Michael P Murphy (M P Murphy)

ResearcherID Ciência ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 65

Top Venues

Nature

Nature communications

The Journal of experimental biology

Cancers

University of Cambridge

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cambridge

United Kingdom

Professor of Mitochondrial Redox Biology

University of Cambridge

United Kingdom

Programme Leader :: MRC Mitochondrial Biology Unit

University of Otago

New Zealand

Lecturer/senior lecturer/associate professor :: Biochemistry

Education History

University of Cambridge

United Kingdom

PHD :: Biochemistry

Publications

Chris G Faulkes, Thomas R Eykyn, Jan Lj Miljkovic, James D Gilbert, Rebecca L Charles, Hiran A Prag, Nikayla Patel, Daniel W Hart, Michael P Murphy, Nigel C Bennett, Dunja Aksentijević
Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles. Nature communications 15 (1) (2024)
Luca Peruzzotti-Jametti, C M Willis, G Krzak, R Hamel, L Pirvan, Rosana-Bristena Ionescu, J A Reisz, Hiran A Prag, M E Garcia-Segura, V Wu, Y Xiang, B Barlas, Alva M Casey, A M R van den Bosch, Alexandra M Nicaise, L Roth, G R Bates, H Huang, P Prasad, A E Vincent, Christian Frezza, Carlos Pardo-Hernández, Gabriel Balmus, Zoltán Takáts, John C Marioni, Angelo D'Alessandro, Michael P Murphy, Irina I Mohorianu, Stefano Pluchino
Mitochondrial complex I activity in microglia sustains neuroinflammation. Nature (2024)
Yu Jin Chung, Zoe Hoare, Friedrich Baark, Chak Shun Yu, Jia Guo, William Fuller, Richard Southworth, Dörthe Magdalena Katschinski, Michael P Murphy, Thomas R Eykyn, Michael J Shattock
Elevated Na is a dynamic and reversible modulator of mitochondrial metabolism in the heart. Nature communications 15 (1) (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Luca Peruzzotti-Jametti, C M Willis, G Krzak, R Hamel, L Pirvan, Rosana-Bristena Ionescu, J A Reisz, Hiran A Prag, M E Garcia-Segura, V Wu, Y Xiang, B Barlas, Alva M Casey, A M R van den Bosch, Alexandra M Nicaise, L Roth, G R Bates, H Huang, P Prasad, A E Vincent, Christian Frezza, Carlos Pardo-Hernández, Gabriel Balmus, Zoltán Takáts, John C Marioni, Angelo D'Alessandro, Michael P Murphy, Irina I Mohorianu, Stefano Pluchino
Mitochondrial complex I activity in microglia sustains neuroinflammation. Nature (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Luca Peruzzotti-Jametti, C M Willis, G Krzak, R Hamel, L Pirvan, Rosana-Bristena Ionescu, J A Reisz, Hiran A Prag, M E Garcia-Segura, V Wu, Y Xiang, B Barlas, Alva M Casey, A M R van den Bosch, Alexandra M Nicaise, L Roth, G R Bates, H Huang, P Prasad, A E Vincent, Christian Frezza, Carlos Pardo-Hernández, Gabriel Balmus, Zoltán Takáts, John C Marioni, Angelo D'Alessandro, Michael P Murphy, Irina I Mohorianu, Stefano Pluchino
Mitochondrial complex I activity in microglia sustains neuroinflammation. Nature 628 (8006) (2024)
Chris G Faulkes, Thomas R Eykyn, Jan Lj Miljkovic, James D Gilbert, Rebecca L Charles, Hiran A Prag, Nikayla Patel, Daniel W Hart, Michael P Murphy, Nigel C Bennett, Dunja Aksentijević
Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles. Nature communications 15 (1) (2024)
Yu Jin Chung, Zoe Hoare, Friedrich Baark, Chak Shun Yu, Jia Guo, William Fuller, Richard Southworth, Dörthe Magdalena Katschinski, Michael P Murphy, Thomas R Eykyn, Michael J Shattock
Elevated Na is a dynamic and reversible modulator of mitochondrial metabolism in the heart. Nature communications 15 (1) (2024)
