Leonard I Zon (Leonard Zon, L I Zon)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 66

Top Topics

Transcription Factor

Histone Deacetylase

Top Venues

Science (New York, N.Y.)

Proceedings of the National Academy of Sciences of the United States of America

The Journal of experimental medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Haley R Noonan, Alexandra M Thornock, Julia Barbano, Michael E Xifaras, Chloe S Baron, Song Yang, Katherine Koczirka, Alicia M McConnell, Leonard I Zon
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma. eLife 13 (2024)
Cecilia Pessoa Rodrigues, Joseph M Collins, Song P Yang, Catherine Martinez, Ji Wook Kim, Chhiring Lama, Anna S Nam, Clemens Alt, Charles P Lin, Leonard I Zon
Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells. Science (New York, N.Y.) 385 (6714) (2024)
WenYe Liu, YuYan Ding, Zheng Shen, Cong Xu, William Yi, Ding Wang, Yi Zhou, Leonard I Zon, Jing-Xia Liu
BF170 hydrochloride enhances the emergence of hematopoietic stem and progenitor cells. Development (Cambridge, England) 151 (13) (2024)
Haley R Noonan, Alexandra M Thornock, Julia Barbano, Michael E Xifaras, Chloe S Baron, Song Yang, Katherine Koczirka, Alicia M McConnell, Leonard I Zon
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma. eLife 13 (2024)
Anne L Robertson, Lu Yue, Avik Choudhuri, Caroline Kubaczka, Samuel J Wattrus, Joseph Mandelbaum, Serine Avagyan, Song Yang, Rebecca J Freeman, Victoria Chan, Megan C Blair, George Q Daley, Leonard I Zon
Hematopoietic stem cell division is governed by distinct RUNX1 binding partners. bioRxiv : the preprint server for biology (2024)
Haley R Noonan, Alexandra M Thornock, Julia Barbano, Michael E Xifaras, Chloe S Baron, Song Yang, Katherine Koczirka, Alicia M McConnell, Leonard I Zon
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma. eLife 13 (2024)
Haley R Noonan, Alexandra M Thornock, Julia Barbano, Michael E Xifaras, Chloe S Baron, Song Yang, Katherine Koczirka, Alicia M McConnell, Leonard I Zon
A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma. eLife 13 (2024)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Audrey Sporrij, Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M Fast, Margot E Manning, Jodi D Weiss, Michelle Koh, Song Yang, Robert E Kingston, Michael Yevgeniy Tolstorukov, Hans Clevers, Leonard I Zon
PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Jiarui Song, Anne R Gooding, Wayne O Hemphill, Brittney D Love, Anne Robertson, Liqi Yao, Leonard I Zon, Trista E North, Vignesh Kasinath, Thomas R Cech
Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science (New York, N.Y.) 381 (6664) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Jesús García-Castillo, Francisca Alcaraz-Pérez, Elena Martínez-Balsalobre, Diana García-Moreno, Marlies P Rossmann, Miriam Fernández-Lajarín, Manuel Bernabé, Ana Belen Perez Oliva, Virginia C Rodríguez-Cortez, Clara Bueno, Isaac Adatto, Suneet Agarwal, Pablo Menéndez, Leonard I Zon, Victoriano Mulero, Maria Luisa Cayuela
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America 118 (32) (2022)
Jeffrey K Mito, Margaret C Weber, Alexandra F Corbin, George F Murphy, Leonard I Zon
Modeling Spitz melanoma in zebrafish using sequential mutagenesis. Disease models & mechanisms 15 (8) (2022)
