Kelvin H Lee (Kelvin Lee)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 36

Top Venues

Biotechnology and bioengineering

Biotechnology journal

Biotechnology progress

Molecular pharmaceutics

University of Delaware

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Delaware

United States

Director :: Delaware Biotechnology Institute

University of Delaware

United States

Gore Professor :: Chemical and Biomolecular Engineering

Cornell University

United States

Director :: Biotechnology Institute

Cornell University

United States

Asst/Assoc/Full Professor :: Chemical Engineering

Publications

Alana C Szkodny, Kelvin H Lee
A systemic approach to identifying sequence frameworks that decrease mAb production in a transient Chinese hamster ovary cell expression system. Biotechnology progress (2024)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing. Biotechnology and bioengineering (2024)
Carolyn M Remsburg, Kalin D Konrad, Michael D Testa, Nadezda Stepicheva, Kelvin H Lee, Leila H Choe, Shawn W Polson, Jaysheel Bhavsar, Hongzhan Huang, Jia L Song
miR-31-mediated local translation at the mitotic spindle is important for early development. Development (Cambridge, England) 151 (17) (2024)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing. Biotechnology and bioengineering 121 (4) (2024)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing. Biotechnology and bioengineering 121 (4) (2024)
Lauren T Cordova, Hussain Dahodwala, Rebecca Cooley, Kelvin H Lee
Prediction of CHO cell line stability using expression of DNA repair genes. Biotechnology journal (2023)
Carolyn Remsburg, Kalin Konrad, Nadezda Stepicheva, Michael Testa, Kelvin H Lee, Leila Choe, Shawn Polson, Jaysheel Bhavsar, Hongzhan Huang, Jia Song
miR-31-mediated local translation at the mitotic spindle is important for early development. Research square (2023)
Young Hoon Oh, Kerri M Mendola, Leila H Choe, Lie Min, R Ashton Lavoie, Sobhana Alekhya Sripada, Taufika Islam Williams, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing. Biotechnology and bioengineering (2023)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing. Biotechnology and bioengineering 120 (4) (2023)
William Hilliard, Kelvin H Lee
A compendium of stable hotspots in the CHO genome. Biotechnology and bioengineering (2023)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing. Biotechnology and bioengineering 120 (4) (2023)
Nathaniel K Hamaker, Kelvin H Lee
High-efficiency and multilocus targeted integration in CHO cells using CRISPR-mediated donor nicking and DNA repair inhibitors. Biotechnology and bioengineering (2023)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing. Biotechnology and bioengineering 120 (4) (2023)
Qiang Fu, Yong Suk Lee, Erica A Green, Yongdan Wang, So Young Park, Ashli Polanco, Kelvin H Lee, Michael J Betenbaugh, David McNally, Seongkyu Yoon
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing. Biotechnology and bioengineering (2023)
Eugene Schaefer, John Balchunas, Timothy Charlebois, John Erickson, Roger Hart, Sandeep B Kedia, Kelvin H Lee
Driving adoption of new technologies in biopharmaceutical manufacturing. Biotechnology and bioengineering (2023)
Chase E Herman, Lie Min, Leila H Choe, Ronald W Maurer, Xuankuo Xu, Sanchayita Ghose, Kelvin H Lee, Abraham M Lenhoff
Analytical characterization of host-cell-protein-rich aggregates in monoclonal antibody solutions. Biotechnology progress (2023)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing. Biotechnology and bioengineering 120 (4) (2023)
Sandeep B Kedia, Jeffrey C Baker, Ruben G Carbonell, Kelvin H Lee, Christopher J Roberts, John Erickson, John E Schiel, Kelley Rogers, Eugene Schaefer, Stefanie Pluschkell
Biomanufacturing readiness levels [BRL]-A shared vocabulary for biopharmaceutical technology development and commercialization. Biotechnology and bioengineering 119 (12) (2022)
Nathaniel K Hamaker, Lie Min, Kelvin H Lee
Comprehensive assessment of host cell protein expression after extended culture and bioreactor production of CHO cell lines. Biotechnology and bioengineering 119 (8) (2022)
Lauren T Cordova, Hussain Dahodwala, Kathryn S Elliott, Jongyoun Baik, Daniel C Odenewelder, Douglas Nmagu, Bradley A Skelton, Lisa Uy, Stephanie R Klaubert, Benjamin F Synoground, Dylan G Chitwood, Venkata Gayatri Dhara, Harnish Mukesh Naik, Caitlin S Morris, Seongkyu Yoon, Michael J Betenbaugh, Jonathan Coffman, Frank Swartzwelder, Michael Gilmeister, Sarah W Harcum, Kelvin H Lee