Luca Peruzzotti-Jametti, C M Willis, G Krzak, R Hamel, L Pirvan, Rosana-Bristena Ionescu, J A Reisz, Hiran A Prag, M E Garcia-Segura, V Wu, Y Xiang, B Barlas, Alva M Casey, A M R van den Bosch, Alexandra M Nicaise, L Roth, G R Bates, H Huang, P Prasad, A E Vincent, Christian Frezza, Carlos Pardo-Hernández, Gabriel Balmus, Zoltán Takáts, John C Marioni, Angelo D'Alessandro, Michael P Murphy, Irina I Mohorianu, Stefano Pluchino
Mitochondrial complex I activity in microglia sustains neuroinflammation. Nature 628 (8006) (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Chris G Faulkes, Thomas R Eykyn, Jan Lj Miljkovic, James D Gilbert, Rebecca L Charles, Hiran A Prag, Nikayla Patel, Daniel W Hart, Michael P Murphy, Nigel C Bennett, Dunja Aksentijević
Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles. Nature communications 15 (1) (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Luca Peruzzotti-Jametti, C M Willis, G Krzak, R Hamel, L Pirvan, Rosana-Bristena Ionescu, J A Reisz, Hiran A Prag, M E Garcia-Segura, V Wu, Y Xiang, B Barlas, Alva M Casey, A M R van den Bosch, Alexandra M Nicaise, L Roth, G R Bates, H Huang, P Prasad, A E Vincent, Christian Frezza, Carlos Pardo-Hernández, Gabriel Balmus, Zoltán Takáts, John C Marioni, Angelo D'Alessandro, Michael P Murphy, Irina I Mohorianu, Stefano Pluchino
Mitochondrial complex I activity in microglia sustains neuroinflammation. Nature 628 (8006) (2024)
Yu Jin Chung, Zoe Hoare, Friedrich Baark, Chak Shun Yu, Jia Guo, William Fuller, Richard Southworth, Dörthe Magdalena Katschinski, Michael P Murphy, Thomas R Eykyn, Michael J Shattock
Elevated Na is a dynamic and reversible modulator of mitochondrial metabolism in the heart. Nature communications 15 (1) (2024)
Erik Schoenmakers, Federica Marelli, Helle F Jørgensen, W. Edward Visser, Carla Moran, Stefan Groeneweg, Carolina Avalos, Sean Joseph Jurgens, Nichola Figg, Alison Finigan, Neha Wali, Maura Agostini, Hannah Wardle-Jones, Greta Lyons, Rosemary Rusk, Deepa Gopalan, Philip Twiss, Jacob J Visser, Martin Goddard, Samer A M Nashef, Robin Heijmen, Paul Clift, Sanjay Sinha, James Paul Pirruccello, Patrick T Ellinor, Elisabeth M Busch-Nentwich, Ramiro Ramirez-Solis, Michael P Murphy, Luca Persani, Martin R Bennett, Krishna Chatterjee
Selenoprotein deficiency disorder predisposes to aortic aneurysm formation. Nature communications 14 (1) (2023)
Richard E Jones, Anja V Gruszczyk, Christina Schmidt, Daniel J Hammersley, Lukas Mach, Michael Lee, Joyce Wong, Ming Yang, Suzan Hatipoglu, Amrit S Lota, Sam N Barnett, Rebecca Toscano-Rivalta, Ruth Owen, Shahzad Raja, Fabio De Robertis, Hassiba Smail, Anthony De-Souza, Ulrich Stock, Peter Kellman, Julian Griffin, Marc-Emmanuel Dumas, Jack L Martin, Kourosh Saeb-Parsy, Ali Vazir, John G F Cleland, Dudley John Pennell, Sunil K Bhudia, Brian P Halliday, Michela Noseda, Christian Frezza, Michael P Murphy, Sanjay K Prasad
Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease. Nature cardiovascular research 2 (8) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature 615 (7952) (2023)
Richard E Jones, Anja V Gruszczyk, Christina Schmidt, Daniel J Hammersley, Lukas Mach, Michael Lee, Joyce Wong, Ming Yang, Suzan Hatipoglu, Amrit S Lota, Sam N Barnett, Rebecca Toscano-Rivalta, Ruth Owen, Shahzad Raja, Fabio De Robertis, Hassiba Smail, Anthony De-Souza, Ulrich Stock, Peter Kellman, Julian Griffin, Marc-Emmanuel Dumas, Jack L Martin, Kourosh Saeb-Parsy, Ali Vazir, John G F Cleland, Dudley John Pennell, Sunil K Bhudia, Brian P Halliday, Michela Noseda, Christian Frezza, Michael P Murphy, Sanjay K Prasad
Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease. Nature cardiovascular research 2 (8) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature 615 (7952) (2023)
Valerie B O'Donnell, Nils H Schebb, Ginger L Milne, Michael P Murphy, Christopher P Thomas, Dieter Steinhilber, Stacy Gelhaus Wendell, Hartmut Kühn, Michael H Gelb, Per-Johan Jakobsson, Ian A Blair, Robert C Murphy, Bruce A Freeman, Alan R Brash, Garret A FitzGerald
Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Nature communications 14 (1) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature 615 (7952) (2023)
Richard E Jones, Anja V Gruszczyk, Christina Schmidt, Daniel J Hammersley, Lukas Mach, Michael Lee, Joyce Wong, Ming Yang, Suzan Hatipoglu, Amrit S Lota, Sam N Barnett, Rebecca Toscano-Rivalta, Ruth Owen, Shahzad Raja, Fabio De Robertis, Hassiba Smail, Anthony De-Souza, Ulrich Stock, Peter Kellman, Julian Griffin, Marc-Emmanuel Dumas, Jack L Martin, Kourosh Saeb-Parsy, Ali Vazir, John G F Cleland, Dudley John Pennell, Sunil K Bhudia, Brian P Halliday, Michela Noseda, Christian Frezza, Michael P Murphy, Sanjay K Prasad
Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease. Nature cardiovascular research 2 (8) (2023)
Hiran A Prag, Michael P Murphy, Thomas Krieg
Preventing mitochondrial reverse electron transport as a strategy for cardioprotection. Basic research in cardiology 118 (1) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature (2023)
Fay M Allen, Ana S H Costa, Anja V Gruszczyk, Georgina R Bates, Hiran A Prag, Efterpi Nikitopoulou, Carlo Viscomi, Christian Frezza, Andrew M James, Michael P Murphy
Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation. FEBS letters (2022)
Gabriel Sturm, Anna S Monzel, Kalpita R Karan, Jeremy Michelson, Sarah A Ware, Beckey Trinh, Jue Lin, Céline Bris, Balaji Santhanam, Michael P Murphy, Morgan E Levine, Steve Horvath, Daniel W Belsky, Shuang Wang, Vincent Procaccio, Brett A Kaufman, Michio Hirano, Martin Picard
A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations. Scientific data 9 (1) (2022)
Tania Capeloa, Joanna Krzystyniak, Amanda Canas Rodriguez, Valéry L Payen, Luca X Zampieri, Erica Pranzini, Françoise Derouane, Thibaut Vazeille, Caroline Bouzin, Fran Ois P Duhoux, Michael P Murphy, Paolo Ettore Porporato, Pierre Sonveaux
MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice. Cancers 14 (6) (2022)
Helmut Sies, Vsevolod V Belousov, Navdeep S Chandel, Michael Jonathan Davies, Dean P Jones, Giovanni E Mann, Michael P Murphy, Masayuki Yamamoto, Christine C Winterbourn
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology. Nature reviews. Molecular cell biology 23 (7) (2022)
Michael P Murphy, Hülya Bayir, Vsevolod Belousov, Christopher J Chang, Kelvin J A Davies, Michael Jonathan Davies, Tobias P Dick, Toren Finkel, Henry J Forman, Yvonne Janssen-Heininger, David Gems, Valerian E Kagan, Balaraman Kalyanaraman, Nils-Göran Larsson, Ginger L Milne, Thomas Nyström, Henrik E Poulsen, Rafael Radi, Holly Van Remmen, Paul T Schumacker, Paul J Thornalley, Shinya Toyokuni, Christine C Winterbourn, Hui-Yong Yin, Barry Halliwell
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo. Nature metabolism 4 (6) (2022)