Vijay G Sankaran, Jonathan S Weissman, Leonard I Zon
Cellular barcoding to decipher clonal dynamics in disease. Science (New York, N.Y.) 378 (6616) (2022)
Julien Ablain, Amira Al Mahi, Harriet T Rothschild, Meera Prasad, Sophie Aires, Song Yang, Maxim E Dokukin, Shuyun Xu, Michelle Dang, Igor Sokolov, Christine G Lian, Leonard I Zon
Loss of NECTIN1 triggers melanoma dissemination upon local IGF1 depletion. Nature genetics 54 (12) (2022)
Sara A Rubin, Chloé S Baron, Cecilia Pessoa Rodrigues, Madeleine Duran, Alexandra F Corbin, Song P Yang, Cole Trapnell, Leonard I Zon
Single-cell analyses reveal early thymic progenitors and pre-B cells in zebrafish. The Journal of experimental medicine 219 (9) (2022)
Samuel J Wattrus, Mackenzie L Smith, Cecilia Pessoa Rodrigues, Elliott J Hagedorn, Ji Wook Kim, Bogdan Budnik, Leonard I Zon
Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality. Science (New York, N.Y.) 377 (6613) (2022)
Marlies P Rossmann, Karen Hoi, Victoria Chan, Brian J Abraham, Song Yang, James P Mullahoo, Malvina Papanastasiou, Ying Wang, Ilaria Elia, Julie R Perlin, Elliott J Hagedorn, Sara Hetzel, Raha Weigert, Sejal Vyas, Partha P Nag, Lucas B Sullivan, Curtis R Warren, Bilguujin Dorjsuren, Eugenia Custo Greig, Isaac Adatto, Chad A Cowan, Stuart L Schreiber, Richard A Young, Alexander Meissner, Marcia C Haigis, Siegfried Hekimi, Steven A Carr, Leonard I Zon
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science (New York, N.Y.) 372 (6543) (2021)
Shuning He, Mark W Zimmerman, Hillary M Layden, Alla Berezovskaya, Julia Etchin, Megan W Martel, Grace Thurston, Chang-Bin Jing, Ellen van Rooijen, Charles K Kaufman, Scott J Rodig, Leonard I Zon, E Elizabeth Patton, Marc R Mansour, A Thomas Look
Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. Oncogene 40 (38) (2021)
Marlies P Rossmann, Sonia M Dubois, Suneet Agarwal, Leonard I Zon
Mitochondrial function in development and disease. Disease models & mechanisms 14 (6) (2021)
Audrey Sporrij, Leonard I Zon
Nucleotide stress responses in neural crest cell fate and melanoma. Cell cycle (Georgetown, Tex.) 20 (15) (2021)
Serine Avagyan, Margaret C Weber, Sai Ma, Meera Prasad, William P Mannherz, Song Yang, Jason D Buenrostro, Leonard I Zon
Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages. Blood advances 5 (13) (2021)
S Avagyan, Jonathan E Henninger, William P Mannherz, Meeta Mistry, Joon Yoon, Song P Yang, M C Weber, Jessica L Moore, Leonard I Zon
Resistance to inflammation underlies enhanced fitness in clonal hematopoiesis. Science (New York, N.Y.) 374 (6568) (2021)
Eva Maria Fast, Audrey Sporrij, Margot Manning, Edroaldo Lummertz Rocha, Song Yang, Yi Zhou, Jimin Guo, Ninib Baryawno, Nikolaos Barkas, David Scadden, Fernando Camargo, Leonard I Zon
External signals regulate continuous transcriptional states in hematopoietic stem cells. eLife 10 (2021)
Maurizio Fazio, Ellen van Rooijen, Michelle Dang, Glenn van de Hoek, Julien Ablain, Jeffrey K Mito, Song Yang, Andrew Thomas, Jonathan Michael, Tania Fabo, Rodsy Modhurima, Patrizia Pessina, Charles K Kaufman, Yi Zhou, Richard M White, Leonard I Zon
SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance. eLife 10 (2021)
