Muralidhar L Hegde (Muralidhar Hegde)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 38

Top Venues

Research square

Molecular brain

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Houston Methodist Research Institute

CFTRI, University of Mysore, India and Max Planck Institute, Germany (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Houston Methodist Research Institute Oct 26 2016

United States

Associate Professor :: Radiation Oncology

Weill Medical College of Cornell University Oct 26 2016

United States

Associate Professor :: Neuroscience

Weill Cornell Medical College Sep 03 2013 - Oct 26 2016

United States

Assistant Professor :: Neuroscience

Houston Methodist Neurological Institute Sep 03 2013 - Oct 26 2016

United States

Assistant Professor

University of Texas Medical Branch at Galveston

United States

Research Assistant Professor :: Biochemistry and Molecular Biology

Education History

CFTRI, University of Mysore, India and Max Planck Institute, Germany

India

PHD

Publications

Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M Hegde, Vincent Provasek, Vikas H Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E Tomkinson, Dale J Hamilton, Ludo Van Den Bosch, Muralidhar L Hegde
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature communications 15 (1) (2024)
Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M Hegde, Vincent Provasek, Vikas H Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E Tomkinson, Dale J Hamilton, Ludo Van Den Bosch, Muralidhar L Hegde
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature communications 15 (1) (2024)
Vincent E Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L Hegde
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. Molecular brain 17 (1) (2024)
Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M Hegde, Vincent Provasek, Vikas H Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E Tomkinson, Dale J Hamilton, Ludo Van Den Bosch, Muralidhar L Hegde
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature communications 15 (1) (2024)
Joy Mitra, Prakash Dharmalingam, Manohar Kodavati, Erika N Guerrero, K S Rao, Ralph M Garruto, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence. Research square (2024)
Vincent E Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L Hegde
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. Molecular brain 17 (1) (2024)
Muralidhar L Hegde, Vikas Rao, Velmarini Vasquez, Manohar Kodavati, Joy Mitra, Vincent Provasek, Anh Vo, Thomas Andrew Kent, Paul Derry, Andrei Mikheve, Robert Rostomily, Philip Horner, James M Tour, Gavin Britz, Anton Liopo
Hemin-Induced Transient Senescence via DNA Damage Response as Potential Neuroprotective Mechanism during Brain Hemorrhage. Research square (2024)
Vincent E Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L Hegde
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. Molecular brain 17 (1) (2024)
Joy Mitra, Prakash Dharmalingam, Manohar M Kodavati, Erika N Guerrero, K S Rao, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, in ammation, and neuronal senescence. Research square (2024)
Joy Mitra, Prakash Dharmalingam, Manohar M Kodavati, Erika N Guerrero, K S Rao, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence. Research square (2024)
Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M Hegde, Vincent Provasek, Vikas H Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E Tomkinson, Dale J Hamilton, Ludo Van Den Bosch, Muralidhar L Hegde
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature communications 15 (1) (2024)
Joy Mitra, Prakash Dharmalingam, Manohar M Kodavati, Erika N Guerrero, K S Rao, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, in ammation, and neuronal senescence. Research square (2024)
Vincent E Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L Hegde
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. Molecular brain 17 (1) (2024)
Joy Mitra, Prakash Dharmalingam, Manohar M Kodavati, Erika N Guerrero, K S Rao, Ralph Garruto, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence. Research square (2024)
Muralidhar L Hegde, Vikas Rao, Velmarini Vasquez, Manohar Kodavati, Joy Mitra, Vincent Provasek, Anh Vo, Thomas Andrew Kent, Paul Derry, Andrei Mikheve, Robert Rostomily, Philip Horner, James M Tour, Gavin Britz, Anton Liopo
Hemin-Induced Transient Senescence via DNA Damage Response as Potential Neuroprotective Mechanism during Brain Hemorrhage. Research square (2024)
Joy Mitra, Prakash Dharmalingam, Manohar Kodavati, Erika N Guerrero, K S Rao, Ralph M Garruto, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence. Research square (2024)
Vikas H Maloji Rao, Velmarini Vasquez, Manohar Kodavati, Joy Mitra, Vincent Provasek, Anh Vo, Anton Liopo, Paul J Derry, Andrei Mikheve, Robert C Rostomily, Philip J Horner, James M Tour, Gavin W Britz, Thomas A Kent, Muralidhar L Hegde
Hemin-Induced Transient Senescence Via DNA Damage Response: A Neuroprotective Mechanism Against Ferroptosis in Intracerebral Hemorrhage. Research square (2024)
Muralidhar L Hegde, Velmarini Vasquez, Manohar Kodavati, Joy Mitra, Indira Vendula, Dale Hamilton, Ralph Garruto, K S Rao