Tania Capeloa, Justine A Van de Velde, Donatienne d'Hose, Sara G Lipari, Françoise Derouane, Loïc Hamelin, Marie Bedin, Thibaut Vazeille, Fran Ois P Duhoux, Michael P Murphy, Paolo Ettore Porporato, Bernard Gallez, Pierre Sonveaux
Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice. Cancers 14 (19) (2022)
Francisco J Roca, Laura J Whitworth, Hiran A Prag, Michael P Murphy, Lalita Ramakrishnan
Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport. Science (New York, N.Y.) 376 (6600) (2022)
William Rae, John M Sowerby, Dorit Verhoeven, Mariam M Youssef, Prasanti Kotagiri, Natalia Savinykh, Eve L Coomber, Alexis Boneparth, Angela Chan, Chun Gong, Machiel H Jansen, Romy du Long, Giorgia Santilli, Ilenia Simeoni, Jonathan Stephens, Kejia Wu, Marta Zinicola, Hana Lango Allen, Helen Baxendale, Dinakantha Kumararatne, Effrossyni Gkrania-Klotsas, Selma Cecilia Scheffler-Mendoza, Marco Antonio Yamazaki-Nakashimada, Laura Berrón Ruiz, Cesar Mauricio Rojas-Maruri, Saul Oswaldo Lugo-Reyes, Paul A Lyons, Anthony P Williams, Daniel James Hodson, Gail A Bishop, Adrian J Thrasher, David C Thomas, Michael P Murphy, Timothy J Vyse, Joshua D Milner, Taco W Kuijpers, Kenneth G C Smith
Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations. Science immunology 7 (74) (2022)
Michael P Murphy, Edward T Chouchani
Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel. Nature chemical biology 18 (5) (2022)
Tania Capeloa, Joanna Krzystyniak, Donatienne d'Hose, Amanda Canas Rodriguez, Valery L Payen, Luca X Zampieri, Justine A Van de Velde, Zohra Benyahia, Erica Pranzini, Thibaut Vazeille, Maude Fransolet, Caroline Bouzin, Davide Brusa, Carine Michiels, Bernard Gallez, Michael P Murphy, Paolo Ettore Porporato, Pierre Sonveaux
MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity. Cancers 14 (6) (2022)
Lisa Tilokani, Fiona M Russell, Stevie Hamilton, Daniel M Virga, Mayuko Segawa, Vincent Paupe, Anja V Gruszczyk, Margherita Protasoni, Luis-Carlos Tabara, Mark Johnson, Hanish Anand, Michael P Murphy, David Grahame Hardie, Franck Polleux, Julien Prudent
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology. Science advances 8 (45) (2022)
Hiran A Prag, Michael P Murphy
mtDNA mutations help support cancer cells. Nature cancer 1 (10) (2022)
Jack L Martin, Ana S H Costa, Anja V Gruszczyk, Timothy E Beach, Fay M Allen, Hiran A Prag, Elizabeth C Hinchy, Krishnaa T A Mahbubani, Mazin Hamed, Laura Tronci, Efterpi Nikitopoulou, Andrew M James, Thomas Krieg, Alan J Robinson, Margaret M Huang, Stuart T Caldwell, Angela Logan, Laura Pala, Richard C Hartley, Christian Frezza, Kourosh Saeb Parsy, Michael P Murphy
Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nature metabolism 1 (2021)
Sih Min Tan, Runa S J Lindblom, Mark Ziemann, Adrienne Laskowski, Cesare Granata, Matthew Snelson, Vicki Thallas-Bonke, Assam El-Osta, Carlos D Baeza-Garza, Stuart T Caldwell, Richard C Hartley, Thomas Krieg, Mark E Cooper, Michael P Murphy, Melinda T Coughlan
Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide. Nutrients 13 (5) (2021)
Dylan Gerard Ryan, Ming Yang, Hiran A Prag, Giovanny Rodriguez Blanco, Efterpi Nikitopoulou, Marc Segarra-Mondejar, Christopher A Powell, Timothy Young, Nils Burger, Jan Lj Miljkovic, Michal Minczuk, Michael P Murphy, Alex von Kriegsheim, Christian Frezza
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism. eLife 10 (2021)