Alison M Taylor, Elizabeth R Macari, Iris T Chan, Megan C Blair, Sergei Doulatov, Linda T Vo, David M Raiser, Kavitha Siva, Anindita Basak, Mehdi Pirouz, Arish N Shah, Katherine McGrath, Jessica M Humphries, Emma Stillman, Blanche P Alter, Eliezer Calo, Richard I Gregory, Vijay G Sankaran, Johan Flygare, Benjamin L Ebert, Yi Zhou, George Q Daley, Leonard I Zon
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science translational medicine 12 (566) (2021)
Alicia M McConnell, Leonard I Zon
Dissecting melanocytes to predict melanoma. Nature cell biology 23 (9) (2021)
Maurizio Fazio, Julien Ablain, Chuan Yan, David M Langenau, Leonard I Zon
Zebrafish patient avatars in cancer biology and precision cancer therapy. Nature reviews. Cancer 20 (5) (2020)
Jingmei Hsu, Hsuan-Ting Huang, Chung-Tsai Lee, Avik Choudhuri, Nicola K Wilson, Brian J Abraham, Victoria Moignard, Iwo Kucinski, Shuqian Yu, R Katherine Hyde, Joanna Tober, Xiongwei Cai, Yan Li, Yalin Guo, Song Yang, Michael Superdock, Eirini Trompouki, Fernando J Calero-Nieto, Alireza Ghamari, Jing Jiang, Peng Gao, Long Gao, Vy Nguyen, Anne L Robertson, Ellen M Durand, Katie L Kathrein, Iannis Aifantis, Scott A Gerber, Wei Tong, Kai Tan, Alan B Cantor, Yi Zhou, P Paul Liu, Richard A Young, Berthold Göttgens, Nancy A Speck, Leonard I Zon
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America 117 (38) (2020)
Jiyeon Choi, Tongwu Zhang, Andrew Vu, Julien Ablain, Matthew M Makowski, Leandro M Colli, Mai Xu, Rebecca C Hennessey, Jinhu Yin, Harriet Rothschild, Cathrin Gräwe, Michael A Kovacs, Karen M Funderburk, Myriam Brossard, John C Taylor, Bogdan Pasaniuc, Raj Chari, Stephen J Chanock, Clive J Hoggart, Florence Demenais, Jennifer H Barrett, Matthew H Law, Mark M Iles, Kai Yu, Michiel Vermeulen, Leonard I Zon, Kevin K Brown
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nature communications 11 (1) (2020)
Monica J Justice, Julija Hmeljak, Vijay G Sankaran, Merav Socolovsky, Leonard I Zon
From blood development to disease: a paradigm for clinical translation. Disease models & mechanisms 13 (1) (2020)
Maurizio Fazio, Ellen van Rooijen, Jeffrey K Mito, Rodsy Modhurima, Erika Weiskopf, Song Yang, Leonard I Zon
Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis. Pigment cell & melanoma research 34 (3) (2020)
Avik Choudhuri, Eirini Trompouki, Brian J Abraham, Leandro M Colli, Kian Hong Kock, William Mallard, Min-Lee Yang, Divya S Vinjamur, Alireza Ghamari, Audrey Sporrij, Karen Hoi, Barbara Hummel, Sonja Boatman, Victoria Chan, Sierra Tseng, Satish K Nandakumar, Song Yang, Asher Lichtig, Michael Superdock, Seraj N Grimes, Teresa V Bowman, Yi Zhou, Shinichiro Takahashi, Roby Joehanes, Alan B Cantor, Daniel E Bauer, Santhi K Ganesh, John Rinn, Paul S Albert, Martha L Bulyk, Stephen J Chanock, Richard A Young, Leonard I Zon
Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits. Nature genetics 52 (12) (2020)
Cristina Santoriello, Audrey Sporrij, Song Yang, Ryan A Flynn, Telmo Henriques, Bilguujin Dorjsuren, Eugenia Custo Greig, Wyatt McCall, Meredith E Stanhope, Maurizio Fazio, Michael Superdock, Asher Lichtig, Isaac Adatto, Brian J Abraham, Marian Kalocsay, Michael Jurynec, Yi Zhou, Karen Adelman, Eliezer Calo, Leonard I Zon
RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nature cell biology 22 (4) (2020)
