Orian S Shirihai (Orian Shirihai)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 46

Top Topics

Top Venues

Nature communications

The EMBO journal

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil K Mahata, Orian S Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria. Science advances 10 (14) (2024)
Martin Picard, Eugene V Mosharov, Ayelet Rosenberg, Anna Monzel, Corey Osto, Linsey Stiles, Gorazd Rosoklija, Andrew Dwork, Snehal Bindra, Ya Zhang, Masashi Fujita, Madeline Mariani, Mihran Bakalian, David L Sulzer, Philip Lawrence De Jager, Vilas Menon, Orian S Shirihai, John Mann, Mark Underwood, Maura Boldrini, Michel Thiebaut de Schotten
A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity. Research square (2024)
Eugene V Mosharov, Ayelet M Rosenberg, Anna S Monzel, Corey A Osto, Linsey Stiles, Gorazd B Rosoklija, Andrew J Dwork, Snehal Bindra, Ya Zhang, Masashi Fujita, Madeline B Mariani, Mihran Bakalian, David L Sulzer, Philip Lawrence De Jager, Vilas Menon, Orian S Shirihai, J John Mann, Mark Underwood, Maura Boldrini, Michel Thiebaut de Schotten, Martin Picard
A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity. Research square (2024)
Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil K Mahata, Orian S Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria. Science advances 10 (14) (2024)
Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil K Mahata, Orian S Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria. Science advances 10 (14) (2024)
Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil K Mahata, Orian S Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria. Science advances 10 (14) (2024)
Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil K Mahata, Orian S Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria. Science advances 10 (14) (2024)
Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil K Mahata, Orian S Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria. Science advances 10 (14) (2024)
Rebecca Acin-Perez, Cristiane Benincá, Lucia Fernandez Del Rio, Cynthia Shu, Siyouneh Baghdasarian, Vanessa Zanette, Christoph Gerle, Chimari Jiko, Ramzi Khairallah, Shaharyar Khan, David Rincon Fernandez Pacheco, Byourak Shabane, Karel Erion, Ruchi Masand, Sundeep Dugar, Cristina Ghenoiu, George Schreiner, Linsey Stiles, Marc Liesa, Orian S Shirihai
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies. The EMBO journal (2023)
Lucia Fernandez Del Rio, Cristiane Benincá, Frankie Villalobos, Cynthia Shu, Linsey Stiles, Marc Liesa, Ajit S Divakaruni, Rebecca Acin-Perez, Orian S Shirihai
A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates. Life science alliance 6 (4) (2023)
Jialiu Zeng, Rebeca Acin-Perez, Essam A Assali, Andrew Martin, Alexandra J Brownstein, Anton Petcherski, Lucia Fernandez Del Rio, Ruiqing Xiao, Chih Hung Lo, Michaël Shum, Marc Liesa, Xue Han, Orian S Shirihai, Mark W Grinstaff
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. Nature communications 14 (1) (2023)
Jialiu Zeng, Rebeca Acin-Perez, Essam A Assali, Andrew Martin, Alexandra J Brownstein, Anton Petcherski, Lucia Fernandez Del Rio, Ruiqing Xiao, Chih Hung Lo, Michaël Shum, Marc Liesa, Xue Han, Orian S Shirihai, Mark W Grinstaff
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. Nature communications 14 (1) (2023)