Fotios Sampaziotis, Daniele Muraro, Olivia C Tysoe, Stephen J Sawiak, Timothy E Beach, Edmund M Godfrey, Sara S Upponi, Teresa Brevini, Brandon T Wesley, Jose Garcia-Bernardo, Krishnaa T A Mahbubani, Giovanni Canu, Richard Gieseck, Natalie L Berntsen, Victoria L Mulcahy, Keziah Crick, Corrina Fear, Sharayne Robinson, Lisa Swift, Laure Gambardella, Johannes Bargehr, Daniel Ortmann, Stephanie E Brown, Anna Osnato, Michael P Murphy, Gareth Corbett, William T H Gelson, George F Mells, Peter Humphreys, Susan E Davies, Irum Amin, Paul Gibbs, Sanjay Sinha, Sarah A Teichmann, Andrew J Butler, Teik Choon See, Espen Melum, Christopher J E Watson, Kourosh Saeb Parsy, Ludovic Vallier
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver. Science (New York, N.Y.) 371 (6531) (2021)
Milica Momcilovic, Orian S Shirihai, Michael P Murphy, Carla M Koehler, Saman Sadeghi, David B Shackelford
Reply to: In vivo quantification of mitochondrial membrane potential. Nature 583 (7815) (2021)
Stuart T Caldwell, Sean N O'Byrne, Calum Wilson, Filip Cvetko, Michael P Murphy, John G McCarron, Richard C Hartley
Photoactivated release of membrane impermeant sulfonates inside cells. Chemical communications (Cambridge, England) 57 (32) (2021)
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R Bridges, Hiran A Prag, Daniel N Grba, Carlo Viscomi, Andrew M James, Amin Mottahedin, Thomas Krieg, Michael P Murphy, Judy Hirst
Structural basis for a complex I mutation that blocks pathological ROS production. Nature communications 12 (1) (2021)
Stephen C Cunnane, Eugenia Trushina, Cecilie Morland, Alessandro Prigione, Gemma Casadesus, Zane B Andrews, M Flint Beal, Linda H Bergersen, Roberta D Brinton, Suzanne de la Monte, Anne Eckert, Jenni Harvey, Ross Jeggo, Jack H Jhamandas, Oliver Kann, Clothide Mannoury la Cour, William F Martin, Gilles Mithieux, Paula I Moreira, Michael P Murphy, Klaus-Armin Nave, Tal Nuriel, Stéphane H R Oliet, Frédéric Saudou, Mark P Mattson, Russell H Swerdlow, Mark J Millan
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nature reviews. Drug discovery 19 (9) (2020)
Kimberley J Botting, Katie L Skeffington, Y Niu, Beth A Allison, Kirsty L Brain, Nozomi Itani, C Beck, A Logan, Andrew J Murray, Michael P Murphy, Dino A Giussani
Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction. Science advances 6 (34) (2020)
Amanda Bundgaard, Andrew M James, Michael E Harbour, Michael P Murphy, Angela Fago
Stable mitochondrial CICIII2 supercomplex interactions in reptiles compared to homeothermic vertebrates. The Journal of experimental biology (2020)
Kerstin N Timm, Charith Perera, Vicky Ball, John Aaron Henry, Jack J Miller, Matthew Kerr, James A West, Eshita Sharma, John Broxholme, Angela Logan, Dragana Savic, Michael S Dodd, Julian Leether Griffin, Michael P Murphy, Lisa C Heather, Damian J Tyler
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI. Communications biology 3 (1) (2020)
Michael P Murphy, Luke Anthony John O'Neill
How should we talk about metabolism? Nature immunology 21 (7) (2020)
Noor E W D Teulings, Tessa A C Garrud, Youguo Niu, Katie L Skeffington, Christian Beck, Nozomi Itani, Fiona G Conlon, Kimberley J Botting, Lisa M Nicholas, Thomas J Ashmore, Heather L Blackmore, Wen Tong, Emily J Camm, Jan B Derks, Angela Logan, Michael P Murphy, Susan E Ozanne, Dino A Giussani
Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34 (7) (2020)
Amanda Bundgaard, Andrew M James, Michael E Harbour, Michael P Murphy, Angela Fago
Stable mitochondrial CICIII2 supercomplex interactions in reptiles versus homeothermic vertebrates. The Journal of experimental biology 223 (Pt 12) (2020)