Megan S Rost, Ilya Shestopalov, Yang Liu, Andy H Vo, Catherine E Richter, Sylvia M Emly, Francesca G Barrett, David L Stachura, Michael A Holinstat, Leonard I Zon, Jordan A Shavit
Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish. Blood advances 2 (23) (2019)
Samuel J Wattrus, Leonard I Zon
Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish. Blood advances 2 (21) (2019)
Leonard I Zon
Improving the visibility of developmental biology: time for induction and specification. Development (Cambridge, England) 146 (2) (2019)
Qilin Gu, Xiaojie Yang, Jie Lv, Jiaxiong Zhang, Bo Xia, Jun-Dae Kim, Ruoyu Wang, Feng Xiong, Shu Meng, Thomas P Clements, Bhavna Tandon, Daniel S Wagner, Miguel F Diaz, Pamela L Wenzel, Yury I Miller, David Traver, John P Cooke, Wenbo Li, Leonard I Zon, Kaifu Chen, Yong-Ping Bai, Longhou Fang
AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science (New York, N.Y.) 363 (6431) (2019)
Michael J Jurynec, Xiaoying Bai, Brent W Bisgrove, Haley Jackson, Alex Nechiporuk, Rebecca A S Palu, Hannah A Grunwald, Yi-Chu Su, Kazuyuki Hoshijima, H Joseph Yostl, Leonard I Zon, David Jonah Grunwald
The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development (Cambridge, England) 146 (24) (2019)
Julien Ablain, Mengshu Xu, Harriet T Rothschild, Richard C Jordan, Jeffrey K Mito, Brianne H Daniels, Caitlin F Bell, Nancy M Joseph, Hong Wu, Boris C Bastian, Leonard I Zon, Iwei Yeh
Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma. Science (New York, N.Y.) 362 (6418) (2018)
Margarita Parada-Kusz, Cristina Penaranda, Elliott J Hagedorn, Anne Clatworthy, Anil V Nair, Jonathan E Henninger, Christoph Ernst, Brian Li, Raquel Riquelme, Humberto Jijon, Eduardo J Villablanca, Leonard I Zon, Deborah Hung, Miguel L Allende
Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies. Disease models & mechanisms 11 (11) (2018)
Gene I Uenishi, Ho Sun Jung, Akhilesh Kumar, Mi Ae Park, Brandon K Hadland, Ethan McLeod, Matthew Raymond, Oleg Vladimirovich Moskvin, Catherine E Zimmerman, Derek J Theisen, Scott A Swanson, Owen J Tamplin, Leonard I Zon, James A Thomson, Irwin D Bernstein, Igor I Slukvin
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells. Nature communications 9 (1) (2018)
Moufida Ben Nasr, Sara Tezza, Francesca D'Addio, Chiara Mameli, Vera Usuelli, Anna Maestroni, Domenico Corradi, Silvana Belletti, Luca Albarello, Gabriella Becchi, Gian Poalo Fadini, Christian Schuetz, James Markmann, Clive Wasserfall, Leonard I Zon, Gian Vincenzo Zuccotti, Paolo Fiorina
PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. Science translational medicine 9 (416) (2018)
Marc R Mansour, Shuning He, Zhaodong Li, Riadh Lobbardi, Brian J Abraham, Clemens Hug, Sunniyat Rahman, Theresa E León, You-Yi Kuang, Mark W Zimmerman, Traci M Blonquist, Evisa Gjini, Alejandro Gutierrez, Qin Tang, Laura Garcia-Perez, Karin Pike-Overzet, Lars Anders, Alla Berezovskaya, Yi Zhou, Leonard I Zon, Donna S Neuberg, Adele K Fielding, Frank J T Staal, David M Langenau, Takaomi Sanda, Richard A Young, A Thomas Look
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. The Journal of experimental medicine 215 (7) (2018)
Joseph Mandelbaum, Ilya A Shestopalov, Rachel E Henderson, Nicole G Chau, Birgit Knoechel, Michael J Wick, Leonard I Zon
Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma. The Journal of experimental medicine 215 (10) (2018)