Jialiu Zeng, Rebeca Acin-Perez, Essam A Assali, Andrew Martin, Alexandra J Brownstein, Anton Petcherski, Lucia Fernandez Del Rio, Ruiqing Xiao, Chih Hung Lo, Michaël Shum, Marc Liesa, Xue Han, Orian S Shirihai, Mark W Grinstaff
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. Nature communications 14 (1) (2023)
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason Thanh Lee, Masha V Poyurovsky, Kellen Olszewski, Travis S Laferriere-Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer. Nature 615 (7953) (2023)
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason Thanh Lee, Masha V Poyurovsky, Kellen Olszewski, Travis S Laferriere-Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer. Nature 615 (7953) (2023)
Pasquale Saggese, Aparamita Pandey, Martín Alcaraz, Eileen Fung, Abbie Hall, Jane Yanagawa, Erika F Rodriguez, Tristan R Grogan, Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Orian S Shirihai, Steven M Dubinett, Claudio R Scafoglio
Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma. Cancer research (2023)
Jialiu Zeng, Rebeca Acin-Perez, Essam A Assali, Andrew Martin, Alexandra J Brownstein, Anton Petcherski, Lucia Fernandez Del Rio, Ruiqing Xiao, Chih Hung Lo, Michaël Shum, Marc Liesa, Xue Han, Orian S Shirihai, Mark W Grinstaff
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. Nature communications 14 (1) (2023)
Amelia Palermo, Shen Li, Johanna Ten Hoeve, Akshay Chellappa, Alexandra Morris, Barbara Dillon, Feiyang Ma, Yijie Wang, Edward Cao, Byourak Shabane, Rebecca Acin-Perez, Anton Petcherski, Aldons J Lusis, Stanley L Hazen, Orian S Shirihai, Matteo Pellegrini, Vaithilingaraja Arumugaswami, Thomas Glen Graeber, Arjun Deb
A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. Communications biology 6 (1) (2023)
Rebecca Acin-Perez, Cristiane Benincá, Lucia Fernandez Del Rio, Cynthia Shu, Siyouneh Baghdasarian, Vanessa Zanette, Christoph Gerle, Chimari Jiko, Ramzi Khairallah, Shaharyar Khan, David Rincon Fernandez Pacheco, Byourak Shabane, Karel Erion, Ruchi Masand, Sundeep Dugar, Cristina Ghenoiu, George Schreiner, Linsey Stiles, Marc Liesa, Orian S Shirihai
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies. The EMBO journal (2023)
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason Thanh Lee, Masha V Poyurovsky, Kellen Olszewski, Travis S Laferriere-Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer. Nature 615 (7953) (2023)
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason Thanh Lee, Masha V Poyurovsky, Kellen Olszewski, Travis S Laferriere-Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer. Nature (2023)
Lucia Fernandez Del Rio, Cristiane Benincá, Frankie Villalobos, Cynthia Shu, Linsey Stiles, Marc Liesa, Ajit S Divakaruni, Rebecca Acin-Perez, Orian S Shirihai
A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates. Life science alliance 6 (4) (2023)
Jialiu Zeng, Rebeca Acin-Perez, Essam A Assali, Andrew Martin, Alexandra J Brownstein, Anton Petcherski, Lucia Fernandez Del Rio, Ruiqing Xiao, Chih Hung Lo, Michaël Shum, Marc Liesa, Xue Han, Orian S Shirihai, Mark W Grinstaff
Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease. Nature communications 14 (1) (2023)
Jennifer Ngo, Dong Wook Choi, Illana A Stanley, Linsey Stiles, Anthony J A Molina, Pei-Hsuan Chen, Ana Lako, Isabelle Chiao Han Sung, Rishov Goswami, Min-Young Kim, Nathanael Miller, Siyouneh Baghdasarian, Doyeon Kim-Vasquez, Anthony E Jones, Brett Roach, Vincent Gutierrez, Karel Erion, Ajit S Divakaruni, Marc Liesa, Nika N Danial, Orian S Shirihai
Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA. The EMBO journal (2023)
Lucia Fernandez Del Rio, Cristiane Benincá, Frankie Villalobos, Cynthia Shu, Linsey Stiles, Marc Liesa, Ajit S Divakaruni, Rebecca Acin-Perez, Orian S Shirihai
A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates. Life science alliance 6 (4) (2023)
Alexandra J Brownstein, Michaela Veliova, Rebecca Acin-Perez, Frankie Villalobos, Anton Petcherski, Alberto Tombolato, Marc Liesa, Orian S Shirihai
Mitochondria isolated from lipid droplets of white adipose tissue reveal functional differences based on lipid droplet size. Life science alliance 7 (2) (2023)
Brandon R Desousa, Kristen Ko Kim, Anthony E Jones, Andréa B Ball, Wei Y Hsieh, Pamela Swain, Danielle H Morrow, Alexandra J Brownstein, David A Ferrick, Orian S Shirihai, Andrew Neilson, David A Nathanson, George W Rogers, Brian P Dranka, Anne N Murphy, Charles Affourtit, Steven J Bensinger, Linsey Stiles, Natalia Romero, Ajit S Divakaruni
Calculation of ATP production rates using the Seahorse XF Analyzer. EMBO reports (2023)
Timothy M Moore, Lijing Cheng, Dane M Wolf, Jennifer Ngo, Mayuko Segawa, Xiaopeng Zhu, Alexander R Strumwasser, Yang Cao, Bethan L Clifford, Alice Ma, Philip O Scumpia, Orian S Shirihai, Thomas Q de Aguiar Vallim, Markku Laakso, Aldons J Lusis, Andrea L Hevener, Zhenqi Zhou
Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes. Nature communications 13 (1) (2022)
Kun Do Rhee, Yanjie Wang, Johanna Ten Hoeve, Linsey Stiles, Thao Thi Thu Nguyen, Xiangmei Zhang, Laurent Vergnes, Karen Reue, Orian S Shirihai, Dean Bok, Xian-Jie Yang
Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas. Nature communications 13 (1) (2022)
Prashant Rai, Kyathanahalli S Janardhan, Julie Meacham, Jennifer H Madenspacher, Wan-Chi Lin, Peer W F Karmaus, Jennifer Martinez, Quan-Zhen Li, Mei Yan, Jialiu Zeng, Mark W Grinstaff, Orian S Shirihai, Gregory A Taylor, Michael B Fessler
IRGM1 links mitochondrial quality control to autoimmunity. Nature immunology 22 (3) (2021)
Alexandra J Brownstein, Michaela Veliova, Rebecca Acin-Perez, Marc Liesa, Orian S Shirihai
ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity. Reviews in endocrine & metabolic disorders (2021)
Milica Momcilovic, Orian S Shirihai, Michael P Murphy, Carla M Koehler, Saman Sadeghi, David B Shackelford
Reply to: In vivo quantification of mitochondrial membrane potential. Nature 583 (7815) (2021)
Ning Shen, Sovannarith Korm, Theodoros Karantanos, Dun Li, Xiaoyu Zhang, Eleni Ritou, Hanfei Xu, Andrew Lam, Justin English, Wei-Xing Zong, Ching-Ti Liu, Orian S Shirihai, Hui Feng
DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer. Communications biology 4 (1) (2021)
Rebecca Acin-Perez, Salvador Iborra, Yolanda Martí-Mateos, Emma C L Cook, Ruth Conde-Garrosa, Anton Petcherski, Mª Del Mar Muñoz, Raquel Martínez de Mena, Karthickeyan Chella Krishnan, Concepción Jiménez, Juan Pedro Bolaños, Markku Laakso, Aldons J Lusis, Orian S Shirihai, David Sancho, José Antonio Enríquez
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity. Nature metabolism 2 (9) (2020)
Mayuko Segawa, Dane M Wolf, Nan W Hultgren, David S Williams, Alexander M van der Bliek, David B Shackelford, Marc Liesa, Orian S Shirihai
