten
Engineering redox sensors into CHO cells enables near-real-time quantification of intracellular redox in bioprocesses. Biotechnology and bioengineering 119 (6) (2022)
Meiping Chang, Steven C Huhn, Luke Nelson, Michael J Betenbaugh, Zhimei Du
Significant impact of mTORC1 and ATF4 pathways in CHO cell recombinant protein production induced by CDK4/6 inhibitor. Biotechnology and bioengineering 119 (5) (2022)
Qiong Wang, Tiexin Wang, Roushu Zhang, Shuang Yang, Kevin S McFarland, Cheng-Yu Chung, Hongpeng Jia, Lai-Xi Wang, John F Cipollo, Michael J Betenbaugh
The interplay of protein engineering and glycoengineering to fine-tune antibody glycosylation and its impact on effector functions. Biotechnology and bioengineering 119 (1) (2021)
Yiqun Chen, Xiao Liu, Ji Young L Anderson, Harnish Mukesh Naik, Venkata Gayatri Dhara, Xiaolu Chen, Glenn A Harris, Michael J Betenbaugh
A genome-scale nutrient minimization forecast algorithm for controlling essential amino acid levels in CHO cell cultures. Biotechnology and bioengineering (2021)
Brian James Kirsch, Sandra V Bennun, Adam Mendez, Amy S Johnson, Hongxia Wang, Haibo Qiu, Ning Li, Shawn M Lawrence, Hanne Bak, Michael J Betenbaugh
Metabolic Analysis of the Asparagine and Glutamine Dynamics in an Industrial CHO Fed-Batch Process. Biotechnology and bioengineering (2021)
Timothy A Whitehead, Scott Banta, William E Bentley, Michael J Betenbaugh, Christina Chan, Douglas S Clark, Corinne A Hoesli, Michael C Jewett, Beth Junker, Mattheos A G Koffas, Rashmi Kshirsagar, Amanda Lewis, Chien-Ting Li, Costas D Maranas, E Terry Papoutsakis, Kristala L J Prather, Steffen Schaffer, Laura Segatori, Ian Wheeldon
The importance and future of biochemical engineering. Biotechnology and bioengineering 117 (8) (2020)
Cheng-Yu Chung, Qiong Wang, Shuang Yang, Sandra Chough, Younji Seo, John F Cipollo, Joseph P Balthasar, Michael J Betenbaugh
The impact of sialylation linkage-type on the pharmacokinetics of recombinant butyrylcholinesterases. Biotechnology and bioengineering 117 (1) (2019)
Qiong Wang, Ganglong Yang, Tiexin Wang, Weiming Yang, Michael J Betenbaugh, Hui Zhang
Characterization of intact glycopeptides reveals the impact of culture media on site-specific glycosylation of EPO-Fc fusion protein generated by CHO-GS cells. Biotechnology and bioengineering 116 (9) (2019)
Oliver Rupp, Madolyn L MacDonald, Shangzhong Li, Heena Dhiman, Shawn Polson, Sven Griep, Kelley Heffner, Inmaculada Hernandez, Karina Brinkrolf, Vaibhav Jadhav, Mojtaba Samoudi, Haiping Hao, Brewster Kingham, Alexander Goesmann, Michael J Betenbaugh, Nathan E Lewis, Nicole Borth, Kelvin H Lee
A reference genome of the Chinese hamster based on a hybrid assembly strategy. Biotechnology and bioengineering 115 (8) (2018)
Bojiao Yin, Qiong Wang, Cheng-Yu Chung, Xiaozhi Ren, Rahul Bhattacharya, Kevin J Yarema, Michael J Betenbaugh
Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells. Biotechnology and bioengineering 115 (6) (2018)
Qiong Wang, Cheng-Yu Chung, Sandra Chough, Michael J Betenbaugh
Antibody glycoengineering strategies in mammalian cells. Biotechnology and bioengineering 115 (6) (2018)
Sabine Vcelar, Vaibhav Jadhav, Michael Melcher, Norbert Auer, Astrid Hrdina, Rebecca Sagmeister, Kelley Heffner, Anja Puklowski, Michael J Betenbaugh, Till Wenger, Friedrich Leisch, Martina Baumann, Nicole Borth
Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting. Biotechnology and bioengineering 115 (1) (2018)
Cristal Zuñiga, Jennifer Levering, Maciek R Antoniewicz, Michael T Guarnieri, Michael J Betenbaugh, Karsten Zengler
Predicting Dynamic Metabolic Demands in the Photosynthetic Eukaryote Chlorella vulgaris. Plant physiology 176 (1) (2017)
Bojiao Yin, Qiong Wang, Cheng-Yu Chung, Rahul Bhattacharya, Xiaozhi Ren, Juechun Tang, Kevin J Yarema, Michael J Betenbaugh
A novel sugar analog enhances sialic acid production and biotherapeutic sialylation in CHO cells. Biotechnology and bioengineering 114 (8) (2017)
Qiong Wang, Charles H Chen, Cheng-Yu Chung, Joseph Priola, Jeffrey H Chu, Juechun Tang, Martin B Ulmschneider, Michael J Betenbaugh
Proline-Rich Chaperones Are Compared Computationally and Experimentally for Their Abilities to Facilitate Recombinant Butyrylcholinesterase Tetramerization in CHO Cells. Biotechnology journal 13 (3) (2017)
Cheng-Yu Chung, Qiong Wang, Shuang Yang, Sean A Ponce, Brian J Kirsch, Hui Zhang, Michael J Betenbaugh
Combinatorial genome and protein engineering yields monoclonal antibodies with hypergalactosylation from CHO cells. Biotechnology and bioengineering 114 (12) (2017)
Cristal Zuñiga, Chien-Ting Li, Tyler Huelsman, Jennifer Levering, Daniel C Zielinski, Brian O McConnell, Christopher P Long, Eric P Knoshaug, Michael T Guarnieri, Maciek R Antoniewicz, Michael J Betenbaugh, Karsten Zengler
Genome-Scale Metabolic Model for the Green Alga Chlorella vulgaris UTEX 395 Accurately Predicts Phenotypes under Autotrophic, Heterotrophic, and Mixotrophic Growth Conditions. Plant physiology 172 (1) (2016)