Michael Ohh

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 16

Top Venues

Scientific reports

Nature communications

Communications biology

Proceedings of the National Academy of Sciences of the United States of America

University of Toronto

University of British Columbia (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto

Canada

Professor :: Laboratory Medicine & Pathobiology

Dana-Farber Cancer Institute

United States

Postdoctoral Fellow :: Molecular Oncology

Education History

University of British Columbia

Canada

PHD :: Medical Genetics

Publications

Fraser G Ferens, Cassandra C Taber, Sarah Stuart, Mia Hubert, Daniel Tarade, Jeffrey E Lee, Michael Ohh
Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome. Communications biology 7 (1) (2024)
Sarah Stuart, Daniel Tarade, Michael Ohh
Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage. Scientific reports 14 (1) (2024)
Wenguang He, Geneviève M C Gasmi-Seabrook, Mitsuhiko Ikura, Jeffrey E Lee, Michael Ohh
Time-resolved NMR detection of prolyl-hydroxylation in intrinsically disordered region of HIF-1α. Proceedings of the National Academy of Sciences of the United States of America 121 (37) (2024)
Fraser G Ferens, Cassandra C Taber, Sarah Stuart, Mia Hubert, Daniel Tarade, Jeffrey E Lee, Michael Ohh
Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome. Communications biology 7 (1) (2024)
Fraser G Ferens, Cassandra C Taber, Sarah Stuart, Mia Hubert, Daniel Tarade, Jeffrey E Lee, Michael Ohh
Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome. Communications biology 7 (1) (2024)
Sarah Stuart, Daniel Tarade, Michael Ohh
Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage. Scientific reports 14 (1) (2024)
Sarah Stuart, Daniel Tarade, Michael Ohh
Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage. Scientific reports 14 (1) (2024)
Sarah Stuart, Daniel Tarade, Michael Ohh
Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage. Scientific reports 14 (1) (2024)
Ivette Valencia-Sama, Lynn Kee, Gabriella Christopher, Michael Ohh, Mehdi Layeghifard, Adam Shlien, Madeline N Hayes, Meredith S Irwin
SHP2 inhibition with TNO155 increases efficacy and overcomes resistance of ALK inhibitors in neuroblastoma. Cancer research communications (2023)
Kenneth K Y Ting, Pei Yu, Riley Dow, Eric Floro, Hisham M Ibrahim, Corey A Scipione, Sharon J Hyduk, Chanele K Polenz, Olga Zaslaver, Peer W F Karmaus, Michael B Fessler, Hannes L Röst, Michael Ohh, Sue Tsai, Daniel A Winer, Minna Woo, Jonathan V Rocheleau, Jenny Jongstra-Bilen, Myron I Cybulsky
Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway. Journal of immunology (Baltimore, Md. : 1950) (2023)
Michael Ohh, Cassandra C Taber, Fraser G Ferens, Daniel Tarade
Hypoxia-inducible factor underlies von Hippel-Lindau disease stigmata. eLife 11 (2022)
Teklab Gebregiworgis, Yoshihito Kano, Jonathan St-Germain, Nikolina Radulovich, Molly L Udaskin, Ahmet Mentes, Richard Huang, Betty P K Poon, Wenguang He, Ivette Valencia-Sama, Claire M Robinson, Melissa Huestis, Jinmin Miao, Jen Jen Yeh, Zhong-Yin Zhang, Meredith S Irwin, Jeffrey E Lee, Ming Sound Tsao, Brian Raught, Christopher B Marshall, Michael Ohh, Mitsuhiko Ikura
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. Nature communications 12 (1) (2021)
Karan Joshua Abraham, Negin Khosraviani, Janet N Y Chan, Aparna Gorthi, Anas Samman, Dorothy Y Zhao, Miling Wang, Michael Bokros, Elva Vidya, Lauren Anne Todd, Roxanne Oshidari, Violena Pietrobon, Parasvi S Patel, Arash Algouneh, Rajat Singhania, Yupeng Liu, V Talya Yerlici, Daniel D De Carvalho, Michael Ohh, Brendan C Dickson, Razq Hakem, Jack F Greenblatt, Stephen Lee, Alexander J R Bishop, Karim Mekhail
Nucleolar RNA polymerase II drives ribosome biogenesis. Nature 585 (7824) (2020)
Yoshihito Kano, Teklab Gebregiworgis, Christopher B Marshall, Nikolina Radulovich, Betty P K Poon, Jonathan St-Germain, Jonathan D Cook, Ivette Valencia-Sama, Benjamin M M Grant, Silvia Gabriela Herrera, Jinmin Miao, Brian Raught, Meredith S Irwin, Jeffrey E Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming Sound Tsao, Mitsuhiko Ikura, Michael Ohh
Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation. Nature communications 10 (1) (2019)
Daniel Tarade, Jeffrey E Lee, Michael Ohh
Evolution of metazoan oxygen-sensing involved a conserved divergence of VHL affinity for HIF1α and HIF2α. Nature communications 10 (1) (2019)
Daniel Tarade, Claire M Robinson, Jeffrey E Lee, Michael Ohh
HIF-2α-pVHL complex reveals broad genotype-phenotype correlations in HIF-2α-driven disease. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Michael Ohh