Nicole L La Gruta (Nicole La Gruta)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Venues

Nature communications

Journal of immunology (Baltimore, Md. : 1950)

Nature aging

Nature immunology

Monash University

Monash University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Monash University Apr 01 2016

Australia

Professor :: Biochemistry and Molecular Biology

University of Melbourne

Australia

Lab head :: Microbiology and Immunology

University of Melbourne

Australia

Group leader :: Microbiology and Immunology

University of Melbourne

Australia

postdoctoral associate :: Microbiology and Immunology

St. Jude Children's Research Hospital

United States

postdoctoral associate :: Immunology

Education History

Monash University

Australia

PHD :: Pathology and Immunology

Publications

Tiing Jen Loh, Jia Jia Lim, Claerwen M Jones, Hien Thy Dao, Mai T Tran, Daniel G Baker, Nicole L La Gruta, Hugh H Reid, Jamie Rossjohn
The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nature communications 15 (1) (2024)
Tiing Jen Loh, Jia Jia Lim, Claerwen M Jones, Hien Thy Dao, Mai T Tran, Daniel G Baker, Nicole L La Gruta, Hugh H Reid, Jamie Rossjohn
The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nature communications 15 (1) (2024)
Tiing Jen Loh, Jia Jia Lim, Claerwen M Jones, Hien Thy Dao, Mai T Tran, Daniel G Baker, Nicole L La Gruta, Hugh H Reid, Jamie Rossjohn
The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nature communications 15 (1) (2024)
Tiing Jen Loh, Jia Jia Lim, Claerwen M Jones, Hien Thy Dao, Mai T Tran, Daniel G Baker, Nicole L La Gruta, Hugh H Reid, Jamie Rossjohn
The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nature communications 15 (1) (2024)
Daniel Thiele, Nicole L La Gruta
Immune-checkpoint blockade protects aged mice from infection. Nature aging 4 (7) (2024)
Tiing Jen Loh, Jia Jia Lim, Claerwen M Jones, Hien Thy Dao, Mai T Tran, Daniel G Baker, Nicole L La Gruta, Hugh H Reid, Jamie Rossjohn
The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nature communications 15 (1) (2024)
Daniel Thiele, Nicole L La Gruta
Immune-checkpoint blockade protects aged mice from infection. Nature aging 4 (7) (2024)
Daniel Thiele, Nicole L La Gruta
Immune-checkpoint blockade protects aged mice from infection. Nature aging (2024)
Tabinda Hussain, Angela Nguyen, Carmel Daunt, Daniel Thiele, Ee Shan Pang, Jasmine Li, Aidil Zaini, Meredith O'Keeffe, Colby Zaph, Nicola Laraine Harris, Kylie M Quinn, Nicole L La Gruta
Helminth Infection-Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice. Journal of immunology (Baltimore, Md. : 1950) 210 (3) (2023)
Tabinda Hussain, Angela Nguyen, Carmel Daunt, Daniel Thiele, Ee Shan Pang, Jasmine Li, Aidil Zaini, Meredith O'Keeffe, Colby Zaph, Nicola Laraine Harris, Kylie M Quinn, Nicole L La Gruta
Helminth Infection-Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice. Journal of immunology (Baltimore, Md. : 1950) 210 (3) (2023)
Carolien E van de Sandt, Thi H O Nguyen, Nicholas A Gherardin, Jeremy Chase Crawford, Jerome Samir, Anastasia A Minervina, Mikhail V Pogorelyy, Simone Rizzetto, Christopher Szeto, Jasveen Kaur, Nicole Ranson, Sabrina Sonda, Alice Harper, Samuel J Redmond, Hayley A McQuilten, Tejas Menon, Sneha Sant, Xiaoxiao Jia, Kate Pedrina, Theo Karapanagiotidis, Natalie Cain, Suellen Nicholson, Zhenjun Chen, Ratana Lim, E Bridie Clemens, Auda Eltahla, Nicole L La Gruta, Jane Crowe, Martha Lappas, Jamie Rossjohn, Dale I Godfrey, Paul Glyndwr Thomas, Stephanie Gras, Katie Louise Flanagan, Fabio Luciani, Katherine Kedzierska
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan. Nature immunology (2023)
Tabinda Hussain, Angela Nguyen, Carmel Daunt, Daniel Thiele, Ee Shan Pang, Jasmine Li, Aidil Zaini, Meredith O'Keeffe, Colby Zaph, Nicola Laraine Harris, Kylie M Quinn, Nicole L La Gruta
Helminth Infection-Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice. Journal of immunology (Baltimore, Md. : 1950) 210 (3) (2023)
Jia Jia Lim, Claerwen M Jones, Tiing Jen Loh, Yi Tian Ting, Pirooz Zareie, Khai Lee Loh, Nathan J Felix, Anish Suri, Murray McKinnon, Frederik Stevenaert, Ravi Kumar Sharma, Lars Klareskog, Vivianne Malmström, Daniel G Baker, Anthony Wayne Purcell, Hugh H Reid, Nicole L La Gruta, Jamie Rossjohn
The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR. Science immunology 6 (58) (2022)
Christopher Szeto, Pirooz Zareie, Rushika C Wirasinha, Justin B Zhang, Andrea T Nguyen, Alan Riboldi-Tunnicliffe, Nicole L La Gruta, Stephanie Gras, Stephen R Daley
Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nature communications 13 (1) (2022)