Generation of reference cell lines, media, and a process platform for CHO cell biomanufacturing. Biotechnology and bioengineering (2022)
Natraj Ram, Jeff Johnson, Hiren Ardeshna, Joseph Camire, Ryan Campbell, Doan Chau, Sam Gardner, Kevin Gibson, Joey Norikane, Paul Randolph, Kelly Smith, Katherine Stafford, Rachel Swamy, Shana Usery, Kelvin H Lee
Evaluation of the design, development, and performance of a mass-flow based, open-source buffer manufacturing system. PDA journal of pharmaceutical science and technology (2022)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing. Biotechnology and bioengineering (2022)
Young Hoon Oh, Matthew L Becker, Kerri M Mendola, Leila H Choe, Lie Min, Kelvin H Lee, Yinges Yigzaw, Alexander Seay, Jerome Bill, Xuanwen Li, David J Roush, Steven M Cramer, Stefano Menegatti, Abraham M Lenhoff
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing. Biotechnology and bioengineering (2022)
Madolyn L MacDonald, Kelvin H Lee
EvalDNA: a machine learning-based tool for the comprehensive evaluation of mammalian genome assembly quality. BMC bioinformatics 22 (1) (2021)
John Erickson, Jeffrey Baker, Shawn Barrett, Ciaran Brady, Mark Brower, Ruben Carbonell, Tim Charlebois, Jonathan Coffman, Lisa Connell-Crowley, Michael Coolbaugh, Eric Fallon, Eric Garr, Christopher Gillespie, Roger Hart, Allison Haug, Gregg Nyberg, Michael Phillips, David Pollard, Maen Qadan, Irina Ramos, Kelley Rogers, Gene Schaefer, Jason Walther, Kelvin H Lee
End-to-end collaboration to transform biopharmaceutical development and manufacturing. Biotechnology and bioengineering 118 (9) (2021)
Jong Youn Baik, Hye-Jin Han, Kelvin H Lee
DNA Double-Strand Breaks Affect Chromosomal Rearrangements during Methotrexate-Mediated Gene Amplification in Chinese Hamster Ovary Cells. Pharmaceutics 13 (3) (2021)
Madolyn L MacDonald, Shawn W Polson, Kelvin H Lee
k-mer-Based Metagenomics Tools Provide a Fast and Sensitive Approach for the Detection of Viral Contaminants in Biopharmaceutical and Vaccine Manufacturing Applications Using Next-Generation Sequencing. mSphere 6 (2) (2021)
William Hilliard, Madolyn L MacDonald, Kelvin H Lee
Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome. Biotechnology and bioengineering 117 (8) (2020)
John S Ruano-Salguero, Kelvin H Lee
Adsorptive-Mediated Endocytosis of Sulfo-Cy5-Labeled IgG Causes Aberrant IgG Processing by Brain Endothelial-Like Cells. Molecular pharmaceutics 17 (11) (2020)
John S Ruano-Salguero, Kelvin H Lee
Antibody transcytosis across brain endothelial-like cells occurs nonspecifically and independent of FcRn. Scientific reports 10 (1) (2020)
Yu Luo, Robert J Lovelett, J Vincent Price, Devesh Radhakrishnan, Kristopher Barnthouse, Ping Hu, Eugene Schaefer, John Cunningham, Kelvin H Lee, Raghunath B Shivappa, Babatunde A Ogunnaike
Modeling the Effect of Amino Acids and Copper on Monoclonal Antibody Productivity and Glycosylation: A Modular Approach. Biotechnology journal 16 (2) (2020)
Nathaniel K Hamaker, Kelvin H Lee
A Site-Specific Integration Reporter System That Enables Rapid Evaluation of CRISPR/Cas9-Mediated Genome Editing Strategies in CHO Cells. Biotechnology journal 15 (8) (2020)
Jennifer L Mantle, Kelvin H Lee
Immunoglobulin G transport increases in an in vitro blood-brain barrier model with amyloid-β and with neuroinflammatory cytokines. Biotechnology and bioengineering 116 (7) (2019)
John S Ruano-Salguero, Kelvin H Lee
Efflux Pump Substrates Shuttled to Cytosolic or Vesicular Compartments Exhibit Different Permeability in a Quantitative Human Blood-Brain Barrier Model. Molecular pharmaceutics 15 (11) (2018)
Matthew S Rehmann, Kelsi M Skeens, Prathamesh M Kharkar, Eden M Ford, Emanual Maverakis, Kelvin H Lee, April M Kloxin
Tuning and Predicting Mesh Size and Protein Release from Step Growth Hydrogels. Biomacromolecules 18 (10) (2017)
Amalie T Levy, Kelvin H Lee, Thomas E Hanson
Chlorobaculum tepidum Modulates Amino Acid Composition in Response to Energy Availability, as Revealed by a Systematic Exploration of the Energy Landscape of Phototrophic Sulfur Oxidation. Applied and environmental microbiology 82 (21) (2016)

Kelvin H Lee.css-eqlu8i{font-size:small;padding-left:4px;} (Kelvin Lee)

Publication Activity (10 Years)

Top Topics

Top Venues

Kelvin H Lee (Kelvin Lee)