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Nancy A Speck (Nancy Speck)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 13

Top Venues

Blood

Genes & development

bioRxiv : the preprint server for biology

Development (Cambridge, England)

University of Pennsylvania

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania

United States

Professor and Chair :: Cell and Developmental Biology

Publications

Alexandra U Zezulin, Daniel Yen, Darwin Ye, Elizabeth D Howell, Erica Bresciani, Jamie Diemer, Jian-Gang Ren, Mohd Hafiz Ahmad, Lucio H Castilla, Ivo P Touw, Andy J Minn, Wei Tong, P Paul Liu, Kai Tan, Wenbao Yu, Nancy A Speck
RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils. Genes & development (2023)
Alexandra U Zezulin, Darwin Ye, Elizabeth Howell, Daniel Yen, Erica Bresciani, Jamie Diemer, Jian-Gang Ren, Mohd Hafiz Ahmad, Lucio H Castilla, Ivo P Touw, Andy J Minn, Wei Tong, P Paul Liu, Kai Tan, Wenbao Yu, Nancy A Speck
RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils. bioRxiv : the preprint server for biology (2023)
Madison B Wilken, Gennadiy Fonar, Catriana Nations, Giulia Pavani, Victor Tsao, James Garifallou, Joanna Tober, Laura Bennett, Jean Ann Maguire, Alyssa Gagne, Nkemdilim Okoli, Paul Gadue, Stella T Chou, Nancy A Speck, Deborah L French, Christopher Stephen Thom
Tropomyosin 1 deficiency facilitates cell state transitions to enhance hemogenic endothelial cell specification during hematopoiesis. bioRxiv : the preprint server for biology (2023)
Yiqing Yang, Melanie D Mumau, Joanna Tober, Qin Zhu, Laura F Bennett, Courtney Hong, Derek C Sung, Thomas Keller, Yasin Uzun, Peng Gao, Swapnil Shewale, Mei Chen, Jisheng Yang, Xiaowen Chen, Steven A Thomas, Kai Tan, Nancy A Speck, Mark L Kahn
Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis. Blood 139 (19) (2022)
Nancy A Speck
A Pernicious Cycle Affecting Premalignant Stem Cells. The New England journal of medicine 386 (6) (2022)
Laura F Bennett, Melanie D Mumau, Yan Li, Nancy A Speck
MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryo. Development (Cambridge, England) 149 (8) (2022)
Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael V Gonzalez, James P Garifallou, Hakon H Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy A Speck, Deborah L French, Paul Gadue, Mortimer Poncz
RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells. Blood 137 (19) (2021)
Elizabeth D Howell, Amanda D Yzaguirre, Peng Gao, Raphael Lis, Bing He, Melike Lakadamyali, Shahin Rafii, Kai Tan, Nancy A Speck
Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes. Genes & development 35 (21-22) (2021)
Jingmei Hsu, Hsuan-Ting Huang, Chung-Tsai Lee, Avik Choudhuri, Nicola K Wilson, Brian J Abraham, Victoria Moignard, Iwo Kucinski, Shuqian Yu, R Katherine Hyde, Joanna Tober, Xiongwei Cai, Yan Li, Yalin Guo, Song Yang, Michael Superdock, Eirini Trompouki, Fernando J Calero-Nieto, Alireza Ghamari, Jing Jiang, Peng Gao, Long Gao, Vy Nguyen, Anne L Robertson, Ellen M Durand, Katie L Kathrein, Iannis Aifantis, Scott A Gerber, Wei Tong, Kai Tan, Alan B Cantor, Yi Zhou, P Paul Liu, Richard A Young, Berthold Göttgens, Nancy A Speck, Leonard I Zon
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America 117 (38) (2020)
Elizabeth D Howell, Nancy A Speck
Forks in the road to the first hematopoietic stem cells. Cell research 30 (6) (2020)
Amanda D Yzaguirre, Elizabeth D Howell, Yan Li, Zijing Liu, Nancy A Speck
Runx1 is sufficient for blood cell formation from non-hemogenic endothelial cells in vivo only during early embryogenesis. Development (Cambridge, England) 145 (2) (2018)
Yan Li, Long Gao, Brandon Hadland, Kai Tan, Nancy A Speck
CD27 marks murine embryonic hematopoietic stem cells and type II prehematopoietic stem cells. Blood 130 (3) (2017)
Joanna Tober, Marijke M W Maijenburg, Yan Li, Long Gao, Brandon K Hadland, Peng Gao, Kodai Minoura, Irwin D Bernstein, Kai Tan, Nancy A Speck
Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1. The Journal of experimental medicine 215 (2) (2017)

Nancy A Speck.css-eqlu8i{font-size:small;padding-left:4px;} (Nancy Speck)

Publication Activity (10 Years)

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Nancy A Speck (Nancy Speck)