Quantification of cristae architecture reveals time-dependent characteristics of individual mitochondria. Life science alliance 3 (7) (2020)
Michaela Veliova, Caroline M Ferreira, Ilan Y Benador, Anthony E Jones, Kiana Mahdaviani, Alexandra J Brownstein, Brandon R Desousa, Rebecca Acin-Perez, Anton Petcherski, Essam A Assali, Linsey Stiles, Ajit S Divakaruni, Marc Prentki, Barbara E Corkey, Marc Liesa, Marcus F Oliveira, Orian S Shirihai
Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling. EMBO reports 21 (12) (2020)
Arun Kumar Kondadi, Ruchika Anand, Sebastian Hänsch, Jennifer Urbach, Thomas Zobel, Dane M Wolf, Mayuko Segawa, Marc Liesa, Orian S Shirihai, Stefanie Weidtkamp-Peters, Andreas S Reichert
Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner. EMBO reports 21 (3) (2020)
Rebecca Acin-Perez, Ilan Y Benador, Anton Petcherski, Michaela Veliova, Gloria A Benavides, Sylviane Lagarrigue, Arianne Caudal, Laurent Vergnes, Anne N Murphy, Georgios Karamanlidis, Rong Tian, Karen Reue, Jonathan Wanagat, Harold Sacks, Francesca Amati, Victor M Darley-Usmar, Marc Liesa, Ajit S Divakaruni, Linsey Stiles, Orian S Shirihai
A novel approach to measure mitochondrial respiration in frozen biological samples. The EMBO journal 39 (13) (2020)
Essam A Assali, Anthony E Jones, Michaela Veliova, Rebeca Acín-Pérez, Mahmoud Taha, Nathanael Miller, Michaël Shum, Marcus F Oliveira, Guy Las, Marc Liesa, Israel Sekler, Orian S Shirihai
NCLX prevents cell death during adrenergic activation of the brown adipose tissue. Nature communications 11 (1) (2020)
Evan P Taddeo, Nour Alsabeeh, Siyouneh Baghdasarian, Jakob D Wikstrom, Eleni Ritou, Samuel Sereda, Karel Erion, Jin Li, Linsey Stiles, Muhamad Abdulla, Zachary Swanson, Joshua J Wilhelm, Melena D Bellin, Richard G Kibbey, Marc Liesa, Orian S Shirihai
Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels. Diabetes 69 (2) (2019)
Marc Liesa, Alexander M van der Bliek, Orian S Shirihai
To Fis or not to Fuse? This is the question! The EMBO journal 38 (8) (2019)
Dane M Wolf, Mayuko Segawa, Arun Kumar Kondadi, Ruchika Anand, Sean T Bailey, Andreas S Reichert, Alexander M van der Bliek, David B Shackelford, Marc Liesa, Orian S Shirihai
Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent. The EMBO journal 38 (22) (2019)
Marc Liesa, Orian S Shirihai
Mitochondrial adaptation in obesity is a ClpPicated business. EMBO reports 19 (6) (2018)
Aida Rodríguez-Nuevo, Angels Díaz-Ramos, Eduard Noguera, Francisco Díaz-Sáez, Xavier Duran, Juan Pablo Muñoz, Montserrat Romero, Natàlia Plana, David Sebastián, Caterina Tezze, Vanina Romanello, Francesc Ribas, Jordi Seco, Evarist Planet, Susan R Doctrow, Javier González, Miquel Borràs, Marc Liesa, Manuel Palacín, Joan Vendrell, Francesc Villarroya, Marco Sandri, Orian S Shirihai, Antonio Zorzano
Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. The EMBO journal 37 (10) (2018)
Jeong-A Lim, Lishu Li, Orian S Shirihai, Kyle M Trudeau, Rosa Puertollano, Nina Raben
Modulation of mTOR signaling as a strategy for the treatment of Pompe disease. EMBO molecular medicine 9 (3) (2017)
Kiana Mahdaviani, Ilan Y Benador, Shi Su, Raffi A Gharakhanian, Linsey Stiles, Kyle M Trudeau, Maria Cardamone, Violeta Enríquez-Zarralanga, Eleni Ritou, Tamar Aprahamian, Marcus F Oliveira, Barbara E Corkey, Valentina Perissi, Marc Liesa, Orian S Shirihai
Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis. EMBO reports 18 (7) (2017)