Nabil G Seidah

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Venues

Molecular and cellular biology

Cells

Viruses

The FEBS journal

IRCM

Gerogetown University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

IRCM

Canada

Director of the laboratory :: Biochemical Neuroendocrinology

Education History

Gerogetown University Sep 01 1969 - Dec 11 1973

United States

PHD :: Chemistry

Cairo University Sep 01 1966 - Jul 01 1969

Egypt

BSC :: Chemistry

Publications

Sebastian Hendrix, Josephine M E Tan, Klevis Ndoj, Jenina Kingma, Masoud Valiloo, Lobke F Zijlstra, Roelof Ottenhoff, Nabil G Seidah, Anke Loregger, Daniel L Kober, Noam Zelcer
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Molecular and cellular biology 44 (4) (2024)
Sepideh Mikaeeli, Ali Ben Djoudi Ouadda, Alexandra Evagelidis, Rachid Essalmani, Oscar Henrique Pereira Ramos, Carole Fruchart Gaillard, Nabil G Seidah
Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C. Cells 13 (10) (2024)
Sebastian Hendrix, Josephine M E Tan, Klevis Ndoj, Jenina Kingma, Masoud Valiloo, Lobke F Zijlstra, Roelof Ottenhoff, Nabil G Seidah, Anke Loregger, Daniel L Kober, Noam Zelcer
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Molecular and cellular biology 44 (4) (2024)
Sebastian Hendrix, Josephine M E Tan, Klevis Ndoj, Jenina Kingma, Masoud Valiloo, Lobke F Zijlstra, Roelof Ottenhoff, Nabil G Seidah, Anke Loregger, Daniel L Kober, Noam Zelcer
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Molecular and cellular biology 44 (4) (2024)
Sebastian Hendrix, Josephine M E Tan, Klevis Ndoj, Jenina Kingma, Masoud Valiloo, Lobke F Zijlstra, Roelof Ottenhoff, Nabil G Seidah, Anke Loregger, Daniel L Kober, Noam Zelcer
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Molecular and cellular biology 44 (4) (2024)
Sepideh Mikaeeli, Ali Ben Djoudi Ouadda, Alexandra Evagelidis, Rachid Essalmani, Oscar Henrique Pereira Ramos, Carole Fruchart Gaillard, Nabil G Seidah
Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C. Cells 13 (10) (2024)
Sebastian Hendrix, Josephine M E Tan, Klevis Ndoj, Jenina Kingma, Masoud Valiloo, Lobke F Zijlstra, Roelof Ottenhoff, Nabil G Seidah, Anke Loregger, Daniel L Kober, Noam Zelcer
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Molecular and cellular biology (2024)
Sebastian Hendrix, Josephine M E Tan, Klevis Ndoj, Jenina Kingma, Masoud Valiloo, Lobke F Zijlstra, Roelof Ottenhoff, Nabil G Seidah, Anke Loregger, Daniel L Kober, Noam Zelcer
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Molecular and cellular biology 44 (4) (2024)
Rachid Essalmani, Ursula Andréo, Alexandra Evagelidis, Maïlys Le Dévéhat, Oscar Henrique Pereira Ramos, Carole Fruchart Gaillard, Delia Susan-Resiga, Éric A Cohen, Nabil G Seidah
SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2. Viruses 15 (2) (2023)
Rachid Essalmani, Ursula Andréo, Alexandra Evagelidis, Maïlys Le Dévéhat, Oscar Henrique Pereira Ramos, Carole Fruchart Gaillard, Delia Susan-Resiga, Éric A Cohen, Nabil G Seidah
SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2. Viruses 15 (2) (2023)
Rachid Essalmani, Ursula Andréo, Alexandra Evagelidis, Maïlys Le Dévéhat, Oscar Henrique Pereira Ramos, Carole Fruchart Gaillard, Delia Susan-Resiga, Éric A Cohen, Nabil G Seidah
SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2. Viruses 15 (2) (2023)
Malak Alannan, Nabil G Seidah, Aksam J Merched
PCSK9 in Liver Cancers at the Crossroads between Lipid Metabolism and Immunity. Cells 11 (24) (2022)
Jessie R Davis, Xiao Wang, Isaac P Witte, Tony P Huang, Jonathan M Levy, Aditya Raguram, Samagya Banskota, Nabil G Seidah, Kiran Musunuru, David R Liu
Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors. Nature biomedical engineering 6 (11) (2022)
Mahshid Malakootian, Parisa Naeli, Seyed Javad Mowla, Nabil G Seidah
Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators. Metabolites 12 (7) (2022)