Christie Ciarlo, Charles K Kaufman, Beste Kinikoglu, Jonathan Michael, Song Yang, Christopher D Amato, Sasja Blokzijl-Franke, Jeroen den Hertog, Thorsten M Schlaeger, Yi Zhou, Eric Liao, Leonard I Zon
A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. eLife 6 (2017)
Leonard I Zon
Modeling human diseases: an education in interactions and interdisciplinary approaches. Disease models & mechanisms 9 (6) (2017)
Bradley W Blaser, Jessica L Moore, Elliott J Hagedorn, Brian Li, Raquel Riquelme, Asher E Lichtig, Song Yang, Yi Zhou, Owen J Tamplin, Vera Binder, Leonard I Zon
CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine 214 (4) (2017)
Dorit Hockman, Alan J Burns, Gerhard Schlosser, Keith P Gates, Benjamin Jevans, Alessandro Mongera, Shannon Fisher, Gokhan Unlu, Ela W Knapik, Charles K Kaufman, Christian Mosimann, Leonard I Zon, Joseph J Lancman, P Duc S Dong, Heiko Lickert, Abigail S Tucker, Clare V H Baker
Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. eLife 6 (2017)
Julie R Perlin, Anne L Robertson, Leonard I Zon
Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis. The Journal of experimental medicine 214 (10) (2017)
Nicholas G Crawford, Derek E Kelly, Matthew E B Hansen, Marcia Holsbach Beltrame, Shaohua Fan, Shanna L Bowman, Ethan Jewett, Alessia Ranciaro, Simon Thompson, Yancy Lo, Susanne P Pfeifer, Jeffrey D Jensen, Michael C Campbell, William Beggs, Farhad Hormozdiari, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Thomas Nyambo, Dawit Wolde Meskel, Gurja Belay, Jake Haut, null null, Harriet T Rothschild, Leonard I Zon, Yi Zhou, Michael A Kovacs, Mai Xu, Tongwu Zhang, Kevin Bishop, Jason Sinclair, Cecilia Rivas, Eugene Elliot, Jiyeon Choi, Shengchao A Li, Belynda D Hicks, Jason W Sinclair, Christian C Abnet, Dawn E Watkins-Chow, Elena Oancea, Yun S Song, Eleazar Eskin, Kevin K Brown, Michael S Marks, Stacie K Loftus, William J Pavan, Meredith Yeager, Stephen Chanock, Sarah A Tishkoff
Loci associated with skin pigmentation identified in African populations. Science (New York, N.Y.) 358 (6365) (2017)
Megan L Norris, Andrea Pauli, James A Gagnon, Nathan D Lord, Katherine W Rogers, Christian Mosimann, Leonard I Zon, Alexander F Schier
Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLife 6 (2017)
Stefano Volpi, Yasuhiro Yamazaki, Patrick M Brauer, Ellen van Rooijen, Atsuko Hayashida, Anne Slavotinek, Hye Sun Kuehn, Maja Di Rocco, Carlo Rivolta, Ileana Bortolomai, Likun Du, Kerstin Felgentreff, Lisa Ott de Bruin, Kazutaka Hayashida, George Freedman, Genni Enza Marcovecchio, Kelly Capuder, Prisni Rath, Nicole Luche, Elliott J Hagedorn, Antonella Buoncompagni, Beryl Royer-Bertrand, Silvia Clara Giliani, Pietro Luigi Poliani, Luisa Imberti, A Kerry Dobbs, Fabienne E Poulain, Alberto Martini, John Manis, Robert J Linhardt, Marita Bosticardo, Sergio Damian Rosenzweig, Hane Lee, Jennifer M Puck, Juan-Carlos Zúñiga-Pflücker, Leonard I Zon, Pyong Woo Park, Andrea Superti-Furga, Luigi Daniele Notarangelo
EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. The Journal of experimental medicine 214 (3) (2017)
Michelle Dang, Rachel E Henderson, Levi A Garraway, Leonard I Zon
Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies. Disease models & mechanisms 9 (7) (2016)