Mitochondria-Targeted Oligomeric α-Synuclein Induces TOM40 Degradation and Mitochondrial Dysfunction in Parkinson's Disease and Parkinsonism-Dementia of Guam. Research square (2024)
Vincent E Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L Hegde
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. Molecular brain 17 (1) (2024)
Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M Hegde, Vincent Provasek, Vikas H Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E Tomkinson, Dale J Hamilton, Ludo Van Den Bosch, Muralidhar L Hegde
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. Nature communications 15 (1) (2024)
Muralidhar L Hegde, Velmarini Vasquez, Manohar Kodavati, Joy Mitra, Indira Vendula, Dale Hamilton, Ralph Garruto, K S Rao
Mitochondria-Targeted Oligomeric α-Synuclein Induces TOM40 Degradation and Mitochondrial Dysfunction in Parkinson's Disease and Parkinsonism-Dementia of Guam. Research square (2024)
Vincent E Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L Hegde
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner. Molecular brain 17 (1) (2024)
Joy Mitra, Prakash Dharmalingam, Manohar M Kodavati, Erika N Guerrero, K S Rao, Muralidhar L Hegde
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence. Research square (2024)
Muralidhar L Hegde, Kodavati Manohar, Haibo Wang, Wenting Gao, Joy Mitra, Pavana M Hegde, Vincent Provasek, Vikas Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E Tomkinson, Ludo Van Den Bosch, Dale J Hamilton
FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in FUS-Linked Neurodegeneration. Research square (2023)
Vincent E Provasek, Joy Mitra, Vikas H Malojirao, Muralidhar L Hegde
DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders. International journal of molecular sciences 23 (9) (2022)
Bradley J Eckelmann, Albino Bacolla, Haibo Wang, Zu Ye, Erika N Guerrero, Wei Jiang, Randa El-Zein, Muralidhar L Hegde, Alan E Tomkinson, John A Tainer, Sankar Mitra
XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells. NAR cancer 2 (3) (2020)
Anirban Chakraborty, Nisha Tapryal, Tatiana Venkova, Joy Mitra, Velmarini Vasquez, Altaf H Sarker, Sara Duarte-Silva, Weihan Huai, Tetsuo Ashizawa, Gourisankar Ghosh, Patrícia Maciel, Partha S Sarkar, Muralidhar L Hegde, Xu Chen, Tapas K Hazra
Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 117 (14) (2020)
Manohar Kodavati, Haibo Wang, Muralidhar L Hegde
Altered Mitochondrial Dynamics in Motor Neuron Disease: An Emerging Perspective. Cells 9 (4) (2020)
Prakash Dharmalingam, Girish Talakatta, Joy Mitra, Haibo Wang, Paul J Derry, Lizanne Greer Nilewski, Emily A McHugh, Roderic H Fabian, Kimberly Mendoza, Velmarini Vasquez, Pavana M Hegde, Eugenia Kakadiaris, Trenton Roy, Istvan Boldogh, Venkatesh L Hegde, Sankar Mitra, James M Tour, Thomas A Kent, Muralidhar L Hegde
Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle. ACS nano 14 (3) (2020)
Shiladitya Sengupta, Haibo Wang, Chunying Yang, Bartosz Szczesny, Muralidhar L Hegde, Sankar Mitra
Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription. Proceedings of the National Academy of Sciences of the United States of America 117 (36) (2020)
Joy Mitra, Pavana M Hegde, Muralidhar L Hegde
Loss of endosomal recycling factor RAB11 coupled with complex regulation of MAPK/ERK/AKT signaling in postmortem spinal cord specimens of sporadic amyotrophic lateral sclerosis patients. Molecular brain 12 (1) (2019)
Haibo Wang, Suganya Rangaswamy, Manohar Kodavati, Joy Mitra, Wenting Guo, Erika N Guerrero, Ludo Van Den Bosch, Muralidhar L Hegde
RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease. Molecular brain 12 (1) (2019)
Haibo Wang, Muralidhar L Hegde
New Mechanisms of DNA Repair Defects in Fused in Sarcoma-Associated Neurodegeneration: Stage Set for DNA Repair-Based Therapeutics? Journal of experimental neuroscience 13 (2019)
Joy Mitra, Muralidhar L Hegde
A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis. Journal of experimental neuroscience 13 (2019)
Deborah Doens, Mario E Valdés-Tresanco, Velmarini Vasquez, Maria Beatriz Carreira, Yila De La Guardia, David E Stephens, Viet D Nguyen, Vu T Nguyen, Jianhua Gu, Muralidhar L Hegde, Oleg V Larionov, Pedro A Valiente, Ricardo Lleonart, Patricia L Fernández
Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer's Disease. ACS chemical neuroscience 10 (10) (2019)
Johant Lakey-Beitia, D Jagadeesh Kumar, Muralidhar L Hegde, Jagannatha Rao Kosagisharaf
Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis. International journal of molecular sciences 20 (22) (2019)
Haibo Wang, Wenting Guo, Joy Mitra, Pavana M Hegde, Tijs Vandoorne, Bradley J Eckelmann, Sankar Mitra, Alan E Tomkinson, Ludo Van Den Bosch, Muralidhar L Hegde
Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis. Nature communications 9 (1) (2018)
Lang Pan, Bing Zhu, Wenjing Hao, Xianlu Zeng, Spiros A Vlahopoulos, Tapas K Hazra, Muralidhar L Hegde, Zsolt Radak, Attila Bacsi, Allan R Brasier, Xueqing Ba, Istvan Boldogh
Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression. The Journal of biological chemistry 291 (49) (2016)

Muralidhar L Hegde.css-eqlu8i{font-size:small;padding-left:4px;} (Muralidhar Hegde)

Publication Activity (10 Years)

Top Topics

Top Venues

Muralidhar L Hegde (Muralidhar Hegde)