Tabinda Hussain, Angela Nguyen, Carmel Daunt, Daniel Thiele, Ee Shan Pang, Jasmine Li, Aidil Zaini, Meredith O'Keeffe, Colby Zaph, Nicola Laraine Harris, Kylie M Quinn, Nicole L La Gruta
Helminth Infection-Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice. Journal of immunology (Baltimore, Md. : 1950) (2022)
Thi H O Nguyen, Marios Koutsakos, Carolien E van de Sandt, Jeremy Chase Crawford, Liyen Loh, Sneha Sant, Ludivine Grzelak, Emma K Allen, Tim Brahm, E Bridie Clemens, Maria Auladell, Luca Hensen, Zhongfang Wang, Simone Nüssing, Xiaoxiao Jia, Patrick Günther, Adam K Wheatley, Stephen J Kent, Malet Aban, Yi-Mo Deng, Karen L Laurie, Aeron C Hurt, Stephanie Gras, Jamie Rossjohn, Jane Crowe, Jianqing Xu, David C Jackson, Lorena E Brown, Nicole L La Gruta, Weisan Chen, Peter C Doherty, Stephen J Turner, Tom C Kotsimbos, Paul Glyndwr Thomas, Allen C Cheng, Katherine Kedzierska
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients. Nature communications 12 (1) (2021)
Andrea Di Pietro, Jack Polmear, Lucy Cooper, Timon Damelang, Tabinda Hussain, Lauren Hailes, Kristy O'Donnell, Vibha Udupa, Tian Mi, Simon P Preston, Areen Shtewe, Uri Hershberg, Stephen J Turner, Nicole L La Gruta, Amy W Chung, David Mathew Tarlinton, Christopher D Scharer, Kim L Good-Jacobson
Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection. Nature immunology (2021)
Mai T Tran, Pouya Faridi, Jia Jia Lim, Yi Tian Ting, Goodluck Onwukwe, Pushpak Bhattacharjee, Claerwen M Jones, Eleonora Tresoldi, Fergus J Cameron, Nicole L La Gruta, Anthony Wayne Purcell, Stuart I Mannering, Jamie Rossjohn, Hugh H Reid
T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8. Nature communications 12 (1) (2021)
Pirooz Zareie, Christopher Szeto, Carine Farenc, Sachith D Gunasinghe, Elizabeth Motunrayo Kolawole, Angela Nguyen, Chantelle Blyth, Xavier Y X Sng, Jasmine Li, Claerwen M Jones, Alex J Fulcher, Jesica R Jacobs, Qianru Wei, Lukasz Wojciech, Jan Petersen, Nicholas R J Gascoigne, Brian D Evavold, Katharina Gaus, Stephanie Gras, Jamie Rossjohn, Nicole L La Gruta
Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling. Science (New York, N.Y.) 372 (6546) (2021)
Xavier Y X Sng, Jasmine Li, Pirooz Zareie, Lisa M Assmus, Jason K C Lee, Claerwen M Jones, Stephen J Turner, Stephen R Daley, Kylie M Quinn, Nicole L La Gruta
The Impact of MHC Class I Dose on Development and Maintenance of the Polyclonal Naive CD8+ T Cell Repertoire. Journal of immunology (Baltimore, Md. : 1950) 204 (12) (2020)
Kylie M Quinn, Tabinda Hussain, Felix Kraus, Luke E Formosa, Wai Kit Lam, Michael J Dagley, Eleanor C Saunders, Lisa M Assmus, Erica Wynne-Jones, Liyen Loh, Carolien E van de Sandt, Lucy Cooper, Kim L Good-Jacobson, Katherine Kedzierska, Laura K Mackay, Malcolm J McConville, Georg Ramm, Michael T Ryan, Nicole L La Gruta
Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality. Nature communications 11 (1) (2020)
Kylie M Quinn, Tabinda Hussain, Felix Kraus, Luke E Formosa, Wai Kit Lam, Michael J Dagley, Eleanor C Saunders, Lisa M Assmus, Erica Wynne-Jones, Liyen Loh, Carolien E van de Sandt, Lucy Cooper, Kim L Good-Jacobson, Katherine Kedzierska, Laura K Mackay, Malcolm J McConville, Georg Ramm, Michael T Ryan, Nicole L La Gruta
Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality. Nature communications 11 (1) (2020)
Lisa M Assmus, Jing Guan, Ting Wu, Carine Farenc, Xavier Y X Sng, Pirooz Zareie, Angela Nguyen, Andrea T Nguyen, David Carl Tscharke, Paul Glyndwr Thomas, Jamie Rossjohn, Stephanie Gras, Nathan Paul Croft, Anthony Wayne Purcell, Nicole L La Gruta
Overlapping Peptides Elicit Distinct CD8+ T Cell Responses following Influenza A Virus Infection. Journal of immunology (Baltimore, Md. : 1950) 205 (7) (2020)
Melinda Y Hardy, Amy K Russell, Catherine Pizzey, Claerwen M Jones, Katherine A Watson, Nicole L La Gruta, Donald J Cameron, Jason A Tye-Din
Characterisation of clinical and immune reactivity to barley and rye ingestion in children with coeliac disease. Gut 69 (5) (2019)
Andreas Handel, Nicole L La Gruta, Paul Glyndwr Thomas
Simulation modelling for immunologists. Nature reviews. Immunology 20 (3) (2019)
Kylie M Quinn, Wan-Ting Kan, Katherine A Watson, Brian J Liddicoat, Natasha G Swan, Hayley McQuilten, Alice E Denton, Jasmine Li, Weisan Chen, Lorena E Brown, David C Jackson, Patrick C Reading, Peter C Doherty, Katherine Kedzierska, Lukasz Kedzierski, Stephen J Turner, Nicole L La Gruta
Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude. PloS one 12 (9) (2017)

Nicole L La Gruta.css-eqlu8i{font-size:small;padding-left:4px;} (Nicole La Gruta)

Publication Activity (10 Years)

Top Topics

Top Venues

Nicole L La Gruta (Nicole La Gruta)