Kuanxing Gao, Man Cheng, Xinxin Zuo, Jin-Zhong Lin, Kurt Hoogewijs, Michael P Murphy, Xiang-Dong Fu, Xiaorong Zhang
Active RNA interference in mitochondria. Cell research 31 (2) (2020)
Chenzhi Jing, Tomas Castro-Dopico, Nathan Richoz, Zewen Kelvin Tuong, John Robert Ferdinand, Laurence S C Lok, Kevin W Loudon, Gemma D Banham, Rebeccah J Mathews, Zaeem Cader, Susan Fitzpatrick, Kathleen R Bashant, Mariana J Kaplan, Arthur Kaser, Randall S Johnson, Michael P Murphy, Richard M Siegel, Menna R Clatworthy
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis. Proceedings of the National Academy of Sciences of the United States of America 117 (26) (2020)
Karen A Fortner, Luz P Blanco, Iwona Buskiewicz, Nick Huang, Pamela C Gibson, Deborah L Cook, Hege L Pedersen, Peter S T Yuen, Michael P Murphy, Andras Perl, Mariana J Kaplan, Ralph C Budd
Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice. Lupus science & medicine 7 (1) (2020)
Gigi Y Lau, Sabine Arndt, Michael P Murphy, Jeffrey G Richards
Species- and tissue-specific differences in ROS metabolism during exposure to hypoxia and hyperoxia plus recovery in marine sculpins. The Journal of experimental biology 222 (Pt 22) (2019)
Silvia Galván-Peña, Richard G Carroll, Carla Newman, Elizabeth C Hinchy, Eva Palsson-McDermott, Elektra K Robinson, Sergio Covarrubias, Alan Nadin, Andrew M James, Moritz Haneklaus, Susan Carpenter, Vincent P Kelly, Michael P Murphy, Louise K Modis, Luke A O'Neill
Malonylation of GAPDH is an inflammatory signal in macrophages. Nature communications 10 (1) (2019)
Gigi Y Lau, Nicholas Barts, Richard C Hartley, Michael Tobler, Jeffrey G Richards, Michael P Murphy, Sabine Arndt
Detection of changes in mitochondrial hydrogen sulfide i n vivo in the fish model Poecilia mexicana (Poeciliidae). Biology open 8 (5) (2019)
Michael P Murphy
Rerouting metabolism to activate macrophages. Nature immunology 20 (9) (2019)
Amanda Bundgaard, Andrew M James, Anja V Gruszczyk, Jack Martin, Michael P Murphy, Angela Fago
Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. Scientific reports 9 (1) (2019)
Timothy J Humpton, Brinda Alagesan, Gina M DeNicola, Dan Lu, Georgi N Yordanov, Carl S Leonhardt, Melissa A Yao, Maya N Zaatari, Youngkyu Park, Jeremy N Skepper, Kay F Macleod, Pedro A Perez-Mancera, Michael P Murphy, Gerard I Evan, Karen H Vousden, David A Tuveson
Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer. Cancer discovery 9 (9) (2019)
Elizabeth C Hinchy, Anja V Gruszczyk, Robin Willows, Naveenan Navaratnam, Andrew R Hall, Georgina Bates, Thomas P Bright, Thomas Krieg, David Carling, Michael P Murphy
Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. The Journal of biological chemistry 293 (44) (2018)
Matthew Hancock, Anne D Hafstad, Adam A Nabeebaccus, Norman Catibog, Angela Logan, Ioannis Smyrnias, Synne S Hansen, Johanna Lanner, Katrin Schroder, Michael P Murphy, Ajay M Shah, Min Zhang
Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. eLife 7 (2018)
Ellen L Robb, Andrew R Hall, Tracy A Prime, Simon Eaton, Marten Szibor, Carlo Viscomi, Andrew M James, Michael P Murphy
Control of mitochondrial superoxide production by reverse electron transport at complex I. The Journal of biological chemistry 293 (25) (2018)

Michael P Murphy.css-eqlu8i{font-size:small;padding-left:4px;} (M P Murphy)

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Michael P Murphy (M P Murphy)