Mitsuhiko Ikura

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 12

Top Topics

Metastatic Colorectal Cancer

Signaling Pathway

Molecular Dynamics

Top Venues

Protein science : a publication of the Protein Society

Science signaling

Nature chemical biology

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Ningdi F Liu, Masahiro Enomoto, Christopher B Marshall, Mitsuhiko Ikura
Reconstitution and characterization of BRAF in complex with 14-3-3 and KRAS4B on nanodiscs. Protein science : a publication of the Protein Society 33 (6) (2024)
Ningdi F Liu, Masahiro Enomoto, Christopher B Marshall, Mitsuhiko Ikura
Reconstitution and characterization of BRAF in complex with 14-3-3 and KRAS4B on nanodiscs. Protein science : a publication of the Protein Society 33 (6) (2024)
Ningdi F Liu, Masahiro Enomoto, Christopher B Marshall, Mitsuhiko Ikura
Reconstitution and characterization of BRAF in complex with 14-3-3 and KRAS4B on nanodiscs. Protein science : a publication of the Protein Society 33 (6) (2024)
Christopher B Marshall, Mitsuhiko Ikura
Hitting the hotspots. Nature chemical biology 18 (6) (2022)
Teklab Gebregiworgis, Yoshihito Kano, Jonathan St-Germain, Nikolina Radulovich, Molly L Udaskin, Ahmet Mentes, Richard Huang, Betty P K Poon, Wenguang He, Ivette Valencia-Sama, Claire M Robinson, Melissa Huestis, Jinmin Miao, Jen Jen Yeh, Zhong-Yin Zhang, Meredith S Irwin, Jeffrey E Lee, Ming Sound Tsao, Brian Raught, Christopher B Marshall, Michael Ohh, Mitsuhiko Ikura
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. Nature communications 12 (1) (2021)
Ki-Young Lee, Masahiro Enomoto, Teklab Gebregiworgis, Geneviève M C Gasmi-Seabrook, Mitsuhiko Ikura, Christopher B Marshall
Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization. Chemical science 12 (38) (2021)
Benjamin M M Grant, Masahiro Enomoto, Sung-In Back, Ki-Young Lee, Teklab Gebregiworgis, Noboru Ishiyama, Mitsuhiko Ikura, Christopher B Marshall
Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety. Science signaling 13 (625) (2020)
Zhenhao Fang, Ki-Young Lee, Ku-Geng Huo, Geneviève Gasmi-Seabrook, Le Zheng, Nadeem Moghal, Ming-Sound Tsao, Mitsuhiko Ikura, Christopher B Marshall
Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane. Proceedings of the National Academy of Sciences of the United States of America 117 (22) (2020)
Ki-Young Lee, Zhenhao Fang, Masahiro Enomoto, Genevieve Gasmi-Seabrook, Le Zheng, Shohei Koide, Mitsuhiko Ikura, Christopher B Marshall
Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement. Angewandte Chemie (International ed. in English) 59 (27) (2020)
Christopher B Marshall, Fenneke KleinJan, Teklab Gebregiworgis, Ki-Young Lee, Zhenhao Fang, Ben J Eves, Ningdi F Liu, Geneviève M C Gasmi-Seabrook, Masahiro Enomoto, Mitsuhiko Ikura
NMR in integrated biophysical drug discovery for RAS: past, present, and future. Journal of biomolecular NMR 74 (10-11) (2020)
Teklab Gebregiworgis, Christopher B Marshall, Tadateru Nishikawa, Nikolina Radulovich, María-José Sandí, Zhenhao Fang, Robert Rottapel, Ming-Sound Tsao, Mitsuhiko Ikura
Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids. Journal of the American Chemical Society 140 (13) (2018)
Tadateru Nishikawa, Noboru Ishiyama, Feng Wang, Mitsuhiko Ikura
Backbone resonance assignments of the F-actin binding domain of mouse αN-catenin. Biomolecular NMR assignments 11 (1) (2016)