Nabil G Seidah, Annik Prat
The Multifaceted Biology of PCSK9. Endocrine reviews 43 (3) (2022)
Malak Alannan, Nabil G Seidah, Aksam J Merched
PCSK9 in Liver Cancers at the Crossroads between Lipid Metabolism and Immunity. Cells 11 (24) (2022)
Malak Alannan, Nabil G Seidah, Aksam J Merched
PCSK9 in Liver Cancers at the Crossroads between Lipid Metabolism and Immunity. Cells 11 (24) (2022)
Rachid Essalmani, Jaspreet Jain, Delia Susan-Resiga, Ursula Andréo, Alexandra Evagelidis, Rabeb Mouna Derbali, David N Huynh, Frédéric Dallaire, Mélanie Laporte, Adrien Delpal, Priscila Sutto-Ortiz, Bruno Coutard, Claudine Mapa, Keith Wilcoxen, Etienne Decroly, Tram Nq Pham, Éric A Cohen, Nabil G Seidah
Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity. Journal of virology 96 (8) (2022)
Nabil G Seidah, Damien Garçon
Expanding Biology of PCSK9: Roles in Atherosclerosis and Beyond. Current atherosclerosis reports 24 (10) (2022)
Malak Alannan, Nabil G Seidah, Aksam J Merched
PCSK9 in Liver Cancers at the Crossroads between Lipid Metabolism and Immunity. Cells 11 (24) (2022)
Rachid Essalmani, Jaspreet Jain, Delia Susan-Resiga, Ursula Andréo, Alexandra Evagelidis, Rabeb Mouna Derbali, David N Huynh, Frédéric Dallaire, Mélanie Laporte, Adrien Delpal, Priscila Sutto-Ortiz, Bruno Coutard, Claudine Mapa, Keith Wilcoxen, Etienne Decroly, Tram N Q Pham, Éric A Cohen, Nabil G Seidah
Erratum for Essalmani et al., "Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity". Journal of virology 96 (13) (2022)
Nabil G Seidah, Antonella Pasquato, Ursula Andréo
How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread? Viruses 13 (7) (2021)
Aouatef Bellamine, Tram N Q Pham, Jaspreet Jain, Jacob Wilson, Kazım Şahin, Frederic Dallaire, Nabil G Seidah, Shane Durkee, Katarina Radošević, Éric A Cohen
L-Carnitine Tartrate Downregulates the ACE2 Receptor and Limits SARS-CoV-2 Infection. Nutrients 13 (4) (2021)
Stéphanie Duval, Afnan Abu-Thuraia, Islam E Elkholi, Rui Chen, Deeptee Seebun, Janice Mayne, Jean-François Coté, Daniel Figeys, Nabil G Seidah
Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression. Cell death & disease 11 (8) (2020)
Yahya Ashraf, Stéphanie Duval, Vatsal Sachan, Rachid Essalmani, Delia Susan-Resiga, Anna Roubtsova, Josée Hamelin, Stefan Gerhardy, Daniel Kirchhofer, Vincent S Tagliabracci, Annik Prat, Robert Scott Kiss, Nabil G Seidah
Proprotein convertase 7 (PCSK7) reduces apoA-V levels. The FEBS journal 287 (16) (2020)
Vatsal Sachan, Robert Lodge, Koichiro Mihara, Josée Hamelin, Christopher Power, Benjamin B Gelman, Morley D Hollenberg, Éric A Cohen, Nabil G Seidah
HIV-induced neuroinflammation: impact of PAR1 and PAR2 processing by Furin. Cell death and differentiation 26 (10) (2019)
Michael Chong, Grace Yoon, Delia Susan-Resiga, Ann Chamberland, David Cheillan, Guillaume Paré, Nabil G Seidah
Hypolipidaemia among patients with PMM2-CDG is associated with low circulating PCSK9 levels: a case report followed by observational and experimental studies. Journal of medical genetics 57 (1) (2019)
Sepideh Mikaeeli, Delia Susan-Resiga, Emmanuelle Girard, Ali Ben Djoudi Ouadda, Robert Day, Stefan Prost, Nabil G Seidah
Functional analysis of natural PCSK9 mutants in modern and archaic humans. The FEBS journal 287 (3) (2019)
Nabil G Seidah
Insights into a PCSK9 structural groove: a harbinger of new drugs to reduce LDL-cholesterol. Nature structural & molecular biology 24 (10) (2019)
Rachid Essalmani, Delia Susan-Resiga, Johann Guillemot, Woojin Kim, Vatsal Sachan, Zuhier Awan, Ann Chamberland, Marie-Claude Asselin, Kévin Ly, Roxane Desjardins, Robert Day, Annik Prat, Nabil G Seidah
Thrombin activation of protein C requires prior processing by a liver proprotein convertase. The Journal of biological chemistry 292 (25) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Nabil G Seidah